TMEM151B (transmembrane protein 151B)

Gene

• Entrez ID: 441151
• Gene name: Transmembrane protein 151B
• Gene symbol: TMEM151B
• Synonyms (NCBI Gene): C6orf137, TMEM193, bA444E17.5
• Chromosome: 6
• Chromosome location: 6p21.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT720963	hsa-miR-6865-3p	HITS-CLIP	19536157
MIRT720962	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT720961	hsa-miR-301a-5p	HITS-CLIP	19536157
MIRT720960	hsa-miR-301b-5p	HITS-CLIP	19536157
MIRT720959	hsa-miR-6730-3p	HITS-CLIP	19536157
MIRT720958	hsa-miR-3660	HITS-CLIP	19536157
MIRT720957	hsa-miR-4526	HITS-CLIP	19536157
MIRT720956	hsa-miR-6719-3p	HITS-CLIP	19536157
MIRT720955	hsa-miR-6889-3p	HITS-CLIP	19536157
MIRT720954	hsa-miR-5008-3p	HITS-CLIP	19536157
MIRT720953	hsa-miR-6737-3p	HITS-CLIP	19536157
MIRT720952	hsa-miR-7157-3p	HITS-CLIP	19536157
MIRT720951	hsa-miR-4645-3p	HITS-CLIP	19536157
MIRT720950	hsa-miR-1271-3p	HITS-CLIP	19536157
MIRT720949	hsa-miR-550a-3-5p	HITS-CLIP	19536157
MIRT720948	hsa-miR-550a-5p	HITS-CLIP	19536157
MIRT720947	hsa-miR-550b-2-5p	HITS-CLIP	19536157
MIRT708875	hsa-miR-211-3p	HITS-CLIP	19536157
MIRT708874	hsa-miR-7113-5p	HITS-CLIP	19536157
MIRT708873	hsa-miR-4685-5p	HITS-CLIP	19536157
MIRT708872	hsa-miR-6837-5p	HITS-CLIP	19536157
MIRT708871	hsa-miR-6734-3p	HITS-CLIP	19536157
MIRT708870	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT708869	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT708868	hsa-miR-3925-3p	HITS-CLIP	19536157
MIRT708867	hsa-miR-572	HITS-CLIP	19536157
MIRT643326	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT643325	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT643324	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT643323	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT643322	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT643321	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT643320	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT643319	hsa-miR-6752-3p	HITS-CLIP	23824327
MIRT643318	hsa-miR-3183	HITS-CLIP	23824327
MIRT643317	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT643316	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT643315	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT643314	hsa-miR-4469	HITS-CLIP	23824327
MIRT643313	hsa-miR-517-5p	HITS-CLIP	23824327
MIRT643312	hsa-miR-1251-5p	HITS-CLIP	23824327
MIRT643311	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT643310	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT643309	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT643308	hsa-miR-2682-3p	HITS-CLIP	23824327
MIRT643307	hsa-miR-6781-3p	HITS-CLIP	23824327
MIRT643306	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT643305	hsa-miR-1287-3p	HITS-CLIP	23824327
MIRT643304	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT503596	hsa-miR-483-3p	PAR-CLIP	23446348
MIRT503594	hsa-miR-1273g-3p	PAR-CLIP	23446348
MIRT503593	hsa-miR-4286	PAR-CLIP	23446348
