COXFA4 (cytochrome c oxidase associated subunit FA4)

Gene

• Entrez ID: 4697
• Gene name: Cytochrome c oxidase associated subunit FA4
• Gene symbol: COXFA4
• Synonyms (NCBI Gene): CI-9k, CI-MLRQ, MC4DN21, MISTR1, MLRQ, MRCAF1, NDUFA4
• Chromosome: 7
• Chromosome location: 7p21.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021524	hsa-miR-145-5p	Reporter assay;Microarray	21351259
MIRT025792	hsa-miR-7-5p	Microarray	19073608
MIRT031645	hsa-miR-16-5p	Sequencing	20371350
MIRT045020	hsa-miR-186-5p	CLASH	23622248
MIRT037742	hsa-miR-147b	CLASH	23622248
MIRT054098	hsa-miR-210-3p	Luciferase reporter assay	23492775
MIRT054098	hsa-miR-210-3p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23028679
MIRT054212	hsa-miR-147a	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23028679
MIRT037742	hsa-miR-147b	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23028679
MIRT440128	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT440128	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT025792	hsa-miR-7-5p	Western blot	28325285
MIRT025792	hsa-miR-7-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28325285
MIRT025792	hsa-miR-7-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28325285
MIRT025792	hsa-miR-7-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28325285
MIRT025792	hsa-miR-7-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28325285
MIRT025792	hsa-miR-7-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28325285
MIRT025792	hsa-miR-7-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28325285
MIRT1178687	hsa-let-7a	CLIP-seq
MIRT1178688	hsa-let-7b	CLIP-seq
MIRT1178689	hsa-let-7c	CLIP-seq
MIRT1178690	hsa-let-7d	CLIP-seq
MIRT1178691	hsa-let-7e	CLIP-seq
MIRT1178692	hsa-let-7f	CLIP-seq
MIRT1178693	hsa-let-7g	CLIP-seq
MIRT1178694	hsa-let-7i	CLIP-seq
MIRT1178695	hsa-miR-10a	CLIP-seq
MIRT1178696	hsa-miR-10b	CLIP-seq
MIRT1178697	hsa-miR-1231	CLIP-seq
MIRT1178698	hsa-miR-1285	CLIP-seq
MIRT1178699	hsa-miR-1298	CLIP-seq
MIRT1178700	hsa-miR-1299	CLIP-seq
MIRT1178701	hsa-miR-1303	CLIP-seq
MIRT1178702	hsa-miR-1323	CLIP-seq
MIRT1178703	hsa-miR-1343	CLIP-seq
MIRT1178704	hsa-miR-142-3p	CLIP-seq
MIRT1178705	hsa-miR-1827	CLIP-seq
MIRT1178706	hsa-miR-205	CLIP-seq
MIRT1178707	hsa-miR-2054	CLIP-seq
MIRT1178708	hsa-miR-210	CLIP-seq
MIRT1178709	hsa-miR-216a	CLIP-seq
