IVD (isovaleryl-CoA dehydrogenase)

Gene

• Entrez ID: 3712
• Gene name: Isovaleryl-CoA dehydrogenase
• Gene symbol: IVD
• Synonyms (NCBI Gene): ACAD2, IVDH
• Chromosome: 15
• Chromosome location: 15q15.1
• Summary: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs2229311	G>A,C,T	Pathogenic-likely-pathogenic	Missense variant, non coding transcript variant, coding sequence variant, intron variant
rs28940889	C>T	Pathogenic	Non coding transcript variant, missense variant, genic downstream transcript variant, coding sequence variant
rs34695403	C>G,T	Uncertain-significance, likely-pathogenic	Non coding transcript variant, intron variant, missense variant, coding sequence variant
rs121434284	T>C	Pathogenic	Coding sequence variant, upstream transcript variant, missense variant, genic upstream transcript variant, non coding transcript variant, 5 prime UTR variant
rs121434285	G>T	Uncertain-significance, pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs140098686	C>T	Conflicting-interpretations-of-pathogenicity	Non coding transcript variant, intron variant, synonymous variant, coding sequence variant
rs142761835	G>A	Pathogenic-likely-pathogenic, pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs143348838	G>A	Likely-pathogenic, uncertain-significance	Coding sequence variant, missense variant, non coding transcript variant, genic downstream transcript variant, intron variant
rs145999491	A>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Non coding transcript variant, intron variant, missense variant, coding sequence variant
rs146861563	C>T	Likely-pathogenic, uncertain-significance	Missense variant, non coding transcript variant, coding sequence variant
rs367814475	G>C,T	Pathogenic	Coding sequence variant, genic downstream transcript variant, non coding transcript variant, missense variant
rs368705240	C>T	Pathogenic	Intron variant, downstream transcript variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant, stop gained
rs371427844	C>T	Pathogenic	Missense variant, intron variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant
rs373534546	G>A,T	Conflicting-interpretations-of-pathogenicity	Missense variant, downstream transcript variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant
rs373594717	A>C,G,T	Likely-pathogenic	Upstream transcript variant, genic upstream transcript variant, missense variant, initiator codon variant, non coding transcript variant, 5 prime UTR variant
rs377147994	G>A	Pathogenic	Splice donor variant
rs398123679	G>A	Conflicting-interpretations-of-pathogenicity, likely-pathogenic	Missense variant, intron variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant
rs398123680	T>C	Likely-pathogenic	Missense variant, intron variant, downstream transcript variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant
rs398123681	C>G,T	Uncertain-significance, pathogenic-likely-pathogenic	Missense variant, intron variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant, stop gained
rs398123682	TG>-	Likely-pathogenic, pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant
rs398123683	T>C	Pathogenic	Splice donor variant
rs398123684	G>-	Pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant
rs540375168	G>A	Pathogenic	Stop gained, coding sequence variant, non coding transcript variant
rs566691073	T>C,G	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, 5 prime UTR variant, upstream transcript variant, initiator codon variant, non coding transcript variant, missense variant
rs745629936	G>A	Likely-pathogenic	Downstream transcript variant, splice donor variant, genic downstream transcript variant
rs757261752	A>C,T	Likely-pathogenic	Initiator codon variant, missense variant, 5 prime UTR variant, upstream transcript variant, non coding transcript variant, genic upstream transcript variant, coding sequence variant
rs759159766	->G	Pathogenic	Downstream transcript variant, coding sequence variant, frameshift variant, non coding transcript variant, genic downstream transcript variant
rs763422682	T>C	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, intron variant, non coding transcript variant, genic downstream transcript variant
rs763471771	G>A	Pathogenic	Splice donor variant
rs765815516	C>T	Pathogenic	Intron variant, non coding transcript variant, stop gained, coding sequence variant
rs769048174	T>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs771914739	A>C,G	Likely-pathogenic	Splice acceptor variant
rs773560012	A>G	Pathogenic-likely-pathogenic	Intron variant, coding sequence variant, non coding transcript variant, genic downstream transcript variant, missense variant
rs776015412	C>T	Likely-pathogenic	Stop gained, coding sequence variant, non coding transcript variant
rs776608445	C>G,T	Pathogenic, uncertain-significance	Intron variant, coding sequence variant, non coding transcript variant, genic downstream transcript variant, missense variant
rs781630355	T>-	Pathogenic, conflicting-interpretations-of-pathogenicity	Frameshift variant, coding sequence variant, non coding transcript variant
rs786204427	CA>GG	Likely-pathogenic	Intron variant, splice acceptor variant
rs786204613	T>-	Pathogenic-likely-pathogenic, likely-pathogenic	Intron variant, coding sequence variant, non coding transcript variant, frameshift variant, genic downstream transcript variant
rs796051982	->GTG	Likely-pathogenic	Inframe insertion, coding sequence variant, non coding transcript variant
rs796051983	C>T	Likely-pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant
rs907414760	G>A,C	Likely-pathogenic	5 prime UTR variant, genic upstream transcript variant, non coding transcript variant, missense variant, upstream transcript variant, coding sequence variant, stop gained
rs928991928	G>A,C	Likely-pathogenic	5 prime UTR variant, upstream transcript variant, splice donor variant, non coding transcript variant, genic upstream transcript variant
rs982218848	G>A	Pathogenic	Genic downstream transcript variant, intron variant, non coding transcript variant, missense variant, coding sequence variant
rs1057516769	->T	Likely-pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs1057517043	G>A	Likely-pathogenic	Splice acceptor variant
rs1057517056	A>G	Likely-pathogenic	Intron variant, genic downstream transcript variant, splice acceptor variant
