Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	4201
Gene name	Male-enhanced antigen 1
Gene symbol	MEA1
Synonyms (NCBI Gene)	HYSMEA
Chromosome	6
Chromosome location	6p21.1

265

Show/Hide all (265)

miRTarBase ID	miRNA	Experiments	Reference
MIRT046830	hsa-miR-222-3p	CLASH	23622248
MIRT043158	hsa-miR-324-5p	CLASH	23622248
MIRT440263	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440263	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT1139707	hsa-miR-106a	CLIP-seq
MIRT1139708	hsa-miR-106b	CLIP-seq
MIRT1139709	hsa-miR-1253	CLIP-seq
MIRT1139710	hsa-miR-142-5p	CLIP-seq
MIRT1139711	hsa-miR-17	CLIP-seq
MIRT1139712	hsa-miR-193a-5p	CLIP-seq
MIRT1139713	hsa-miR-20a	CLIP-seq
MIRT1139714	hsa-miR-20b	CLIP-seq
MIRT1139715	hsa-miR-2964a-5p	CLIP-seq
MIRT1139716	hsa-miR-3190	CLIP-seq
MIRT1139717	hsa-miR-3609	CLIP-seq
MIRT1139718	hsa-miR-3688-3p	CLIP-seq
MIRT1139719	hsa-miR-3921	CLIP-seq
MIRT1139720	hsa-miR-3978	CLIP-seq
MIRT1139721	hsa-miR-4251	CLIP-seq
MIRT1139722	hsa-miR-4271	CLIP-seq
MIRT1139723	hsa-miR-4312	CLIP-seq
MIRT1139724	hsa-miR-4329	CLIP-seq
MIRT1139725	hsa-miR-4426	CLIP-seq
MIRT1139726	hsa-miR-4427	CLIP-seq
MIRT1139727	hsa-miR-4491	CLIP-seq
MIRT1139728	hsa-miR-4502	CLIP-seq
MIRT1139729	hsa-miR-4535	CLIP-seq
MIRT1139730	hsa-miR-455-5p	CLIP-seq
MIRT1139731	hsa-miR-4647	CLIP-seq
MIRT1139732	hsa-miR-4653-5p	CLIP-seq
MIRT1139733	hsa-miR-4657	CLIP-seq
MIRT1139734	hsa-miR-4662b	CLIP-seq
MIRT1139735	hsa-miR-4694-3p	CLIP-seq
MIRT1139736	hsa-miR-4725-3p	CLIP-seq
MIRT1139737	hsa-miR-4776-5p	CLIP-seq
MIRT1139738	hsa-miR-4796-3p	CLIP-seq
MIRT1139739	hsa-miR-483-5p	CLIP-seq
MIRT1139740	hsa-miR-519d	CLIP-seq
MIRT1139741	hsa-miR-548ah	CLIP-seq
MIRT1139742	hsa-miR-550a	CLIP-seq
MIRT1139743	hsa-miR-593	CLIP-seq
MIRT1139744	hsa-miR-93	CLIP-seq
MIRT1139707	hsa-miR-106a	CLIP-seq
MIRT1139708	hsa-miR-106b	CLIP-seq
MIRT1139710	hsa-miR-142-5p	CLIP-seq
MIRT2039508	hsa-miR-1587	CLIP-seq
MIRT1139711	hsa-miR-17	CLIP-seq
MIRT2039509	hsa-miR-18a	CLIP-seq
MIRT2039510	hsa-miR-18b	CLIP-seq
MIRT1139713	hsa-miR-20a	CLIP-seq
MIRT1139714	hsa-miR-20b	CLIP-seq
MIRT1139715	hsa-miR-2964a-5p	CLIP-seq
MIRT2039511	hsa-miR-3147	CLIP-seq
MIRT1139716	hsa-miR-3190	CLIP-seq
MIRT1139717	hsa-miR-3609	CLIP-seq
MIRT2039512	hsa-miR-3940-5p	CLIP-seq
MIRT1139720	hsa-miR-3978	CLIP-seq
MIRT1139723	hsa-miR-4312	CLIP-seq
MIRT1139726	hsa-miR-4427	CLIP-seq
MIRT1139727	hsa-miR-4491	CLIP-seq
