ARHGAP5 (Rho GTPase activating protein 5)

Gene

• Entrez ID: 394
• Gene name: Rho GTPase activating protein 5
• Gene symbol: ARHGAP5
• Synonyms (NCBI Gene): GFI2, RhoGAP5, p190-B, p190BRhoGAP
• Chromosome: 14
• Chromosome location: 14q12
• Summary: Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by R

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT016745	hsa-miR-335-5p	Microarray	18185580
MIRT021887	hsa-miR-128-3p	Microarray	17612493
MIRT050904	hsa-miR-17-5p	CLASH	23622248
MIRT048327	hsa-miR-106a-5p	CLASH	23622248
MIRT053295	hsa-miR-486-5p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	23474761
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT438172	hsa-miR-494-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	24316134
MIRT441200	hsa-miR-493-3p	HITS-CLIP	24374217
MIRT441199	hsa-miR-493-5p	HITS-CLIP	24374217
MIRT441198	hsa-miR-770-5p	HITS-CLIP	24374217
MIRT441200	hsa-miR-493-3p	HITS-CLIP	24374217
MIRT441199	hsa-miR-493-5p	HITS-CLIP	24374217
MIRT441198	hsa-miR-770-5p	HITS-CLIP	24374217
MIRT794922	hsa-miR-1206	CLIP-seq
MIRT794923	hsa-miR-1261	CLIP-seq
MIRT794924	hsa-miR-140-3p	CLIP-seq
MIRT794925	hsa-miR-145	CLIP-seq
MIRT794926	hsa-miR-15a	CLIP-seq
MIRT794927	hsa-miR-15b	CLIP-seq
MIRT794928	hsa-miR-16	CLIP-seq
MIRT794929	hsa-miR-182	CLIP-seq
MIRT794930	hsa-miR-18a	CLIP-seq
MIRT794931	hsa-miR-18b	CLIP-seq
MIRT794932	hsa-miR-194	CLIP-seq
MIRT794933	hsa-miR-195	CLIP-seq
MIRT794934	hsa-miR-199a-3p	CLIP-seq
MIRT794935	hsa-miR-199b-3p	CLIP-seq
MIRT794936	hsa-miR-219-2-3p	CLIP-seq
MIRT794937	hsa-miR-2964a-3p	CLIP-seq
MIRT794938	hsa-miR-3129-5p	CLIP-seq
MIRT794939	hsa-miR-3145-3p	CLIP-seq
MIRT794940	hsa-miR-3157-5p	CLIP-seq
MIRT794941	hsa-miR-3201	CLIP-seq
MIRT794942	hsa-miR-338-5p	CLIP-seq
MIRT794943	hsa-miR-3607-3p	CLIP-seq
MIRT794944	hsa-miR-3613-3p	CLIP-seq
MIRT794945	hsa-miR-3619-3p	CLIP-seq
MIRT794946	hsa-miR-3647-3p	CLIP-seq
MIRT794947	hsa-miR-3653	CLIP-seq
MIRT794948	hsa-miR-3658	CLIP-seq
MIRT794949	hsa-miR-3692	CLIP-seq
MIRT794950	hsa-miR-369-3p	CLIP-seq
MIRT794951	hsa-miR-371b-5p	CLIP-seq
MIRT794952	hsa-miR-374a	CLIP-seq
MIRT794953	hsa-miR-374b	CLIP-seq
MIRT794954	hsa-miR-421	CLIP-seq
MIRT794955	hsa-miR-424	CLIP-seq
MIRT794956	hsa-miR-4274	CLIP-seq
MIRT794957	hsa-miR-4276	CLIP-seq
MIRT794958	hsa-miR-4282	CLIP-seq