rs1057517379	CG>-	Likely-pathogenic	Frameshift variant, genic upstream transcript variant, 5 prime UTR variant, upstream transcript variant, non coding transcript variant, coding sequence variant
rs1057524715	T>A	Likely-pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs1237032588	C>T	Pathogenic	Missense variant, intron variant, coding sequence variant, genic downstream transcript variant, non coding transcript variant
rs1364046355	C>-	Pathogenic	Frameshift variant, coding sequence variant, non coding transcript variant
rs1398838997	G>A	Likely-pathogenic	Splice acceptor variant
rs1477527791	G>A	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, missense variant, non coding transcript variant, intron variant
rs1555403211	->ATGG	Likely-pathogenic	Coding sequence variant, intron variant, non coding transcript variant, frameshift variant
rs1555403942	ACACGCTAATCTCACAGTGCAACCACCAACTAAAAGATACCCTCTCCCCTTGGGGGCCAGTCAGACCTGCTTTCTGTAGCATGCTGCCATGAACCAAATGTGGTTAGGAAGGGGCCATGGATTGCTTTAAAATACTTGAGCCAAAAATAATAAAAATAGGACCAGAACTCTTGCATTGAACAACAGACAGACAACATTTGAAGAGAACTCTAAGAAATGGAAGAGTAGGACTAGCTTCCTTTGCAAAGGGAATGG	Likely-pathogenic	Splice acceptor variant, coding sequence variant, non coding transcript variant, intron variant
rs1555404010	G>A	Likely-pathogenic	Missense variant, coding sequence variant, non coding transcript variant
rs1555404426	->T	Likely-pathogenic	Stop gained, coding sequence variant, non coding transcript variant
rs1555404784	G>A	Likely-pathogenic	Splice acceptor variant, 3 prime UTR variant, non coding transcript variant
rs1555405067	G>T	Likely-pathogenic	Splice acceptor variant, intron variant, genic downstream transcript variant
rs1555405070	A>-	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant, non coding transcript variant, intron variant
rs1555405080	C>-	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant, non coding transcript variant, intron variant
rs1555405428	GGCGGCTGGTCATCGGCAGAGCCTTCAA>-	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, frameshift variant, non coding transcript variant, intron variant
rs1566936542	C>-	Likely-pathogenic	Non coding transcript variant, coding sequence variant, frameshift variant
rs1595786853	A>T	Likely-pathogenic	Non coding transcript variant, downstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant
rs1595797766	A>-	Pathogenic	Non coding transcript variant, intron variant, coding sequence variant, frameshift variant, genic downstream transcript variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022872	hsa-miR-124-3p	Microarray	18668037
MIRT052426	hsa-let-7a-5p	CLASH	23622248
MIRT051477	hsa-let-7e-5p	CLASH	23622248
MIRT041643	hsa-miR-484	CLASH	23622248
MIRT041124	hsa-miR-503-5p	CLASH	23622248
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT677717	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677716	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT677715	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT675667	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT675666	hsa-miR-6131	HITS-CLIP	23824327
MIRT637949	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT637953	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637949	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT519194	hsa-miR-4438	PAR-CLIP	23446348
