Gene Gene information from NCBI Gene database.
Entrez ID 440730
Gene name Tripartite motif containing 67
Gene symbol TRIM67
Synonyms (NCBI Gene)
TNL
Chromosome 1
Chromosome location 1q42.2
miRNA miRNA information provided by mirtarbase database.
372
miRTarBase ID miRNA Experiments Reference
MIRT721048 hsa-miR-1911-3p HITS-CLIP 19536157
MIRT721047 hsa-miR-1226-3p HITS-CLIP 19536157
MIRT721046 hsa-miR-4733-3p HITS-CLIP 19536157
MIRT721045 hsa-miR-6884-3p HITS-CLIP 19536157
MIRT721044 hsa-miR-505-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
GO:0005856 Component Cytoskeleton IEA
GO:0008270 Function Zinc ion binding IEA
GO:0010976 Process Positive regulation of neuron projection development IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610584 31859 ENSG00000119283
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6ZTA4
Protein name Tripartite motif-containing protein 67 (TRIM9-like protein)
PDB 7QS5
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00097 zf-C3HC4 7 43 Zinc finger, C3HC4 type (RING finger) Domain
PF00643 zf-B_box 298 340 B-box zinc finger Domain
PF00041 fn3 513 597 Fibronectin type III domain Domain
PF00622 SPRY 650 770 SPRY domain Family
Sequence
MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG
AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLK
SPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRGLRGFQRNR
LLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHP
SRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKF
PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPL
GAMWKQHKAQLSQALNGVSD
KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL
KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE
PKVSAEFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFT
HSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYS
KTV
VLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRY
DNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVG
VLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLE
VPTNLGRPKL
SGN
Sequence length 783
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CENTRAL NERVOUS SYSTEM CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GLIOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OBESITY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Colorectal Carcinoma Colorectal Cancer BEFREE 31239268
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 35854778 Associate
★☆☆☆☆
Found in Text Mining only
Diabetes Gestational Gestational diabetes Pubtator 35993280 Associate
★☆☆☆☆
Found in Text Mining only
Hypertensive disease Hypertension BEFREE 28888840
★☆☆☆☆
Found in Text Mining only
Hypospadias Hypospadias Pubtator 35606856 Associate
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 31239268
★☆☆☆☆
Found in Text Mining only
Non-Small Cell Lung Carcinoma Lung carcinoma BEFREE 26599082
★☆☆☆☆
Found in Text Mining only
Obesity Obesity Pubtator 35806477 Associate
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Primary Ciliary Dyskinesia Ciliary dyskinesia BEFREE 30350014
★☆☆☆☆
Found in Text Mining only