MIRT1178710	hsa-miR-216b	CLIP-seq
MIRT1178711	hsa-miR-29a	CLIP-seq
MIRT1178712	hsa-miR-29b	CLIP-seq
MIRT1178713	hsa-miR-29c	CLIP-seq
MIRT1178714	hsa-miR-3074-5p	CLIP-seq
MIRT1178715	hsa-miR-3125	CLIP-seq
MIRT1178716	hsa-miR-3137	CLIP-seq
MIRT1178717	hsa-miR-3140-3p	CLIP-seq
MIRT1178718	hsa-miR-3148	CLIP-seq
MIRT1178719	hsa-miR-3150b-3p	CLIP-seq
MIRT1178720	hsa-miR-3153	CLIP-seq
MIRT1178721	hsa-miR-3187-5p	CLIP-seq
MIRT1178722	hsa-miR-323b-3p	CLIP-seq
MIRT1178723	hsa-miR-339-5p	CLIP-seq
MIRT1178724	hsa-miR-3606	CLIP-seq
MIRT1178725	hsa-miR-3647-3p	CLIP-seq
MIRT1178726	hsa-miR-3916	CLIP-seq
MIRT1178727	hsa-miR-3927	CLIP-seq
MIRT1178728	hsa-miR-3940-3p	CLIP-seq
MIRT1178729	hsa-miR-3942-3p	CLIP-seq
MIRT1178730	hsa-miR-3976	CLIP-seq
MIRT1178731	hsa-miR-4288	CLIP-seq
MIRT1178732	hsa-miR-4289	CLIP-seq
MIRT1178733	hsa-miR-4421	CLIP-seq
MIRT1178734	hsa-miR-4422	CLIP-seq
MIRT1178735	hsa-miR-4451	CLIP-seq
MIRT1178736	hsa-miR-4455	CLIP-seq
MIRT1178737	hsa-miR-4458	CLIP-seq
MIRT1178738	hsa-miR-4459	CLIP-seq
MIRT1178739	hsa-miR-4470	CLIP-seq
MIRT1178740	hsa-miR-4474-3p	CLIP-seq
MIRT1178741	hsa-miR-4500	CLIP-seq
MIRT1178742	hsa-miR-4509	CLIP-seq
MIRT1178743	hsa-miR-4661-5p	CLIP-seq
MIRT1178744	hsa-miR-4722-5p	CLIP-seq
MIRT1178745	hsa-miR-4744	CLIP-seq
MIRT1178746	hsa-miR-4764-5p	CLIP-seq
MIRT1178747	hsa-miR-4782-5p	CLIP-seq
MIRT1178748	hsa-miR-4784	CLIP-seq
MIRT1178749	hsa-miR-4786-5p	CLIP-seq
MIRT1178750	hsa-miR-4799-5p	CLIP-seq
MIRT1178751	hsa-miR-4802-3p	CLIP-seq
MIRT1178752	hsa-miR-485-5p	CLIP-seq
MIRT1178753	hsa-miR-494	CLIP-seq
MIRT1178754	hsa-miR-503	CLIP-seq
MIRT1178755	hsa-miR-511	CLIP-seq
MIRT1178756	hsa-miR-515-5p	CLIP-seq
MIRT1178757	hsa-miR-516b	CLIP-seq
MIRT1178758	hsa-miR-520f	CLIP-seq
MIRT1178759	hsa-miR-539	CLIP-seq
MIRT1178760	hsa-miR-548g	CLIP-seq
MIRT1178761	hsa-miR-548o	CLIP-seq
MIRT1178762	hsa-miR-586	CLIP-seq
MIRT1178763	hsa-miR-593	CLIP-seq
MIRT1178764	hsa-miR-609	CLIP-seq
MIRT1178765	hsa-miR-612	CLIP-seq
MIRT1178766	hsa-miR-632	CLIP-seq
MIRT1178767	hsa-miR-646	CLIP-seq
MIRT1178768	hsa-miR-661	CLIP-seq
MIRT1178769	hsa-miR-7	CLIP-seq
MIRT1178770	hsa-miR-767-5p	CLIP-seq
MIRT1178771	hsa-miR-769-5p	CLIP-seq
MIRT1178772	hsa-miR-875-3p	CLIP-seq
MIRT1178773	hsa-miR-877	CLIP-seq
MIRT1178774	hsa-miR-935	CLIP-seq
MIRT1178775	hsa-miR-940	CLIP-seq