MIRT519193	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT519192	hsa-miR-6760-3p	PAR-CLIP	23446348
MIRT519191	hsa-miR-1208	PAR-CLIP	23446348
MIRT519190	hsa-miR-6889-3p	PAR-CLIP	23446348
MIRT519189	hsa-miR-5702	PAR-CLIP	23446348
MIRT519188	hsa-miR-4425	PAR-CLIP	23446348
MIRT519187	hsa-miR-3147	PAR-CLIP	23446348
MIRT519186	hsa-miR-5095	PAR-CLIP	23446348
MIRT519185	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT519184	hsa-miR-937-5p	PAR-CLIP	23446348
MIRT519183	hsa-miR-450b-3p	PAR-CLIP	23446348
MIRT519182	hsa-miR-769-3p	PAR-CLIP	23446348
MIRT519181	hsa-miR-6728-5p	PAR-CLIP	23446348
MIRT519179	hsa-miR-5089-5p	PAR-CLIP	23446348
MIRT519180	hsa-miR-6513-5p	PAR-CLIP	23446348
MIRT519178	hsa-miR-619-5p	PAR-CLIP	23446348
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT677717	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677716	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT677715	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT675668	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT675667	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT675666	hsa-miR-6131	HITS-CLIP	23824327
MIRT637949	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT637956	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT637955	hsa-miR-764	HITS-CLIP	23824327
MIRT637954	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT637953	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT637951	hsa-miR-4635	HITS-CLIP	23824327
MIRT637952	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT637950	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT637948	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT637949	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT637947	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT637946	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT637945	hsa-miR-640	HITS-CLIP	23824327
MIRT519194	hsa-miR-4438	PAR-CLIP	23446348
MIRT519193	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT519192	hsa-miR-6760-3p	PAR-CLIP	23446348
MIRT519191	hsa-miR-1208	PAR-CLIP	23446348
MIRT519190	hsa-miR-6889-3p	PAR-CLIP	23446348
MIRT519189	hsa-miR-5702	PAR-CLIP	23446348
MIRT519188	hsa-miR-4425	PAR-CLIP	23446348
MIRT519187	hsa-miR-3147	PAR-CLIP	23446348
MIRT519186	hsa-miR-5095	PAR-CLIP	23446348
MIRT519185	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT519184	hsa-miR-937-5p	PAR-CLIP	23446348
MIRT519183	hsa-miR-450b-3p	PAR-CLIP	23446348
MIRT519182	hsa-miR-769-3p	PAR-CLIP	23446348
MIRT519181	hsa-miR-6728-5p	PAR-CLIP	23446348
MIRT519179	hsa-miR-5089-5p	PAR-CLIP	23446348
MIRT519180	hsa-miR-6513-5p	PAR-CLIP	23446348
MIRT519178	hsa-miR-619-5p	PAR-CLIP	23446348
MIRT1075516	hsa-miR-1200	CLIP-seq
MIRT1075517	hsa-miR-122	CLIP-seq
MIRT1075518	hsa-miR-1225-3p	CLIP-seq
MIRT1075519	hsa-miR-1228	CLIP-seq
MIRT1075520	hsa-miR-1233	CLIP-seq
MIRT1075521	hsa-miR-1279	CLIP-seq
MIRT1075522	hsa-miR-1286	CLIP-seq
MIRT1075523	hsa-miR-1288	CLIP-seq
MIRT1075524	hsa-miR-1291	CLIP-seq
MIRT1075525	hsa-miR-129-5p	CLIP-seq
MIRT1075526	hsa-miR-130a	CLIP-seq
MIRT1075527	hsa-miR-130b	CLIP-seq
MIRT1075528	hsa-miR-1539	CLIP-seq
MIRT1075529	hsa-miR-181a	CLIP-seq
MIRT1075530	hsa-miR-181b	CLIP-seq
MIRT1075531	hsa-miR-181c	CLIP-seq
MIRT1075532	hsa-miR-181d	CLIP-seq
MIRT1075533	hsa-miR-183	CLIP-seq
MIRT1075534	hsa-miR-184	CLIP-seq
MIRT1075535	hsa-miR-185	CLIP-seq
MIRT1075536	hsa-miR-1913	CLIP-seq
MIRT1075537	hsa-miR-197	CLIP-seq
MIRT1075538	hsa-miR-1976	CLIP-seq
MIRT1075539	hsa-miR-2392	CLIP-seq
MIRT1075540	hsa-miR-23a	CLIP-seq
MIRT1075541	hsa-miR-23b	CLIP-seq
MIRT1075542	hsa-miR-23c	CLIP-seq
MIRT1075543	hsa-miR-24	CLIP-seq
MIRT1075544	hsa-miR-301a	CLIP-seq
MIRT1075545	hsa-miR-301b	CLIP-seq
MIRT1075546	hsa-miR-3135b	CLIP-seq
MIRT1075547	hsa-miR-3152-5p	CLIP-seq
MIRT1075548	hsa-miR-3155	CLIP-seq
MIRT1075549	hsa-miR-3155b	CLIP-seq
MIRT1075550	hsa-miR-3157-3p	CLIP-seq
MIRT1075551	hsa-miR-3159	CLIP-seq
MIRT1075552	hsa-miR-3162-5p	CLIP-seq
MIRT1075553	hsa-miR-3182	CLIP-seq
MIRT1075554	hsa-miR-3184	CLIP-seq
MIRT1075555	hsa-miR-3193	CLIP-seq
MIRT1075556	hsa-miR-3199	CLIP-seq
MIRT1075557	hsa-miR-3200-3p	CLIP-seq
MIRT1075558	hsa-miR-320a	CLIP-seq
MIRT1075559	hsa-miR-320b	CLIP-seq
MIRT1075560	hsa-miR-320c	CLIP-seq
MIRT1075561	hsa-miR-320d	CLIP-seq
MIRT1075562	hsa-miR-320e	CLIP-seq
MIRT1075563	hsa-miR-324-3p	CLIP-seq
MIRT1075564	hsa-miR-328	CLIP-seq
MIRT1075565	hsa-miR-329	CLIP-seq
MIRT1075566	hsa-miR-3545-3p	CLIP-seq
MIRT1075567	hsa-miR-362-3p	CLIP-seq
MIRT1075568	hsa-miR-3652	CLIP-seq
MIRT1075569	hsa-miR-3655	CLIP-seq
MIRT1075570	hsa-miR-3664-3p	CLIP-seq
MIRT1075571	hsa-miR-3666	CLIP-seq
MIRT1075572	hsa-miR-3925-3p	CLIP-seq
MIRT1075573	hsa-miR-3944-5p	CLIP-seq
MIRT1075574	hsa-miR-423-5p	CLIP-seq
MIRT1075575	hsa-miR-4252	CLIP-seq
MIRT1075576	hsa-miR-4262	CLIP-seq
MIRT1075577	hsa-miR-4264	CLIP-seq
MIRT1075578	hsa-miR-4269	CLIP-seq
MIRT1075579	hsa-miR-4270	CLIP-seq
MIRT1075580	hsa-miR-4279	CLIP-seq
MIRT1075581	hsa-miR-4284	CLIP-seq
MIRT1075582	hsa-miR-4290	CLIP-seq
MIRT1075583	hsa-miR-4295	CLIP-seq
MIRT1075584	hsa-miR-4306	CLIP-seq
MIRT1075585	hsa-miR-4317	CLIP-seq
MIRT1075586	hsa-miR-4324	CLIP-seq
MIRT1075587	hsa-miR-4330	CLIP-seq
MIRT1075588	hsa-miR-4426	CLIP-seq
MIRT1075589	hsa-miR-4429	CLIP-seq
MIRT1075590	hsa-miR-4430	CLIP-seq
MIRT1075591	hsa-miR-4441	CLIP-seq
MIRT1075592	hsa-miR-4452	CLIP-seq
MIRT1075593	hsa-miR-4468	CLIP-seq
MIRT1075594	hsa-miR-4475	CLIP-seq
MIRT1075595	hsa-miR-4488	CLIP-seq
MIRT1075596	hsa-miR-451b	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT1075598	hsa-miR-454	CLIP-seq
MIRT1075599	hsa-miR-4644	CLIP-seq
MIRT1075600	hsa-miR-4647	CLIP-seq
MIRT1075601	hsa-miR-4659a-5p	CLIP-seq
MIRT1075602	hsa-miR-4659b-5p	CLIP-seq
MIRT1075603	hsa-miR-4662b	CLIP-seq
MIRT1075604	hsa-miR-4690-5p	CLIP-seq
MIRT1075605	hsa-miR-4691-3p	CLIP-seq
MIRT1075606	hsa-miR-4696	CLIP-seq
MIRT1075607	hsa-miR-4697-5p	CLIP-seq
MIRT1075608	hsa-miR-4698	CLIP-seq
MIRT1075609	hsa-miR-4700-3p	CLIP-seq
MIRT1075610	hsa-miR-4707-3p	CLIP-seq
MIRT1075611	hsa-miR-4715-3p	CLIP-seq
MIRT1075612	hsa-miR-4716-5p	CLIP-seq
MIRT1075613	hsa-miR-4722-3p	CLIP-seq
MIRT1075614	hsa-miR-4722-5p	CLIP-seq
MIRT1075615	hsa-miR-4735-5p	CLIP-seq
MIRT1075616	hsa-miR-4760-3p	CLIP-seq
MIRT1075617	hsa-miR-4763-5p	CLIP-seq
MIRT1075618	hsa-miR-4772-3p	CLIP-seq
MIRT1075619	hsa-miR-4774-3p	CLIP-seq
MIRT1075620	hsa-miR-4775	CLIP-seq
MIRT1075621	hsa-miR-4776-3p	CLIP-seq
