Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	415116
Gene name	Pim-3 proto-oncogene, serine/threonine kinase
Gene symbol	PIM3
Synonyms (NCBI Gene)	pim-3
Chromosome	22
Chromosome location	22q13.33
Summary	The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transd

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019570	hsa-miR-340-5p	Sequencing	20371350
MIRT028210	hsa-miR-33a-5p	Sequencing	20371350
MIRT043598	hsa-miR-151a-3p	CLASH	23622248
MIRT039901	hsa-miR-615-3p	CLASH	23622248
MIRT037665	hsa-miR-744-5p	CLASH	23622248
MIRT036626	hsa-miR-940	CLASH	23622248
MIRT566421	hsa-miR-203a-3p	PAR-CLIP	20371350
MIRT088271	hsa-miR-4517	PAR-CLIP	20371350
MIRT566420	hsa-miR-3163	PAR-CLIP	20371350
MIRT566419	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT566418	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT566417	hsa-miR-4695-3p	PAR-CLIP	20371350
MIRT088272	hsa-miR-7641	PAR-CLIP	20371350
MIRT088270	hsa-miR-568	PAR-CLIP	20371350
MIRT471055	hsa-miR-3150a-5p	PAR-CLIP	23592263
MIRT471054	hsa-miR-3150b-5p	PAR-CLIP	23592263
MIRT353104	hsa-miR-3125	PAR-CLIP	23592263
MIRT353106	hsa-miR-3916	PAR-CLIP	23592263
MIRT353115	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT353103	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT353111	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT353107	hsa-miR-4494	PAR-CLIP	23592263
MIRT353114	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471053	hsa-miR-4257	PAR-CLIP	23592263
MIRT353101	hsa-miR-767-3p	PAR-CLIP	23592263
MIRT353102	hsa-miR-1827	PAR-CLIP	23592263
MIRT353109	hsa-miR-4771	PAR-CLIP	23592263
MIRT254870	hsa-miR-3934-3p	PAR-CLIP	23592263
MIRT471052	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT353112	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT353116	hsa-miR-8085	PAR-CLIP	23592263
MIRT471051	hsa-miR-4489	PAR-CLIP	23592263
MIRT471050	hsa-miR-4283	PAR-CLIP	23592263
MIRT471049	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT353100	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT353099	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT353113	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT471048	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT471047	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT471046	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT471045	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT471044	hsa-miR-3689c	PAR-CLIP	23592263
MIRT471043	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT471042	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT471041	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT028210	hsa-miR-33a-5p	ImmunoprecipitaionLuciferase reporter assayqRT-PCRWestern blot	25971209
MIRT471048	hsa-miR-1273h-5p	PAR-CLIP	26701625
MIRT353102	hsa-miR-1827	PAR-CLIP	26701625
MIRT353103	hsa-miR-1910-3p	PAR-CLIP	26701625
MIRT471047	hsa-miR-30b-3p	PAR-CLIP	26701625
MIRT353100	hsa-miR-30c-1-3p	PAR-CLIP	26701625
MIRT353099	hsa-miR-30c-2-3p	PAR-CLIP	26701625
MIRT353104	hsa-miR-3125	PAR-CLIP	26701625
MIRT471055	hsa-miR-3150a-5p	PAR-CLIP	26701625
MIRT471054	hsa-miR-3150b-5p	PAR-CLIP	26701625
MIRT471046	hsa-miR-3689a-3p	PAR-CLIP	26701625
MIRT471045	hsa-miR-3689b-3p	PAR-CLIP	26701625
MIRT471044	hsa-miR-3689c	PAR-CLIP	26701625
MIRT353106	hsa-miR-3916	PAR-CLIP	26701625
MIRT254870	hsa-miR-3934-3p	PAR-CLIP	26701625
MIRT471053	hsa-miR-4257	PAR-CLIP	26701625
MIRT353107	hsa-miR-4494	PAR-CLIP	26701625
MIRT353109	hsa-miR-4771	PAR-CLIP	26701625
MIRT353111	hsa-miR-6511a-5p	PAR-CLIP	26701625
MIRT353112	hsa-miR-6731-5p	PAR-CLIP	26701625
MIRT471043	hsa-miR-6779-5p	PAR-CLIP	26701625
MIRT471042	hsa-miR-6780a-5p	PAR-CLIP	26701625
MIRT353113	hsa-miR-6788-5p	PAR-CLIP	26701625
MIRT353114	hsa-miR-6847-5p	PAR-CLIP	26701625
MIRT353115	hsa-miR-6859-5p	PAR-CLIP	26701625
MIRT471052	hsa-miR-6878-5p	PAR-CLIP	26701625
MIRT353101	hsa-miR-767-3p	PAR-CLIP	26701625
MIRT353116	hsa-miR-8085	PAR-CLIP	26701625
MIRT471041	hsa-miR-887-5p	PAR-CLIP	26701625
MIRT566421	hsa-miR-203a-3p	PAR-CLIP	20371350
MIRT088271	hsa-miR-4517	PAR-CLIP	20371350
MIRT566420	hsa-miR-3163	PAR-CLIP	20371350
MIRT566419	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT566418	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT566417	hsa-miR-4695-3p	PAR-CLIP	20371350
MIRT088272	hsa-miR-7641	PAR-CLIP	20371350
MIRT088270	hsa-miR-568	PAR-CLIP	20371350
MIRT471055	hsa-miR-3150a-5p	PAR-CLIP	23592263
MIRT471054	hsa-miR-3150b-5p	PAR-CLIP	23592263
MIRT353104	hsa-miR-3125	PAR-CLIP	23592263
MIRT353106	hsa-miR-3916	PAR-CLIP	23592263
MIRT353115	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT353103	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT353111	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT353107	hsa-miR-4494	PAR-CLIP	23592263
MIRT353114	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471053	hsa-miR-4257	PAR-CLIP	23592263
MIRT353101	hsa-miR-767-3p	PAR-CLIP	23592263
MIRT353102	hsa-miR-1827	PAR-CLIP	23592263
MIRT353109	hsa-miR-4771	PAR-CLIP	23592263
MIRT254870	hsa-miR-3934-3p	PAR-CLIP	23592263
MIRT471052	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT353112	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT353116	hsa-miR-8085	PAR-CLIP	23592263
MIRT471051	hsa-miR-4489	PAR-CLIP	23592263
MIRT471050	hsa-miR-4283	PAR-CLIP	23592263
MIRT471049	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT353100	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT353099	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT353113	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT471048	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT471047	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT471046	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT471045	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT471044	hsa-miR-3689c	PAR-CLIP	23592263
MIRT471043	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT471042	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT471041	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT1235212	hsa-miR-1206	CLIP-seq
MIRT1235213	hsa-miR-1226	CLIP-seq
MIRT1235214	hsa-miR-1254	CLIP-seq
MIRT1235215	hsa-miR-125a-3p	CLIP-seq
MIRT1235216	hsa-miR-1276	CLIP-seq
MIRT1235217	hsa-miR-128	CLIP-seq
MIRT1235218	hsa-miR-1281	CLIP-seq
MIRT1235219	hsa-miR-1284	CLIP-seq
MIRT1235220	hsa-miR-1285	CLIP-seq
MIRT1235221	hsa-miR-1286	CLIP-seq
MIRT1235222	hsa-miR-1297	CLIP-seq
MIRT1235223	hsa-miR-1301	CLIP-seq
MIRT1235224	hsa-miR-1302	CLIP-seq
MIRT1235225	hsa-miR-147	CLIP-seq
MIRT1235226	hsa-miR-1471	CLIP-seq
MIRT1235227	hsa-miR-1539	CLIP-seq
MIRT1235228	hsa-miR-15a	CLIP-seq
MIRT1235229	hsa-miR-15b	CLIP-seq
MIRT1235230	hsa-miR-16	CLIP-seq
MIRT1235231	hsa-miR-1915	CLIP-seq
MIRT1235232	hsa-miR-195	CLIP-seq
MIRT1235233	hsa-miR-2115	CLIP-seq
MIRT1235234	hsa-miR-26a	CLIP-seq
MIRT1235235	hsa-miR-26b	CLIP-seq
MIRT1235236	hsa-miR-3116	CLIP-seq
MIRT1235237	hsa-miR-3122	CLIP-seq
MIRT1235238	hsa-miR-3141	CLIP-seq
MIRT1235239	hsa-miR-3150b-3p	CLIP-seq
MIRT1235240	hsa-miR-3169	CLIP-seq
MIRT1235241	hsa-miR-3170	CLIP-seq
MIRT1235242	hsa-miR-3176	CLIP-seq
MIRT1235243	hsa-miR-3178	CLIP-seq
MIRT1235244	hsa-miR-3182	CLIP-seq
MIRT1235245	hsa-miR-3184	CLIP-seq
MIRT1235246	hsa-miR-3187-5p	CLIP-seq
MIRT1235247	hsa-miR-3195	CLIP-seq
MIRT1235248	hsa-miR-323-5p	CLIP-seq
MIRT1235249	hsa-miR-329	CLIP-seq
MIRT1235250	hsa-miR-331-3p	CLIP-seq
MIRT1235251	hsa-miR-33a	CLIP-seq
MIRT1235252	hsa-miR-33b	CLIP-seq
MIRT1235253	hsa-miR-3545-3p	CLIP-seq
MIRT1235254	hsa-miR-3616-3p	CLIP-seq
MIRT1235255	hsa-miR-362-3p	CLIP-seq
MIRT1235256	hsa-miR-3649	CLIP-seq
MIRT1235257	hsa-miR-3660	CLIP-seq
MIRT1235258	hsa-miR-3665	CLIP-seq
MIRT1235259	hsa-miR-3687	CLIP-seq
MIRT1235260	hsa-miR-3689d	CLIP-seq
MIRT1235261	hsa-miR-3691-3p	CLIP-seq
MIRT1235262	hsa-miR-3714	CLIP-seq
MIRT1235263	hsa-miR-377	CLIP-seq
MIRT1235264	hsa-miR-3913-5p	CLIP-seq
