Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	391013
Gene name	Phospholipase A2 group IIC
Gene symbol	PLA2G2C
Synonyms (NCBI Gene)	UBXN10-AS1
Chromosome	1
Chromosome location	1p36.12

136

Show/Hide all (136)

miRTarBase ID	miRNA	Experiments	Reference
MIRT709046	hsa-miR-873-5p	HITS-CLIP	19536157
MIRT709045	hsa-miR-1910-5p	HITS-CLIP	19536157
MIRT709044	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT709043	hsa-miR-4793-5p	HITS-CLIP	19536157
MIRT709042	hsa-miR-6072	HITS-CLIP	19536157
MIRT709041	hsa-miR-6891-3p	HITS-CLIP	19536157
MIRT709040	hsa-miR-3664-3p	HITS-CLIP	19536157
MIRT709039	hsa-miR-6870-3p	HITS-CLIP	19536157
MIRT709038	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT690781	hsa-miR-4282	HITS-CLIP	23313552
MIRT690780	hsa-miR-3664-5p	HITS-CLIP	23313552
MIRT690779	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT690778	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT690777	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT690776	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT690775	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT690774	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT690773	hsa-miR-3120-5p	HITS-CLIP	23313552
MIRT690772	hsa-miR-4522	HITS-CLIP	23313552
MIRT690771	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT690770	hsa-miR-6888-3p	HITS-CLIP	23313552
MIRT690769	hsa-miR-3672	HITS-CLIP	23313552
MIRT690768	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT690767	hsa-miR-6510-3p	HITS-CLIP	23313552
MIRT508629	hsa-miR-6732-3p	PAR-CLIP	23446348
MIRT508628	hsa-miR-10a-5p	PAR-CLIP	23446348
MIRT508627	hsa-miR-10b-5p	PAR-CLIP	23446348
MIRT515072	hsa-miR-28-3p	PAR-CLIP	23446348
MIRT515071	hsa-miR-5680	PAR-CLIP	23446348
MIRT508626	hsa-miR-1272	PAR-CLIP	23446348
MIRT508625	hsa-miR-338-3p	PAR-CLIP	23446348
MIRT508624	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT508623	hsa-miR-339-5p	PAR-CLIP	23446348
MIRT508622	hsa-miR-4421	PAR-CLIP	23446348
MIRT508621	hsa-miR-5699-3p	PAR-CLIP	23446348
MIRT515070	hsa-miR-6508-5p	PAR-CLIP	23446348
MIRT515069	hsa-miR-8067	PAR-CLIP	23446348
MIRT508620	hsa-miR-3190-5p	PAR-CLIP	23446348
MIRT515068	hsa-miR-6895-3p	PAR-CLIP	23446348
MIRT515067	hsa-miR-593-3p	PAR-CLIP	23446348
MIRT515066	hsa-miR-4684-5p	PAR-CLIP	23446348
MIRT508619	hsa-miR-4435	PAR-CLIP	23446348
MIRT515065	hsa-miR-6818-3p	PAR-CLIP	23446348
MIRT508629	hsa-miR-6732-3p	PAR-CLIP	23446348
MIRT508628	hsa-miR-10a-5p	PAR-CLIP	23446348
MIRT508627	hsa-miR-10b-5p	PAR-CLIP	23446348
MIRT508626	hsa-miR-1272	PAR-CLIP	23446348
MIRT508625	hsa-miR-338-3p	PAR-CLIP	23446348
MIRT508624	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT508623	hsa-miR-339-5p	PAR-CLIP	23446348
MIRT508622	hsa-miR-4421	PAR-CLIP	23446348
MIRT508621	hsa-miR-5699-3p	PAR-CLIP	23446348
MIRT508620	hsa-miR-3190-5p	PAR-CLIP	23446348
MIRT508619	hsa-miR-4435	PAR-CLIP	23446348
MIRT453145	hsa-miR-1296-3p	PAR-CLIP	23592263
MIRT453144	hsa-miR-194-3p	PAR-CLIP	23592263
MIRT453143	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT453142	hsa-miR-6835-5p	PAR-CLIP	23592263
MIRT453141	hsa-miR-6752-5p	PAR-CLIP	23592263
MIRT453140	hsa-miR-6842-5p	PAR-CLIP	23592263
MIRT453139	hsa-miR-7110-5p	PAR-CLIP	23592263
MIRT453138	hsa-miR-4447	PAR-CLIP	23592263
MIRT453137	hsa-miR-4472	PAR-CLIP	23592263
MIRT453136	hsa-miR-4709-3p	PAR-CLIP	23592263
MIRT453135	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT453134	hsa-miR-6751-5p	PAR-CLIP	23592263
MIRT453133	hsa-miR-6803-5p	PAR-CLIP	23592263
MIRT453132	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT709046	hsa-miR-873-5p	HITS-CLIP	19536157
MIRT709045	hsa-miR-1910-5p	HITS-CLIP	19536157
MIRT709044	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT709043	hsa-miR-4793-5p	HITS-CLIP	19536157
MIRT709042	hsa-miR-6072	HITS-CLIP	19536157
MIRT709041	hsa-miR-6891-3p	HITS-CLIP	19536157
MIRT709040	hsa-miR-3664-3p	HITS-CLIP	19536157
MIRT709039	hsa-miR-6870-3p	HITS-CLIP	19536157
MIRT709038	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT690781	hsa-miR-4282	HITS-CLIP	23313552
MIRT690780	hsa-miR-3664-5p	HITS-CLIP	23313552
MIRT690779	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT690778	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT690777	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT690776	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT690775	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT690774	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT690773	hsa-miR-3120-5p	HITS-CLIP	23313552
MIRT690772	hsa-miR-4522	HITS-CLIP	23313552
MIRT690771	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT690770	hsa-miR-6888-3p	HITS-CLIP	23313552
MIRT690769	hsa-miR-3672	HITS-CLIP	23313552
MIRT690768	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT690767	hsa-miR-6510-3p	HITS-CLIP	23313552
MIRT508629	hsa-miR-6732-3p	PAR-CLIP	23446348
MIRT508628	hsa-miR-10a-5p	PAR-CLIP	23446348
MIRT508627	hsa-miR-10b-5p	PAR-CLIP	23446348
MIRT515072	hsa-miR-28-3p	PAR-CLIP	23446348
MIRT515071	hsa-miR-5680	PAR-CLIP	23446348
MIRT508626	hsa-miR-1272	PAR-CLIP	23446348
MIRT508625	hsa-miR-338-3p	PAR-CLIP	23446348
MIRT508624	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT508623	hsa-miR-339-5p	PAR-CLIP	23446348
MIRT508622	hsa-miR-4421	PAR-CLIP	23446348
MIRT508621	hsa-miR-5699-3p	PAR-CLIP	23446348
MIRT515070	hsa-miR-6508-5p	PAR-CLIP	23446348
MIRT515069	hsa-miR-8067	PAR-CLIP	23446348
MIRT508620	hsa-miR-3190-5p	PAR-CLIP	23446348
MIRT515068	hsa-miR-6895-3p	PAR-CLIP	23446348
MIRT515067	hsa-miR-593-3p	PAR-CLIP	23446348
MIRT515066	hsa-miR-4684-5p	PAR-CLIP	23446348
MIRT508619	hsa-miR-4435	PAR-CLIP	23446348
MIRT515065	hsa-miR-6818-3p	PAR-CLIP	23446348
MIRT508629	hsa-miR-6732-3p	PAR-CLIP	23446348
MIRT508628	hsa-miR-10a-5p	PAR-CLIP	23446348
MIRT508627	hsa-miR-10b-5p	PAR-CLIP	23446348
MIRT508626	hsa-miR-1272	PAR-CLIP	23446348
MIRT508625	hsa-miR-338-3p	PAR-CLIP	23446348
MIRT508624	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT508623	hsa-miR-339-5p	PAR-CLIP	23446348
MIRT508622	hsa-miR-4421	PAR-CLIP	23446348
MIRT508621	hsa-miR-5699-3p	PAR-CLIP	23446348
MIRT508620	hsa-miR-3190-5p	PAR-CLIP	23446348
MIRT508619	hsa-miR-4435	PAR-CLIP	23446348
MIRT453145	hsa-miR-1296-3p	PAR-CLIP	23592263
MIRT453144	hsa-miR-194-3p	PAR-CLIP	23592263
MIRT453143	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT453142	hsa-miR-6835-5p	PAR-CLIP	23592263
MIRT453141	hsa-miR-6752-5p	PAR-CLIP	23592263
MIRT453140	hsa-miR-6842-5p	PAR-CLIP	23592263
MIRT453139	hsa-miR-7110-5p	PAR-CLIP	23592263
MIRT453138	hsa-miR-4447	PAR-CLIP	23592263
MIRT453137	hsa-miR-4472	PAR-CLIP	23592263
MIRT453136	hsa-miR-4709-3p	PAR-CLIP	23592263
MIRT453135	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT453134	hsa-miR-6751-5p	PAR-CLIP	23592263
MIRT453133	hsa-miR-6803-5p	PAR-CLIP	23592263
MIRT453132	hsa-miR-6516-5p	PAR-CLIP	23592263

