KLK2 (kallikrein related peptidase 2)

Gene

• Entrez ID: 3817
• Gene name: Kallikrein related peptidase 2
• Gene symbol: KLK2
• Synonyms (NCBI Gene): KLK2A2, hGK-1, hK2
• Chromosome: 19
• Chromosome location: 19q13.33
• Summary: This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT722828	hsa-miR-21-5p	HITS-CLIP	19536157
MIRT722827	hsa-miR-590-5p	HITS-CLIP	19536157
MIRT722826	hsa-miR-1245a	HITS-CLIP	19536157
MIRT722825	hsa-miR-8079	HITS-CLIP	19536157
MIRT722824	hsa-miR-5190	HITS-CLIP	19536157
MIRT722823	hsa-miR-4267	HITS-CLIP	19536157
MIRT722822	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT722821	hsa-miR-4276	HITS-CLIP	19536157
MIRT722820	hsa-miR-7108-5p	HITS-CLIP	19536157
MIRT722819	hsa-miR-4474-3p	HITS-CLIP	19536157
MIRT646547	hsa-miR-4779	HITS-CLIP	23824327
MIRT646545	hsa-miR-4661-3p	HITS-CLIP	23824327
MIRT646544	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT646543	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT646542	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT646541	hsa-miR-1248	HITS-CLIP	23824327
MIRT646540	hsa-miR-767-3p	HITS-CLIP	23824327
MIRT646539	hsa-miR-6894-5p	HITS-CLIP	23824327
MIRT646538	hsa-miR-4266	HITS-CLIP	23824327
MIRT646537	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT646535	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT646536	hsa-miR-6071	HITS-CLIP	23824327
MIRT646534	hsa-miR-1178-3p	HITS-CLIP	23824327
MIRT646533	hsa-miR-544a	HITS-CLIP	23824327
MIRT646532	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT722828	hsa-miR-21-5p	HITS-CLIP	19536157
MIRT722827	hsa-miR-590-5p	HITS-CLIP	19536157
MIRT722826	hsa-miR-1245a	HITS-CLIP	19536157
MIRT722825	hsa-miR-8079	HITS-CLIP	19536157
MIRT722824	hsa-miR-5190	HITS-CLIP	19536157
MIRT722823	hsa-miR-4267	HITS-CLIP	19536157
MIRT722822	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT722821	hsa-miR-4276	HITS-CLIP	19536157
MIRT722820	hsa-miR-7108-5p	HITS-CLIP	19536157
MIRT722819	hsa-miR-4474-3p	HITS-CLIP	19536157
MIRT646547	hsa-miR-4779	HITS-CLIP	23824327
MIRT646545	hsa-miR-4661-3p	HITS-CLIP	23824327
MIRT646544	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT646543	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT646542	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT646541	hsa-miR-1248	HITS-CLIP	23824327
MIRT646540	hsa-miR-767-3p	HITS-CLIP	23824327
MIRT646539	hsa-miR-6894-5p	HITS-CLIP	23824327
MIRT646538	hsa-miR-4266	HITS-CLIP	23824327
MIRT646537	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT646535	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT646536	hsa-miR-6071	HITS-CLIP	23824327
MIRT646534	hsa-miR-1178-3p	HITS-CLIP	23824327
MIRT646533	hsa-miR-544a	HITS-CLIP	23824327
MIRT646532	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT610804	hsa-miR-5193	HITS-CLIP	23824327
MIRT610803	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610802	hsa-miR-370-3p	HITS-CLIP	23824327
MIRT610801	hsa-miR-6893-3p	HITS-CLIP	23824327
