Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	3775
Gene name	Potassium two pore domain channel subfamily K member 1
Gene symbol	KCNK1
Synonyms (NCBI Gene)	DPKHOHOK2P1K2p1.1KCNO1TWIK-1TWIK1
Chromosome	1
Chromosome location	1q42.2
Summary	This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins fo

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019653	hsa-miR-340-5p	Sequencing	20371350
MIRT022480	hsa-miR-124-3p	Microarray	18668037
MIRT028202	hsa-miR-33a-5p	Sequencing	20371350
MIRT710232	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT710231	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710230	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT710229	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT710228	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT710227	hsa-miR-6716-5p	HITS-CLIP	19536157
MIRT710226	hsa-miR-4666a-5p	HITS-CLIP	19536157
MIRT710225	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT710224	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT720216	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT720215	hsa-miR-342-3p	HITS-CLIP	19536157
MIRT720214	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT720213	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT710232	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT710231	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710230	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT710229	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT710228	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT710227	hsa-miR-6716-5p	HITS-CLIP	19536157
MIRT710226	hsa-miR-4666a-5p	HITS-CLIP	19536157
MIRT710225	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT710224	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT720216	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT720215	hsa-miR-342-3p	HITS-CLIP	19536157
MIRT720214	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT720213	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT710232	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT710231	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710230	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT710229	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT710228	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT710227	hsa-miR-6716-5p	HITS-CLIP	19536157
MIRT710226	hsa-miR-4666a-5p	HITS-CLIP	19536157
MIRT710225	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT710224	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT509258	hsa-miR-8485	HITS-CLIP	21572407
MIRT509260	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT509259	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT509257	hsa-miR-603	HITS-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT509255	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT509252	hsa-miR-4759	HITS-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707311	hsa-miR-6074	HITS-CLIP	21572407
MIRT509254	hsa-miR-3941	HITS-CLIP	21572407
MIRT509251	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT499301	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509253	hsa-miR-3924	HITS-CLIP	21572407
MIRT499299	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	HITS-CLIP	23706177
MIRT509251	hsa-miR-4789-5p	HITS-CLIP	23706177
MIRT499301	hsa-miR-190a-3p	HITS-CLIP	23706177
MIRT499299	hsa-miR-1277-5p	HITS-CLIP	23706177
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT509258	hsa-miR-8485	PAR-CLIP	21572407
MIRT509260	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT509259	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT509257	hsa-miR-603	PAR-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT509254	hsa-miR-3941	PAR-CLIP	21572407
MIRT509253	hsa-miR-3924	PAR-CLIP	21572407
MIRT509258	hsa-miR-8485	PAR-CLIP	21572407
MIRT509257	hsa-miR-603	PAR-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT509252	hsa-miR-4759	PAR-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509254	hsa-miR-3941	PAR-CLIP	21572407
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509258	hsa-miR-8485	PAR-CLIP	21572407
MIRT509260	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT509259	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT509257	hsa-miR-603	PAR-CLIP	21572407
