Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	4355
Gene name	MAGUK p55 scaffold protein 2
Gene symbol	MPP2
Synonyms (NCBI Gene)	DLG2
Chromosome	17
Chromosome location	17q21.31
Summary	Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intrace

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020593	hsa-miR-155-5p	Proteomics	18668040
MIRT021960	hsa-miR-128-3p	Microarray	17612493
MIRT028414	hsa-miR-30a-5p	Proteomics	18668040
MIRT048275	hsa-miR-196a-5p	CLASH	23622248
MIRT042248	hsa-miR-484	CLASH	23622248
MIRT040407	hsa-miR-615-3p	CLASH	23622248
MIRT038475	hsa-miR-296-3p	CLASH	23622248
MIRT036323	hsa-miR-1229-3p	CLASH	23622248
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT615501	hsa-miR-8485	HITS-CLIP	23824327
MIRT615500	hsa-miR-6767-3p	HITS-CLIP	23824327
MIRT615499	hsa-miR-6730-3p	HITS-CLIP	23824327
MIRT615498	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT615497	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT615496	hsa-miR-8064	HITS-CLIP	23824327
MIRT1156280	hsa-let-7a	CLIP-seq
MIRT1156281	hsa-let-7b	CLIP-seq
MIRT1156282	hsa-let-7c	CLIP-seq
MIRT1156283	hsa-let-7d	CLIP-seq
MIRT1156284	hsa-let-7e	CLIP-seq
MIRT1156285	hsa-let-7f	CLIP-seq
MIRT1156286	hsa-let-7g	CLIP-seq
MIRT1156287	hsa-let-7i	CLIP-seq
MIRT1156288	hsa-miR-103a	CLIP-seq
MIRT1156289	hsa-miR-107	CLIP-seq
MIRT1156290	hsa-miR-1182	CLIP-seq
MIRT1156291	hsa-miR-1193	CLIP-seq
MIRT1156292	hsa-miR-1197	CLIP-seq
MIRT1156293	hsa-miR-125a-3p	CLIP-seq
MIRT1156294	hsa-miR-1269	CLIP-seq
MIRT1156295	hsa-miR-1269b	CLIP-seq
MIRT1156296	hsa-miR-140-3p	CLIP-seq
MIRT1156297	hsa-miR-146b-3p	CLIP-seq
MIRT1156298	hsa-miR-15a	CLIP-seq
MIRT1156299	hsa-miR-15b	CLIP-seq
MIRT1156300	hsa-miR-16	CLIP-seq
MIRT1156301	hsa-miR-1913	CLIP-seq
MIRT1156302	hsa-miR-195	CLIP-seq
MIRT1156303	hsa-miR-300	CLIP-seq
MIRT1156304	hsa-miR-3125	CLIP-seq
MIRT1156305	hsa-miR-3127-3p	CLIP-seq
MIRT1156306	hsa-miR-3173-5p	CLIP-seq
MIRT1156307	hsa-miR-3192	CLIP-seq
MIRT1156308	hsa-miR-324-3p	CLIP-seq
MIRT1156309	hsa-miR-3612	CLIP-seq
MIRT1156310	hsa-miR-3613-5p	CLIP-seq
MIRT1156311	hsa-miR-3661	CLIP-seq
MIRT1156312	hsa-miR-3667-3p	CLIP-seq
MIRT1156313	hsa-miR-3671	CLIP-seq
MIRT1156314	hsa-miR-3681	CLIP-seq
MIRT1156315	hsa-miR-3689a-3p	CLIP-seq
MIRT1156316	hsa-miR-3689c	CLIP-seq
MIRT1156317	hsa-miR-3691-5p	CLIP-seq
MIRT1156318	hsa-miR-381	CLIP-seq
MIRT1156319	hsa-miR-3916	CLIP-seq
MIRT1156320	hsa-miR-3919	CLIP-seq