MIRT1235265	hsa-miR-3922-3p	CLIP-seq
MIRT1235266	hsa-miR-3926	CLIP-seq
MIRT1235267	hsa-miR-3934	CLIP-seq
MIRT1235268	hsa-miR-3944-5p	CLIP-seq
MIRT1235269	hsa-miR-423-5p	CLIP-seq
MIRT1235270	hsa-miR-424	CLIP-seq
MIRT1235271	hsa-miR-4256	CLIP-seq
MIRT1235272	hsa-miR-4281	CLIP-seq
MIRT1235273	hsa-miR-4286	CLIP-seq
MIRT1235274	hsa-miR-4289	CLIP-seq
MIRT1235275	hsa-miR-4292	CLIP-seq
MIRT1235276	hsa-miR-4298	CLIP-seq
MIRT1235277	hsa-miR-4417	CLIP-seq
MIRT1235278	hsa-miR-4442	CLIP-seq
MIRT1235279	hsa-miR-4459	CLIP-seq
MIRT1235280	hsa-miR-4465	CLIP-seq
MIRT1235281	hsa-miR-4493	CLIP-seq
MIRT1235282	hsa-miR-4514	CLIP-seq
MIRT1235283	hsa-miR-4526	CLIP-seq
MIRT1235284	hsa-miR-4660	CLIP-seq
MIRT1235285	hsa-miR-4662a-5p	CLIP-seq
MIRT1235286	hsa-miR-4666-5p	CLIP-seq
MIRT1235287	hsa-miR-4667-5p	CLIP-seq
MIRT1235288	hsa-miR-4685-5p	CLIP-seq
MIRT1235289	hsa-miR-4692	CLIP-seq
MIRT1235290	hsa-miR-4700-5p	CLIP-seq
MIRT1235291	hsa-miR-4721	CLIP-seq
MIRT1235292	hsa-miR-4722-5p	CLIP-seq
MIRT1235293	hsa-miR-4725-5p	CLIP-seq
MIRT1235294	hsa-miR-4726-3p	CLIP-seq
MIRT1235295	hsa-miR-4733-3p	CLIP-seq
MIRT1235296	hsa-miR-4736	CLIP-seq
MIRT1235297	hsa-miR-4740-5p	CLIP-seq
MIRT1235298	hsa-miR-4747-5p	CLIP-seq
MIRT1235299	hsa-miR-4763-5p	CLIP-seq
MIRT1235300	hsa-miR-4766-5p	CLIP-seq
MIRT1235301	hsa-miR-4767	CLIP-seq
MIRT1235302	hsa-miR-4784	CLIP-seq
MIRT1235303	hsa-miR-497	CLIP-seq
MIRT1235304	hsa-miR-504	CLIP-seq
MIRT1235305	hsa-miR-5047	CLIP-seq
MIRT1235306	hsa-miR-515-3p	CLIP-seq
MIRT1235307	hsa-miR-516a-3p	CLIP-seq
MIRT1235308	hsa-miR-519e	CLIP-seq
MIRT1235309	hsa-miR-520d-5p	CLIP-seq
MIRT1235310	hsa-miR-524-5p	CLIP-seq
MIRT1235311	hsa-miR-539	CLIP-seq
MIRT1235312	hsa-miR-541	CLIP-seq
MIRT1235313	hsa-miR-548aa	CLIP-seq
MIRT1235314	hsa-miR-548s	CLIP-seq
MIRT1235315	hsa-miR-550a	CLIP-seq
MIRT1235316	hsa-miR-580	CLIP-seq
MIRT1235317	hsa-miR-612	CLIP-seq
MIRT1235318	hsa-miR-637	CLIP-seq
MIRT1235319	hsa-miR-654-5p	CLIP-seq
MIRT1235320	hsa-miR-658	CLIP-seq
MIRT1235321	hsa-miR-661	CLIP-seq
MIRT1235322	hsa-miR-764	CLIP-seq
MIRT1235323	hsa-miR-765	CLIP-seq
MIRT1235324	hsa-miR-766	CLIP-seq
MIRT1235254	hsa-miR-3616-3p	CLIP-seq
MIRT1235312	hsa-miR-541	CLIP-seq
MIRT1235319	hsa-miR-654-5p	CLIP-seq
MIRT1235254	hsa-miR-3616-3p	CLIP-seq
MIRT1235291	hsa-miR-4721	CLIP-seq
MIRT2069248	hsa-miR-1182	CLIP-seq
MIRT2069249	hsa-miR-1228	CLIP-seq
MIRT1235215	hsa-miR-125a-3p	CLIP-seq
MIRT1235222	hsa-miR-1297	CLIP-seq
MIRT1235223	hsa-miR-1301	CLIP-seq
MIRT1235228	hsa-miR-15a	CLIP-seq
MIRT1235229	hsa-miR-15b	CLIP-seq
MIRT1235230	hsa-miR-16	CLIP-seq
MIRT2069250	hsa-miR-1908	CLIP-seq