MIRT1178776	hsa-miR-98	CLIP-seq
MIRT1178700	hsa-miR-1299	CLIP-seq
MIRT1178708	hsa-miR-210	CLIP-seq
MIRT1178718	hsa-miR-3148	CLIP-seq
MIRT1178725	hsa-miR-3647-3p	CLIP-seq
MIRT1178740	hsa-miR-4474-3p	CLIP-seq
MIRT1178746	hsa-miR-4764-5p	CLIP-seq
MIRT1178747	hsa-miR-4782-5p	CLIP-seq
MIRT1178757	hsa-miR-516b	CLIP-seq
MIRT1178768	hsa-miR-661	CLIP-seq
MIRT1178769	hsa-miR-7	CLIP-seq
MIRT1178772	hsa-miR-875-3p	CLIP-seq
MIRT1178695	hsa-miR-10a	CLIP-seq
MIRT1178696	hsa-miR-10b	CLIP-seq
MIRT1178698	hsa-miR-1285	CLIP-seq
MIRT1178699	hsa-miR-1298	CLIP-seq
MIRT1178700	hsa-miR-1299	CLIP-seq
MIRT1178706	hsa-miR-205	CLIP-seq
MIRT1178708	hsa-miR-210	CLIP-seq
MIRT2051725	hsa-miR-3130-3p	CLIP-seq
MIRT1178718	hsa-miR-3148	CLIP-seq
MIRT1178719	hsa-miR-3150b-3p	CLIP-seq
MIRT1178721	hsa-miR-3187-5p	CLIP-seq
MIRT1178723	hsa-miR-339-5p	CLIP-seq
MIRT1178724	hsa-miR-3606	CLIP-seq
MIRT1178725	hsa-miR-3647-3p	CLIP-seq
MIRT2051726	hsa-miR-3672	CLIP-seq
MIRT2051727	hsa-miR-421	CLIP-seq
MIRT1178733	hsa-miR-4421	CLIP-seq
MIRT1178734	hsa-miR-4422	CLIP-seq
MIRT1178739	hsa-miR-4470	CLIP-seq
MIRT1178740	hsa-miR-4474-3p	CLIP-seq
MIRT1178742	hsa-miR-4509	CLIP-seq
MIRT2051728	hsa-miR-4709-5p	CLIP-seq
MIRT1178745	hsa-miR-4744	CLIP-seq
MIRT1178746	hsa-miR-4764-5p	CLIP-seq
MIRT1178747	hsa-miR-4782-5p	CLIP-seq
MIRT1178748	hsa-miR-4784	CLIP-seq
MIRT1178749	hsa-miR-4786-5p	CLIP-seq
MIRT1178750	hsa-miR-4799-5p	CLIP-seq
MIRT1178753	hsa-miR-494	CLIP-seq
MIRT1178754	hsa-miR-503	CLIP-seq
MIRT1178757	hsa-miR-516b	CLIP-seq
MIRT2051729	hsa-miR-570	CLIP-seq
MIRT1178763	hsa-miR-593	CLIP-seq
MIRT1178765	hsa-miR-612	CLIP-seq
MIRT1178768	hsa-miR-661	CLIP-seq
MIRT1178769	hsa-miR-7	CLIP-seq
MIRT1178770	hsa-miR-767-5p	CLIP-seq
MIRT1178771	hsa-miR-769-5p	CLIP-seq
MIRT1178772	hsa-miR-875-3p	CLIP-seq
MIRT1178687	hsa-let-7a	CLIP-seq
MIRT1178688	hsa-let-7b	CLIP-seq
MIRT1178689	hsa-let-7c	CLIP-seq
MIRT1178690	hsa-let-7d	CLIP-seq
MIRT1178691	hsa-let-7e	CLIP-seq
MIRT1178692	hsa-let-7f	CLIP-seq
MIRT1178693	hsa-let-7g	CLIP-seq
MIRT1178694	hsa-let-7i	CLIP-seq
MIRT1178695	hsa-miR-10a	CLIP-seq
MIRT1178696	hsa-miR-10b	CLIP-seq
MIRT2280773	hsa-miR-1208	CLIP-seq
MIRT1178697	hsa-miR-1231	CLIP-seq
MIRT2280774	hsa-miR-1262	CLIP-seq
MIRT1178698	hsa-miR-1285	CLIP-seq
MIRT1178699	hsa-miR-1298	CLIP-seq
MIRT1178700	hsa-miR-1299	CLIP-seq