MIRT794959	hsa-miR-4293	CLIP-seq
MIRT794960	hsa-miR-4302	CLIP-seq
MIRT794961	hsa-miR-4427	CLIP-seq
MIRT794962	hsa-miR-4470	CLIP-seq
MIRT794963	hsa-miR-4477b	CLIP-seq
MIRT794964	hsa-miR-4494	CLIP-seq
MIRT794965	hsa-miR-4499	CLIP-seq
MIRT794966	hsa-miR-4513	CLIP-seq
MIRT794967	hsa-miR-4528	CLIP-seq
MIRT794968	hsa-miR-4640-3p	CLIP-seq
MIRT794969	hsa-miR-4662a-3p	CLIP-seq
MIRT794970	hsa-miR-4666-5p	CLIP-seq
MIRT794971	hsa-miR-4670-3p	CLIP-seq
MIRT794972	hsa-miR-4680-3p	CLIP-seq
MIRT794973	hsa-miR-4691-3p	CLIP-seq
MIRT794974	hsa-miR-4699-3p	CLIP-seq
MIRT794975	hsa-miR-4704-3p	CLIP-seq
MIRT794976	hsa-miR-4709-5p	CLIP-seq
MIRT794977	hsa-miR-4712-5p	CLIP-seq
MIRT794978	hsa-miR-4719	CLIP-seq
MIRT794979	hsa-miR-4733-5p	CLIP-seq
MIRT794980	hsa-miR-4735-3p	CLIP-seq
MIRT794981	hsa-miR-4757-5p	CLIP-seq
MIRT794982	hsa-miR-4776-5p	CLIP-seq
MIRT794983	hsa-miR-4791	CLIP-seq
MIRT794984	hsa-miR-4797-3p	CLIP-seq
MIRT794985	hsa-miR-495	CLIP-seq
MIRT794986	hsa-miR-497	CLIP-seq
MIRT794987	hsa-miR-499-3p	CLIP-seq
MIRT794988	hsa-miR-499a-3p	CLIP-seq
MIRT794989	hsa-miR-500a	CLIP-seq
MIRT794990	hsa-miR-501-5p	CLIP-seq
MIRT794991	hsa-miR-542-3p	CLIP-seq
MIRT794992	hsa-miR-548c-3p	CLIP-seq
MIRT794993	hsa-miR-548g	CLIP-seq
MIRT794994	hsa-miR-548u	CLIP-seq
MIRT794995	hsa-miR-549	CLIP-seq
MIRT794996	hsa-miR-580	CLIP-seq
MIRT794997	hsa-miR-590-3p	CLIP-seq
MIRT794998	hsa-miR-596	CLIP-seq
MIRT794999	hsa-miR-659	CLIP-seq
MIRT795000	hsa-miR-936	CLIP-seq
MIRT795001	hsa-miR-944	CLIP-seq
MIRT795002	hsa-miR-101	CLIP-seq
MIRT795003	hsa-miR-144	CLIP-seq
MIRT795004	hsa-miR-3163	CLIP-seq
MIRT795005	hsa-miR-374c	CLIP-seq
MIRT795006	hsa-miR-3925-5p	CLIP-seq
MIRT795007	hsa-miR-412	CLIP-seq
MIRT795008	hsa-miR-4311	CLIP-seq
MIRT795009	hsa-miR-4698	CLIP-seq
MIRT795010	hsa-miR-4773	CLIP-seq
MIRT795011	hsa-miR-4774-5p	CLIP-seq
MIRT794985	hsa-miR-495	CLIP-seq
MIRT794993	hsa-miR-548g	CLIP-seq
MIRT795012	hsa-miR-582-3p	CLIP-seq
MIRT795013	hsa-miR-655	CLIP-seq
MIRT1545505	hsa-miR-103a	CLIP-seq
MIRT1545506	hsa-miR-107	CLIP-seq
MIRT1545507	hsa-miR-4775	CLIP-seq
MIRT1545508	hsa-miR-586	CLIP-seq
MIRT1545509	hsa-miR-186	CLIP-seq
MIRT1545510	hsa-miR-494	CLIP-seq
MIRT1545507	hsa-miR-4775	CLIP-seq
MIRT1934728	hsa-miR-23a	CLIP-seq
MIRT1934729	hsa-miR-23b	CLIP-seq
MIRT1934730	hsa-miR-23c	CLIP-seq