MIRT509254	hsa-miR-3941	PAR-CLIP	21572407
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT509255	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509253	hsa-miR-3924	PAR-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509258	hsa-miR-8485	PAR-CLIP	23446348
MIRT509260	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT509259	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT509257	hsa-miR-603	PAR-CLIP	23446348
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT509252	hsa-miR-4759	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509254	hsa-miR-3941	PAR-CLIP	23446348
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509253	hsa-miR-3924	PAR-CLIP	23446348
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509260	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT509259	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT509258	hsa-miR-8485	PAR-CLIP	23446348
MIRT509257	hsa-miR-603	PAR-CLIP	23446348
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT509255	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT509254	hsa-miR-3941	PAR-CLIP	23446348
MIRT509253	hsa-miR-3924	PAR-CLIP	23446348
MIRT509252	hsa-miR-4759	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	24398324
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	24398324
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	24398324
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	27292025
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	27292025
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	27292025
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	27292025
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	27292025
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	27292025
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	27292025
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	27292025
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	27292025
MIRT710232	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT710231	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710230	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT710229	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT710228	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT710227	hsa-miR-6716-5p	HITS-CLIP	19536157
MIRT710226	hsa-miR-4666a-5p	HITS-CLIP	19536157
MIRT710225	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT710224	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT720216	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT720215	hsa-miR-342-3p	HITS-CLIP	19536157
MIRT720214	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT720213	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT710232	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT710231	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710230	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT710229	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT710228	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT710227	hsa-miR-6716-5p	HITS-CLIP	19536157
MIRT710226	hsa-miR-4666a-5p	HITS-CLIP	19536157
MIRT710225	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT710224	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT720216	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT720215	hsa-miR-342-3p	HITS-CLIP	19536157
MIRT720214	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT720213	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT710232	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT710231	hsa-miR-6852-5p	HITS-CLIP	19536157
MIRT710230	hsa-miR-6742-3p	HITS-CLIP	19536157
MIRT710229	hsa-miR-204-3p	HITS-CLIP	19536157
MIRT710228	hsa-miR-4646-5p	HITS-CLIP	19536157
MIRT710227	hsa-miR-6716-5p	HITS-CLIP	19536157
MIRT710226	hsa-miR-4666a-5p	HITS-CLIP	19536157
MIRT710225	hsa-miR-1343-3p	HITS-CLIP	19536157
MIRT710224	hsa-miR-6783-3p	HITS-CLIP	19536157
MIRT509258	hsa-miR-8485	HITS-CLIP	21572407
MIRT509260	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT509259	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT509257	hsa-miR-603	HITS-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT509255	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT509252	hsa-miR-4759	HITS-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707311	hsa-miR-6074	HITS-CLIP	21572407