MIRT1178701	hsa-miR-1303	CLIP-seq
MIRT1178703	hsa-miR-1343	CLIP-seq
MIRT1178704	hsa-miR-142-3p	CLIP-seq
MIRT1178706	hsa-miR-205	CLIP-seq
MIRT1178707	hsa-miR-2054	CLIP-seq
MIRT1178708	hsa-miR-210	CLIP-seq
MIRT2280775	hsa-miR-2114	CLIP-seq
MIRT1178709	hsa-miR-216a	CLIP-seq
MIRT1178710	hsa-miR-216b	CLIP-seq
MIRT2280776	hsa-miR-3065-3p	CLIP-seq
MIRT1178714	hsa-miR-3074-5p	CLIP-seq
MIRT1178715	hsa-miR-3125	CLIP-seq
MIRT1178716	hsa-miR-3137	CLIP-seq
MIRT1178717	hsa-miR-3140-3p	CLIP-seq
MIRT1178718	hsa-miR-3148	CLIP-seq
MIRT1178719	hsa-miR-3150b-3p	CLIP-seq
MIRT1178721	hsa-miR-3187-5p	CLIP-seq
MIRT2280777	hsa-miR-3192	CLIP-seq
MIRT1178722	hsa-miR-323b-3p	CLIP-seq
MIRT2280778	hsa-miR-335	CLIP-seq
MIRT2280779	hsa-miR-338-5p	CLIP-seq
MIRT1178723	hsa-miR-339-5p	CLIP-seq
MIRT1178724	hsa-miR-3606	CLIP-seq
MIRT2280780	hsa-miR-3620	CLIP-seq
MIRT1178725	hsa-miR-3647-3p	CLIP-seq
MIRT2280781	hsa-miR-3670	CLIP-seq
MIRT2051726	hsa-miR-3672	CLIP-seq
MIRT2280782	hsa-miR-3677-5p	CLIP-seq
MIRT2280783	hsa-miR-3689a-3p	CLIP-seq
MIRT2280784	hsa-miR-3689c	CLIP-seq
MIRT1178726	hsa-miR-3916	CLIP-seq
MIRT1178727	hsa-miR-3927	CLIP-seq
MIRT2280785	hsa-miR-3929	CLIP-seq
MIRT1178728	hsa-miR-3940-3p	CLIP-seq
MIRT2280786	hsa-miR-3941	CLIP-seq
MIRT1178729	hsa-miR-3942-3p	CLIP-seq
MIRT1178730	hsa-miR-3976	CLIP-seq
MIRT2051727	hsa-miR-421	CLIP-seq
MIRT2280787	hsa-miR-4257	CLIP-seq
MIRT2280788	hsa-miR-4278	CLIP-seq
MIRT1178731	hsa-miR-4288	CLIP-seq
MIRT1178732	hsa-miR-4289	CLIP-seq
MIRT2280789	hsa-miR-4292	CLIP-seq
MIRT2280790	hsa-miR-4419b	CLIP-seq
MIRT1178733	hsa-miR-4421	CLIP-seq
MIRT1178734	hsa-miR-4422	CLIP-seq
MIRT2280791	hsa-miR-4449	CLIP-seq
MIRT1178735	hsa-miR-4451	CLIP-seq
MIRT1178737	hsa-miR-4458	CLIP-seq
MIRT1178739	hsa-miR-4470	CLIP-seq
MIRT1178740	hsa-miR-4474-3p	CLIP-seq
MIRT2280792	hsa-miR-4478	CLIP-seq
MIRT1178741	hsa-miR-4500	CLIP-seq
MIRT1178742	hsa-miR-4509	CLIP-seq
MIRT2280793	hsa-miR-452	CLIP-seq
MIRT2280794	hsa-miR-466	CLIP-seq
MIRT2280795	hsa-miR-4672	CLIP-seq
MIRT2280796	hsa-miR-4676-3p	CLIP-seq
MIRT2280797	hsa-miR-4688	CLIP-seq
MIRT2280798	hsa-miR-4689	CLIP-seq
MIRT2280799	hsa-miR-4701-3p	CLIP-seq
MIRT2051728	hsa-miR-4709-5p	CLIP-seq
MIRT2280800	hsa-miR-4728-5p	CLIP-seq
MIRT2280801	hsa-miR-4731-3p	CLIP-seq
MIRT1178745	hsa-miR-4744	CLIP-seq
MIRT1178746	hsa-miR-4764-5p	CLIP-seq