MIRT1075622	hsa-miR-4781-3p	CLIP-seq
MIRT1075623	hsa-miR-4794	CLIP-seq
MIRT1075624	hsa-miR-486-5p	CLIP-seq
MIRT1075625	hsa-miR-488	CLIP-seq
MIRT1075626	hsa-miR-490-3p	CLIP-seq
MIRT1075627	hsa-miR-490-5p	CLIP-seq
MIRT1075628	hsa-miR-498	CLIP-seq
MIRT1075629	hsa-miR-5096	CLIP-seq
MIRT1075630	hsa-miR-515-5p	CLIP-seq
MIRT1075631	hsa-miR-544b	CLIP-seq
MIRT1075632	hsa-miR-556-5p	CLIP-seq
MIRT1075633	hsa-miR-582-3p	CLIP-seq
MIRT1075634	hsa-miR-590-3p	CLIP-seq
MIRT1075635	hsa-miR-596	CLIP-seq
MIRT1075636	hsa-miR-622	CLIP-seq
MIRT1075637	hsa-miR-649	CLIP-seq
MIRT1075638	hsa-miR-766	CLIP-seq
MIRT1075639	hsa-miR-874	CLIP-seq
MIRT1075640	hsa-miR-885-3p	CLIP-seq
MIRT1075641	hsa-miR-103a	CLIP-seq
MIRT1075642	hsa-miR-107	CLIP-seq
MIRT1075516	hsa-miR-1200	CLIP-seq
MIRT1075643	hsa-miR-1234	CLIP-seq
MIRT1075644	hsa-miR-1281	CLIP-seq
MIRT1075525	hsa-miR-129-5p	CLIP-seq
MIRT1075645	hsa-miR-1297	CLIP-seq
MIRT1075646	hsa-miR-1343	CLIP-seq
MIRT1075647	hsa-miR-15a	CLIP-seq
MIRT1075648	hsa-miR-15b	CLIP-seq
MIRT1075649	hsa-miR-16	CLIP-seq
MIRT1075536	hsa-miR-1913	CLIP-seq
MIRT1075650	hsa-miR-195	CLIP-seq
MIRT1075651	hsa-miR-2115	CLIP-seq
MIRT1075652	hsa-miR-214	CLIP-seq
MIRT1075653	hsa-miR-26a	CLIP-seq
MIRT1075654	hsa-miR-26b	CLIP-seq
MIRT1075655	hsa-miR-3074-5p	CLIP-seq
MIRT1075656	hsa-miR-3136-3p	CLIP-seq
MIRT1075548	hsa-miR-3155	CLIP-seq
MIRT1075549	hsa-miR-3155b	CLIP-seq
MIRT1075657	hsa-miR-3158-3p	CLIP-seq
MIRT1075658	hsa-miR-3187-3p	CLIP-seq
MIRT1075659	hsa-miR-3194-3p	CLIP-seq
MIRT1075558	hsa-miR-320a	CLIP-seq
MIRT1075559	hsa-miR-320b	CLIP-seq
MIRT1075560	hsa-miR-320c	CLIP-seq
MIRT1075561	hsa-miR-320d	CLIP-seq
MIRT1075562	hsa-miR-320e	CLIP-seq
MIRT1075563	hsa-miR-324-3p	CLIP-seq
MIRT1075566	hsa-miR-3545-3p	CLIP-seq
MIRT1075660	hsa-miR-3619-5p	CLIP-seq
MIRT1075661	hsa-miR-3691-3p	CLIP-seq
MIRT1075662	hsa-miR-370	CLIP-seq
MIRT1075663	hsa-miR-3909	CLIP-seq
MIRT1075573	hsa-miR-3944-5p	CLIP-seq
MIRT1075664	hsa-miR-424	CLIP-seq
MIRT1075575	hsa-miR-4252	CLIP-seq
MIRT1075581	hsa-miR-4284	CLIP-seq
MIRT1075665	hsa-miR-4291	CLIP-seq
MIRT1075666	hsa-miR-4313	CLIP-seq
MIRT1075667	hsa-miR-4320	CLIP-seq
MIRT1075586	hsa-miR-4324	CLIP-seq
MIRT1075587	hsa-miR-4330	CLIP-seq
MIRT1075589	hsa-miR-4429	CLIP-seq
MIRT1075668	hsa-miR-4435	CLIP-seq
MIRT1075669	hsa-miR-4465	CLIP-seq
MIRT1075593	hsa-miR-4468	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT1075601	hsa-miR-4659a-5p	CLIP-seq
MIRT1075602	hsa-miR-4659b-5p	CLIP-seq
MIRT1075670	hsa-miR-4663	CLIP-seq
MIRT1075605	hsa-miR-4691-3p	CLIP-seq
MIRT1075609	hsa-miR-4700-3p	CLIP-seq
MIRT1075671	hsa-miR-4701-5p	CLIP-seq
MIRT1075610	hsa-miR-4707-3p	CLIP-seq
MIRT1075672	hsa-miR-4731-3p	CLIP-seq
MIRT1075673	hsa-miR-4754	CLIP-seq
MIRT1075618	hsa-miR-4772-3p	CLIP-seq
MIRT1075621	hsa-miR-4776-3p	CLIP-seq
MIRT1075622	hsa-miR-4781-3p	CLIP-seq
MIRT1075674	hsa-miR-4782-5p	CLIP-seq
MIRT1075675	hsa-miR-4801	CLIP-seq
MIRT1075676	hsa-miR-497	CLIP-seq
MIRT1075628	hsa-miR-498	CLIP-seq
MIRT1075677	hsa-miR-512-5p	CLIP-seq
MIRT1075678	hsa-miR-516a-3p	CLIP-seq
MIRT1075631	hsa-miR-544b	CLIP-seq
MIRT1075679	hsa-miR-548s	CLIP-seq
MIRT1075680	hsa-miR-552	CLIP-seq
MIRT1075681	hsa-miR-588	CLIP-seq
MIRT1075682	hsa-miR-761	CLIP-seq
