RFPL4B (ret finger protein like 4B)

Gene

• Entrez ID: 442247
• Gene name: Ret finger protein like 4B
• Gene symbol: RFPL4B
• Synonyms (NCBI Gene): RNF211
• Chromosome: 6
• Chromosome location: 6q21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1301950	hsa-miR-140-3p	CLIP-seq
MIRT1301951	hsa-miR-3136-5p	CLIP-seq
MIRT1301952	hsa-miR-4439	CLIP-seq
MIRT1301953	hsa-miR-4474-3p	CLIP-seq
MIRT1301954	hsa-miR-4513	CLIP-seq
MIRT1301955	hsa-miR-4687-3p	CLIP-seq
MIRT1301956	hsa-miR-607	CLIP-seq
MIRT1301957	hsa-miR-943	CLIP-seq
MIRT2089599	hsa-miR-3675-3p	CLIP-seq
MIRT2089600	hsa-miR-4325	CLIP-seq
MIRT2089601	hsa-miR-507	CLIP-seq
MIRT2089602	hsa-miR-557	CLIP-seq
MIRT2089599	hsa-miR-3675-3p	CLIP-seq
MIRT2089600	hsa-miR-4325	CLIP-seq
MIRT2089601	hsa-miR-507	CLIP-seq
MIRT2089602	hsa-miR-557	CLIP-seq
MIRT2089599	hsa-miR-3675-3p	CLIP-seq
MIRT2089600	hsa-miR-4325	CLIP-seq
MIRT2089601	hsa-miR-507	CLIP-seq
MIRT2089602	hsa-miR-557	CLIP-seq
MIRT2610892	hsa-miR-127-5p	CLIP-seq
MIRT2610893	hsa-miR-139-5p	CLIP-seq
MIRT2610894	hsa-miR-548a-3p	CLIP-seq
MIRT2610895	hsa-miR-548e	CLIP-seq
MIRT2610896	hsa-miR-548f	CLIP-seq
MIRT2610897	hsa-miR-600	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010468	Process	Regulation of gene expression	IBA
GO:0045087	Process	Innate immune response	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6ZWI9
• Protein name: Ret finger protein-like 4B (RING finger protein 211)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15227	zf-C3HC4_4	11 → 52		Domain
  PF00622	SPRY	145 → 261	SPRY domain	Family

• Sequence:

  MAKRLQAELSCPVCLDFFSCSISLSCTHVFCFDCIQRYILENHDFRAMCPLCRDVVKVPA
  LEEWQVSVLTLMTKQHNSRLEQSLHVREELRHFREDVTLDAATASSLLVFSNDLRSAQCK
  KIHHDLTKDPRLACVLGTPCFSSGQHYWEVEVGEVKSWSLGVCKEPADRKSNDLFPEHGF
  WISMKAGAIHANTHLERIPASPRLRRVGIFLDADLEEIQFFDVDNNVLIYTHDGFFSLEL
  LCPFFCLELLGEGESGNVLTICP

• Sequence length: 263

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OLIGODENDROGLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations