TMEM215 (transmembrane protein 215)

Gene

• Entrez ID: 401498
• Gene name: Transmembrane protein 215
• Gene symbol: TMEM215
• Synonyms (NCBI Gene): -
• Chromosome: 9
• Chromosome location: 9p21.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT446495	hsa-miR-4635	PAR-CLIP	22291592
MIRT446493	hsa-miR-7158-3p	PAR-CLIP	22291592
MIRT446492	hsa-miR-203b-3p	PAR-CLIP	22291592
MIRT446491	hsa-miR-7641	PAR-CLIP	22291592
MIRT446494	hsa-miR-5580-3p	PAR-CLIP	22100165
MIRT446495	hsa-miR-4635	PAR-CLIP	22100165
MIRT446493	hsa-miR-7158-3p	PAR-CLIP	22100165
MIRT446492	hsa-miR-203b-3p	PAR-CLIP	22100165
MIRT446491	hsa-miR-7641	PAR-CLIP	22100165
MIRT446495	hsa-miR-4635	PAR-CLIP	22291592
MIRT446493	hsa-miR-7158-3p	PAR-CLIP	22291592
MIRT446492	hsa-miR-203b-3p	PAR-CLIP	22291592
MIRT446491	hsa-miR-7641	PAR-CLIP	22291592
MIRT446494	hsa-miR-5580-3p	PAR-CLIP	22100165
MIRT446495	hsa-miR-4635	PAR-CLIP	22100165
MIRT446493	hsa-miR-7158-3p	PAR-CLIP	22100165
MIRT446492	hsa-miR-203b-3p	PAR-CLIP	22100165
MIRT446491	hsa-miR-7641	PAR-CLIP	22100165
MIRT1435453	hsa-miR-1202	CLIP-seq
MIRT1435454	hsa-miR-125a-3p	CLIP-seq
MIRT1435455	hsa-miR-1305	CLIP-seq
MIRT1435456	hsa-miR-191	CLIP-seq
MIRT1435457	hsa-miR-3194-5p	CLIP-seq
MIRT1435458	hsa-miR-3622b-5p	CLIP-seq
MIRT1435459	hsa-miR-3934	CLIP-seq
MIRT1435460	hsa-miR-3942-5p	CLIP-seq
MIRT1435461	hsa-miR-3972	CLIP-seq
MIRT1435462	hsa-miR-410	CLIP-seq
MIRT1435463	hsa-miR-4272	CLIP-seq
MIRT1435464	hsa-miR-4496	CLIP-seq
MIRT1435465	hsa-miR-4499	CLIP-seq
MIRT1435466	hsa-miR-4513	CLIP-seq
MIRT1435467	hsa-miR-4703-5p	CLIP-seq
MIRT1435468	hsa-miR-4709-3p	CLIP-seq
MIRT1435469	hsa-miR-4797-5p	CLIP-seq
MIRT1435470	hsa-miR-4803	CLIP-seq
MIRT1435471	hsa-miR-510	CLIP-seq
MIRT1435472	hsa-miR-764	CLIP-seq
MIRT1435465	hsa-miR-4499	CLIP-seq
MIRT1435466	hsa-miR-4513	CLIP-seq
MIRT1435468	hsa-miR-4709-3p	CLIP-seq
MIRT1435465	hsa-miR-4499	CLIP-seq
MIRT1435466	hsa-miR-4513	CLIP-seq
MIRT1435468	hsa-miR-4709-3p	CLIP-seq
MIRT2130478	hsa-miR-3124-3p	CLIP-seq
MIRT2130479	hsa-miR-3183	CLIP-seq
MIRT2130480	hsa-miR-339-5p	CLIP-seq
MIRT2130481	hsa-miR-3685	CLIP-seq
MIRT2130482	hsa-miR-384	CLIP-seq
MIRT2130483	hsa-miR-4291	CLIP-seq
MIRT2130484	hsa-miR-4328	CLIP-seq
MIRT2130485	hsa-miR-4428	CLIP-seq
MIRT2130486	hsa-miR-4446-5p	CLIP-seq
MIRT2130487	hsa-miR-4457	CLIP-seq
MIRT2130488	hsa-miR-4480	CLIP-seq
MIRT1435465	hsa-miR-4499	CLIP-seq
MIRT1435466	hsa-miR-4513	CLIP-seq
MIRT1435468	hsa-miR-4709-3p	CLIP-seq
MIRT2130489	hsa-miR-4723-3p	CLIP-seq
MIRT2130490	hsa-miR-4727-5p	CLIP-seq
MIRT2130491	hsa-miR-4755-5p	CLIP-seq
MIRT2130492	hsa-miR-4772-3p	CLIP-seq
MIRT2130493	hsa-miR-520d-5p	CLIP-seq
MIRT2130494	hsa-miR-524-5p	CLIP-seq