MIRT1139728	hsa-miR-4502	CLIP-seq
MIRT2039513	hsa-miR-4507	CLIP-seq
MIRT1139729	hsa-miR-4535	CLIP-seq
MIRT1139730	hsa-miR-455-5p	CLIP-seq
MIRT2039514	hsa-miR-4639-5p	CLIP-seq
MIRT1139733	hsa-miR-4657	CLIP-seq
MIRT2039515	hsa-miR-4674	CLIP-seq
MIRT2039516	hsa-miR-4735-3p	CLIP-seq
MIRT1139737	hsa-miR-4776-5p	CLIP-seq
MIRT1139738	hsa-miR-4796-3p	CLIP-seq
MIRT1139739	hsa-miR-483-5p	CLIP-seq
MIRT1139740	hsa-miR-519d	CLIP-seq
MIRT1139741	hsa-miR-548ah	CLIP-seq
MIRT1139742	hsa-miR-550a	CLIP-seq
MIRT1139744	hsa-miR-93	CLIP-seq
MIRT2269483	hsa-miR-1910	CLIP-seq
MIRT1139716	hsa-miR-3190	CLIP-seq
MIRT1139718	hsa-miR-3688-3p	CLIP-seq
MIRT1139720	hsa-miR-3978	CLIP-seq
MIRT1139722	hsa-miR-4271	CLIP-seq
MIRT1139723	hsa-miR-4312	CLIP-seq
MIRT1139725	hsa-miR-4426	CLIP-seq
MIRT1139727	hsa-miR-4491	CLIP-seq
MIRT2269484	hsa-miR-455-3p	CLIP-seq
MIRT1139731	hsa-miR-4647	CLIP-seq
MIRT1139733	hsa-miR-4657	CLIP-seq
MIRT1139734	hsa-miR-4662b	CLIP-seq
MIRT1139735	hsa-miR-4694-3p	CLIP-seq
MIRT1139736	hsa-miR-4725-3p	CLIP-seq
MIRT2269485	hsa-miR-4764-5p	CLIP-seq
MIRT1139739	hsa-miR-483-5p	CLIP-seq
MIRT1139742	hsa-miR-550a	CLIP-seq
MIRT1139707	hsa-miR-106a	CLIP-seq
MIRT1139708	hsa-miR-106b	CLIP-seq
MIRT1139710	hsa-miR-142-5p	CLIP-seq
MIRT1139711	hsa-miR-17	CLIP-seq
MIRT1139712	hsa-miR-193a-5p	CLIP-seq
MIRT1139713	hsa-miR-20a	CLIP-seq
MIRT1139714	hsa-miR-20b	CLIP-seq
MIRT1139715	hsa-miR-2964a-5p	CLIP-seq
MIRT1139717	hsa-miR-3609	CLIP-seq
MIRT1139726	hsa-miR-4427	CLIP-seq
MIRT1139738	hsa-miR-4796-3p	CLIP-seq
MIRT1139740	hsa-miR-519d	CLIP-seq
MIRT1139741	hsa-miR-548ah	CLIP-seq
MIRT1139744	hsa-miR-93	CLIP-seq
MIRT1139707	hsa-miR-106a	CLIP-seq
MIRT1139708	hsa-miR-106b	CLIP-seq
MIRT1139709	hsa-miR-1253	CLIP-seq
MIRT1139710	hsa-miR-142-5p	CLIP-seq
MIRT2039508	hsa-miR-1587	CLIP-seq
MIRT1139711	hsa-miR-17	CLIP-seq
MIRT2039509	hsa-miR-18a	CLIP-seq
MIRT2039510	hsa-miR-18b	CLIP-seq
MIRT1139712	hsa-miR-193a-5p	CLIP-seq
MIRT1139713	hsa-miR-20a	CLIP-seq
MIRT1139714	hsa-miR-20b	CLIP-seq
MIRT1139715	hsa-miR-2964a-5p	CLIP-seq
MIRT2039511	hsa-miR-3147	CLIP-seq
MIRT1139717	hsa-miR-3609	CLIP-seq
MIRT1139719	hsa-miR-3921	CLIP-seq
MIRT2039512	hsa-miR-3940-5p	CLIP-seq
MIRT1139721	hsa-miR-4251	CLIP-seq
MIRT1139724	hsa-miR-4329	CLIP-seq
MIRT1139726	hsa-miR-4427	CLIP-seq
MIRT2039513	hsa-miR-4507	CLIP-seq
MIRT1139729	hsa-miR-4535	CLIP-seq
MIRT2039514	hsa-miR-4639-5p	CLIP-seq