MIRT610800	hsa-miR-1976	HITS-CLIP	23824327
MIRT610799	hsa-miR-326	HITS-CLIP	23824327
MIRT610798	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT610797	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT610796	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT610794	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT610795	hsa-miR-612	HITS-CLIP	23824327
MIRT610792	hsa-miR-6860	HITS-CLIP	23824327
MIRT610793	hsa-miR-4486	HITS-CLIP	23824327
MIRT610791	hsa-miR-378g	HITS-CLIP	23824327
MIRT610790	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT610789	hsa-miR-3650	HITS-CLIP	23824327
MIRT610788	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT610787	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT610786	hsa-miR-5691	HITS-CLIP	23824327
MIRT610785	hsa-miR-6805-3p	HITS-CLIP	23824327
MIRT1099028	hsa-miR-1264	CLIP-seq
MIRT1099029	hsa-miR-147	CLIP-seq
MIRT1099030	hsa-miR-199a-5p	CLIP-seq
MIRT1099031	hsa-miR-199b-5p	CLIP-seq
MIRT1099032	hsa-miR-3657	CLIP-seq
MIRT1099033	hsa-miR-3909	CLIP-seq
MIRT1099034	hsa-miR-3919	CLIP-seq
MIRT1099035	hsa-miR-3942-3p	CLIP-seq
MIRT1099036	hsa-miR-4255	CLIP-seq
MIRT1099037	hsa-miR-4307	CLIP-seq
MIRT1099038	hsa-miR-4417	CLIP-seq
MIRT1099039	hsa-miR-4420	CLIP-seq
MIRT1099040	hsa-miR-4642	CLIP-seq
MIRT1099041	hsa-miR-4669	CLIP-seq
MIRT1099042	hsa-miR-4676-5p	CLIP-seq
MIRT1099043	hsa-miR-4756-3p	CLIP-seq
MIRT1099044	hsa-miR-494	CLIP-seq
MIRT1099045	hsa-miR-544	CLIP-seq
MIRT1099046	hsa-miR-575	CLIP-seq
MIRT1099047	hsa-miR-599	CLIP-seq
MIRT1099028	hsa-miR-1264	CLIP-seq
MIRT1099030	hsa-miR-199a-5p	CLIP-seq
MIRT1099031	hsa-miR-199b-5p	CLIP-seq
MIRT1099034	hsa-miR-3919	CLIP-seq
MIRT1099036	hsa-miR-4255	CLIP-seq
MIRT2026886	hsa-miR-4469	CLIP-seq
MIRT1099042	hsa-miR-4676-5p	CLIP-seq
MIRT1099043	hsa-miR-4756-3p	CLIP-seq
MIRT1099046	hsa-miR-575	CLIP-seq
MIRT2026887	hsa-miR-624	CLIP-seq
MIRT1099028	hsa-miR-1264	CLIP-seq
MIRT1099030	hsa-miR-199a-5p	CLIP-seq
MIRT1099031	hsa-miR-199b-5p	CLIP-seq
MIRT2258146	hsa-miR-3674	CLIP-seq
MIRT1099034	hsa-miR-3919	CLIP-seq
MIRT1099036	hsa-miR-4255	CLIP-seq
MIRT2258147	hsa-miR-4320	CLIP-seq
MIRT2258148	hsa-miR-4328	CLIP-seq
MIRT2258149	hsa-miR-4659a-3p	CLIP-seq
MIRT2258150	hsa-miR-4659b-3p	CLIP-seq
MIRT1099042	hsa-miR-4676-5p	CLIP-seq
MIRT2258151	hsa-miR-4713-5p	CLIP-seq
MIRT1099043	hsa-miR-4756-3p	CLIP-seq
MIRT2258152	hsa-miR-4778-3p	CLIP-seq
MIRT2258153	hsa-miR-4793-3p	CLIP-seq
MIRT2258154	hsa-miR-516a-3p	CLIP-seq
MIRT1099046	hsa-miR-575	CLIP-seq
MIRT2465543	hsa-miR-1915	CLIP-seq
MIRT2465544	hsa-miR-2355-5p	CLIP-seq
MIRT2465545	hsa-miR-605	CLIP-seq
MIRT1099028	hsa-miR-1264	CLIP-seq
MIRT1099030	hsa-miR-199a-5p	CLIP-seq
MIRT1099031	hsa-miR-199b-5p	CLIP-seq
MIRT1099034	hsa-miR-3919	CLIP-seq
MIRT1099036	hsa-miR-4255	CLIP-seq
MIRT1099042	hsa-miR-4676-5p	CLIP-seq
MIRT1099043	hsa-miR-4756-3p	CLIP-seq
MIRT1099046	hsa-miR-575	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
AR	Unknown	11532861;16751804;20688158;9241247

