Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	47
Gene name	ATP citrate lyase
Gene symbol	ACLY
Synonyms (NCBI Gene)	ACLATPCLCLATP
Chromosome	17
Chromosome location	17q21.2
Summary	ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety

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miRTarBase ID	miRNA	Experiments	Reference
MIRT049373	hsa-miR-92a-3p	CLASH	23622248
MIRT049373	hsa-miR-92a-3p	CLASH	23622248
MIRT047450	hsa-miR-10b-5p	CLASH	23622248
MIRT045906	hsa-miR-125b-5p	CLASH	23622248
MIRT045416	hsa-miR-149-5p	CLASH	23622248
MIRT045416	hsa-miR-149-5p	CLASH	23622248
MIRT044080	hsa-miR-361-5p	CLASH	23622248
MIRT042918	hsa-miR-324-3p	CLASH	23622248
MIRT042069	hsa-miR-484	CLASH	23622248
MIRT040866	hsa-miR-18a-3p	CLASH	23622248
MIRT039123	hsa-miR-769-3p	CLASH	23622248
MIRT038850	hsa-miR-93-3p	CLASH	23622248
MIRT038673	hsa-miR-10a-3p	CLASH	23622248
MIRT037071	hsa-miR-877-3p	CLASH	23622248
MIRT036343	hsa-miR-1229-3p	CLASH	23622248
MIRT036222	hsa-miR-320b	CLASH	23622248
MIRT732501	hsa-miR-5580-3p	Microarray	32597160
MIRT756115	hsa-miR-214-3p	Luciferase reporter assayWestern blottingqRT-PCRFlow cytometry	37747441
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762692	hsa-miR-1244	CLIP-seq
MIRT762693	hsa-miR-1253	CLIP-seq
MIRT762694	hsa-miR-1258	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT762696	hsa-miR-1289	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762699	hsa-miR-22	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT762705	hsa-miR-3189-3p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762707	hsa-miR-3655	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT762714	hsa-miR-3973	CLIP-seq
MIRT762715	hsa-miR-4266	CLIP-seq
MIRT762716	hsa-miR-4271	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT762718	hsa-miR-4311	CLIP-seq
MIRT762719	hsa-miR-4499	CLIP-seq
MIRT762720	hsa-miR-4525	CLIP-seq
MIRT762721	hsa-miR-4535	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762726	hsa-miR-4723-5p	CLIP-seq
MIRT762727	hsa-miR-4725-3p	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762730	hsa-miR-4764-5p	CLIP-seq
MIRT762731	hsa-miR-4776-5p	CLIP-seq
MIRT762732	hsa-miR-4781-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762737	hsa-miR-518a-5p	CLIP-seq
MIRT762738	hsa-miR-527	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762745	hsa-miR-625	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT762749	hsa-miR-711	CLIP-seq
MIRT762750	hsa-miR-885-3p	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762753	hsa-miR-1202	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762692	hsa-miR-1244	CLIP-seq
MIRT762754	hsa-miR-1250	CLIP-seq
MIRT762694	hsa-miR-1258	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT762696	hsa-miR-1289	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762699	hsa-miR-22	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT762763	hsa-miR-3120-5p	CLIP-seq
MIRT762764	hsa-miR-3148	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT762765	hsa-miR-3155	CLIP-seq
MIRT762766	hsa-miR-3155b	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT762705	hsa-miR-3189-3p	CLIP-seq
MIRT762767	hsa-miR-3194-5p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762770	hsa-miR-3667-5p	CLIP-seq
MIRT762771	hsa-miR-3688-3p	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762774	hsa-miR-3915	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762775	hsa-miR-3928	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT762776	hsa-miR-3972	CLIP-seq
MIRT762714	hsa-miR-3973	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762715	hsa-miR-4266	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT762778	hsa-miR-4422	CLIP-seq
MIRT762719	hsa-miR-4499	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT762721	hsa-miR-4535	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT762781	hsa-miR-4645-5p	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762782	hsa-miR-4673	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762784	hsa-miR-4690-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762730	hsa-miR-4764-5p	CLIP-seq
MIRT762731	hsa-miR-4776-5p	CLIP-seq
MIRT762732	hsa-miR-4781-3p	CLIP-seq
MIRT762786	hsa-miR-4793-5p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT762787	hsa-miR-486-5p	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762737	hsa-miR-518a-5p	CLIP-seq
MIRT762738	hsa-miR-527	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762789	hsa-miR-550a	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762790	hsa-miR-614	CLIP-seq
MIRT762791	hsa-miR-626	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT762792	hsa-miR-7	CLIP-seq
MIRT762749	hsa-miR-711	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT762750	hsa-miR-885-3p	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762753	hsa-miR-1202	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT1924845	hsa-miR-1298	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT1924846	hsa-miR-217	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT762763	hsa-miR-3120-5p	CLIP-seq
MIRT762765	hsa-miR-3155	CLIP-seq
MIRT762766	hsa-miR-3155b	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT1924847	hsa-miR-3163	CLIP-seq
MIRT1924848	hsa-miR-3170	CLIP-seq
MIRT762767	hsa-miR-3194-5p	CLIP-seq
MIRT1924849	hsa-miR-340	CLIP-seq
MIRT1924850	hsa-miR-342-5p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT762707	hsa-miR-3655	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762770	hsa-miR-3667-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT1924851	hsa-miR-3938	CLIP-seq
MIRT762776	hsa-miR-3972	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762716	hsa-miR-4271	CLIP-seq
MIRT1924853	hsa-miR-4328	CLIP-seq
MIRT1924854	hsa-miR-4418	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT762720	hsa-miR-4525	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT1924856	hsa-miR-4651	CLIP-seq
MIRT1924857	hsa-miR-4664-5p	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762784	hsa-miR-4690-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762726	hsa-miR-4723-5p	CLIP-seq
MIRT762727	hsa-miR-4725-3p	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762786	hsa-miR-4793-5p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT1924858	hsa-miR-509-3-5p	CLIP-seq
MIRT1924859	hsa-miR-509-5p	CLIP-seq
MIRT1924860	hsa-miR-511	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT1924862	hsa-miR-608	CLIP-seq
MIRT762745	hsa-miR-625	CLIP-seq
MIRT762791	hsa-miR-626	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762753	hsa-miR-1202	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762693	hsa-miR-1253	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT2166055	hsa-miR-129-3p	CLIP-seq