MIRT1156321	hsa-miR-424	CLIP-seq
MIRT1156322	hsa-miR-4266	CLIP-seq
MIRT1156323	hsa-miR-4276	CLIP-seq
MIRT1156324	hsa-miR-4279	CLIP-seq
MIRT1156325	hsa-miR-4427	CLIP-seq
MIRT1156326	hsa-miR-4436a	CLIP-seq
MIRT1156327	hsa-miR-4446-3p	CLIP-seq
MIRT1156328	hsa-miR-4457	CLIP-seq
MIRT1156329	hsa-miR-4458	CLIP-seq
MIRT1156330	hsa-miR-4496	CLIP-seq
MIRT1156331	hsa-miR-4500	CLIP-seq
MIRT1156332	hsa-miR-4520a-3p	CLIP-seq
MIRT1156333	hsa-miR-4520b-3p	CLIP-seq
MIRT1156334	hsa-miR-4529-3p	CLIP-seq
MIRT1156335	hsa-miR-4533	CLIP-seq
MIRT1156336	hsa-miR-4639-3p	CLIP-seq
MIRT1156337	hsa-miR-4656	CLIP-seq
MIRT1156338	hsa-miR-4695-5p	CLIP-seq
MIRT1156339	hsa-miR-4728-5p	CLIP-seq
MIRT1156340	hsa-miR-4747-5p	CLIP-seq
MIRT1156341	hsa-miR-4756-3p	CLIP-seq
MIRT1156342	hsa-miR-4792	CLIP-seq
MIRT1156343	hsa-miR-4797-5p	CLIP-seq
MIRT1156344	hsa-miR-485-5p	CLIP-seq
MIRT1156345	hsa-miR-497	CLIP-seq
MIRT1156346	hsa-miR-526b	CLIP-seq
MIRT1156347	hsa-miR-539	CLIP-seq
MIRT1156348	hsa-miR-548aa	CLIP-seq
MIRT1156349	hsa-miR-631	CLIP-seq
MIRT1156350	hsa-miR-642b	CLIP-seq
MIRT1156351	hsa-miR-650	CLIP-seq
MIRT1156352	hsa-miR-759	CLIP-seq
MIRT1156353	hsa-miR-767-3p	CLIP-seq
MIRT1156354	hsa-miR-874	CLIP-seq
MIRT1156355	hsa-miR-98	CLIP-seq
MIRT2044691	hsa-miR-1224-5p	CLIP-seq
MIRT2044692	hsa-miR-1252	CLIP-seq
MIRT1156293	hsa-miR-125a-3p	CLIP-seq
MIRT2044693	hsa-miR-1285	CLIP-seq
MIRT2044694	hsa-miR-1291	CLIP-seq
MIRT2044695	hsa-miR-1343	CLIP-seq
MIRT2044696	hsa-miR-139-5p	CLIP-seq
MIRT1156296	hsa-miR-140-3p	CLIP-seq
MIRT1156297	hsa-miR-146b-3p	CLIP-seq
MIRT2044697	hsa-miR-3126-3p	CLIP-seq
MIRT2044698	hsa-miR-3155	CLIP-seq
MIRT2044699	hsa-miR-3155b	CLIP-seq
MIRT2044700	hsa-miR-3187-5p	CLIP-seq
MIRT2044701	hsa-miR-328	CLIP-seq
MIRT1156310	hsa-miR-3613-5p	CLIP-seq
MIRT1156320	hsa-miR-3919	CLIP-seq
MIRT2044702	hsa-miR-3945	CLIP-seq
MIRT2044703	hsa-miR-4253	CLIP-seq
MIRT2044704	hsa-miR-4299	CLIP-seq
MIRT2044705	hsa-miR-4419a	CLIP-seq
MIRT2044706	hsa-miR-4433	CLIP-seq
MIRT2044707	hsa-miR-4438	CLIP-seq
MIRT2044708	hsa-miR-4453	CLIP-seq
MIRT2044709	hsa-miR-4456	CLIP-seq
MIRT2044710	hsa-miR-4481	CLIP-seq
MIRT2044711	hsa-miR-4510	CLIP-seq
MIRT1156335	hsa-miR-4533	CLIP-seq
MIRT2044712	hsa-miR-4538	CLIP-seq
MIRT2044713	hsa-miR-4711-5p	CLIP-seq
MIRT2044714	hsa-miR-4745-5p	CLIP-seq
MIRT2044715	hsa-miR-4751	CLIP-seq
MIRT1156341	hsa-miR-4756-3p	CLIP-seq
MIRT1156342	hsa-miR-4792	CLIP-seq