MIRT1934731	hsa-miR-3074-5p	CLIP-seq
MIRT1934732	hsa-miR-3119	CLIP-seq
MIRT1934733	hsa-miR-3140-3p	CLIP-seq
MIRT1934734	hsa-miR-3155	CLIP-seq
MIRT1934735	hsa-miR-3155b	CLIP-seq
MIRT1934736	hsa-miR-320a	CLIP-seq
MIRT1934737	hsa-miR-320b	CLIP-seq
MIRT1934738	hsa-miR-320c	CLIP-seq
MIRT1934739	hsa-miR-320d	CLIP-seq
MIRT794942	hsa-miR-338-5p	CLIP-seq
MIRT1934740	hsa-miR-3545-3p	CLIP-seq
MIRT794946	hsa-miR-3647-3p	CLIP-seq
MIRT1934741	hsa-miR-3672	CLIP-seq
MIRT1934742	hsa-miR-3680	CLIP-seq
MIRT794949	hsa-miR-3692	CLIP-seq
MIRT1934743	hsa-miR-376c	CLIP-seq
MIRT1934744	hsa-miR-4429	CLIP-seq
MIRT1934745	hsa-miR-4517	CLIP-seq
MIRT794974	hsa-miR-4699-3p	CLIP-seq
MIRT1934746	hsa-miR-4712-3p	CLIP-seq
MIRT1934747	hsa-miR-4766-5p	CLIP-seq
MIRT795011	hsa-miR-4774-5p	CLIP-seq
MIRT1545507	hsa-miR-4775	CLIP-seq
MIRT1934748	hsa-miR-484	CLIP-seq
MIRT1934749	hsa-miR-513a-3p	CLIP-seq
MIRT794992	hsa-miR-548c-3p	CLIP-seq
MIRT794994	hsa-miR-548u	CLIP-seq
MIRT1934750	hsa-miR-579	CLIP-seq
MIRT794997	hsa-miR-590-3p	CLIP-seq
MIRT795001	hsa-miR-944	CLIP-seq
MIRT795002	hsa-miR-101	CLIP-seq
MIRT1545505	hsa-miR-103a	CLIP-seq
MIRT2174460	hsa-miR-106a	CLIP-seq
MIRT2174461	hsa-miR-106b	CLIP-seq
MIRT1545506	hsa-miR-107	CLIP-seq
MIRT2174462	hsa-miR-1183	CLIP-seq
MIRT2174463	hsa-miR-1205	CLIP-seq
MIRT794922	hsa-miR-1206	CLIP-seq
MIRT2174464	hsa-miR-1284	CLIP-seq
MIRT795003	hsa-miR-144	CLIP-seq
MIRT794926	hsa-miR-15a	CLIP-seq
MIRT794927	hsa-miR-15b	CLIP-seq
MIRT794928	hsa-miR-16	CLIP-seq
MIRT2174465	hsa-miR-17	CLIP-seq
MIRT794932	hsa-miR-194	CLIP-seq
MIRT794933	hsa-miR-195	CLIP-seq
MIRT2174466	hsa-miR-200b	CLIP-seq
MIRT2174467	hsa-miR-200c	CLIP-seq
MIRT2174468	hsa-miR-2052	CLIP-seq
MIRT2174469	hsa-miR-2054	CLIP-seq
MIRT2174470	hsa-miR-20a	CLIP-seq
MIRT2174471	hsa-miR-20b	CLIP-seq
MIRT2174472	hsa-miR-217	CLIP-seq
MIRT2174473	hsa-miR-219-1-3p	CLIP-seq
MIRT2174474	hsa-miR-223	CLIP-seq
MIRT2174475	hsa-miR-2355-3p	CLIP-seq
MIRT2174476	hsa-miR-2355-5p	CLIP-seq
MIRT1934728	hsa-miR-23a	CLIP-seq
MIRT1934729	hsa-miR-23b	CLIP-seq
MIRT1934730	hsa-miR-23c	CLIP-seq
MIRT2174477	hsa-miR-3064-3p	CLIP-seq
MIRT1934731	hsa-miR-3074-5p	CLIP-seq
MIRT2174478	hsa-miR-3121-5p	CLIP-seq
MIRT1934733	hsa-miR-3140-3p	CLIP-seq
MIRT794939	hsa-miR-3145-3p	CLIP-seq
MIRT2174479	hsa-miR-3145-5p	CLIP-seq