MIRT509254	hsa-miR-3941	HITS-CLIP	21572407
MIRT509251	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT499301	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT509253	hsa-miR-3924	HITS-CLIP	21572407
MIRT499299	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	HITS-CLIP	23706177
MIRT509251	hsa-miR-4789-5p	HITS-CLIP	23706177
MIRT499301	hsa-miR-190a-3p	HITS-CLIP	23706177
MIRT499299	hsa-miR-1277-5p	HITS-CLIP	23706177
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT509258	hsa-miR-8485	PAR-CLIP	21572407
MIRT509260	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT509259	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT509257	hsa-miR-603	PAR-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT509254	hsa-miR-3941	PAR-CLIP	21572407
MIRT509253	hsa-miR-3924	PAR-CLIP	21572407
MIRT509258	hsa-miR-8485	PAR-CLIP	21572407
MIRT509257	hsa-miR-603	PAR-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT509252	hsa-miR-4759	PAR-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT509254	hsa-miR-3941	PAR-CLIP	21572407
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509258	hsa-miR-8485	PAR-CLIP	21572407
MIRT509260	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT509259	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT509257	hsa-miR-603	PAR-CLIP	21572407
MIRT509254	hsa-miR-3941	PAR-CLIP	21572407
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT509255	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT509253	hsa-miR-3924	PAR-CLIP	21572407
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509258	hsa-miR-8485	PAR-CLIP	23446348
MIRT509260	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT509259	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT509257	hsa-miR-603	PAR-CLIP	23446348
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT509252	hsa-miR-4759	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509254	hsa-miR-3941	PAR-CLIP	23446348
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509253	hsa-miR-3924	PAR-CLIP	23446348
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509260	hsa-miR-329-3p	PAR-CLIP	23446348
MIRT509259	hsa-miR-362-3p	PAR-CLIP	23446348
MIRT509258	hsa-miR-8485	PAR-CLIP	23446348
MIRT509257	hsa-miR-603	PAR-CLIP	23446348
MIRT509256	hsa-miR-4789-3p	PAR-CLIP	23446348
MIRT509255	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT509254	hsa-miR-3941	PAR-CLIP	23446348
MIRT509253	hsa-miR-3924	PAR-CLIP	23446348
MIRT509252	hsa-miR-4759	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509251	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT499300	hsa-miR-5011-5p	PAR-CLIP	24398324
MIRT499301	hsa-miR-190a-3p	PAR-CLIP	24398324
MIRT499299	hsa-miR-1277-5p	PAR-CLIP	24398324
MIRT1081733	hsa-miR-103a	CLIP-seq
MIRT1081734	hsa-miR-106a	CLIP-seq
MIRT1081735	hsa-miR-106b	CLIP-seq
MIRT1081736	hsa-miR-107	CLIP-seq
MIRT1081737	hsa-miR-1225-5p	CLIP-seq
MIRT1081738	hsa-miR-1262	CLIP-seq
MIRT1081739	hsa-miR-1293	CLIP-seq
MIRT1081740	hsa-miR-1297	CLIP-seq
MIRT1081741	hsa-miR-1301	CLIP-seq
MIRT1081742	hsa-miR-140-3p	CLIP-seq
MIRT1081743	hsa-miR-145	CLIP-seq
MIRT1081744	hsa-miR-15a	CLIP-seq
MIRT1081745	hsa-miR-15b	CLIP-seq
MIRT1081746	hsa-miR-16	CLIP-seq
MIRT1081747	hsa-miR-17	CLIP-seq
MIRT1081748	hsa-miR-195	CLIP-seq
MIRT1081749	hsa-miR-20a	CLIP-seq
MIRT1081750	hsa-miR-20b	CLIP-seq
MIRT1081751	hsa-miR-25	CLIP-seq
MIRT1081752	hsa-miR-26a	CLIP-seq
MIRT1081753	hsa-miR-26b	CLIP-seq
MIRT1081754	hsa-miR-3163	CLIP-seq
MIRT1081755	hsa-miR-3180-5p	CLIP-seq
MIRT1081756	hsa-miR-32	CLIP-seq
MIRT1081757	hsa-miR-3609	CLIP-seq
MIRT1081758	hsa-miR-3617	CLIP-seq
MIRT1081759	hsa-miR-363	CLIP-seq
MIRT1081760	hsa-miR-367	CLIP-seq
MIRT1081761	hsa-miR-3977	CLIP-seq
MIRT1081762	hsa-miR-424	CLIP-seq
MIRT1081763	hsa-miR-4279	CLIP-seq
MIRT1081764	hsa-miR-4465	CLIP-seq
MIRT1081765	hsa-miR-4483	CLIP-seq
MIRT1081766	hsa-miR-4643	CLIP-seq
MIRT1081767	hsa-miR-466	CLIP-seq
MIRT1081768	hsa-miR-4668-3p	CLIP-seq
MIRT1081769	hsa-miR-4686	CLIP-seq
MIRT1081770	hsa-miR-4701-3p	CLIP-seq
MIRT1081771	hsa-miR-4712-5p	CLIP-seq
MIRT1081772	hsa-miR-4775	CLIP-seq