MIRT2044716	hsa-miR-513a-5p	CLIP-seq
MIRT2044717	hsa-miR-548q	CLIP-seq
MIRT2044718	hsa-miR-552	CLIP-seq
MIRT2044719	hsa-miR-612	CLIP-seq
MIRT1156350	hsa-miR-642b	CLIP-seq
MIRT2044720	hsa-miR-764	CLIP-seq
MIRT1156293	hsa-miR-125a-3p	CLIP-seq
MIRT1156297	hsa-miR-146b-3p	CLIP-seq
MIRT2273968	hsa-miR-183	CLIP-seq
MIRT2273969	hsa-miR-194	CLIP-seq
MIRT2273970	hsa-miR-214	CLIP-seq
MIRT1156304	hsa-miR-3125	CLIP-seq
MIRT1156307	hsa-miR-3192	CLIP-seq
MIRT2273971	hsa-miR-3198	CLIP-seq
MIRT2273972	hsa-miR-323b-5p	CLIP-seq
MIRT2273973	hsa-miR-3619-5p	CLIP-seq
MIRT1156319	hsa-miR-3916	CLIP-seq
MIRT1156320	hsa-miR-3919	CLIP-seq
MIRT1156322	hsa-miR-4266	CLIP-seq
MIRT2273974	hsa-miR-4294	CLIP-seq
MIRT2273975	hsa-miR-4309	CLIP-seq
MIRT2273976	hsa-miR-450b-3p	CLIP-seq
MIRT2273977	hsa-miR-4646-5p	CLIP-seq
MIRT1156338	hsa-miR-4695-5p	CLIP-seq
MIRT2273978	hsa-miR-4713-3p	CLIP-seq
MIRT1156339	hsa-miR-4728-5p	CLIP-seq
MIRT1156341	hsa-miR-4756-3p	CLIP-seq
MIRT2273979	hsa-miR-4772-5p	CLIP-seq
MIRT1156342	hsa-miR-4792	CLIP-seq
MIRT1156344	hsa-miR-485-5p	CLIP-seq
MIRT2044716	hsa-miR-513a-5p	CLIP-seq
MIRT2273980	hsa-miR-591	CLIP-seq
MIRT2273981	hsa-miR-638	CLIP-seq
MIRT2273982	hsa-miR-657	CLIP-seq
MIRT2273983	hsa-miR-761	CLIP-seq
MIRT1156353	hsa-miR-767-3p	CLIP-seq
MIRT2273984	hsa-miR-769-3p	CLIP-seq
MIRT1156293	hsa-miR-125a-3p	CLIP-seq
MIRT1156297	hsa-miR-146b-3p	CLIP-seq
MIRT2391015	hsa-miR-2861	CLIP-seq
MIRT1156342	hsa-miR-4792	CLIP-seq
MIRT2572808	hsa-miR-1184	CLIP-seq
MIRT2572809	hsa-miR-122	CLIP-seq
MIRT2572810	hsa-miR-1254	CLIP-seq
MIRT2572811	hsa-miR-1266	CLIP-seq
MIRT1156294	hsa-miR-1269	CLIP-seq
MIRT1156295	hsa-miR-1269b	CLIP-seq
MIRT2572812	hsa-miR-2277-3p	CLIP-seq
MIRT2572813	hsa-miR-24	CLIP-seq
MIRT2391015	hsa-miR-2861	CLIP-seq
MIRT2572814	hsa-miR-3064-5p	CLIP-seq
MIRT2572815	hsa-miR-3116	CLIP-seq
MIRT1156307	hsa-miR-3192	CLIP-seq
MIRT2273972	hsa-miR-323b-5p	CLIP-seq
MIRT1156309	hsa-miR-3612	CLIP-seq
MIRT2572816	hsa-miR-3614-5p	CLIP-seq
MIRT2572817	hsa-miR-3616-3p	CLIP-seq
MIRT1156315	hsa-miR-3689a-3p	CLIP-seq
MIRT1156316	hsa-miR-3689c	CLIP-seq
MIRT2572818	hsa-miR-3921	CLIP-seq
MIRT2572819	hsa-miR-4269	CLIP-seq
MIRT2572820	hsa-miR-4437	CLIP-seq
MIRT1156327	hsa-miR-4446-3p	CLIP-seq
MIRT1156328	hsa-miR-4457	CLIP-seq
MIRT2572821	hsa-miR-4511	CLIP-seq
MIRT2572822	hsa-miR-4514	CLIP-seq
MIRT2572823	hsa-miR-4518	CLIP-seq
MIRT1156333	hsa-miR-4520b-3p	CLIP-seq