MIRT794940	hsa-miR-3157-5p	CLIP-seq
MIRT795004	hsa-miR-3163	CLIP-seq
MIRT1934736	hsa-miR-320a	CLIP-seq
MIRT1934737	hsa-miR-320b	CLIP-seq
MIRT1934738	hsa-miR-320c	CLIP-seq
MIRT1934739	hsa-miR-320d	CLIP-seq
MIRT2174480	hsa-miR-323-3p	CLIP-seq
MIRT2174481	hsa-miR-331-5p	CLIP-seq
MIRT794942	hsa-miR-338-5p	CLIP-seq
MIRT1934740	hsa-miR-3545-3p	CLIP-seq
MIRT794944	hsa-miR-3613-3p	CLIP-seq
MIRT2174482	hsa-miR-362-5p	CLIP-seq
MIRT794946	hsa-miR-3647-3p	CLIP-seq
MIRT2174483	hsa-miR-3662	CLIP-seq
MIRT2174484	hsa-miR-3665	CLIP-seq
MIRT2174485	hsa-miR-3671	CLIP-seq
MIRT794949	hsa-miR-3692	CLIP-seq
MIRT794950	hsa-miR-369-3p	CLIP-seq
MIRT794951	hsa-miR-371b-5p	CLIP-seq
MIRT794952	hsa-miR-374a	CLIP-seq
MIRT794953	hsa-miR-374b	CLIP-seq
MIRT795005	hsa-miR-374c	CLIP-seq
MIRT1934743	hsa-miR-376c	CLIP-seq
MIRT2174486	hsa-miR-382	CLIP-seq
MIRT795006	hsa-miR-3925-5p	CLIP-seq
MIRT2174487	hsa-miR-3973	CLIP-seq
MIRT795007	hsa-miR-412	CLIP-seq
MIRT794954	hsa-miR-421	CLIP-seq
MIRT794955	hsa-miR-424	CLIP-seq
MIRT794956	hsa-miR-4274	CLIP-seq
MIRT794957	hsa-miR-4276	CLIP-seq
MIRT794958	hsa-miR-4282	CLIP-seq
MIRT2174488	hsa-miR-429	CLIP-seq
MIRT794960	hsa-miR-4302	CLIP-seq
MIRT795008	hsa-miR-4311	CLIP-seq
MIRT2174489	hsa-miR-4328	CLIP-seq
MIRT2174490	hsa-miR-4418	CLIP-seq
MIRT2174491	hsa-miR-4420	CLIP-seq
MIRT1934744	hsa-miR-4429	CLIP-seq
MIRT2174492	hsa-miR-448	CLIP-seq
MIRT2174493	hsa-miR-4490	CLIP-seq
MIRT794964	hsa-miR-4494	CLIP-seq
MIRT794965	hsa-miR-4499	CLIP-seq
MIRT2174494	hsa-miR-4504	CLIP-seq
MIRT2174495	hsa-miR-450b-5p	CLIP-seq
MIRT2174496	hsa-miR-4637	CLIP-seq
MIRT794968	hsa-miR-4640-3p	CLIP-seq
MIRT2174497	hsa-miR-4646-3p	CLIP-seq
MIRT794969	hsa-miR-4662a-3p	CLIP-seq
MIRT794970	hsa-miR-4666-5p	CLIP-seq
MIRT794971	hsa-miR-4670-3p	CLIP-seq
MIRT2174498	hsa-miR-4678	CLIP-seq
MIRT794973	hsa-miR-4691-3p	CLIP-seq
MIRT2174499	hsa-miR-4693-5p	CLIP-seq
MIRT2174500	hsa-miR-4697-3p	CLIP-seq
MIRT795009	hsa-miR-4698	CLIP-seq
MIRT794974	hsa-miR-4699-3p	CLIP-seq
MIRT794975	hsa-miR-4704-3p	CLIP-seq
MIRT794976	hsa-miR-4709-5p	CLIP-seq
MIRT2174501	hsa-miR-4715-3p	CLIP-seq
MIRT2174502	hsa-miR-4729	CLIP-seq
MIRT794979	hsa-miR-4733-5p	CLIP-seq
MIRT2174503	hsa-miR-4753-3p	CLIP-seq
MIRT795010	hsa-miR-4773	CLIP-seq
MIRT795011	hsa-miR-4774-5p	CLIP-seq
MIRT1545507	hsa-miR-4775	CLIP-seq
