Gene Gene information from NCBI Gene database.
Entrez ID 440270
Gene name Golgin A8 family member B
Gene symbol GOLGA8B
Synonyms (NCBI Gene)
GOLGA5
Chromosome 15
Chromosome location 15q14
miRNA miRNA information provided by mirtarbase database.
471
miRTarBase ID miRNA Experiments Reference
MIRT018688 hsa-miR-335-5p Microarray 18185580
MIRT028332 hsa-miR-32-5p Sequencing 20371350
MIRT043895 hsa-miR-378a-3p CLASH 23622248
MIRT714023 hsa-miR-383-3p HITS-CLIP 19536157
MIRT714022 hsa-miR-450b-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0000137 Component Golgi cis cisterna IBA
GO:0005794 Component Golgi apparatus IDA
GO:0005794 Component Golgi apparatus IEA
GO:0005801 Component Cis-Golgi network IBA
GO:0005801 Component Cis-Golgi network IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609619 31973 ENSG00000215252
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A8MQT2
Protein name Golgin subfamily A member 8B (Golgin-67)
Protein function May be involved in maintaining Golgi structure.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15070 GOLGA2L5 218 366 Putative golgin subfamily A member 2-like protein 5 Coiled-coil
PF19046 GM130_C 558 603 GM130 C-terminal binding motif Motif
Tissue specificity TISSUE SPECIFICITY: Highly expressed in brain, heart and kidney. Detected at lower levels in liver, thymus, spleen, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:10660574}.
Sequence
MAEETGQSKLAAAKKKFKEYWQRNRPGVPAAAKRNTKANGSSPETAASGGCHSSEASSSA
SSSLHARQSPCQEQAAVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAE
RELEGQIQRLNTEKKKLNTDLYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEWSLCAVA
ATQKKKPDGFSSRSKALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYAEQIKGE
RAQWQQRMRKMSQEVCTLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDAPAVSSEVEL
QDLRKELERVAGELQAQVENNQCISLLNRGQKERLREQEERLQEQQERLREREKRLQQLA
EPQSDL
EELKHENKSALQLEQQVKELQEKLGQVMETLTSAEKEPEAAVPASGTGGESSGL
MDLLEEKADLREHVEKLELGFIQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQ
GGEEGEAAGAAGDGVAACGSYSEGHGKFLAAARNPAAEPSPGAPAPQELGAADKHGDLCE
ASLTNSVEPAQGEAREGSSQDNPTAQPVLQLLGEMQDHQEHPGLGSNCCVPCFCWAWLPR
RRR
Sequence length 603
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
COLORECTAL CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Adenocarcinoma of large intestine Colorectal Cancer BEFREE 17899288
★☆☆☆☆
Found in Text Mining only
Alzheimer Disease Alzheimer disease Pubtator 32966694 Associate
★☆☆☆☆
Found in Text Mining only
Dementia Dementia Pubtator 32966694 Associate
★☆☆☆☆
Found in Text Mining only
Differentiated thyroid carcinoma Thyroid Carcinoma Orphanet
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 9443391
★☆☆☆☆
Found in Text Mining only
Papillary thyroid carcinoma Papillary thyroid carcinoma ORPHANET_DG 17062879, 9443391
★☆☆☆☆
Found in Text Mining only
Stroke Stroke Pubtator 32966694 Associate
★☆☆☆☆
Found in Text Mining only
Thyroid carcinoma Thyroid Carcinoma BEFREE 9443391
★☆☆☆☆
Found in Text Mining only
Thyroid Neoplasm Thyroid Neoplasm BEFREE 9443391
★☆☆☆☆
Found in Text Mining only