Gene Gene information from NCBI Gene database.
Entrez ID 388403
Gene name Yippee like 2
Gene symbol YPEL2
Synonyms (NCBI Gene)
FKSG4
Chromosome 17
Chromosome location 17q22
miRNA miRNA information provided by mirtarbase database.
658
miRTarBase ID miRNA Experiments Reference
MIRT018689 hsa-miR-335-5p Microarray 18185580
MIRT044530 hsa-miR-320a CLASH 23622248
MIRT463768 hsa-miR-548aa PAR-CLIP 23592263
MIRT463767 hsa-miR-548ap-3p PAR-CLIP 23592263
MIRT463766 hsa-miR-548t-3p PAR-CLIP 23592263
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IEA
GO:0005730 Component Nucleolus IEA
GO:0046872 Function Metal ion binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609723 18326 ENSG00000175155
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96QA6
Protein name Protein yippee-like 2
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03226 Yippee-Mis18 19 118 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Detected in fetal and adult kidney, heart, liver, lung and skeletal muscle. {ECO:0000269|PubMed:15556292}.
Sequence
Sequence length 119
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
9
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ASTROCYTOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BREAST CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Breast Carcinoma Breast Carcinoma BEFREE 19454617
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Breast Neoplasms Breast neoplasm Pubtator 19454617, 34990474 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma Renal Cell Renal cell carcinoma Pubtator 35674183 Associate
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of breast Breast Cancer BEFREE 19454617
★☆☆☆☆
Found in Text Mining only