MIRT1081773	hsa-miR-4790-5p	CLIP-seq
MIRT1081774	hsa-miR-4796-3p	CLIP-seq
MIRT1081775	hsa-miR-497	CLIP-seq
MIRT1081776	hsa-miR-5047	CLIP-seq
MIRT1081777	hsa-miR-518a-5p	CLIP-seq
MIRT1081778	hsa-miR-519d	CLIP-seq
MIRT1081779	hsa-miR-527	CLIP-seq
MIRT1081780	hsa-miR-548ah	CLIP-seq
MIRT1081781	hsa-miR-561	CLIP-seq
MIRT1081782	hsa-miR-584	CLIP-seq
MIRT1081783	hsa-miR-590-3p	CLIP-seq
MIRT1081784	hsa-miR-630	CLIP-seq
MIRT1081785	hsa-miR-641	CLIP-seq
MIRT1081786	hsa-miR-770-5p	CLIP-seq
MIRT1081787	hsa-miR-922	CLIP-seq
MIRT1081788	hsa-miR-92a	CLIP-seq
MIRT1081789	hsa-miR-92b	CLIP-seq
MIRT1081790	hsa-miR-93	CLIP-seq
MIRT1081733	hsa-miR-103a	CLIP-seq
MIRT1081734	hsa-miR-106a	CLIP-seq
MIRT1081735	hsa-miR-106b	CLIP-seq
MIRT1081736	hsa-miR-107	CLIP-seq
MIRT1081741	hsa-miR-1301	CLIP-seq
MIRT2020245	hsa-miR-137	CLIP-seq
MIRT1081747	hsa-miR-17	CLIP-seq
MIRT1081749	hsa-miR-20a	CLIP-seq
MIRT1081750	hsa-miR-20b	CLIP-seq
MIRT1081751	hsa-miR-25	CLIP-seq
MIRT2020246	hsa-miR-3132	CLIP-seq
MIRT2020247	hsa-miR-3138	CLIP-seq
MIRT2020248	hsa-miR-3140-3p	CLIP-seq
MIRT1081756	hsa-miR-32	CLIP-seq
MIRT2020249	hsa-miR-340	CLIP-seq
MIRT1081757	hsa-miR-3609	CLIP-seq
MIRT1081759	hsa-miR-363	CLIP-seq
MIRT1081760	hsa-miR-367	CLIP-seq
MIRT2020250	hsa-miR-3974	CLIP-seq
MIRT1081761	hsa-miR-3977	CLIP-seq
MIRT2020251	hsa-miR-4639-3p	CLIP-seq
MIRT2020252	hsa-miR-4650-3p	CLIP-seq
MIRT2020253	hsa-miR-4729	CLIP-seq
MIRT1081772	hsa-miR-4775	CLIP-seq
MIRT1081773	hsa-miR-4790-5p	CLIP-seq
MIRT1081774	hsa-miR-4796-3p	CLIP-seq
MIRT2020254	hsa-miR-494	CLIP-seq
MIRT1081776	hsa-miR-5047	CLIP-seq
MIRT2020255	hsa-miR-513c	CLIP-seq
MIRT2020256	hsa-miR-514b-5p	CLIP-seq
MIRT1081778	hsa-miR-519d	CLIP-seq
MIRT1081780	hsa-miR-548ah	CLIP-seq
MIRT1081782	hsa-miR-584	CLIP-seq
MIRT1081783	hsa-miR-590-3p	CLIP-seq
MIRT1081787	hsa-miR-922	CLIP-seq
MIRT1081788	hsa-miR-92a	CLIP-seq
MIRT1081789	hsa-miR-92b	CLIP-seq
MIRT1081790	hsa-miR-93	CLIP-seq
MIRT1081733	hsa-miR-103a	CLIP-seq
MIRT1081734	hsa-miR-106a	CLIP-seq
MIRT1081735	hsa-miR-106b	CLIP-seq
MIRT1081736	hsa-miR-107	CLIP-seq
MIRT2252074	hsa-miR-1238	CLIP-seq
MIRT1081740	hsa-miR-1297	CLIP-seq
MIRT1081741	hsa-miR-1301	CLIP-seq
MIRT2020245	hsa-miR-137	CLIP-seq
MIRT1081742	hsa-miR-140-3p	CLIP-seq
MIRT1081744	hsa-miR-15a	CLIP-seq
MIRT1081745	hsa-miR-15b	CLIP-seq
MIRT1081746	hsa-miR-16	CLIP-seq
MIRT1081747	hsa-miR-17	CLIP-seq
MIRT1081748	hsa-miR-195	CLIP-seq
MIRT1081749	hsa-miR-20a	CLIP-seq
MIRT1081750	hsa-miR-20b	CLIP-seq
MIRT1081751	hsa-miR-25	CLIP-seq
MIRT1081752	hsa-miR-26a	CLIP-seq
MIRT1081753	hsa-miR-26b	CLIP-seq
MIRT2020246	hsa-miR-3132	CLIP-seq
MIRT2020247	hsa-miR-3138	CLIP-seq
MIRT2020248	hsa-miR-3140-3p	CLIP-seq
MIRT1081754	hsa-miR-3163	CLIP-seq
MIRT1081756	hsa-miR-32	CLIP-seq
MIRT2252075	hsa-miR-33a	CLIP-seq
MIRT2252076	hsa-miR-33b	CLIP-seq
MIRT1081757	hsa-miR-3609	CLIP-seq
MIRT1081759	hsa-miR-363	CLIP-seq
MIRT1081760	hsa-miR-367	CLIP-seq
MIRT2252077	hsa-miR-370	CLIP-seq
MIRT2252078	hsa-miR-375	CLIP-seq
MIRT2252079	hsa-miR-380	CLIP-seq
MIRT2020250	hsa-miR-3974	CLIP-seq
MIRT1081761	hsa-miR-3977	CLIP-seq
MIRT1081762	hsa-miR-424	CLIP-seq
MIRT1081763	hsa-miR-4279	CLIP-seq
MIRT2252080	hsa-miR-4315	CLIP-seq
MIRT1081764	hsa-miR-4465	CLIP-seq
MIRT2252081	hsa-miR-4495	CLIP-seq
MIRT2252082	hsa-miR-450b-5p	CLIP-seq
MIRT2020252	hsa-miR-4650-3p	CLIP-seq
MIRT1081768	hsa-miR-4668-3p	CLIP-seq
MIRT1081769	hsa-miR-4686	CLIP-seq
MIRT2020253	hsa-miR-4729	CLIP-seq
MIRT2252083	hsa-miR-4731-5p	CLIP-seq
MIRT2252084	hsa-miR-4762-3p	CLIP-seq
MIRT1081772	hsa-miR-4775	CLIP-seq
MIRT1081773	hsa-miR-4790-5p	CLIP-seq
MIRT2252085	hsa-miR-4793-5p	CLIP-seq
MIRT1081774	hsa-miR-4796-3p	CLIP-seq
MIRT2020254	hsa-miR-494	CLIP-seq
MIRT1081775	hsa-miR-497	CLIP-seq
MIRT1081776	hsa-miR-5047	CLIP-seq
MIRT2252086	hsa-miR-507	CLIP-seq
MIRT2252087	hsa-miR-511	CLIP-seq
MIRT1081778	hsa-miR-519d	CLIP-seq
MIRT1081780	hsa-miR-548ah	CLIP-seq
MIRT2252088	hsa-miR-548c-3p	CLIP-seq
MIRT2252089	hsa-miR-557	CLIP-seq
MIRT1081782	hsa-miR-584	CLIP-seq
MIRT1081783	hsa-miR-590-3p	CLIP-seq
MIRT2252090	hsa-miR-615-5p	CLIP-seq
MIRT1081784	hsa-miR-630	CLIP-seq
MIRT1081787	hsa-miR-922	CLIP-seq
MIRT1081788	hsa-miR-92a	CLIP-seq
MIRT1081789	hsa-miR-92b	CLIP-seq
MIRT1081790	hsa-miR-93	CLIP-seq