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence
GO:0005102	Function	Signaling receptor binding	IBA
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005543	Function	Phospholipid binding	IBA
GO:0005576	Component	Extracellular region	IEA
GO:0006644	Process	Phospholipid metabolic process	IEA
GO:0016042	Process	Lipid catabolic process	IEA
GO:0046470	Process	Phosphatidylcholine metabolic process	IBA
GO:0046470	Process	Phosphatidylcholine metabolic process	IEA
GO:0046471	Process	Phosphatidylglycerol metabolic process	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0047498	Function	Calcium-dependent phospholipase A2 activity	IBA
GO:0050482	Process	Arachidonate secretion	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q5R387

Protein name

Putative inactive group IIC secretory phospholipase A2 (Phosphatidylcholine 2-acylhydrolase-like protein GIIC)

Protein function

Inactive phospholipase.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00068	Phospholip_A2_1	20 → 134	Phospholipase A2	Domain

Sequence

MKVIAILTLLLFCSPTHSSFWQFQRRVKHITGRSAFFSYYGYGCYCGLGDKGIPVDDTDR
HSPSSPSPYEKLKEFSCQPVLNSYQFHIVNGAVVCGCTLGPGASCHCRLKACECDKQSVH
CFKESLPTYEKNFKQFSSQPRCGRHKPWC

Sequence length

149

Interactions

View interactions

	KEGG
	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways Ras signaling pathway Vascular smooth muscle contraction Pancreatic secretion Fat digestion and absorption

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenomatous Polyps	Adenomatous Polyposis	BEFREE	8640784		★★★★★ ★☆☆☆☆ Found in Text Mining only

PLA2G2C (phospholipase A2 group IIC)