MIRT2130495	hsa-miR-544	CLIP-seq
MIRT2130496	hsa-miR-545	CLIP-seq
MIRT2130497	hsa-miR-670	CLIP-seq
MIRT2351816	hsa-miR-1238	CLIP-seq
MIRT2351817	hsa-miR-15a	CLIP-seq
MIRT2351818	hsa-miR-15b	CLIP-seq
MIRT2351819	hsa-miR-16	CLIP-seq
MIRT2351820	hsa-miR-195	CLIP-seq
MIRT2351821	hsa-miR-214	CLIP-seq
MIRT2351822	hsa-miR-3185	CLIP-seq
MIRT2351823	hsa-miR-3619-5p	CLIP-seq
MIRT2351824	hsa-miR-424	CLIP-seq
MIRT2130483	hsa-miR-4291	CLIP-seq
MIRT2351825	hsa-miR-4293	CLIP-seq
MIRT2351826	hsa-miR-4311	CLIP-seq
MIRT2351827	hsa-miR-4436b-3p	CLIP-seq
MIRT2351828	hsa-miR-4539	CLIP-seq
MIRT2351829	hsa-miR-494	CLIP-seq
MIRT2351830	hsa-miR-497	CLIP-seq
MIRT2351831	hsa-miR-539	CLIP-seq
MIRT2130496	hsa-miR-545	CLIP-seq
MIRT2351832	hsa-miR-548p	CLIP-seq
MIRT2351833	hsa-miR-7	CLIP-seq
MIRT2351834	hsa-miR-761	CLIP-seq
MIRT2351835	hsa-miR-922	CLIP-seq
MIRT2130488	hsa-miR-4480	CLIP-seq
MIRT1435465	hsa-miR-4499	CLIP-seq
MIRT1435466	hsa-miR-4513	CLIP-seq
MIRT1435468	hsa-miR-4709-3p	CLIP-seq
MIRT2130492	hsa-miR-4772-3p	CLIP-seq
MIRT2461808	hsa-miR-186	CLIP-seq
MIRT2461809	hsa-miR-2467-3p	CLIP-seq
MIRT2461810	hsa-miR-2964a-3p	CLIP-seq
MIRT2461811	hsa-miR-3653	CLIP-seq
MIRT2461812	hsa-miR-3658	CLIP-seq
MIRT2461813	hsa-miR-3678-3p	CLIP-seq
MIRT2461814	hsa-miR-571	CLIP-seq
MIRT2645525	hsa-miR-2276	CLIP-seq
MIRT2645526	hsa-miR-3647-3p	CLIP-seq
MIRT2645527	hsa-miR-3942-3p	CLIP-seq
MIRT2645528	hsa-miR-4778-3p	CLIP-seq
MIRT2645529	hsa-miR-4790-3p	CLIP-seq
MIRT2645530	hsa-miR-554	CLIP-seq
MIRT2645525	hsa-miR-2276	CLIP-seq
MIRT2645526	hsa-miR-3647-3p	CLIP-seq
MIRT2645527	hsa-miR-3942-3p	CLIP-seq
MIRT2645528	hsa-miR-4778-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IEA
GO:0002040	Process	Sprouting angiogenesis	IEA
GO:0016020	Component	Membrane	IEA
GO:0046671	Process	Negative regulation of retinal cell programmed cell death	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q68D42
• Protein name: Transmembrane protein 215
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15746	TMEM215	1 → 235	TMEM215 family	Family

• Sequence:

  MRPDDINPRTGLVVALVSVFLVFGFMFTVSGMKGETLGNIPLLAIGPAICLPGIAAIALA
  RKTEGCTKWPENELLWVRKLPCFRKPKDKEVVELLRTPSDLESGKGSSDELAKKAGLRGK
  PPPQSQGEVSVASSINSPTPTEEGECQSLVQNGHQEETSRYLDGYCPSGSSLTYSALDVK
  CSARDRSECPEPEDSIFFVPQDSIIVCSYKQNSPYDRYCCYINQIQGRWDHETIV

• Sequence length: 235

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EARLY-ONSET ALZHEIMERS DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LATE-ONSET ALZHEIMER'S DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	40001597	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30370660		★☆☆☆☆ Found in Text Mining only