MIRT1075683	hsa-miR-767-3p	CLIP-seq
MIRT1075640	hsa-miR-885-3p	CLIP-seq
MIRT1075684	hsa-miR-891a	CLIP-seq
MIRT1075685	hsa-miR-922	CLIP-seq
MIRT2018766	hsa-miR-106a	CLIP-seq
MIRT2018767	hsa-miR-106b	CLIP-seq
MIRT1075516	hsa-miR-1200	CLIP-seq
MIRT2018768	hsa-miR-1207-3p	CLIP-seq
MIRT2018769	hsa-miR-1207-5p	CLIP-seq
MIRT1075517	hsa-miR-122	CLIP-seq
MIRT2018770	hsa-miR-1227	CLIP-seq
MIRT1075643	hsa-miR-1234	CLIP-seq
MIRT1075523	hsa-miR-1288	CLIP-seq
MIRT1075645	hsa-miR-1297	CLIP-seq
MIRT2018771	hsa-miR-150	CLIP-seq
MIRT2018772	hsa-miR-17	CLIP-seq
MIRT1075536	hsa-miR-1913	CLIP-seq
MIRT1075537	hsa-miR-197	CLIP-seq
MIRT1075538	hsa-miR-1976	CLIP-seq
MIRT2018773	hsa-miR-20a	CLIP-seq
MIRT2018774	hsa-miR-20b	CLIP-seq
MIRT1075651	hsa-miR-2115	CLIP-seq
MIRT2018775	hsa-miR-2355-5p	CLIP-seq
MIRT1075653	hsa-miR-26a	CLIP-seq
MIRT1075654	hsa-miR-26b	CLIP-seq
MIRT2018776	hsa-miR-302a	CLIP-seq
MIRT2018777	hsa-miR-302b	CLIP-seq
MIRT2018778	hsa-miR-302c	CLIP-seq
MIRT2018779	hsa-miR-302d	CLIP-seq
MIRT2018780	hsa-miR-302e	CLIP-seq
MIRT1075655	hsa-miR-3074-5p	CLIP-seq
MIRT2018781	hsa-miR-3126-3p	CLIP-seq
MIRT1075546	hsa-miR-3135b	CLIP-seq
MIRT2018782	hsa-miR-3149	CLIP-seq
MIRT1075556	hsa-miR-3199	CLIP-seq
MIRT1075562	hsa-miR-320e	CLIP-seq
MIRT1075563	hsa-miR-324-3p	CLIP-seq
MIRT2018783	hsa-miR-338-5p	CLIP-seq
MIRT1075566	hsa-miR-3545-3p	CLIP-seq
MIRT2018784	hsa-miR-3616-5p	CLIP-seq
MIRT2018785	hsa-miR-3647-5p	CLIP-seq
MIRT2018786	hsa-miR-3650	CLIP-seq
MIRT1075662	hsa-miR-370	CLIP-seq
MIRT2018787	hsa-miR-372	CLIP-seq
MIRT2018788	hsa-miR-373	CLIP-seq
MIRT2018789	hsa-miR-411	CLIP-seq
MIRT1075579	hsa-miR-4270	CLIP-seq
MIRT1075580	hsa-miR-4279	CLIP-seq
MIRT1075586	hsa-miR-4324	CLIP-seq
MIRT1075591	hsa-miR-4441	CLIP-seq
MIRT2018790	hsa-miR-4464	CLIP-seq
MIRT1075669	hsa-miR-4465	CLIP-seq
MIRT1075594	hsa-miR-4475	CLIP-seq
MIRT2018791	hsa-miR-4492	CLIP-seq
MIRT2018792	hsa-miR-4498	CLIP-seq
MIRT1075596	hsa-miR-451b	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT2018793	hsa-miR-4650-5p	CLIP-seq
MIRT1075670	hsa-miR-4663	CLIP-seq
MIRT1075604	hsa-miR-4690-5p	CLIP-seq
MIRT1075606	hsa-miR-4696	CLIP-seq
MIRT1075610	hsa-miR-4707-3p	CLIP-seq
MIRT2018794	hsa-miR-4713-5p	CLIP-seq
MIRT1075611	hsa-miR-4715-3p	CLIP-seq
MIRT1075613	hsa-miR-4722-3p	CLIP-seq
MIRT2018795	hsa-miR-4731-5p	CLIP-seq
MIRT2018796	hsa-miR-4733-3p	CLIP-seq
MIRT1075615	hsa-miR-4735-5p	CLIP-seq
MIRT2018797	hsa-miR-4748	CLIP-seq
MIRT2018798	hsa-miR-4763-3p	CLIP-seq
MIRT1075620	hsa-miR-4775	CLIP-seq
MIRT1075623	hsa-miR-4794	CLIP-seq
MIRT2018799	hsa-miR-4795-3p	CLIP-seq
MIRT2018800	hsa-miR-4795-5p	CLIP-seq
MIRT1075625	hsa-miR-488	CLIP-seq
MIRT1075629	hsa-miR-5096	CLIP-seq
MIRT2018801	hsa-miR-512-3p	CLIP-seq
MIRT2018802	hsa-miR-513b	CLIP-seq
MIRT1075678	hsa-miR-516a-3p	CLIP-seq
MIRT2018803	hsa-miR-519d	CLIP-seq
MIRT2018804	hsa-miR-520a-3p	CLIP-seq
MIRT2018805	hsa-miR-520b	CLIP-seq
MIRT2018806	hsa-miR-520c-3p	CLIP-seq
MIRT2018807	hsa-miR-520d-3p	CLIP-seq
MIRT2018808	hsa-miR-520e	CLIP-seq
MIRT2018809	hsa-miR-520g	CLIP-seq
MIRT2018810	hsa-miR-520h	CLIP-seq
MIRT1075631	hsa-miR-544b	CLIP-seq
MIRT1075679	hsa-miR-548s	CLIP-seq
MIRT2018811	hsa-miR-573	CLIP-seq
MIRT1075634	hsa-miR-590-3p	CLIP-seq
MIRT2018812	hsa-miR-645	CLIP-seq