MIRT1139732	hsa-miR-4653-5p	CLIP-seq
MIRT2039515	hsa-miR-4674	CLIP-seq
MIRT2039516	hsa-miR-4735-3p	CLIP-seq
MIRT1139737	hsa-miR-4776-5p	CLIP-seq
MIRT1139738	hsa-miR-4796-3p	CLIP-seq
MIRT1139740	hsa-miR-519d	CLIP-seq
MIRT1139741	hsa-miR-548ah	CLIP-seq
MIRT1139743	hsa-miR-593	CLIP-seq
MIRT1139744	hsa-miR-93	CLIP-seq
MIRT1139707	hsa-miR-106a	CLIP-seq
MIRT1139708	hsa-miR-106b	CLIP-seq
MIRT1139710	hsa-miR-142-5p	CLIP-seq
MIRT2039508	hsa-miR-1587	CLIP-seq
MIRT1139711	hsa-miR-17	CLIP-seq
MIRT2039509	hsa-miR-18a	CLIP-seq
MIRT2039510	hsa-miR-18b	CLIP-seq
MIRT1139712	hsa-miR-193a-5p	CLIP-seq
MIRT1139713	hsa-miR-20a	CLIP-seq
MIRT1139714	hsa-miR-20b	CLIP-seq
MIRT1139715	hsa-miR-2964a-5p	CLIP-seq
MIRT2039511	hsa-miR-3147	CLIP-seq
MIRT1139717	hsa-miR-3609	CLIP-seq
MIRT1139719	hsa-miR-3921	CLIP-seq
MIRT2039512	hsa-miR-3940-5p	CLIP-seq
MIRT1139726	hsa-miR-4427	CLIP-seq
MIRT2039513	hsa-miR-4507	CLIP-seq
MIRT1139729	hsa-miR-4535	CLIP-seq
MIRT2039514	hsa-miR-4639-5p	CLIP-seq
MIRT1139732	hsa-miR-4653-5p	CLIP-seq
MIRT2039515	hsa-miR-4674	CLIP-seq
MIRT2039516	hsa-miR-4735-3p	CLIP-seq
MIRT1139737	hsa-miR-4776-5p	CLIP-seq
MIRT1139738	hsa-miR-4796-3p	CLIP-seq
MIRT1139740	hsa-miR-519d	CLIP-seq
MIRT1139741	hsa-miR-548ah	CLIP-seq
MIRT1139743	hsa-miR-593	CLIP-seq
MIRT1139744	hsa-miR-93	CLIP-seq
MIRT1139707	hsa-miR-106a	CLIP-seq
MIRT1139708	hsa-miR-106b	CLIP-seq
MIRT1139709	hsa-miR-1253	CLIP-seq
MIRT1139710	hsa-miR-142-5p	CLIP-seq
MIRT2039508	hsa-miR-1587	CLIP-seq
MIRT1139711	hsa-miR-17	CLIP-seq
MIRT2039509	hsa-miR-18a	CLIP-seq
MIRT2039510	hsa-miR-18b	CLIP-seq
MIRT2269483	hsa-miR-1910	CLIP-seq
MIRT1139712	hsa-miR-193a-5p	CLIP-seq
MIRT1139713	hsa-miR-20a	CLIP-seq
MIRT1139714	hsa-miR-20b	CLIP-seq
MIRT1139715	hsa-miR-2964a-5p	CLIP-seq
MIRT2039511	hsa-miR-3147	CLIP-seq
MIRT1139716	hsa-miR-3190	CLIP-seq
MIRT2568778	hsa-miR-323-3p	CLIP-seq
MIRT1139717	hsa-miR-3609	CLIP-seq
MIRT1139718	hsa-miR-3688-3p	CLIP-seq
MIRT1139719	hsa-miR-3921	CLIP-seq
MIRT2039512	hsa-miR-3940-5p	CLIP-seq
MIRT1139720	hsa-miR-3978	CLIP-seq
MIRT1139721	hsa-miR-4251	CLIP-seq
MIRT1139722	hsa-miR-4271	CLIP-seq
MIRT1139723	hsa-miR-4312	CLIP-seq
MIRT1139724	hsa-miR-4329	CLIP-seq
MIRT1139725	hsa-miR-4426	CLIP-seq
MIRT1139726	hsa-miR-4427	CLIP-seq
MIRT1139727	hsa-miR-4491	CLIP-seq
MIRT1139728	hsa-miR-4502	CLIP-seq
MIRT2039513	hsa-miR-4507	CLIP-seq
MIRT1139729	hsa-miR-4535	CLIP-seq
MIRT2269484	hsa-miR-455-3p	CLIP-seq