MIRT503592	hsa-miR-6887-3p	PAR-CLIP	23446348
MIRT503591	hsa-miR-6795-3p	PAR-CLIP	23446348
MIRT503590	hsa-miR-6794-3p	PAR-CLIP	23446348
MIRT503589	hsa-miR-6826-3p	PAR-CLIP	23446348
MIRT503596	hsa-miR-483-3p	PAR-CLIP	23446348
MIRT503595	hsa-miR-1910-5p	PAR-CLIP	23446348
MIRT503594	hsa-miR-1273g-3p	PAR-CLIP	23446348
MIRT503593	hsa-miR-4286	PAR-CLIP	23446348
MIRT503592	hsa-miR-6887-3p	PAR-CLIP	23446348
MIRT503591	hsa-miR-6795-3p	PAR-CLIP	23446348
MIRT503590	hsa-miR-6794-3p	PAR-CLIP	23446348
MIRT503589	hsa-miR-6826-3p	PAR-CLIP	23446348
MIRT503588	hsa-miR-4691-5p	PAR-CLIP	23446348
MIRT503587	hsa-miR-6792-3p	PAR-CLIP	23446348
MIRT720963	hsa-miR-6865-3p	HITS-CLIP	19536157
MIRT720962	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT720961	hsa-miR-301a-5p	HITS-CLIP	19536157
MIRT720960	hsa-miR-301b-5p	HITS-CLIP	19536157
MIRT720959	hsa-miR-6730-3p	HITS-CLIP	19536157
MIRT720958	hsa-miR-3660	HITS-CLIP	19536157
MIRT720957	hsa-miR-4526	HITS-CLIP	19536157
MIRT720956	hsa-miR-6719-3p	HITS-CLIP	19536157
MIRT720955	hsa-miR-6889-3p	HITS-CLIP	19536157
MIRT720954	hsa-miR-5008-3p	HITS-CLIP	19536157
MIRT720953	hsa-miR-6737-3p	HITS-CLIP	19536157
MIRT720952	hsa-miR-7157-3p	HITS-CLIP	19536157
MIRT720951	hsa-miR-4645-3p	HITS-CLIP	19536157
MIRT720950	hsa-miR-1271-3p	HITS-CLIP	19536157
MIRT720949	hsa-miR-550a-3-5p	HITS-CLIP	19536157
MIRT720948	hsa-miR-550a-5p	HITS-CLIP	19536157
MIRT720947	hsa-miR-550b-2-5p	HITS-CLIP	19536157
MIRT708875	hsa-miR-211-3p	HITS-CLIP	19536157
MIRT708874	hsa-miR-7113-5p	HITS-CLIP	19536157
MIRT708873	hsa-miR-4685-5p	HITS-CLIP	19536157
MIRT708872	hsa-miR-6837-5p	HITS-CLIP	19536157
MIRT708871	hsa-miR-6734-3p	HITS-CLIP	19536157
MIRT708870	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT708869	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT708868	hsa-miR-3925-3p	HITS-CLIP	19536157
MIRT708867	hsa-miR-572	HITS-CLIP	19536157
MIRT643326	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT643325	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT643324	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT643323	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT643322	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT643321	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT643320	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT643319	hsa-miR-6752-3p	HITS-CLIP	23824327
MIRT643318	hsa-miR-3183	HITS-CLIP	23824327
MIRT643317	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT643316	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT643315	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT643314	hsa-miR-4469	HITS-CLIP	23824327
MIRT643313	hsa-miR-517-5p	HITS-CLIP	23824327
MIRT643312	hsa-miR-1251-5p	HITS-CLIP	23824327
MIRT643311	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT643310	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT643309	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT643308	hsa-miR-2682-3p	HITS-CLIP	23824327