MIRT1235231	hsa-miR-1915	CLIP-seq
MIRT1235232	hsa-miR-195	CLIP-seq
MIRT1235233	hsa-miR-2115	CLIP-seq
MIRT1235234	hsa-miR-26a	CLIP-seq
MIRT1235235	hsa-miR-26b	CLIP-seq
MIRT2069251	hsa-miR-3133	CLIP-seq
MIRT1235239	hsa-miR-3150b-3p	CLIP-seq
MIRT2069252	hsa-miR-3155	CLIP-seq
MIRT2069253	hsa-miR-3155b	CLIP-seq
MIRT1235241	hsa-miR-3170	CLIP-seq
MIRT1235242	hsa-miR-3176	CLIP-seq
MIRT1235245	hsa-miR-3184	CLIP-seq
MIRT1235253	hsa-miR-3545-3p	CLIP-seq
MIRT1235263	hsa-miR-377	CLIP-seq
MIRT1235265	hsa-miR-3922-3p	CLIP-seq
MIRT1235267	hsa-miR-3934	CLIP-seq
MIRT2069254	hsa-miR-3937	CLIP-seq
MIRT2069255	hsa-miR-3942-3p	CLIP-seq
MIRT1235268	hsa-miR-3944-5p	CLIP-seq
MIRT1235269	hsa-miR-423-5p	CLIP-seq
MIRT1235270	hsa-miR-424	CLIP-seq
MIRT2069256	hsa-miR-4269	CLIP-seq
MIRT1235279	hsa-miR-4459	CLIP-seq
MIRT1235280	hsa-miR-4465	CLIP-seq
MIRT2069257	hsa-miR-4467	CLIP-seq
MIRT2069258	hsa-miR-4488	CLIP-seq
MIRT2069259	hsa-miR-4645-5p	CLIP-seq
MIRT1235284	hsa-miR-4660	CLIP-seq
MIRT1235287	hsa-miR-4667-5p	CLIP-seq
MIRT2069260	hsa-miR-4673	CLIP-seq
MIRT1235288	hsa-miR-4685-5p	CLIP-seq
MIRT2069261	hsa-miR-4697-5p	CLIP-seq
MIRT1235290	hsa-miR-4700-5p	CLIP-seq
MIRT2069262	hsa-miR-4715-5p	CLIP-seq
MIRT1235292	hsa-miR-4722-5p	CLIP-seq
MIRT2069263	hsa-miR-4724-5p	CLIP-seq
MIRT1235294	hsa-miR-4726-3p	CLIP-seq
MIRT2069264	hsa-miR-4730	CLIP-seq
MIRT2069265	hsa-miR-4755-3p	CLIP-seq
MIRT2069266	hsa-miR-4758-3p	CLIP-seq
MIRT1235300	hsa-miR-4766-5p	CLIP-seq
MIRT2069267	hsa-miR-4768-3p	CLIP-seq
MIRT1235302	hsa-miR-4784	CLIP-seq
MIRT2069268	hsa-miR-4797-5p	CLIP-seq
MIRT2069269	hsa-miR-484	CLIP-seq
MIRT1235303	hsa-miR-497	CLIP-seq
MIRT1235305	hsa-miR-5047	CLIP-seq
MIRT1235307	hsa-miR-516a-3p	CLIP-seq
MIRT2069270	hsa-miR-548b-3p	CLIP-seq
MIRT2069271	hsa-miR-571	CLIP-seq
MIRT2069272	hsa-miR-574-3p	CLIP-seq
MIRT1235318	hsa-miR-637	CLIP-seq
MIRT2069273	hsa-miR-663	CLIP-seq
MIRT2069274	hsa-miR-744	CLIP-seq
MIRT2069275	hsa-miR-760	CLIP-seq
MIRT1235322	hsa-miR-764	CLIP-seq
MIRT1235323	hsa-miR-765	CLIP-seq
MIRT1235324	hsa-miR-766	CLIP-seq
MIRT2069248	hsa-miR-1182	CLIP-seq
MIRT1235212	hsa-miR-1206	CLIP-seq
MIRT2069249	hsa-miR-1228	CLIP-seq
MIRT2296328	hsa-miR-124	CLIP-seq
MIRT1235215	hsa-miR-125a-3p	CLIP-seq
MIRT1235218	hsa-miR-1281	CLIP-seq
MIRT1235219	hsa-miR-1284	CLIP-seq
MIRT1235222	hsa-miR-1297	CLIP-seq
MIRT2296329	hsa-miR-140-3p	CLIP-seq
MIRT1235226	hsa-miR-1471	CLIP-seq
MIRT1235228	hsa-miR-15a	CLIP-seq
MIRT1235229	hsa-miR-15b	CLIP-seq
MIRT1235230	hsa-miR-16	CLIP-seq
MIRT1235231	hsa-miR-1915	CLIP-seq
MIRT1235232	hsa-miR-195	CLIP-seq
MIRT1235233	hsa-miR-2115	CLIP-seq
MIRT1235234	hsa-miR-26a	CLIP-seq