MIRT1139730	hsa-miR-455-5p	CLIP-seq
MIRT2039514	hsa-miR-4639-5p	CLIP-seq
MIRT1139731	hsa-miR-4647	CLIP-seq
MIRT1139732	hsa-miR-4653-5p	CLIP-seq
MIRT1139733	hsa-miR-4657	CLIP-seq
MIRT1139734	hsa-miR-4662b	CLIP-seq
MIRT2039515	hsa-miR-4674	CLIP-seq
MIRT1139735	hsa-miR-4694-3p	CLIP-seq
MIRT1139736	hsa-miR-4725-3p	CLIP-seq
MIRT2039516	hsa-miR-4735-3p	CLIP-seq
MIRT2269485	hsa-miR-4764-5p	CLIP-seq
MIRT1139737	hsa-miR-4776-5p	CLIP-seq
MIRT1139738	hsa-miR-4796-3p	CLIP-seq
MIRT1139739	hsa-miR-483-5p	CLIP-seq
MIRT1139740	hsa-miR-519d	CLIP-seq
MIRT1139741	hsa-miR-548ah	CLIP-seq
MIRT1139742	hsa-miR-550a	CLIP-seq
MIRT1139743	hsa-miR-593	CLIP-seq
MIRT1139744	hsa-miR-93	CLIP-seq
MIRT1139707	hsa-miR-106a	CLIP-seq
MIRT1139708	hsa-miR-106b	CLIP-seq
MIRT1139709	hsa-miR-1253	CLIP-seq
MIRT1139710	hsa-miR-142-5p	CLIP-seq
MIRT2039508	hsa-miR-1587	CLIP-seq
MIRT1139711	hsa-miR-17	CLIP-seq
MIRT2039509	hsa-miR-18a	CLIP-seq
MIRT2039510	hsa-miR-18b	CLIP-seq
MIRT1139712	hsa-miR-193a-5p	CLIP-seq
MIRT1139713	hsa-miR-20a	CLIP-seq
MIRT1139714	hsa-miR-20b	CLIP-seq
MIRT1139715	hsa-miR-2964a-5p	CLIP-seq
MIRT2039511	hsa-miR-3147	CLIP-seq
MIRT1139716	hsa-miR-3190	CLIP-seq
MIRT2568778	hsa-miR-323-3p	CLIP-seq
MIRT1139717	hsa-miR-3609	CLIP-seq
MIRT1139718	hsa-miR-3688-3p	CLIP-seq
MIRT1139719	hsa-miR-3921	CLIP-seq
MIRT2039512	hsa-miR-3940-5p	CLIP-seq
MIRT1139720	hsa-miR-3978	CLIP-seq
MIRT1139721	hsa-miR-4251	CLIP-seq
MIRT1139722	hsa-miR-4271	CLIP-seq
MIRT1139723	hsa-miR-4312	CLIP-seq
MIRT1139724	hsa-miR-4329	CLIP-seq
MIRT1139725	hsa-miR-4426	CLIP-seq
MIRT1139726	hsa-miR-4427	CLIP-seq
MIRT1139727	hsa-miR-4491	CLIP-seq
MIRT1139728	hsa-miR-4502	CLIP-seq
MIRT2039513	hsa-miR-4507	CLIP-seq
MIRT1139729	hsa-miR-4535	CLIP-seq
MIRT1139730	hsa-miR-455-5p	CLIP-seq
MIRT2039514	hsa-miR-4639-5p	CLIP-seq
MIRT1139731	hsa-miR-4647	CLIP-seq
MIRT1139732	hsa-miR-4653-5p	CLIP-seq
MIRT1139733	hsa-miR-4657	CLIP-seq
MIRT1139734	hsa-miR-4662b	CLIP-seq
MIRT2039515	hsa-miR-4674	CLIP-seq
MIRT1139735	hsa-miR-4694-3p	CLIP-seq
MIRT1139736	hsa-miR-4725-3p	CLIP-seq
MIRT2039516	hsa-miR-4735-3p	CLIP-seq
MIRT2269485	hsa-miR-4764-5p	CLIP-seq
MIRT1139737	hsa-miR-4776-5p	CLIP-seq
MIRT1139738	hsa-miR-4796-3p	CLIP-seq
MIRT1139739	hsa-miR-483-5p	CLIP-seq
MIRT1139740	hsa-miR-519d	CLIP-seq
MIRT1139741	hsa-miR-548ah	CLIP-seq
MIRT1139742	hsa-miR-550a	CLIP-seq
MIRT1139743	hsa-miR-593	CLIP-seq
MIRT1139744	hsa-miR-93	CLIP-seq

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0007283	Process	Spermatogenesis	TAS	2813404
GO:0008584	Process	Male gonad development	TAS	2813404
GO:0030154	Process	Cell differentiation	IEA

MIM	HGNC	e!Ensembl
143170	6986	ENSG00000124733

Q16626

Protein name

Male-enhanced antigen 1 (MEA-1)

Protein function

May play an important role in spermatogenesis and/or testis development.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06910	MEA1	66 → 181		Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in testis.

Sequence

MGPERHLSGAPARMATVVLGGDTMGPERIFPNQTEELGHQGPSEGTGDWSSEEPEEEQEE
TGSGPAGYSYQPLNQDPEQEEVELAPVGDGDVVADIQDRIQALGLHLPDPPLESEDEDEE
GATALNNHSSIPMDPEHVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVVQKALQARQA
SPAWK

Sequence length

185

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
GLOBAL DEVELOPMENTAL DELAY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL DOMINANT 35	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DISABILITY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Maple Syrup Urine Disease	Maple Syrup Urine Disease	BEFREE	15725595	★★★★★ ★☆☆☆☆ Found in Text Mining only
Medullary carcinoma of thyroid	Megalencephaly, Polymicrogyria, Polydactyly, Hydrocephalus Syndrome	BEFREE	7199015	★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Endocrine Neoplasia	Multiple Endocrine Neoplasia	BEFREE	7199015	★★★★★ ★☆☆☆☆ Found in Text Mining only

MEA1 (male-enhanced antigen 1)