MIRT643307	hsa-miR-6781-3p	HITS-CLIP	23824327
MIRT643306	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT643305	hsa-miR-1287-3p	HITS-CLIP	23824327
MIRT643304	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT503596	hsa-miR-483-3p	PAR-CLIP	23446348
MIRT503594	hsa-miR-1273g-3p	PAR-CLIP	23446348
MIRT503593	hsa-miR-4286	PAR-CLIP	23446348
MIRT503592	hsa-miR-6887-3p	PAR-CLIP	23446348
MIRT503591	hsa-miR-6795-3p	PAR-CLIP	23446348
MIRT503590	hsa-miR-6794-3p	PAR-CLIP	23446348
MIRT503589	hsa-miR-6826-3p	PAR-CLIP	23446348
MIRT503596	hsa-miR-483-3p	PAR-CLIP	23446348
MIRT503595	hsa-miR-1910-5p	PAR-CLIP	23446348
MIRT503594	hsa-miR-1273g-3p	PAR-CLIP	23446348
MIRT503593	hsa-miR-4286	PAR-CLIP	23446348
MIRT503592	hsa-miR-6887-3p	PAR-CLIP	23446348
MIRT503591	hsa-miR-6795-3p	PAR-CLIP	23446348
MIRT503590	hsa-miR-6794-3p	PAR-CLIP	23446348
MIRT503589	hsa-miR-6826-3p	PAR-CLIP	23446348
MIRT503588	hsa-miR-4691-5p	PAR-CLIP	23446348
MIRT503587	hsa-miR-6792-3p	PAR-CLIP	23446348
MIRT1431520	hsa-miR-122	CLIP-seq
MIRT1431521	hsa-miR-1303	CLIP-seq
MIRT1431522	hsa-miR-134	CLIP-seq
MIRT1431523	hsa-miR-217	CLIP-seq
MIRT1431524	hsa-miR-3118	CLIP-seq
MIRT1431525	hsa-miR-3123	CLIP-seq
MIRT1431526	hsa-miR-3168	CLIP-seq
MIRT1431527	hsa-miR-3661	CLIP-seq
MIRT1431528	hsa-miR-3689a-3p	CLIP-seq
MIRT1431529	hsa-miR-3689c	CLIP-seq
MIRT1431530	hsa-miR-3689d	CLIP-seq
MIRT1431531	hsa-miR-3925-5p	CLIP-seq
MIRT1431532	hsa-miR-4254	CLIP-seq
MIRT1431533	hsa-miR-4447	CLIP-seq
MIRT1431534	hsa-miR-4472	CLIP-seq
MIRT1431535	hsa-miR-4481	CLIP-seq
MIRT1431536	hsa-miR-4488	CLIP-seq
MIRT1431537	hsa-miR-4690-3p	CLIP-seq
MIRT1431538	hsa-miR-4697-5p	CLIP-seq
MIRT1431539	hsa-miR-4723-5p	CLIP-seq
MIRT1431540	hsa-miR-4735-5p	CLIP-seq
MIRT1431541	hsa-miR-4745-5p	CLIP-seq
MIRT1431542	hsa-miR-4755-3p	CLIP-seq
MIRT1431543	hsa-miR-512-3p	CLIP-seq
MIRT1431544	hsa-miR-541	CLIP-seq
MIRT1431545	hsa-miR-576-5p	CLIP-seq
MIRT1431546	hsa-miR-619	CLIP-seq
MIRT1431547	hsa-miR-631	CLIP-seq
MIRT1431548	hsa-miR-654-5p	CLIP-seq
MIRT1431549	hsa-miR-939	CLIP-seq
MIRT2129345	hsa-miR-1321	CLIP-seq
MIRT2129346	hsa-miR-3120-5p	CLIP-seq
MIRT2129347	hsa-miR-3136-3p	CLIP-seq
MIRT2129348	hsa-miR-3652	CLIP-seq
MIRT1431530	hsa-miR-3689d	CLIP-seq
MIRT2129349	hsa-miR-3922-5p	CLIP-seq
MIRT2129350	hsa-miR-4419a	CLIP-seq
MIRT2129351	hsa-miR-4430	CLIP-seq
MIRT2129352	hsa-miR-4446-3p	CLIP-seq
MIRT1431533	hsa-miR-4447	CLIP-seq
MIRT2129353	hsa-miR-4459	CLIP-seq
MIRT1431534	hsa-miR-4472	CLIP-seq
MIRT2129354	hsa-miR-4492	CLIP-seq
MIRT2129355	hsa-miR-4498	CLIP-seq
MIRT2129356	hsa-miR-4510	CLIP-seq
MIRT2129357	hsa-miR-4520a-3p	CLIP-seq
MIRT2129358	hsa-miR-4638-3p	CLIP-seq
MIRT1431539	hsa-miR-4723-5p	CLIP-seq
MIRT2129359	hsa-miR-4739	CLIP-seq
MIRT2129360	hsa-miR-4756-5p	CLIP-seq
MIRT2129361	hsa-miR-4779	CLIP-seq
MIRT2129362	hsa-miR-485-5p	CLIP-seq
MIRT1431544	hsa-miR-541	CLIP-seq
MIRT2129363	hsa-miR-596	CLIP-seq
MIRT1431548	hsa-miR-654-5p	CLIP-seq
MIRT2129364	hsa-miR-744	CLIP-seq