MIRT1178747	hsa-miR-4782-5p	CLIP-seq
MIRT1178748	hsa-miR-4784	CLIP-seq
MIRT1178749	hsa-miR-4786-5p	CLIP-seq
MIRT2280802	hsa-miR-4789-3p	CLIP-seq
MIRT2280803	hsa-miR-4793-3p	CLIP-seq
MIRT1178750	hsa-miR-4799-5p	CLIP-seq
MIRT2280804	hsa-miR-4801	CLIP-seq
MIRT1178752	hsa-miR-485-5p	CLIP-seq
MIRT1178753	hsa-miR-494	CLIP-seq
MIRT1178754	hsa-miR-503	CLIP-seq
MIRT2280805	hsa-miR-505	CLIP-seq
MIRT2280806	hsa-miR-508-5p	CLIP-seq
MIRT1178755	hsa-miR-511	CLIP-seq
MIRT1178756	hsa-miR-515-5p	CLIP-seq
MIRT1178757	hsa-miR-516b	CLIP-seq
MIRT1178758	hsa-miR-520f	CLIP-seq
MIRT1178759	hsa-miR-539	CLIP-seq
MIRT2280807	hsa-miR-542-3p	CLIP-seq
MIRT1178762	hsa-miR-586	CLIP-seq
MIRT2280808	hsa-miR-590-3p	CLIP-seq
MIRT1178763	hsa-miR-593	CLIP-seq
MIRT1178765	hsa-miR-612	CLIP-seq
MIRT1178766	hsa-miR-632	CLIP-seq
MIRT2280809	hsa-miR-642b	CLIP-seq
MIRT1178768	hsa-miR-661	CLIP-seq
MIRT1178769	hsa-miR-7	CLIP-seq
MIRT2280810	hsa-miR-766	CLIP-seq
MIRT1178771	hsa-miR-769-5p	CLIP-seq
MIRT1178772	hsa-miR-875-3p	CLIP-seq
MIRT1178773	hsa-miR-877	CLIP-seq
MIRT1178774	hsa-miR-935	CLIP-seq
MIRT1178776	hsa-miR-98	CLIP-seq
MIRT1178773	hsa-miR-877	CLIP-seq
MIRT1178695	hsa-miR-10a	CLIP-seq
MIRT1178696	hsa-miR-10b	CLIP-seq
MIRT1178698	hsa-miR-1285	CLIP-seq
MIRT1178721	hsa-miR-3187-5p	CLIP-seq
MIRT1178723	hsa-miR-339-5p	CLIP-seq
MIRT1178733	hsa-miR-4421	CLIP-seq
MIRT1178739	hsa-miR-4470	CLIP-seq
MIRT1178742	hsa-miR-4509	CLIP-seq
MIRT1178745	hsa-miR-4744	CLIP-seq
MIRT1178749	hsa-miR-4786-5p	CLIP-seq
MIRT2455027	hsa-miR-561	CLIP-seq
MIRT1178763	hsa-miR-593	CLIP-seq
MIRT1178765	hsa-miR-612	CLIP-seq
MIRT1178768	hsa-miR-661	CLIP-seq
MIRT1178771	hsa-miR-769-5p	CLIP-seq
MIRT1178695	hsa-miR-10a	CLIP-seq
MIRT1178696	hsa-miR-10b	CLIP-seq
MIRT1178698	hsa-miR-1285	CLIP-seq
MIRT1178699	hsa-miR-1298	CLIP-seq
MIRT1178700	hsa-miR-1299	CLIP-seq
MIRT1178701	hsa-miR-1303	CLIP-seq
MIRT1178702	hsa-miR-1323	CLIP-seq
MIRT1178703	hsa-miR-1343	CLIP-seq
MIRT1178706	hsa-miR-205	CLIP-seq
MIRT1178707	hsa-miR-2054	CLIP-seq
MIRT1178708	hsa-miR-210	CLIP-seq
MIRT1178709	hsa-miR-216a	CLIP-seq
MIRT1178710	hsa-miR-216b	CLIP-seq
MIRT2280776	hsa-miR-3065-3p	CLIP-seq
MIRT1178714	hsa-miR-3074-5p	CLIP-seq
MIRT1178715	hsa-miR-3125	CLIP-seq
MIRT1178718	hsa-miR-3148	CLIP-seq
MIRT1178719	hsa-miR-3150b-3p	CLIP-seq
MIRT1178721	hsa-miR-3187-5p	CLIP-seq