MIRT2166056	hsa-miR-1304	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT2166057	hsa-miR-2113	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762699	hsa-miR-22	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT2166058	hsa-miR-2276	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT2166059	hsa-miR-297	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT762763	hsa-miR-3120-5p	CLIP-seq
MIRT2166060	hsa-miR-3145-5p	CLIP-seq
MIRT762765	hsa-miR-3155	CLIP-seq
MIRT762766	hsa-miR-3155b	CLIP-seq
MIRT2166061	hsa-miR-3156-5p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT762767	hsa-miR-3194-5p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT762707	hsa-miR-3655	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT2166062	hsa-miR-3924	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762776	hsa-miR-3972	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762716	hsa-miR-4271	CLIP-seq
MIRT2166063	hsa-miR-4276	CLIP-seq
MIRT762719	hsa-miR-4499	CLIP-seq
MIRT2166064	hsa-miR-4504	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT762720	hsa-miR-4525	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT2166065	hsa-miR-4527	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT2166066	hsa-miR-4654	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762726	hsa-miR-4723-5p	CLIP-seq
MIRT762727	hsa-miR-4725-3p	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT2166067	hsa-miR-4769-5p	CLIP-seq
MIRT2166068	hsa-miR-4772-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT2166069	hsa-miR-508-5p	CLIP-seq
MIRT1924860	hsa-miR-511	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT2166070	hsa-miR-526b	CLIP-seq
MIRT2166071	hsa-miR-542-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762745	hsa-miR-625	CLIP-seq
MIRT762791	hsa-miR-626	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT2166072	hsa-miR-758	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT762750	hsa-miR-885-3p	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT2166073	hsa-miR-938	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762692	hsa-miR-1244	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762714	hsa-miR-3973	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762786	hsa-miR-4793-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762737	hsa-miR-518a-5p	CLIP-seq
MIRT762738	hsa-miR-527	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT2468584	hsa-miR-1269	CLIP-seq
MIRT2468585	hsa-miR-1269b	CLIP-seq
MIRT2468586	hsa-miR-127-5p	CLIP-seq
MIRT2468587	hsa-miR-1288	CLIP-seq
MIRT2166055	hsa-miR-129-3p	CLIP-seq
MIRT2468588	hsa-miR-147	CLIP-seq
MIRT2166057	hsa-miR-2113	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT2166058	hsa-miR-2276	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT2166059	hsa-miR-297	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT2468589	hsa-miR-3138	CLIP-seq
MIRT2166060	hsa-miR-3145-5p	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT2166061	hsa-miR-3156-5p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT1924847	hsa-miR-3163	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT2468590	hsa-miR-3185	CLIP-seq
MIRT2468591	hsa-miR-3189-5p	CLIP-seq
MIRT1924849	hsa-miR-340	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT2468592	hsa-miR-3663-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT2468593	hsa-miR-3911	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT2166062	hsa-miR-3924	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT2166063	hsa-miR-4276	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT2468594	hsa-miR-4477a	CLIP-seq
MIRT2166064	hsa-miR-4504	CLIP-seq
MIRT2468595	hsa-miR-4515	CLIP-seq
MIRT2468596	hsa-miR-4517	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT2468597	hsa-miR-4522	CLIP-seq
MIRT2166065	hsa-miR-4527	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT2166066	hsa-miR-4654	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT2468598	hsa-miR-4740-5p	CLIP-seq
MIRT2166067	hsa-miR-4769-5p	CLIP-seq
MIRT2166068	hsa-miR-4772-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT2468599	hsa-miR-4800-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT2166069	hsa-miR-508-5p	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT2166071	hsa-miR-542-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT2468600	hsa-miR-599	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT2468601	hsa-miR-644	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT2166072	hsa-miR-758	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT2166073	hsa-miR-938	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT2468584	hsa-miR-1269	CLIP-seq
MIRT2468585	hsa-miR-1269b	CLIP-seq
MIRT2468586	hsa-miR-127-5p	CLIP-seq
MIRT2468587	hsa-miR-1288	CLIP-seq
MIRT2166055	hsa-miR-129-3p	CLIP-seq
MIRT2468588	hsa-miR-147	CLIP-seq
MIRT2166057	hsa-miR-2113	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT2166058	hsa-miR-2276	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT2166059	hsa-miR-297	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT2468589	hsa-miR-3138	CLIP-seq
MIRT2166060	hsa-miR-3145-5p	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT2166061	hsa-miR-3156-5p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT1924847	hsa-miR-3163	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT2468590	hsa-miR-3185	CLIP-seq
MIRT2468591	hsa-miR-3189-5p	CLIP-seq
MIRT1924849	hsa-miR-340	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT2468592	hsa-miR-3663-5p	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT2468593	hsa-miR-3911	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT2166062	hsa-miR-3924	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT2166063	hsa-miR-4276	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT2468594	hsa-miR-4477a	CLIP-seq
MIRT2166064	hsa-miR-4504	CLIP-seq
MIRT2468595	hsa-miR-4515	CLIP-seq
MIRT2468596	hsa-miR-4517	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT2468597	hsa-miR-4522	CLIP-seq
MIRT2166065	hsa-miR-4527	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT2166066	hsa-miR-4654	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT2468598	hsa-miR-4740-5p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762730	hsa-miR-4764-5p	CLIP-seq
MIRT2166067	hsa-miR-4769-5p	CLIP-seq
MIRT2166068	hsa-miR-4772-3p	CLIP-seq
MIRT762732	hsa-miR-4781-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT2468599	hsa-miR-4800-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT2166069	hsa-miR-508-5p	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT2166071	hsa-miR-542-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT2468600	hsa-miR-599	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT2468601	hsa-miR-644	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT2166072	hsa-miR-758	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT2166073	hsa-miR-938	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
SREBF1	Activation	10777536

Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003824	Function	Catalytic activity	IEA
GO:0003878	Function	ATP citrate synthase activity	IBA
GO:0003878	Function	ATP citrate synthase activity	IDA	1371749, 9116495, 10653665, 19286649
GO:0003878	Function	ATP citrate synthase activity	IEA
GO:0003878	Function	ATP citrate synthase activity	TAS	23932781
GO:0005515	Function	Protein binding	IPI	23932781
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	TAS	1371749
GO:0005576	Component	Extracellular region	TAS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	9116495
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006085	Process	Acetyl-CoA biosynthetic process	IBA
GO:0006085	Process	Acetyl-CoA biosynthetic process	IDA	1371749
GO:0006085	Process	Acetyl-CoA biosynthetic process	IEA
GO:0006085	Process	Acetyl-CoA biosynthetic process	IMP	39881208
GO:0006101	Process	Citrate metabolic process	IDA	1371749
GO:0006101	Process	Citrate metabolic process	IEA
GO:0006107	Process	Oxaloacetate metabolic process	IDA	1371749
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IBA
GO:0006633	Process	Fatty acid biosynthetic process	IDA	10653665, 19286649
GO:0006695	Process	Cholesterol biosynthetic process	TAS	1371749
GO:0008610	Process	Lipid biosynthetic process	IDA	23932781
GO:0015936	Process	Coenzyme A metabolic process	TAS	1371749
GO:0016020	Component	Membrane	HDA	19946888
GO:0016740	Function	Transferase activity	IEA
GO:0035578	Component	Azurophil granule lumen	TAS
GO:0036064	Component	Ciliary basal body	IDA
GO:0046872	Function	Metal ion binding	IEA
GO:0046912	Function	Acyltransferase activity, acyl groups converted into alkyl on transfer	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337, 23533145
GO:0110076	Process	Negative regulation of ferroptosis	IMP	39881208
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