MIRT1156334	hsa-miR-4529-3p	CLIP-seq
MIRT2572824	hsa-miR-4646-3p	CLIP-seq
MIRT2572825	hsa-miR-4649-3p	CLIP-seq
MIRT2572826	hsa-miR-4653-5p	CLIP-seq
MIRT2572827	hsa-miR-4675	CLIP-seq
MIRT2572828	hsa-miR-4692	CLIP-seq
MIRT2572829	hsa-miR-4721	CLIP-seq
MIRT1156339	hsa-miR-4728-5p	CLIP-seq
MIRT2572830	hsa-miR-4741	CLIP-seq
MIRT2572831	hsa-miR-4742-5p	CLIP-seq
MIRT2572832	hsa-miR-4763-5p	CLIP-seq
MIRT2572833	hsa-miR-510	CLIP-seq
MIRT2044716	hsa-miR-513a-5p	CLIP-seq
MIRT2572834	hsa-miR-597	CLIP-seq
MIRT2572835	hsa-miR-604	CLIP-seq
MIRT2572836	hsa-miR-619	CLIP-seq
MIRT2572837	hsa-miR-647	CLIP-seq
MIRT1156351	hsa-miR-650	CLIP-seq
MIRT2572838	hsa-miR-661	CLIP-seq
MIRT2572839	hsa-miR-7	CLIP-seq
MIRT2572840	hsa-miR-890	CLIP-seq
MIRT2572841	hsa-miR-940	CLIP-seq
MIRT1156280	hsa-let-7a	CLIP-seq
MIRT1156281	hsa-let-7b	CLIP-seq
MIRT1156282	hsa-let-7c	CLIP-seq
MIRT1156283	hsa-let-7d	CLIP-seq
MIRT1156284	hsa-let-7e	CLIP-seq
MIRT1156285	hsa-let-7f	CLIP-seq
MIRT1156286	hsa-let-7g	CLIP-seq
MIRT1156287	hsa-let-7i	CLIP-seq
MIRT2685229	hsa-miR-1207-5p	CLIP-seq
MIRT2572809	hsa-miR-122	CLIP-seq
MIRT2572810	hsa-miR-1254	CLIP-seq
MIRT2685230	hsa-miR-1909	CLIP-seq
MIRT2572812	hsa-miR-2277-3p	CLIP-seq
MIRT2572813	hsa-miR-24	CLIP-seq
MIRT2391015	hsa-miR-2861	CLIP-seq
MIRT2572814	hsa-miR-3064-5p	CLIP-seq
MIRT2572815	hsa-miR-3116	CLIP-seq
MIRT1156307	hsa-miR-3192	CLIP-seq
MIRT2572817	hsa-miR-3616-3p	CLIP-seq
MIRT1156315	hsa-miR-3689a-3p	CLIP-seq
MIRT1156316	hsa-miR-3689c	CLIP-seq
MIRT1156320	hsa-miR-3919	CLIP-seq
MIRT1156322	hsa-miR-4266	CLIP-seq
MIRT2572819	hsa-miR-4269	CLIP-seq
MIRT2572820	hsa-miR-4437	CLIP-seq
MIRT1156327	hsa-miR-4446-3p	CLIP-seq
MIRT1156329	hsa-miR-4458	CLIP-seq
MIRT1156331	hsa-miR-4500	CLIP-seq
MIRT2572822	hsa-miR-4514	CLIP-seq
MIRT2572827	hsa-miR-4675	CLIP-seq
MIRT2572828	hsa-miR-4692	CLIP-seq
MIRT1156338	hsa-miR-4695-5p	CLIP-seq
MIRT2572829	hsa-miR-4721	CLIP-seq
MIRT1156339	hsa-miR-4728-5p	CLIP-seq
MIRT2572830	hsa-miR-4741	CLIP-seq
MIRT2572831	hsa-miR-4742-5p	CLIP-seq
MIRT1156341	hsa-miR-4756-3p	CLIP-seq
MIRT2685231	hsa-miR-4763-3p	CLIP-seq
MIRT2572832	hsa-miR-4763-5p	CLIP-seq
MIRT1156344	hsa-miR-485-5p	CLIP-seq
MIRT2572835	hsa-miR-604	CLIP-seq
MIRT2572836	hsa-miR-619	CLIP-seq
MIRT2572837	hsa-miR-647	CLIP-seq
MIRT2572838	hsa-miR-661	CLIP-seq
MIRT1156353	hsa-miR-767-3p	CLIP-seq
MIRT2572841	hsa-miR-940	CLIP-seq
MIRT1156355	hsa-miR-98	CLIP-seq