MIRT2129365	hsa-miR-762	CLIP-seq
MIRT1431549	hsa-miR-939	CLIP-seq
MIRT2350929	hsa-miR-4446-5p	CLIP-seq
MIRT2350930	hsa-miR-4755-5p	CLIP-seq
MIRT2350931	hsa-miR-670	CLIP-seq
MIRT1431530	hsa-miR-3689d	CLIP-seq
MIRT1431533	hsa-miR-4447	CLIP-seq
MIRT1431534	hsa-miR-4472	CLIP-seq
MIRT1431539	hsa-miR-4723-5p	CLIP-seq
MIRT1431544	hsa-miR-541	CLIP-seq
MIRT1431548	hsa-miR-654-5p	CLIP-seq
MIRT1431549	hsa-miR-939	CLIP-seq
MIRT2461703	hsa-miR-27a	CLIP-seq
MIRT2461704	hsa-miR-27b	CLIP-seq
MIRT2461705	hsa-miR-4675	CLIP-seq
MIRT2461706	hsa-miR-4687-3p	CLIP-seq
MIRT2461707	hsa-miR-4741	CLIP-seq
MIRT2461708	hsa-miR-513a-5p	CLIP-seq
MIRT2644524	hsa-miR-4279	CLIP-seq
MIRT2644525	hsa-miR-4290	CLIP-seq
MIRT2644524	hsa-miR-4279	CLIP-seq
MIRT2644525	hsa-miR-4290	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IW70
• Protein name: Transmembrane protein 151B (Transmembrane protein 193)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14857	TMEM151	46 → 492	TMEM151 family	Family

• Sequence:

  MSPPGSAAGESAAGGGGGGGGPGVSEELTAAAAAAAADEGPAREEQRPIQPSFTKSLCRE
  SHWKCLLLSLLMYGCLGAVAWCHVTTVTRLTFSSAYQGNSLMYHDSPCSNGYVYIPLAFL
  LMLYAVYLVECWHCQARHELQHRVDVSSVRERVGRMQQATPCIWWKAISYHYVRRTRQVT
  RYRNGDAYTTTQVYHERVNTHVAEAEFDYARCGVRDVSKTLVGLEGAPATRLRFTKCFSF
  ASVEAENAYLCQRARFFAENEGLDDYMEAREGMHLKNVDFREFMVAFPDPARPPWYACSS
  AFWAAALLTLSWPLRVLAEYRTAYAHYHVEKLFGLEGPGSASSAGGGLSPSDELLPPLTH
  RLPRVNTVDSTELEWHIRSNQQLVPSYSEAVLMDLAGLGTRCGGAGGGYAPSCRYGGVGG
  PGAAGVAPYRRSCEHCQRAVSSSSIFSRSALSICASPRAGPGPGGGAGCGGSRFSLGRLY
  GSRRSCLWRSRSGSVNEASCPTEQTRLSSQASMGDDEDDDEEEAGPPPPYHDALYFPVLI
  VHRQEGCLGHSHRPLHRHGSCVETSL

• Sequence length: 566

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CROHN'S DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POLYCYSTIC OVARY SYNDROME	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 8	Combined Oxidative Phosphorylation Deficiency	CLINVAR_DG	21549344, 22277967, 25058219, 25705216, 27839525, 29440775		★☆☆☆☆ Found in Text Mining only
Congenital hypoplasia of lung	Pulmonary hypoplasia	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Dysmorphic features	Dysmorphic Features	CLINVAR_DG	21549344, 22277967, 24808023, 25058219		★☆☆☆☆ Found in Text Mining only
Hydrops Fetalis, Non-Immune	Hydrops Fetalis	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
LEUKOENCEPHALOPATHY, PROGRESSIVE, WITH OVARIAN FAILURE	Leukoencephalopathy, With Ovarian Failure	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Multiple congenital anomalies	Multiple Congenital Anomalies	CLINVAR_DG	21549344, 22277967, 24808023, 25058219		★☆☆☆☆ Found in Text Mining only
Pericardial effusion	Pericardial effusion	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Pleural effusion disorder	Pleural effusion	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	CTD_human_DG	21411543		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sclerocystic Ovaries	Sclerocystic Ovaries	CTD_human_DG	21411543		★☆☆☆☆ Found in Text Mining only