MIM	HGNC	e!Ensembl
108728	115	ENSG00000131473

P53396

Protein name

ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme)

Protein function

Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism. {ECO:0000269|PubMed:10653665, ECO:0000269|PubMed:1371749,

PDB

3MWD , 3MWE , 3PFF , 5TDE , 5TDF , 5TDM , 5TDZ , 5TE1 , 5TEQ , 5TES , 5TET , 6HXH , 6HXK , 6HXL , 6HXM , 6O0H , 6POE , 6POF , 6QFB , 6UI9 , 6UIA , 6UUW , 6UUZ , 6UV5 , 6Z2H , 7LIW , 7LJ9 , 7LLA , 7RIG , 7RKZ , 7RMP , 8G1E , 8G1F , 8G5C , 8G5D

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16114	Citrate_bind	244 → 421	ATP citrate lyase citrate-binding	Domain
PF02629	CoA_binding	494 → 600	CoA binding domain	Domain
PF00549	Ligase_CoA	660 → 785	CoA-ligase	Domain
PF00285	Citrate_synt	883 → 1086	Citrate synthase, C-terminal domain	Domain

Sequence

MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD
QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY
VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI
LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP
PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE
LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA
IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG
HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP
SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK
FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG
IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV
SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG
GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK
EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF
MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH
GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV
NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN
LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK
QGLYRHPWDDISYVLPEHMSM

Sequence length

1101

Interactions

View interactions

	KEGG		Reactome
	Citrate cycle (TCA cycle) Metabolic pathways		ChREBP activates metabolic gene expression Neutrophil degranulation Fatty acyl-CoA biosynthesis