MIRT2174504	hsa-miR-4777-5p	CLIP-seq
MIRT2174505	hsa-miR-4793-5p	CLIP-seq
MIRT2174506	hsa-miR-4796-5p	CLIP-seq
MIRT2174507	hsa-miR-490-5p	CLIP-seq
MIRT794985	hsa-miR-495	CLIP-seq
MIRT794986	hsa-miR-497	CLIP-seq
MIRT794987	hsa-miR-499-3p	CLIP-seq
MIRT794988	hsa-miR-499a-3p	CLIP-seq
MIRT2174508	hsa-miR-500b	CLIP-seq
MIRT794990	hsa-miR-501-5p	CLIP-seq
MIRT2174509	hsa-miR-507	CLIP-seq
MIRT2174510	hsa-miR-509-3-5p	CLIP-seq
MIRT2174511	hsa-miR-509-5p	CLIP-seq
MIRT2174512	hsa-miR-513b	CLIP-seq
MIRT2174513	hsa-miR-519a	CLIP-seq
MIRT2174514	hsa-miR-519b-3p	CLIP-seq
MIRT2174515	hsa-miR-519c-3p	CLIP-seq
MIRT2174516	hsa-miR-519d	CLIP-seq
MIRT794992	hsa-miR-548c-3p	CLIP-seq
MIRT794993	hsa-miR-548g	CLIP-seq
MIRT2174517	hsa-miR-548l	CLIP-seq
MIRT2174518	hsa-miR-548t	CLIP-seq
MIRT794994	hsa-miR-548u	CLIP-seq
MIRT794995	hsa-miR-549	CLIP-seq
MIRT2174519	hsa-miR-553	CLIP-seq
MIRT2174520	hsa-miR-556-3p	CLIP-seq
MIRT2174521	hsa-miR-557	CLIP-seq
MIRT2174522	hsa-miR-571	CLIP-seq
MIRT795012	hsa-miR-582-3p	CLIP-seq
MIRT794997	hsa-miR-590-3p	CLIP-seq
MIRT2174523	hsa-miR-606	CLIP-seq
MIRT2174524	hsa-miR-607	CLIP-seq
MIRT2174525	hsa-miR-646	CLIP-seq
MIRT795013	hsa-miR-655	CLIP-seq
MIRT2174526	hsa-miR-657	CLIP-seq
MIRT794999	hsa-miR-659	CLIP-seq
MIRT2174527	hsa-miR-888	CLIP-seq
MIRT2174528	hsa-miR-93	CLIP-seq
MIRT795001	hsa-miR-944	CLIP-seq
MIRT1545505	hsa-miR-103a	CLIP-seq
MIRT1545506	hsa-miR-107	CLIP-seq
MIRT2384424	hsa-miR-1184	CLIP-seq
MIRT2174464	hsa-miR-1284	CLIP-seq
MIRT2174472	hsa-miR-217	CLIP-seq
MIRT1934733	hsa-miR-3140-3p	CLIP-seq
MIRT1934736	hsa-miR-320a	CLIP-seq
MIRT1934737	hsa-miR-320b	CLIP-seq
MIRT1934738	hsa-miR-320c	CLIP-seq
MIRT1934739	hsa-miR-320d	CLIP-seq
MIRT794946	hsa-miR-3647-3p	CLIP-seq
MIRT795008	hsa-miR-4311	CLIP-seq
MIRT2174490	hsa-miR-4418	CLIP-seq
MIRT1934744	hsa-miR-4429	CLIP-seq
MIRT794974	hsa-miR-4699-3p	CLIP-seq
MIRT2174505	hsa-miR-4793-5p	CLIP-seq
MIRT2174506	hsa-miR-4796-5p	CLIP-seq
MIRT2174510	hsa-miR-509-3-5p	CLIP-seq
MIRT2174511	hsa-miR-509-5p	CLIP-seq
MIRT794994	hsa-miR-548u	CLIP-seq
MIRT2174475	hsa-miR-2355-3p	CLIP-seq
MIRT1934733	hsa-miR-3140-3p	CLIP-seq
MIRT795004	hsa-miR-3163	CLIP-seq
MIRT795006	hsa-miR-3925-5p	CLIP-seq
MIRT795008	hsa-miR-4311	CLIP-seq
MIRT2174497	hsa-miR-4646-3p	CLIP-seq
MIRT2426420	hsa-miR-4724-5p	CLIP-seq