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19665017, 25416956, 31515488, 32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IDA	19665017
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005911	Component	Cell-cell junction	IBA
GO:0014069	Component	Postsynaptic density	IEA
GO:0014069	Component	Postsynaptic density	ISS
GO:0016020	Component	Membrane	IEA
GO:0030425	Component	Dendrite	IEA
GO:0032590	Component	Dendrite membrane	ISS
GO:0042995	Component	Cell projection	IEA
GO:0043197	Component	Dendritic spine	ISS
GO:0043198	Component	Dendritic shaft	ISS
GO:0043226	Component	Organelle	IEA
GO:0045202	Component	Synapse	IEA
GO:0051260	Process	Protein homooligomerization	ISS
GO:0060079	Process	Excitatory postsynaptic potential	ISS
GO:0060291	Process	Long-term synaptic potentiation	ISS

MIM	HGNC	e!Ensembl
600723	7220	ENSG00000108852

Q14168

Protein name

MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)

Protein function

Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentia

PDB

2E7K

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02828	L27	12 → 51	L27 domain	Domain
PF02828	L27	92 → 144	L27 domain	Domain
PF00595	PDZ	165 → 240	PDZ domain	Domain
PF07653	SH3_2	253 → 315	Variant SH3 domain	Domain
PF00625	Guanylate_kin	373 → 563	Guanylate kinase	Domain

Sequence

MPVAATNSETAMQQVLDNLGSLPSATGAAELDLIFLRGIMESPIVRSLAKVIMVLWFMQQ
NVFVPMKYMLKYFGAHERLEETKLEAVRDNNLELVQEILRDLAHVAEQSSTAAELAHILQ
EPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFR
VEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRNASGSVILKIL
PSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVE
GGSAGLIPSQLLEEKRKAFVKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHEL
LIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREG
QGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVL
RTAEFVPYVVFIEAPDFETLRAMNRAALESGISTKQLTEADLRRTVEESSRIQRGYGHYF
DLCLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY

Sequence length

576

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (69)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	29885764	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyloidosis	Amyloidosis	BEFREE	28697571		★★★★★ ★☆☆☆☆ Found in Text Mining only
Anxiety	Anxiety disorder	Pubtator	30699873	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	Pubtator	23737970	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	BEFREE	27902448		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autism Spectrum Disorder	Autism	Pubtator	27271353, 35205368	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autonomic Nervous System Diseases	Autonomic nervous system disease	Pubtator	34994165	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	PSYGENET_DG	16023328, 17113057		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar disorder	Pubtator	35667888	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	Pubtator	24718460	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	33642822	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Transitional Cell	Transitional cell carcinoma	Pubtator	31805718	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	30862230, 7590743		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	GWASCAT_DG	30595370		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	25584925		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	GWASCAT_DG	25584925		★★★★★ ★☆☆☆☆ Found in Text Mining only
Common Migraine	Common Migraine	GWASCAT_DG	28952330		★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital Abnormalities	Congenital abnormalities	Pubtator	37860969	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Development Disorder	BEFREE	28724449		★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	35627244, 37860969	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glaucoma, Primary Open Angle	Glaucoma	BEFREE	28966548		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	35111846	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypogonadism	Hypogonadism	Pubtator	32341572	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	28697571, 30292394		★★★★★ ★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	30678306	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	28724449		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	35205368	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	31326116		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Neoplasm	Kidney Neoplasm	BEFREE	16640776		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Neoplasms	Kidney neoplasm	Pubtator	16640776	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25671640		★★★★★ ★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	PSYGENET_DG	16023328		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	18345025		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	30862230, 7590743		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	7590743		★★★★★ ★☆☆☆☆ Found in Text Mining only
Medulloblastoma	Medulloblastoma	Pubtator	21652733	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	CTD_human_DG	22535842		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	25450268, 29706638	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Migraine Disorders	Migraine	Pubtator	31842742	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopia	Myopia	GWASCAT_DG	27182965		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopia	Myopia	Pubtator	28966548	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	24703847, 30093633, 30862230, 7590743		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nephroblastoma	Nephroblastoma	GWASCAT_DG	22544364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nephroblastoma	Nephroblastoma	GWASDB_DG	22544364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	35217496	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodevelopmental Disorders	Neurodevelopmental Disorders	BEFREE	26460480, 30586380		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oncocytoma, renal	Oncocytoma of kidney	BEFREE	16640776		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oropharyngeal Neoplasms	Oropharyngeal neoplasm	Pubtator	26949921	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	24703847	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	30093633		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	30862230, 7590743		★★★★★ ★☆☆☆☆ Found in Text Mining only
Papilloma	Papilloma	BEFREE	10523841, 28264621		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	GWASCAT_DG	25064009, 28011712, 28892059		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	29290481		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	29290481, 34994165	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pituitary Neoplasms	Pituitary Neoplasms	BEFREE	24198235		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pituitary Neoplasms	Pituitary neoplasm	Pubtator	24198235	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	25584925	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	GWASCAT_DG	30166627		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	13130513, 16702973, 21440632, 26460480, 27055860, 29136250		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	PSYGENET_DG	13130513, 16023328, 16702973, 21440632		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	GWASCAT_DG	26198764, 28991256, 30285260		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	27271353	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia and related disorders	Schizophrenia	PSYGENET_DG	13130513		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sleep Deprivation	Sleep deprivation	Pubtator	35217496	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	24718460	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Tuberous Sclerosis	Tuberous Sclerosis	BEFREE	11758789		★★★★★ ★☆☆☆☆ Found in Text Mining only
Unipolar Depression	Mental Depression	PSYGENET_DG	16023328		★★★★★ ★☆☆☆☆ Found in Text Mining only
Wilms Tumor	Wilms tumor	Pubtator	22544364	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

MPP2 (MAGUK p55 scaffold protein 2)