Show/Hide all (54)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005242	Function	Inward rectifier potassium channel activity	TAS	8605869
GO:0005249	Function	Voltage-gated potassium channel activity	IDA	21653227
GO:0005267	Function	Potassium channel activity	IDA	22282804
GO:0005267	Function	Potassium channel activity	IEA
GO:0005272	Function	Sodium channel activity	IDA	21653227
GO:0005272	Function	Sodium channel activity	IEA
GO:0005515	Function	Protein binding	IPI	20498050, 23169818, 32296183
GO:0005768	Component	Endosome	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	21653227, 23169818
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006813	Process	Potassium ion transport	IEA
GO:0006813	Process	Potassium ion transport	TAS	8605869
GO:0008076	Component	Voltage-gated potassium channel complex	TAS	8605869
GO:0014047	Process	Glutamate secretion	IEA
GO:0014047	Process	Glutamate secretion	ISS
GO:0016020	Component	Membrane	IDA	22282804
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IEA
GO:0022834	Function	Ligand-gated channel activity	IEA
GO:0022834	Function	Ligand-gated channel activity	ISS
GO:0022841	Function	Potassium ion leak channel activity	IBA
GO:0022841	Function	Potassium ion leak channel activity	IDA	21653227
GO:0022841	Function	Potassium ion leak channel activity	IEA
GO:0030425	Component	Dendrite	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031526	Component	Brush border membrane	IEA
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034705	Component	Potassium channel complex	IDA	22282804
GO:0035094	Process	Response to nicotine	IEA
GO:0035725	Process	Sodium ion transmembrane transport	IDA	21653227
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	20498050, 22282804
GO:0042995	Component	Cell projection	IEA
GO:0043204	Component	Perikaryon	IEA
GO:0045202	Component	Synapse	IEA
GO:0046982	Function	Protein heterodimerization activity	IDA	23169818
GO:0046982	Function	Protein heterodimerization activity	IEA
GO:0046982	Function	Protein heterodimerization activity	ISS
GO:0055037	Component	Recycling endosome	IEA
GO:0060075	Process	Regulation of resting membrane potential	IMP	21653227
GO:0060078	Process	Regulation of postsynaptic membrane potential	IEA
GO:0071468	Process	Cellular response to acidic pH	IEA
GO:0071805	Process	Potassium ion transmembrane transport	IBA
GO:0071805	Process	Potassium ion transmembrane transport	IDA	21653227, 22282804
GO:0071805	Process	Potassium ion transmembrane transport	IEA
GO:0097060	Component	Synaptic membrane	IEA
GO:1902476	Process	Chloride transmembrane transport	IEA
GO:1902476	Process	Chloride transmembrane transport	ISS
GO:1902937	Component	Inward rectifier potassium channel complex	IEA
GO:1905030	Function	Voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IEA