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003073	Process	Regulation of systemic arterial blood pressure	IBA
GO:0004252	Function	Serine-type endopeptidase activity	IBA
GO:0004252	Function	Serine-type endopeptidase activity	IDA	9042371
GO:0004252	Function	Serine-type endopeptidase activity	IEA
GO:0004252	Function	Serine-type endopeptidase activity	TAS	10463585
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IBA
GO:0006508	Process	Proteolysis	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008236	Function	Serine-type peptidase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0030141	Component	Secretory granule	IBA
GO:0031638	Process	Zymogen activation	IBA
GO:0070062	Component	Extracellular exosome	HDA	23533145

Other IDs

• MIM: 147960
• HGNC: 6363
• e!Ensembl: ENSG00000167751

Protein

• UniProt ID: P20151
• Protein name: Kallikrein-2 (EC 3.4.21.35) (Glandular kallikrein-1) (hGK-1) (Tissue kallikrein-2)
• Protein function: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
• PDB: 4NFE, 4NFF
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00089	Trypsin	25 → 253	Trypsin	Domain

• Sequence:

  MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
  LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
  LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
  NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP
  AVYTKVVHYRKWIKDTIAANP

• Sequence length: 261

Pathways

KEGG:

Renin-angiotensin system
Endocrine and other factor-regulated calcium reabsorption

Reactome:

Activation of Matrix Metalloproteinases
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CELIAC DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESTROGEN-RECEPTOR NEGATIVE BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN ENDOMETRIOID CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN SEROUS CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	BEFREE	1370633		★☆☆☆☆ Found in Text Mining only
Benign Prostatic Hyperplasia	Benign Prostatic Hyperplasia	BEFREE	24711254		★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	31574376		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	12124798, 12633763, 27058005, 30254080		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	27058005	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	27823965		★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	31574376		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	19170196		★☆☆☆☆ Found in Text Mining only
Chromophobe Renal Cell Carcinoma	Chromophobe Carcinoma	BEFREE	29707153		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	18772588		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	10614994		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	23911596		★☆☆☆☆ Found in Text Mining only
Head and Neck Carcinoma	Head And Neck Carcinoma	BEFREE	31105886		★☆☆☆☆ Found in Text Mining only
Hyperlipidemia Familial Combined	Hyperlipidemia	Pubtator	23877856	Associate	★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	30875800		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	19170196	Stimulate	★☆☆☆☆ Found in Text Mining only
Malignant Head and Neck Neoplasm	Head and neck cancer	BEFREE	31105886		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	12124798, 12633763, 27058005, 30254080		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	19170196		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	10197620, 10325497, 11901813, 11948967, 12142383, 12466122, 12805332, 15474988, 15643194, 16172196, 16322300, 17085659, 17257635, 17593395, 18451133, 19050691, 19233911, 20424135, 20460480, 21178268, 21372204, 23359319, 25153383, 25153393, 25354797, 25847286, 28802831, 29691406, 30260630, 30334974, 31043681, 31391553, 9804390		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	CTD_human_DG	15643194, 17085659		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	31574376		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	12633763, 14672622, 20424135		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	18772588		★☆☆☆☆ Found in Text Mining only
Malignant tumor of small intestine	Small intestine cancer	BEFREE	28802831		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	LHGDN	12124798		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	11948967, 14672622, 25847286, 30307468, 9815828, 9865729		★☆☆☆☆ Found in Text Mining only
PACHYONYCHIA CONGENITA 3	Pachyonychia Congenita	BEFREE	12767274		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	30267647		★☆☆☆☆ Found in Text Mining only
Prostate cancer, familial	Prostate cancer	BEFREE	27819754		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	10197620, 10325497, 11294823, 11753974, 11901813, 11948967, 12142383, 12466122, 12805332, 15474988, 15643194, 16172196, 16322300, 17085659, 17257635, 17593395, 18451133, 19050691, 19233911, 20424135, 20460480, 21178268, 21372204, 23359319, 25153383, 25354797, 25847286, 28802831, 29691406, 30260630, 30334974, 31043681, 31391553, 9804390		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	11486050, 11834722, 19318432, 20424135, 20460480, 21178268, 21372204, 25847286, 25969144, 28802831, 30307468, 30334974, 33596994, 34254325	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic Neoplasms	CTD_human_DG	15643194, 17085659		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	16388506, 17085659, 17257635, 17593395, 18567807, 19003994		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	10614994		★☆☆☆☆ Found in Text Mining only
Small intestine carcinoma	Small Intestinal Carcinoma	BEFREE	28802831		★☆☆☆☆ Found in Text Mining only