Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	402665
Gene name	IgLON family member 5
Gene symbol	IGLON5
Synonyms (NCBI Gene)	-
Chromosome	19
Chromosome location	19q13.41

230

Show/Hide all (230)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018176	hsa-miR-335-5p	Microarray	18185580
MIRT040521	hsa-miR-574-3p	CLASH	23622248
MIRT667929	hsa-miR-5193	HITS-CLIP	23824327
MIRT667928	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT667927	hsa-miR-3183	HITS-CLIP	23824327
MIRT667926	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT667925	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT667924	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT667923	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT667922	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT667921	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT667920	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT667919	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT667918	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT667917	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT667916	hsa-miR-4279	HITS-CLIP	23824327
MIRT667915	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT667914	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT667913	hsa-miR-1281	HITS-CLIP	23824327
MIRT609068	hsa-miR-138-5p	HITS-CLIP	23824327
MIRT609067	hsa-miR-7978	HITS-CLIP	23824327
MIRT609066	hsa-miR-3650	HITS-CLIP	23824327
MIRT551913	hsa-miR-4711-3p	HITS-CLIP	23824327
MIRT551911	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT551908	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT609068	hsa-miR-138-5p	HITS-CLIP	24906430
MIRT609067	hsa-miR-7978	HITS-CLIP	24906430
MIRT609066	hsa-miR-3650	HITS-CLIP	24906430
MIRT551913	hsa-miR-4711-3p	HITS-CLIP	24906430
MIRT551911	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT551908	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT551917	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT551916	hsa-miR-567	PAR-CLIP	21572407
MIRT551915	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT551913	hsa-miR-4711-3p	PAR-CLIP	21572407
MIRT551914	hsa-miR-3911	PAR-CLIP	21572407
MIRT551912	hsa-miR-644a	PAR-CLIP	21572407
MIRT551911	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT551910	hsa-miR-297	PAR-CLIP	21572407
MIRT551909	hsa-miR-147a	PAR-CLIP	21572407
MIRT551908	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT609068	hsa-miR-138-5p	HITS-CLIP	27418678
MIRT551915	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT551915	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT551915	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT551910	hsa-miR-297	HITS-CLIP	27418678
MIRT609066	hsa-miR-3650	HITS-CLIP	27418678
MIRT551913	hsa-miR-4711-3p	HITS-CLIP	27418678
MIRT551913	hsa-miR-4711-3p	HITS-CLIP	27418678
MIRT551913	hsa-miR-4711-3p	HITS-CLIP	27418678
MIRT551917	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT551916	hsa-miR-567	HITS-CLIP	27418678
MIRT551908	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT551908	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT551908	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT551911	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT551911	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT551911	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT609067	hsa-miR-7978	HITS-CLIP	27418678
MIRT667929	hsa-miR-5193	HITS-CLIP	23824327
