ANXA2R (annexin A2 receptor)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID 389289
Gene name Annexin A2 receptor
Gene symbol ANXA2R
Synonyms (NCBI Gene)
AX2RAXIIRC5orf39
Chromosome 5
Chromosome location 5p12
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all (2)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 30833792
GO:0038023 Function Signaling receptor activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
611296 33463 ENSG00000177721
Protein Protein information from UniProt database.
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q3ZCQ2
Protein name Annexin-2 receptor (Annexin II receptor) (AXIIR)
Protein function May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15721 ANXA2R 2 → 193 Annexin-2 receptor Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Highly expressed in lymphocytes. Expressed in both resting CD4(+) and CD8(+) T-cells. {ECO:0000269|PubMed:16895901}.
Sequence
Sequence length 193
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Gene Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
URINARY BLADDER NEOPLASMS — CTD
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (7)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Bladder Neoplasm Bladder Neoplasm CTD_human_DG 26039340
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma Renal Cell Renal cell carcinoma Pubtator 37464398 Stimulate
★★★★★
★☆☆☆☆
Found in Text Mining only
Liver carcinoma Liver carcinoma BEFREE 29422116
★★★★★
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of urinary bladder Urinary bladder cancer CTD_human_DG 26039340
★★★★★
★☆☆☆☆
Found in Text Mining only
Multiple Myeloma Multiple myeloma BEFREE 22223826
★★★★★
★☆☆☆☆
Found in Text Mining only
Prostatic Neoplasms Prostatic Neoplasms LHGDN 18636554
★★★★★
★☆☆☆☆
Found in Text Mining only
Uveal melanoma Uveal Melanoma BEFREE 27183438, 31462126
★★★★★
★☆☆☆☆
Found in Text Mining only