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (12)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CARCINOMA, HEPATOCELLULAR	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGESTIVE HEART FAILURE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEART FAILURE	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Pancreatic adenocarcinoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (106)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	18922930		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Oligodendroglioma	Oligodendroglioma	BEFREE	25277207		★★★★★ ★☆☆☆☆ Found in Text Mining only
Aortic Aneurysm, Abdominal	Aortic Aneurysm	BEFREE	29087237		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	28059952, 28153881, 30586346, 31499095		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	BEFREE	27221641		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Infectious	Infective arthritis	Pubtator	37414769	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	28059952, 28153881, 30586346, 31499095		★★★★★ ★☆☆☆☆ Found in Text Mining only
Behcet Syndrome	Behcet Syndrome	BEFREE	30050389		★★★★★ ★☆☆☆☆ Found in Text Mining only
Behcet Syndrome	Behcet disease	Pubtator	30050389	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	27015560, 28443474		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	26928812, 28443474, 37899460	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	36562384	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	35449157, 38009671	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	25735330, 29271183, 30176945, 34311471, 35227773, 35449157	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	18922930, 25227797, 27664236		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	22266777	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	34505339	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	22266777		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	28059952, 31499095		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular disease	Pubtator	30865797, 32231389	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular disease	Pubtator	39202419	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Oligodendroglioma	Oligodendroglioma	BEFREE	25277207		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	39399493	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Kidney Diseases	Kidney Disease	BEFREE	31150280		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	29654555		★★★★★ ★☆☆☆☆ Found in Text Mining only
Clear-cell metastatic renal cell carcinoma	Renal Carcinoma	BEFREE	29725424, 31777589		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	31511060		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	24132143, 25890184		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	24132143	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	25890184, 33484818, 35177584	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	CTD_human_DG	26670611		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	29725424		★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	26718638, 27221641, 27557479, 28289822, 29331994, 29421350, 29550753, 29778418, 29929979, 30707249, 30762314, 30944945, 31103415, 31169629, 31424112, 31718284 View all (1 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	26367490	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	39202419	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	26367490, 31088900		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dyslipidemias	Dyslipidemias	BEFREE	28059952, 29237473, 30944472, 31499095		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	22266777		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty Liver	BEFREE	22272335, 30944472, 31197036		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty liver	Pubtator	37414769	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty liver	Pubtator	37620891	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Fatty Liver Disease	Fatty Liver	BEFREE	30466110		★★★★★ ★☆☆☆☆ Found in Text Mining only
Gallbladder Neoplasms	Gallbladder neoplasm	Pubtator	37747441	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulosclerosis (disorder)	Glomerulosclerosis	BEFREE	31150280		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	CTD_human_DG	26670611		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Heart Failure, Right-Sided	Heart Failure	CTD_human_DG	26670611		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Leiomyomatosis and Renal Cell Cancer	Hereditary Leiomyomatosis and Renal Cancer	BEFREE	30836850		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypercholesterolemia	Hypercholesterolemia	BEFREE	30922146		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperinsulinism	Hyperinsulinism	BEFREE	26367490		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperlipidemia	Hyperlipidemia	BEFREE	28993031		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	26452058, 35227773	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inclusion Body Myopathy, Sporadic	Inclusion body myopathy	BEFREE	28259850		★★★★★ ★☆☆☆☆ Found in Text Mining only
Juvenile Neuronal Ceroid Lipofuscinosis	Neuronal Ceroid Lipofuscinosis	BEFREE	23524239		★★★★★ ★☆☆☆☆ Found in Text Mining only
Left-Sided Heart Failure	Heart Failure	CTD_human_DG	26670611		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	31077215	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	31077215	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Mast-Cell	Leukemia	BEFREE	30836850		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	31077215		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	CTD_human_DG	21147110		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25735330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Diseases	Liver disease	Pubtator	32054087	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung diseases	Lung Diseases	BEFREE	30343145		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	LHGDN	18922930		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	25227797, 38069382	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	27015560, 28443474		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	18922930, 23932781, 25227797, 27317765, 27664236		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	29466694, 31579071		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	30716442		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	22787121, 23932781, 24310723, 25537655, 26701850, 27664236, 27997879, 28129980, 29970880, 30195238, 31400935, 31830561		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	31511060		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malnutrition	Malnutrition	BEFREE	26210960, 28289822		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	27015560		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mantle cell lymphoma	Mantle Cell Lymphoma	BEFREE	30836850		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	37801083	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Metabolic Diseases	Metabolic Diseases	BEFREE	28993031, 30877197		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Diseases	Metabolic syndrome	Pubtator	37620891	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	33462268	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Failure	Myocardial Infarction	CTD_human_DG	26670611		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	21688263, 22266777, 23932781, 25367309, 25537655, 27317765, 27664236, 27912843		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	23931760, 30466110, 31197036		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	25837797		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	CTD_human_DG	20882379		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
oligodendroglioma	Oligodendroglioma	BEFREE	25277207		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oligodendroglioma	Oligodendroglioma	Pubtator	25277207	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	29929979	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis Knee	Osteoarthritis	Pubtator	29929979	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis, Knee	Knee osteoarthritis	BEFREE	28259850, 29550753, 31404935, 31732650		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	27317765		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	22266777	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	34505339	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Peritonitis	Peritonitis	Pubtator	38009671	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
POLYCYSTIC KIDNEY DISEASE 3 WITH OR WITHOUT POLYCYSTIC LIVER DISEASE	Polycystic Kidney Disease With Or Without Polycystic Liver Disease	BEFREE	31772672		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	20220513, 29466694, 31579071		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	24980815, 27248322	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	29725424		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal fibrosis	Renal fibrosis	BEFREE	28490526, 29415885		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sepsis	Sepsis	Pubtator	37414769	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	31817870		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	32597160	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Steatohepatitis	Fatty Liver	BEFREE	30944472, 31197036		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	30716442		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	36064336	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	38009671	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Synovitis	Synovitis	BEFREE	30406813		★★★★★ ★☆☆☆☆ Found in Text Mining only
Trigeminal Neuralgia	Trigeminal neuralgia	BEFREE	29230177		★★★★★ ★☆☆☆☆ Found in Text Mining only
Well Differentiated Oligodendroglioma	Oligodendroglioma	BEFREE	25277207		★★★★★ ★☆☆☆☆ Found in Text Mining only

ACLY (ATP citrate lyase)