MIRT667928	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT667927	hsa-miR-3183	HITS-CLIP	23824327
MIRT667926	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT667925	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT667924	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT667923	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT667922	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT667921	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT667920	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT667919	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT667918	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT667917	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT667916	hsa-miR-4279	HITS-CLIP	23824327
MIRT667915	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT667914	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT667913	hsa-miR-1281	HITS-CLIP	23824327
MIRT609068	hsa-miR-138-5p	HITS-CLIP	23824327
MIRT609067	hsa-miR-7978	HITS-CLIP	23824327
MIRT609066	hsa-miR-3650	HITS-CLIP	23824327
MIRT551913	hsa-miR-4711-3p	HITS-CLIP	23824327
MIRT551911	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT551908	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT551917	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT551916	hsa-miR-567	PAR-CLIP	21572407
MIRT551915	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT551913	hsa-miR-4711-3p	PAR-CLIP	21572407
MIRT551914	hsa-miR-3911	PAR-CLIP	21572407
MIRT551912	hsa-miR-644a	PAR-CLIP	21572407
MIRT551911	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT551910	hsa-miR-297	PAR-CLIP	21572407
MIRT551909	hsa-miR-147a	PAR-CLIP	21572407
MIRT551908	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT1062394	hsa-miR-1182	CLIP-seq
MIRT1062395	hsa-miR-1205	CLIP-seq
MIRT1062396	hsa-miR-1207-3p	CLIP-seq
MIRT1062397	hsa-miR-1237	CLIP-seq
MIRT1062398	hsa-miR-1248	CLIP-seq
MIRT1062399	hsa-miR-1266	CLIP-seq
MIRT1062400	hsa-miR-1343	CLIP-seq
MIRT1062401	hsa-miR-147	CLIP-seq
MIRT1062402	hsa-miR-1909	CLIP-seq
MIRT1062403	hsa-miR-1976	CLIP-seq
MIRT1062404	hsa-miR-214	CLIP-seq
MIRT1062405	hsa-miR-2681	CLIP-seq
MIRT1062406	hsa-miR-3122	CLIP-seq
MIRT1062407	hsa-miR-3135b	CLIP-seq
MIRT1062408	hsa-miR-3155	CLIP-seq
MIRT1062409	hsa-miR-3155b	CLIP-seq
MIRT1062410	hsa-miR-3165	CLIP-seq
MIRT1062411	hsa-miR-3192	CLIP-seq
MIRT1062412	hsa-miR-329	CLIP-seq
MIRT1062413	hsa-miR-331-3p	CLIP-seq
MIRT1062414	hsa-miR-342-3p	CLIP-seq
MIRT1062415	hsa-miR-3614-3p	CLIP-seq
MIRT1062416	hsa-miR-3619-5p	CLIP-seq
MIRT1062417	hsa-miR-362-3p	CLIP-seq
MIRT1062418	hsa-miR-362-5p	CLIP-seq
MIRT1062419	hsa-miR-3664-3p	CLIP-seq
MIRT1062420	hsa-miR-3670	CLIP-seq
MIRT1062421	hsa-miR-3689a-3p	CLIP-seq
MIRT1062422	hsa-miR-3689c	CLIP-seq
MIRT1062423	hsa-miR-3689d	CLIP-seq
MIRT1062424	hsa-miR-3690	CLIP-seq
MIRT1062425	hsa-miR-377	CLIP-seq
MIRT1062426	hsa-miR-3913-5p	CLIP-seq
MIRT1062427	hsa-miR-410	CLIP-seq
MIRT1062428	hsa-miR-4284	CLIP-seq
MIRT1062429	hsa-miR-4292	CLIP-seq
MIRT1062430	hsa-miR-4308	CLIP-seq
MIRT1062431	hsa-miR-4313	CLIP-seq
MIRT1062432	hsa-miR-4328	CLIP-seq
MIRT1062433	hsa-miR-4489	CLIP-seq
MIRT1062434	hsa-miR-4518	CLIP-seq
MIRT1062435	hsa-miR-4646-5p	CLIP-seq
MIRT1062436	hsa-miR-4665-3p	CLIP-seq
MIRT1062437	hsa-miR-4705	CLIP-seq
MIRT1062438	hsa-miR-4716-3p	CLIP-seq
MIRT1062439	hsa-miR-4723-5p	CLIP-seq
MIRT1062440	hsa-miR-4725-5p	CLIP-seq