MIM	HGNC	e!Ensembl
601745	6272	ENSG00000135750

O00180

Protein name

Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel K2P1) (Potassium channel KCNO1)

Protein function

Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues (PubMed:15820677, PubMed:21653227). Forms dimeric chan

PDB

3UKM

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07885	Ion_trans_2	82 → 158	Ion channel	Family
PF07885	Ion_trans_2	190 → 271	Ion channel	Family

Tissue specificity

TISSUE SPECIFICITY: Detected in bronchial epithelial cells (PubMed:21964404). Detected in heart left atrium and left ventricle (PubMed:17478540). Detected in cardiac myocytes (at protein level) (PubMed:21653227). Widely expressed with high levels in heart

Sequence

MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK
RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGY
GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVA
IVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK
FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLS
FSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH

Sequence length

336

Interactions

View interactions

	Reactome
			Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) Phase 4 - resting membrane potential

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (9)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETIC RETINOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERPLASIA	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBSTRUCTIVE SLEEP APNEA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PERIODONTITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SINUSITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TREATMENT-RESISTANT HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (17)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	29050937		★★★★★ ★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Atrial fibrillation	Pubtator	15942582	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Atrial Fibrillation	BEFREE	16027256, 27103460		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	31362134		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brugada Syndrome (disorder)	Brugada Syndrome	BEFREE	19029124		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	26503814		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	GWASCAT_DG	26503814		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Periodontitis	Periodontitis	BEFREE	25056994		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Periodontitis	Periodontitis	Pubtator	25056994	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	18239687		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	18239687	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart valve disease	Cardiac valvular disease	BEFREE	16027256		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	GWASCAT_DG	26718567		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	31362134		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	18239687	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	18239687	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	Pubtator	25056994	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

KCNK1 (potassium two pore domain channel subfamily K member 1)