MIRT1235235	hsa-miR-26b	CLIP-seq
MIRT2069251	hsa-miR-3133	CLIP-seq
MIRT1235239	hsa-miR-3150b-3p	CLIP-seq
MIRT1235241	hsa-miR-3170	CLIP-seq
MIRT1235242	hsa-miR-3176	CLIP-seq
MIRT1235245	hsa-miR-3184	CLIP-seq
MIRT1235248	hsa-miR-323-5p	CLIP-seq
MIRT1235249	hsa-miR-329	CLIP-seq
MIRT2296330	hsa-miR-330-3p	CLIP-seq
MIRT1235250	hsa-miR-331-3p	CLIP-seq
MIRT1235255	hsa-miR-362-3p	CLIP-seq
MIRT1235258	hsa-miR-3665	CLIP-seq
MIRT1235259	hsa-miR-3687	CLIP-seq
MIRT1235261	hsa-miR-3691-3p	CLIP-seq
MIRT1235262	hsa-miR-3714	CLIP-seq
MIRT1235263	hsa-miR-377	CLIP-seq
MIRT1235265	hsa-miR-3922-3p	CLIP-seq
MIRT1235266	hsa-miR-3926	CLIP-seq
MIRT1235267	hsa-miR-3934	CLIP-seq
MIRT2296331	hsa-miR-3974	CLIP-seq
MIRT1235269	hsa-miR-423-5p	CLIP-seq
MIRT1235270	hsa-miR-424	CLIP-seq
MIRT1235272	hsa-miR-4281	CLIP-seq
MIRT1235273	hsa-miR-4286	CLIP-seq
MIRT1235278	hsa-miR-4442	CLIP-seq
MIRT1235279	hsa-miR-4459	CLIP-seq
MIRT1235280	hsa-miR-4465	CLIP-seq
MIRT1235281	hsa-miR-4493	CLIP-seq
MIRT1235282	hsa-miR-4514	CLIP-seq
MIRT2296332	hsa-miR-4640-3p	CLIP-seq
MIRT1235285	hsa-miR-4662a-5p	CLIP-seq
MIRT1235286	hsa-miR-4666-5p	CLIP-seq
MIRT1235287	hsa-miR-4667-5p	CLIP-seq
MIRT1235288	hsa-miR-4685-5p	CLIP-seq
MIRT2296333	hsa-miR-4691-3p	CLIP-seq
MIRT1235289	hsa-miR-4692	CLIP-seq
MIRT1235290	hsa-miR-4700-5p	CLIP-seq
MIRT1235292	hsa-miR-4722-5p	CLIP-seq
MIRT1235294	hsa-miR-4726-3p	CLIP-seq
MIRT1235296	hsa-miR-4736	CLIP-seq
MIRT1235298	hsa-miR-4747-5p	CLIP-seq
MIRT1235299	hsa-miR-4763-5p	CLIP-seq
MIRT2069267	hsa-miR-4768-3p	CLIP-seq
MIRT1235302	hsa-miR-4784	CLIP-seq
MIRT2296334	hsa-miR-493	CLIP-seq
MIRT1235303	hsa-miR-497	CLIP-seq
MIRT2296335	hsa-miR-506	CLIP-seq
MIRT1235307	hsa-miR-516a-3p	CLIP-seq
MIRT1235309	hsa-miR-520d-5p	CLIP-seq
MIRT1235310	hsa-miR-524-5p	CLIP-seq
MIRT2296336	hsa-miR-548an	CLIP-seq
MIRT2069270	hsa-miR-548b-3p	CLIP-seq
MIRT1235314	hsa-miR-548s	CLIP-seq
MIRT1235318	hsa-miR-637	CLIP-seq
MIRT1235322	hsa-miR-764	CLIP-seq
MIRT1235323	hsa-miR-765	CLIP-seq
MIRT2296337	hsa-miR-888	CLIP-seq
MIRT1235212	hsa-miR-1206	CLIP-seq
MIRT1235213	hsa-miR-1226	CLIP-seq
MIRT2296328	hsa-miR-124	CLIP-seq
MIRT1235244	hsa-miR-3182	CLIP-seq
MIRT2296330	hsa-miR-330-3p	CLIP-seq
MIRT1235257	hsa-miR-3660	CLIP-seq
MIRT2296331	hsa-miR-3974	CLIP-seq
MIRT1235271	hsa-miR-4256	CLIP-seq
MIRT1235283	hsa-miR-4526	CLIP-seq
MIRT1235286	hsa-miR-4666-5p	CLIP-seq
MIRT1235295	hsa-miR-4733-3p	CLIP-seq
MIRT2296334	hsa-miR-493	CLIP-seq
MIRT2296335	hsa-miR-506	CLIP-seq
MIRT1235312	hsa-miR-541	CLIP-seq
MIRT2296336	hsa-miR-548an	CLIP-seq
MIRT1235319	hsa-miR-654-5p	CLIP-seq
MIRT2296337	hsa-miR-888	CLIP-seq