MIRT1062441	hsa-miR-4728-3p	CLIP-seq
MIRT1062442	hsa-miR-4728-5p	CLIP-seq
MIRT1062443	hsa-miR-4731-3p	CLIP-seq
MIRT1062444	hsa-miR-4761-3p	CLIP-seq
MIRT1062445	hsa-miR-4768-5p	CLIP-seq
MIRT1062446	hsa-miR-4785	CLIP-seq
MIRT1062447	hsa-miR-4792	CLIP-seq
MIRT1062448	hsa-miR-4801	CLIP-seq
MIRT1062449	hsa-miR-484	CLIP-seq
MIRT1062450	hsa-miR-490-5p	CLIP-seq
MIRT1062451	hsa-miR-500b	CLIP-seq
MIRT1062452	hsa-miR-501-5p	CLIP-seq
MIRT1062453	hsa-miR-504	CLIP-seq
MIRT1062454	hsa-miR-513a-5p	CLIP-seq
MIRT1062455	hsa-miR-582-5p	CLIP-seq
MIRT1062456	hsa-miR-599	CLIP-seq
MIRT1062457	hsa-miR-634	CLIP-seq
MIRT1062458	hsa-miR-644	CLIP-seq
MIRT1062459	hsa-miR-671-5p	CLIP-seq
MIRT1062460	hsa-miR-7	CLIP-seq
MIRT1062461	hsa-miR-711	CLIP-seq
MIRT1062462	hsa-miR-761	CLIP-seq
MIRT1062405	hsa-miR-2681	CLIP-seq
MIRT1062427	hsa-miR-410	CLIP-seq
MIRT1062432	hsa-miR-4328	CLIP-seq
MIRT1550092	hsa-miR-4684-5p	CLIP-seq
MIRT1062445	hsa-miR-4768-5p	CLIP-seq
MIRT1062450	hsa-miR-490-5p	CLIP-seq
MIRT1062419	hsa-miR-3664-3p	CLIP-seq
MIRT1062444	hsa-miR-4761-3p	CLIP-seq
MIRT2247045	hsa-miR-138	CLIP-seq
MIRT2247046	hsa-miR-4690-3p	CLIP-seq
MIRT2389307	hsa-miR-1913	CLIP-seq
MIRT2389308	hsa-miR-27a	CLIP-seq
MIRT2389309	hsa-miR-27b	CLIP-seq
MIRT1062408	hsa-miR-3155	CLIP-seq
MIRT1062409	hsa-miR-3155b	CLIP-seq
MIRT2389310	hsa-miR-324-3p	CLIP-seq
MIRT1062412	hsa-miR-329	CLIP-seq
MIRT1062414	hsa-miR-342-3p	CLIP-seq
MIRT1062417	hsa-miR-362-3p	CLIP-seq
MIRT2389311	hsa-miR-3692	CLIP-seq
MIRT1062425	hsa-miR-377	CLIP-seq
MIRT1062428	hsa-miR-4284	CLIP-seq
MIRT2389312	hsa-miR-4436b-5p	CLIP-seq
MIRT1062443	hsa-miR-4731-3p	CLIP-seq
MIRT1062448	hsa-miR-4801	CLIP-seq
MIRT1062449	hsa-miR-484	CLIP-seq
MIRT1062454	hsa-miR-513a-5p	CLIP-seq
MIRT2389313	hsa-miR-938	CLIP-seq
MIRT2442262	hsa-miR-136	CLIP-seq
MIRT2442263	hsa-miR-3156-5p	CLIP-seq
MIRT2442264	hsa-miR-4286	CLIP-seq
MIRT2451648	hsa-miR-1273g	CLIP-seq
MIRT2247045	hsa-miR-138	CLIP-seq
MIRT2451649	hsa-miR-149	CLIP-seq
MIRT2451650	hsa-miR-3064-5p	CLIP-seq
MIRT2451651	hsa-miR-320e	CLIP-seq
MIRT2451652	hsa-miR-323-5p	CLIP-seq
MIRT1062424	hsa-miR-3690	CLIP-seq
MIRT1062429	hsa-miR-4292	CLIP-seq
MIRT2451653	hsa-miR-4456	CLIP-seq
MIRT1062435	hsa-miR-4646-5p	CLIP-seq
MIRT2451654	hsa-miR-4700-3p	CLIP-seq
MIRT1062440	hsa-miR-4725-5p	CLIP-seq
MIRT2451655	hsa-miR-4794	CLIP-seq
MIRT1062453	hsa-miR-504	CLIP-seq
MIRT2451656	hsa-miR-548v	CLIP-seq
MIRT2451657	hsa-miR-563	CLIP-seq
MIRT1062460	hsa-miR-7	CLIP-seq
MIRT1062461	hsa-miR-711	CLIP-seq
MIRT2451658	hsa-miR-876-3p	CLIP-seq
MIRT2451648	hsa-miR-1273g	CLIP-seq
MIRT2247045	hsa-miR-138	CLIP-seq
MIRT2451649	hsa-miR-149	CLIP-seq
MIRT2451650	hsa-miR-3064-5p	CLIP-seq
MIRT2451651	hsa-miR-320e	CLIP-seq
MIRT2451652	hsa-miR-323-5p	CLIP-seq
MIRT1062424	hsa-miR-3690	CLIP-seq
MIRT1062429	hsa-miR-4292	CLIP-seq
MIRT2451653	hsa-miR-4456	CLIP-seq
MIRT1062435	hsa-miR-4646-5p	CLIP-seq
MIRT2451654	hsa-miR-4700-3p	CLIP-seq
MIRT1062440	hsa-miR-4725-5p	CLIP-seq
MIRT2451655	hsa-miR-4794	CLIP-seq
MIRT1062453	hsa-miR-504	CLIP-seq
MIRT2451656	hsa-miR-548v	CLIP-seq
MIRT2451657	hsa-miR-563	CLIP-seq
MIRT1062460	hsa-miR-7	CLIP-seq
MIRT1062461	hsa-miR-711	CLIP-seq
MIRT2451658	hsa-miR-876-3p	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence
GO:0005576	Component	Extracellular region	IEA
GO:0008038	Process	Neuron recognition	IEA
GO:0050885	Process	Neuromuscular process controlling balance	IEA
GO:0061744	Process	Motor behavior	IEA