MIRT794979	hsa-miR-4733-5p	CLIP-seq
MIRT794981	hsa-miR-4757-5p	CLIP-seq
MIRT795010	hsa-miR-4773	CLIP-seq
MIRT2174504	hsa-miR-4777-5p	CLIP-seq
MIRT1545510	hsa-miR-494	CLIP-seq
MIRT794993	hsa-miR-548g	CLIP-seq
MIRT2174524	hsa-miR-607	CLIP-seq
MIRT794995	hsa-miR-549	CLIP-seq
MIRT2443922	hsa-miR-1185	CLIP-seq
MIRT2443923	hsa-miR-1197	CLIP-seq
MIRT2443924	hsa-miR-1272	CLIP-seq
MIRT2443925	hsa-miR-3605-5p	CLIP-seq
MIRT2443926	hsa-miR-3679-5p	CLIP-seq
MIRT2478011	hsa-miR-137	CLIP-seq
MIRT2478012	hsa-miR-188-5p	CLIP-seq
MIRT2174474	hsa-miR-223	CLIP-seq
MIRT2174475	hsa-miR-2355-3p	CLIP-seq
MIRT2478013	hsa-miR-3121-3p	CLIP-seq
MIRT2174478	hsa-miR-3121-5p	CLIP-seq
MIRT1934733	hsa-miR-3140-3p	CLIP-seq
MIRT794940	hsa-miR-3157-5p	CLIP-seq
MIRT2478014	hsa-miR-3189-3p	CLIP-seq
MIRT1934736	hsa-miR-320a	CLIP-seq
MIRT1934737	hsa-miR-320b	CLIP-seq
MIRT1934738	hsa-miR-320c	CLIP-seq
MIRT1934739	hsa-miR-320d	CLIP-seq
MIRT2174481	hsa-miR-331-5p	CLIP-seq
MIRT2478015	hsa-miR-3606	CLIP-seq
MIRT2174482	hsa-miR-362-5p	CLIP-seq
MIRT794947	hsa-miR-3653	CLIP-seq
MIRT794948	hsa-miR-3658	CLIP-seq
MIRT2174485	hsa-miR-3671	CLIP-seq
MIRT1934742	hsa-miR-3680	CLIP-seq
MIRT2174486	hsa-miR-382	CLIP-seq
MIRT2478016	hsa-miR-3908	CLIP-seq
MIRT2478017	hsa-miR-3929	CLIP-seq
MIRT2174487	hsa-miR-3973	CLIP-seq
MIRT2478018	hsa-miR-4419b	CLIP-seq
MIRT2478019	hsa-miR-4422	CLIP-seq
MIRT1934744	hsa-miR-4429	CLIP-seq
MIRT2478020	hsa-miR-4478	CLIP-seq
MIRT2478021	hsa-miR-4495	CLIP-seq
MIRT2174497	hsa-miR-4646-3p	CLIP-seq
MIRT2478022	hsa-miR-4662a-5p	CLIP-seq
MIRT2174498	hsa-miR-4678	CLIP-seq
MIRT2478023	hsa-miR-4690-5p	CLIP-seq
MIRT794973	hsa-miR-4691-3p	CLIP-seq
MIRT2174500	hsa-miR-4697-3p	CLIP-seq
MIRT2174502	hsa-miR-4729	CLIP-seq
MIRT795010	hsa-miR-4773	CLIP-seq
MIRT2174504	hsa-miR-4777-5p	CLIP-seq
MIRT1545510	hsa-miR-494	CLIP-seq
MIRT794985	hsa-miR-495	CLIP-seq
MIRT794989	hsa-miR-500a	CLIP-seq
MIRT2174508	hsa-miR-500b	CLIP-seq
MIRT794990	hsa-miR-501-5p	CLIP-seq
MIRT2174509	hsa-miR-507	CLIP-seq
MIRT2174517	hsa-miR-548l	CLIP-seq
MIRT794995	hsa-miR-549	CLIP-seq
MIRT2174521	hsa-miR-557	CLIP-seq
MIRT1934750	hsa-miR-579	CLIP-seq
MIRT2478024	hsa-miR-921	CLIP-seq
MIRT2478012	hsa-miR-188-5p	CLIP-seq
MIRT2174474	hsa-miR-223	CLIP-seq
MIRT2174475	hsa-miR-2355-3p	CLIP-seq