MIRT2280777	hsa-miR-3192	CLIP-seq
MIRT1178722	hsa-miR-323b-3p	CLIP-seq
MIRT2280779	hsa-miR-338-5p	CLIP-seq
MIRT1178723	hsa-miR-339-5p	CLIP-seq
MIRT2280780	hsa-miR-3620	CLIP-seq
MIRT1178725	hsa-miR-3647-3p	CLIP-seq
MIRT2280783	hsa-miR-3689a-3p	CLIP-seq
MIRT2280784	hsa-miR-3689c	CLIP-seq
MIRT1178726	hsa-miR-3916	CLIP-seq
MIRT2280785	hsa-miR-3929	CLIP-seq
MIRT1178730	hsa-miR-3976	CLIP-seq
MIRT1178732	hsa-miR-4289	CLIP-seq
MIRT2280789	hsa-miR-4292	CLIP-seq
MIRT2280790	hsa-miR-4419b	CLIP-seq
MIRT1178733	hsa-miR-4421	CLIP-seq
MIRT1178734	hsa-miR-4422	CLIP-seq
MIRT1178736	hsa-miR-4455	CLIP-seq
MIRT1178739	hsa-miR-4470	CLIP-seq
MIRT1178740	hsa-miR-4474-3p	CLIP-seq
MIRT2280792	hsa-miR-4478	CLIP-seq
MIRT1178742	hsa-miR-4509	CLIP-seq
MIRT2280800	hsa-miR-4728-5p	CLIP-seq
MIRT1178745	hsa-miR-4744	CLIP-seq
MIRT1178746	hsa-miR-4764-5p	CLIP-seq
MIRT1178747	hsa-miR-4782-5p	CLIP-seq
MIRT1178748	hsa-miR-4784	CLIP-seq
MIRT1178749	hsa-miR-4786-5p	CLIP-seq
MIRT1178750	hsa-miR-4799-5p	CLIP-seq
MIRT1178751	hsa-miR-4802-3p	CLIP-seq
MIRT1178752	hsa-miR-485-5p	CLIP-seq
MIRT1178754	hsa-miR-503	CLIP-seq
MIRT1178756	hsa-miR-515-5p	CLIP-seq
MIRT1178757	hsa-miR-516b	CLIP-seq
MIRT1178759	hsa-miR-539	CLIP-seq
MIRT1178761	hsa-miR-548o	CLIP-seq
MIRT1178762	hsa-miR-586	CLIP-seq
MIRT1178763	hsa-miR-593	CLIP-seq
MIRT1178764	hsa-miR-609	CLIP-seq
MIRT1178765	hsa-miR-612	CLIP-seq
MIRT1178768	hsa-miR-661	CLIP-seq
MIRT1178769	hsa-miR-7	CLIP-seq
MIRT1178771	hsa-miR-769-5p	CLIP-seq
MIRT1178772	hsa-miR-875-3p	CLIP-seq
MIRT1178773	hsa-miR-877	CLIP-seq
MIRT1178695	hsa-miR-10a	CLIP-seq
MIRT1178696	hsa-miR-10b	CLIP-seq
MIRT1178698	hsa-miR-1285	CLIP-seq
MIRT1178699	hsa-miR-1298	CLIP-seq
MIRT1178700	hsa-miR-1299	CLIP-seq
MIRT1178701	hsa-miR-1303	CLIP-seq
MIRT1178703	hsa-miR-1343	CLIP-seq
MIRT1178706	hsa-miR-205	CLIP-seq
MIRT1178707	hsa-miR-2054	CLIP-seq
MIRT1178708	hsa-miR-210	CLIP-seq
MIRT1178709	hsa-miR-216a	CLIP-seq
MIRT1178710	hsa-miR-216b	CLIP-seq
MIRT2280776	hsa-miR-3065-3p	CLIP-seq
MIRT1178714	hsa-miR-3074-5p	CLIP-seq
MIRT1178715	hsa-miR-3125	CLIP-seq
MIRT1178718	hsa-miR-3148	CLIP-seq
MIRT1178719	hsa-miR-3150b-3p	CLIP-seq
MIRT1178721	hsa-miR-3187-5p	CLIP-seq
MIRT2280777	hsa-miR-3192	CLIP-seq
MIRT1178722	hsa-miR-323b-3p	CLIP-seq
MIRT2280779	hsa-miR-338-5p	CLIP-seq
MIRT1178723	hsa-miR-339-5p	CLIP-seq