Show/Hide all (23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	18593906
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	17270021
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006468	Process	Protein phosphorylation	IDA	18593906
GO:0006915	Process	Apoptotic process	IEA
GO:0007346	Process	Regulation of mitotic cell cycle	IBA
GO:0007346	Process	Regulation of mitotic cell cycle	IMP	17270021
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IBA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	17270021
GO:0061179	Process	Negative regulation of insulin secretion involved in cellular response to glucose stimulus	IEA
GO:0061179	Process	Negative regulation of insulin secretion involved in cellular response to glucose stimulus	ISS
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1904322	Process	Cellular response to forskolin	IEA

MIM	HGNC	e!Ensembl
610580	19310	ENSG00000198355

Q86V86

Protein name

Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)

Protein function

Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which indu

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	40 → 293	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in various tissues, including the heart, brain, lung, kidney, spleen, placenta, skeletal muscle, and peripheral blood leukocytes. Not found or barely expressed in the normal adult endoderm-derived organs such as colon, thymus,

Sequence

MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL

Sequence length

326

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CANNABIS DEPENDENCE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DISORDER OF PHARYNX	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GESTATIONAL DIABETES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HIP	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RESPIRATORY SYSTEM DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TONSILLITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (64)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute pancreatitis	Pancreatitis	BEFREE	31777546		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	BEFREE	17270021		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenoma	Adenoma	BEFREE	17270021		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult T-Cell Lymphoma/Leukemia	T-Cell Lymphoma/Leukemia	BEFREE	28833639		★★★★★ ★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	23760491, 25971209		★★★★★ ★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	21646687, 30805558		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	24818135		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	24818135	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt`s Lymphoma	BEFREE	21646687		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	25921139, 26768612	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	23760491, 25971209	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	37943821	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	25921139		★★★★★ ★☆☆☆☆ Found in Text Mining only
Choriocarcinoma	Choriocarcinoma	BEFREE	28729093		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	15820782, 21763297, 28214201		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	17270021, 21518143, 25071334		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	26768612, 30417983, 30827510		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	17270021, 26768612	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Demyelinating Diseases	Demyelinating Diseases	BEFREE	3878126		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	GWASCAT_DG	29632382		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	24488669	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	22544323, 25817345		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	22544323	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	22544323, 25817345		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hematologic Neoplasms	Hematologic Neoplasms	BEFREE	27826135		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatoblastoma	Hepatoblastoma	BEFREE	29854306, 30898394		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	37910143	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	22078270		★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	21518143, 25071334, 27826617, 29167471, 30898394		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	31671637	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	2387127		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, T-Cell	T-cell leukemia	BEFREE	28833639		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liposarcoma	Liposarcoma	Pubtator	30654529	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	15540201, 16818649, 20101231, 21518143, 21567083, 21981263, 24723452, 25589345, 29069816		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	15540201		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure, Acute	Liver failure	BEFREE	20635403, 31628693		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	15540201, 21567083, 24723452		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	24488669, 26768612	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	21646687		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	31671637	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	24818135		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	25921139		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	16818649, 19154409, 21981263, 23760491, 23845873, 24165482, 24789328, 25071334, 25971209, 26238203, 27016481, 28775772, 31211245		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	27826135		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	31260686		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	21518143, 21981263, 25071334, 27826617, 30802730		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	17270021		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	29370558, 31849942		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	16308470	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	27525970		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12748291, 22558405, 23845873, 24789328, 25971209, 27448973, 27638830, 30417983, 30898394		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	36907773	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	25921139		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	25921139	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	16818649, 19154409, 21981263, 23760491, 23845873, 24165482, 24789328, 25071334, 25971209, 26238203, 27016481, 28775772, 31211245		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	LHGDN	19154409		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	BEFREE	23845873, 25971209, 27638830		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	19154409, 23760491, 25971209, 27638830	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	27826135		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	27826135, 31730483, 33932111	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rectal Carcinoma	Rectal Carcinoma	BEFREE	29167471		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	31260686		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	29879757	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Tuberous Sclerosis	Tuberous Sclerosis	BEFREE	29170467		★★★★★ ★☆☆☆☆ Found in Text Mining only

PIM3 (Pim-3 proto-oncogene, serine/threonine kinase)