MIRT2478013	hsa-miR-3121-3p	CLIP-seq
MIRT2174478	hsa-miR-3121-5p	CLIP-seq
MIRT1934733	hsa-miR-3140-3p	CLIP-seq
MIRT794940	hsa-miR-3157-5p	CLIP-seq
MIRT2478014	hsa-miR-3189-3p	CLIP-seq
MIRT2478015	hsa-miR-3606	CLIP-seq
MIRT2174482	hsa-miR-362-5p	CLIP-seq
MIRT2174485	hsa-miR-3671	CLIP-seq
MIRT1934742	hsa-miR-3680	CLIP-seq
MIRT2174486	hsa-miR-382	CLIP-seq
MIRT2478016	hsa-miR-3908	CLIP-seq
MIRT2478017	hsa-miR-3929	CLIP-seq
MIRT2174487	hsa-miR-3973	CLIP-seq
MIRT2478018	hsa-miR-4419b	CLIP-seq
MIRT2478019	hsa-miR-4422	CLIP-seq
MIRT2478020	hsa-miR-4478	CLIP-seq
MIRT2478021	hsa-miR-4495	CLIP-seq
MIRT2174497	hsa-miR-4646-3p	CLIP-seq
MIRT2478022	hsa-miR-4662a-5p	CLIP-seq
MIRT2478023	hsa-miR-4690-5p	CLIP-seq
MIRT794973	hsa-miR-4691-3p	CLIP-seq
MIRT2174500	hsa-miR-4697-3p	CLIP-seq
MIRT2174502	hsa-miR-4729	CLIP-seq
MIRT2174504	hsa-miR-4777-5p	CLIP-seq
MIRT1545510	hsa-miR-494	CLIP-seq
MIRT794985	hsa-miR-495	CLIP-seq
MIRT2174508	hsa-miR-500b	CLIP-seq
MIRT794990	hsa-miR-501-5p	CLIP-seq
MIRT2174509	hsa-miR-507	CLIP-seq
MIRT2174517	hsa-miR-548l	CLIP-seq
MIRT794995	hsa-miR-549	CLIP-seq
MIRT2174521	hsa-miR-557	CLIP-seq
MIRT1934750	hsa-miR-579	CLIP-seq
MIRT2478024	hsa-miR-921	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002053	Process	Positive regulation of mesenchymal cell proliferation	IEA
GO:0003924	Function	GTPase activity	TAS	8537347
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	TAS	8537347
GO:0005515	Function	Protein binding	IPI	23622247, 32203420
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	8537347
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IEA
GO:0007155	Process	Cell adhesion	TAS	8537347
GO:0007165	Process	Signal transduction	IEA
GO:0007266	Process	Rho protein signal transduction	IBA
GO:0007266	Process	Rho protein signal transduction	TAS	8537347
GO:0008361	Process	Regulation of cell size	IBA
GO:0008361	Process	Regulation of cell size	IEA
GO:0010631	Process	Epithelial cell migration	IEA
GO:0010634	Process	Positive regulation of epithelial cell migration	IEA
GO:0016020	Component	Membrane	IEA
GO:0016477	Process	Cell migration	IEA
GO:0030879	Process	Mammary gland development	IEA
GO:0030879	Process	Mammary gland development	IEA
GO:0042169	Function	SH2 domain binding	IPI	1689011
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS

Other IDs

• MIM: 602680
• HGNC: 675
• e!Ensembl: ENSG00000100852

Protein

• UniProt ID: Q13017
• Protein name: Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)
• Protein function: GTPase-activating protein for Rho family members (PubMed:8537347).
• PDB: 2EE4, 2EE5, 5U4V
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00071	Ras	142 → 248	Ras family	Domain
  PF16512	RhoGAP-FF1	260 → 338	p190-A and -B Rho GAPs FF domain	Domain
  PF01846	FF	485 → 545	FF domain	Family
  PF00620	RhoGAP	1275 → 1426	RhoGAP domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in skin fibroblasts (at protein level) (PubMed:8537347). {ECO:0000269|PubMed:8537347}.
• Sequence:

  MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTI
  DFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAA
  ASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFV
  NNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFT
  ALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNH
  PDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLN
  WSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQH
  LISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQR
  EIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRES
  LLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFI
  LGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFC
  VFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQ
  LANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRI
  VMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSI
  GVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKEL
  MTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQ
  SEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYP
  IHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLA
  HPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDR
  TSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPL
  LSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYF
  GMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINL
  VSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPV
  NYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVET
  FIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLG
  II

• Sequence length: 1502

Pathways

KEGG:

Focal adhesion
Leukocyte transendothelial migration

Reactome:

Rho GTPase cycle

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Martsolf syndrome 1	Likely pathogenic	rs2550691751	RCV002305659	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Pulmonary artery atresia	Pathogenic	rs200111638	RCV002512186	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ARHGAP5-related disorder	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL ATRESIA OF PULMONARY ARTERY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
STOMACH NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Carcinoma	Breast Carcinoma	BEFREE	10939588		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Carcinoma	Breast Carcinoma	GWASCAT_DG	29059683		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	34370213, 36077054	Associate	★☆☆☆☆ Found in Text Mining only
Capillary Leak Syndrome	Capillary leak syndrome	Pubtator	29097442	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	36354136	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	23474761		★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	36632741	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37845228	Inhibit	★☆☆☆☆ Found in Text Mining only
Critical Illness	Critical illness	Pubtator	29097442	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	24316134	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	18996642		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	23474761		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	23474761	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	10939588		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	23474761		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	30250020, 31097692		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	23474761, 30250020		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	23474761		★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	Pubtator	35757478	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	30250020, 31097692		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	31097692	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	34285193, 35894701, 36595859	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	36632741	Associate	★☆☆☆☆ Found in Text Mining only