MIM	HGNC	e!Ensembl
618861	34550	ENSG00000142549

A6NGN9

Protein name

IgLON family member 5

PDB

6DLD , 6DLE

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00047	ig	37 → 127	Immunoglobulin domain	Domain
PF13927	Ig_3	134 → 199		Domain
PF13927	Ig_3	217 → 295		Domain

Sequence

MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHV
TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP
YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEIL
EISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEA
MAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS
SASMRLLRPGSLENSAPRPPGLLALLSALGWLWWRM

Sequence length

336

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OROFACIAL CLEFT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (22)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
AICARDI-GOUTIERES SYNDROME	Aicardi Goutieres Syndrome	BEFREE	27262149		★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic lateral sclerosis	Pubtator	35857139	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases of the Nervous System	Autoimmune nervous system disorder	Pubtator	37217310	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Diseases	Brain disease	Pubtator	33731000	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Stem Neoplasms	Brain stem neoplasms	Pubtator	31454761	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bulbar Palsy Progressive	Bulbar palsy	Pubtator	28381508	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chorea	Chorea	Pubtator	28381508	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chromosomal Instability	Chromosomal instability	Pubtator	31454761	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognition disorder	Pubtator	28381508	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34497681	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	BEFREE	28778439, 29867738		★★★★★ ★☆☆☆☆ Found in Text Mining only
Encephalitis	Encephalitis	Pubtator	37217310	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Encephalopathies	Epileptic encephalopathy	BEFREE	28778439		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperkinesis	Hyperkinesia	Pubtator	35857139	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Motor Neuron Disease	Motor neuron disease	Pubtator	35857139	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Movement Disorders	Movement Disorders	BEFREE	31096519		★★★★★ ★☆☆☆☆ Found in Text Mining only
nervous system disorder	Nervous System Disorder	BEFREE	27586161, 29936617		★★★★★ ★☆☆☆☆ Found in Text Mining only
Progressive supranuclear palsy	Progressive Supranuclear Palsy	BEFREE	28381508, 29867738		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sleep Apnea Syndromes	Sleep apnea	Pubtator	28381508	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Sleep Disorders	Sleep Disorders	BEFREE	28381508, 28878050, 29796717		★★★★★ ★☆☆☆☆ Found in Text Mining only
Supranuclear Palsy Progressive	Progressive supranuclear palsy	Pubtator	28381508, 34659261, 40132252	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Tauopathies	Tauopathies	BEFREE	27262149, 28550263, 29053777		★★★★★ ★☆☆☆☆ Found in Text Mining only

IGLON5 (IgLON family member 5)