MIRT2280780	hsa-miR-3620	CLIP-seq
MIRT1178725	hsa-miR-3647-3p	CLIP-seq
MIRT2280783	hsa-miR-3689a-3p	CLIP-seq
MIRT2280784	hsa-miR-3689c	CLIP-seq
MIRT1178726	hsa-miR-3916	CLIP-seq
MIRT2280785	hsa-miR-3929	CLIP-seq
MIRT1178730	hsa-miR-3976	CLIP-seq
MIRT1178732	hsa-miR-4289	CLIP-seq
MIRT2280789	hsa-miR-4292	CLIP-seq
MIRT2280790	hsa-miR-4419b	CLIP-seq
MIRT1178733	hsa-miR-4421	CLIP-seq
MIRT1178734	hsa-miR-4422	CLIP-seq
MIRT1178739	hsa-miR-4470	CLIP-seq
MIRT1178740	hsa-miR-4474-3p	CLIP-seq
MIRT2280792	hsa-miR-4478	CLIP-seq
MIRT1178742	hsa-miR-4509	CLIP-seq
MIRT2280800	hsa-miR-4728-5p	CLIP-seq
MIRT1178745	hsa-miR-4744	CLIP-seq
MIRT1178746	hsa-miR-4764-5p	CLIP-seq
MIRT1178747	hsa-miR-4782-5p	CLIP-seq
MIRT1178748	hsa-miR-4784	CLIP-seq
MIRT1178749	hsa-miR-4786-5p	CLIP-seq
MIRT1178750	hsa-miR-4799-5p	CLIP-seq
MIRT1178752	hsa-miR-485-5p	CLIP-seq
MIRT1178754	hsa-miR-503	CLIP-seq
MIRT1178756	hsa-miR-515-5p	CLIP-seq
MIRT1178757	hsa-miR-516b	CLIP-seq
MIRT1178759	hsa-miR-539	CLIP-seq
MIRT1178762	hsa-miR-586	CLIP-seq
MIRT1178763	hsa-miR-593	CLIP-seq
MIRT1178765	hsa-miR-612	CLIP-seq
MIRT1178768	hsa-miR-661	CLIP-seq
MIRT1178769	hsa-miR-7	CLIP-seq
MIRT1178771	hsa-miR-769-5p	CLIP-seq
MIRT1178772	hsa-miR-875-3p	CLIP-seq
MIRT1178773	hsa-miR-877	CLIP-seq
MIRT1178774	hsa-miR-935	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19822128, 31536960, 32814053
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	16729965
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0006120	Process	Mitochondrial electron transport, NADH to ubiquinone	NAS	9878551
GO:0006123	Process	Mitochondrial electron transport, cytochrome c to oxygen	NAS	30030519
GO:0008137	Function	NADH dehydrogenase (ubiquinone) activity	NAS	9878551
GO:0008137	Function	NADH dehydrogenase (ubiquinone) activity	TAS	9352085
GO:0016020	Component	Membrane	IEA
GO:0031966	Component	Mitochondrial membrane	IDA	30030519
GO:0044877	Function	Protein-containing complex binding	IDA	23209302
GO:0045271	Component	Respiratory chain complex I	IEA
GO:0045277	Component	Respiratory chain complex IV	IBA
GO:0045277	Component	Respiratory chain complex IV	IDA	22902835
GO:0045277	Component	Respiratory chain complex IV	IEA
GO:0045333	Process	Cellular respiration	NAS	30030519
GO:1902600	Process	Proton transmembrane transport	IEA

Other IDs

• MIM: 603833
• HGNC: 7687
• e!Ensembl: ENSG00000189043

Protein

• UniProt ID: O00483
• Protein name: Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit)
• Protein function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiqu
• PDB: 5Z62
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06522	B12D	11 → 78	NADH-ubiquinone reductase complex 1 MLRQ subunit	Family

• Sequence:

  MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPND
  QYKFYSVNVDYSKLKKERPDF

• Sequence length: 81

Pathways

KEGG:

Oxidative phosphorylation
Metabolic pathways
Thermogenesis
Retrograde endocannabinoid signaling
Non-alcoholic fatty liver disease
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy

Reactome:

TP53 Regulates Metabolic Genes
Respiratory electron transport

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Mitochondrial complex IV deficiency, nuclear type 21	Pathogenic; Likely pathogenic	rs2534043245, rs552689119, rs1781236368	RCV003152864 RCV004595202 RCV001255196	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
LEIGH SYNDROME	—	ClinGen	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LEIGH SYNDROME WITH LEUKODYSTROPHY	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX IV DEFICIENCY, NUCLEAR TYPE 1	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer Disease	Alzheimer disease	Pubtator	28578378, 30691479	Associate	★☆☆☆☆ Found in Text Mining only
Anemia	Anemia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	Pubtator	23253088	Associate	★☆☆☆☆ Found in Text Mining only
Blepharoptosis	Ptosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	11720477	Associate	★☆☆☆☆ Found in Text Mining only
Cerebellar Diseases	Cerebellar Diseases	BEFREE	22617776		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	30348529		★☆☆☆☆ Found in Text Mining only
Cytochrome c Oxidase Deficiency	Cytochrome c oxidase deficiency	Pubtator	23746447	Associate	★☆☆☆☆ Found in Text Mining only
Cytochrome-c Oxidase Deficiency	Cytochrome-C Oxidase Deficiency	GENOMICS_ENGLAND_DG	29636225		★☆☆☆☆ Found in Text Mining only
Dandy-Walker Syndrome	Dandy-Walker Syndrome	BEFREE	22617776		★☆☆☆☆ Found in Text Mining only
Dysarthria	Dysarthria	HPO_DG			★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypertrichosis	HYPERTRICHOSIS	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypertrophic Cardiomyopathy	Hypertrophic cardiomyopathy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Language Development Disorders	Language development disorders	Pubtator	23253088	Associate	★☆☆☆☆ Found in Text Mining only
Leigh syndrome with leukodystrophy	Leigh Syndrome With Leukodystrophy	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Leukodystrophy	Leukodystrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Mood swings	Mood swings	HPO_DG			★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	11720477		★☆☆☆☆ Found in Text Mining only
Nystagmus	Nystagmus	HPO_DG			★☆☆☆☆ Found in Text Mining only
Optic Atrophy	Optic Atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Peripheral Nervous System Diseases	Nervous System Diseases	HPO_DG			★☆☆☆☆ Found in Text Mining only
Progressive cerebellar ataxia	Cerebellar Ataxia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Ptosis	Ptosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Retinitis Pigmentosa	Retinitis Pigmentosa	HPO_DG			★☆☆☆☆ Found in Text Mining only
Severe intellectual disability	Mental retardation	HPO_DG			★☆☆☆☆ Found in Text Mining only
Speech Delay	Speech Delay	BEFREE	23253088		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	30238562, 35977935	Associate	★☆☆☆☆ Found in Text Mining only
Strabismus	Strabismus	HPO_DG			★☆☆☆☆ Found in Text Mining only
Ventricular Septal Defects	Ventricular septal defect	HPO_DG			★☆☆☆☆ Found in Text Mining only