MIRT2018813	hsa-miR-762	CLIP-seq
MIRT2018814	hsa-miR-93	CLIP-seq
MIRT2018768	hsa-miR-1207-3p	CLIP-seq
MIRT2250643	hsa-miR-2278	CLIP-seq
MIRT1075546	hsa-miR-3135b	CLIP-seq
MIRT2250644	hsa-miR-335	CLIP-seq
MIRT1075662	hsa-miR-370	CLIP-seq
MIRT2250645	hsa-miR-4421	CLIP-seq
MIRT1075608	hsa-miR-4698	CLIP-seq
MIRT1075678	hsa-miR-516a-3p	CLIP-seq
MIRT1075680	hsa-miR-552	CLIP-seq
MIRT2018766	hsa-miR-106a	CLIP-seq
MIRT2018767	hsa-miR-106b	CLIP-seq
MIRT2018768	hsa-miR-1207-3p	CLIP-seq
MIRT1075517	hsa-miR-122	CLIP-seq
MIRT1075643	hsa-miR-1234	CLIP-seq
MIRT2250646	hsa-miR-1243	CLIP-seq
MIRT2250647	hsa-miR-1245	CLIP-seq
MIRT2250648	hsa-miR-1255a	CLIP-seq
MIRT2250649	hsa-miR-1255b	CLIP-seq
MIRT2250650	hsa-miR-1267	CLIP-seq
MIRT1075644	hsa-miR-1281	CLIP-seq
MIRT2250651	hsa-miR-1293	CLIP-seq
MIRT1075525	hsa-miR-129-5p	CLIP-seq
MIRT2250652	hsa-miR-1296	CLIP-seq
MIRT1075645	hsa-miR-1297	CLIP-seq
MIRT2250653	hsa-miR-1304	CLIP-seq
MIRT1075526	hsa-miR-130a	CLIP-seq
MIRT1075527	hsa-miR-130b	CLIP-seq
MIRT1075646	hsa-miR-1343	CLIP-seq
MIRT2018771	hsa-miR-150	CLIP-seq
MIRT2018772	hsa-miR-17	CLIP-seq
MIRT1075536	hsa-miR-1913	CLIP-seq
MIRT1075537	hsa-miR-197	CLIP-seq
MIRT1075538	hsa-miR-1976	CLIP-seq
MIRT2018773	hsa-miR-20a	CLIP-seq
MIRT2018774	hsa-miR-20b	CLIP-seq
MIRT1075651	hsa-miR-2115	CLIP-seq
MIRT1075543	hsa-miR-24	CLIP-seq
MIRT1075653	hsa-miR-26a	CLIP-seq
MIRT1075654	hsa-miR-26b	CLIP-seq
MIRT2250654	hsa-miR-2861	CLIP-seq
MIRT1075544	hsa-miR-301a	CLIP-seq
MIRT1075545	hsa-miR-301b	CLIP-seq
MIRT2018776	hsa-miR-302a	CLIP-seq
MIRT2018777	hsa-miR-302b	CLIP-seq
MIRT2018778	hsa-miR-302c	CLIP-seq
MIRT2018779	hsa-miR-302d	CLIP-seq
MIRT2018780	hsa-miR-302e	CLIP-seq
MIRT1075546	hsa-miR-3135b	CLIP-seq
MIRT1075657	hsa-miR-3158-3p	CLIP-seq
MIRT2250655	hsa-miR-3189-5p	CLIP-seq
MIRT2250656	hsa-miR-3197	CLIP-seq
MIRT1075562	hsa-miR-320e	CLIP-seq
MIRT2250657	hsa-miR-323-5p	CLIP-seq
MIRT1075563	hsa-miR-324-3p	CLIP-seq
MIRT1075566	hsa-miR-3545-3p	CLIP-seq
MIRT2018786	hsa-miR-3650	CLIP-seq
MIRT1075568	hsa-miR-3652	CLIP-seq
MIRT2250658	hsa-miR-3664-5p	CLIP-seq
MIRT1075571	hsa-miR-3666	CLIP-seq
MIRT2250659	hsa-miR-3672	CLIP-seq
MIRT1075661	hsa-miR-3691-3p	CLIP-seq
MIRT2250660	hsa-miR-3692	CLIP-seq
MIRT1075662	hsa-miR-370	CLIP-seq
MIRT2018787	hsa-miR-372	CLIP-seq
MIRT2018788	hsa-miR-373	CLIP-seq
MIRT1075580	hsa-miR-4279	CLIP-seq
MIRT1075581	hsa-miR-4284	CLIP-seq
MIRT1075583	hsa-miR-4295	CLIP-seq
MIRT2250661	hsa-miR-4312	CLIP-seq
MIRT2250662	hsa-miR-4423-5p	CLIP-seq
MIRT1075590	hsa-miR-4430	CLIP-seq
MIRT2250663	hsa-miR-4463	CLIP-seq
MIRT1075669	hsa-miR-4465	CLIP-seq
MIRT2250664	hsa-miR-4483	CLIP-seq
MIRT2250665	hsa-miR-4494	CLIP-seq
MIRT2250666	hsa-miR-4512	CLIP-seq
MIRT2250667	hsa-miR-4520a-3p	CLIP-seq
MIRT2250668	hsa-miR-4520b-3p	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT1075598	hsa-miR-454	CLIP-seq
MIRT2250669	hsa-miR-4634	CLIP-seq
MIRT2250670	hsa-miR-4639-3p	CLIP-seq
MIRT2250671	hsa-miR-4695-3p	CLIP-seq
MIRT1075610	hsa-miR-4707-3p	CLIP-seq
MIRT1075611	hsa-miR-4715-3p	CLIP-seq
MIRT1075613	hsa-miR-4722-3p	CLIP-seq
MIRT2018795	hsa-miR-4731-5p	CLIP-seq
MIRT2250672	hsa-miR-4757-5p	CLIP-seq
MIRT1075617	hsa-miR-4763-5p	CLIP-seq
MIRT1075618	hsa-miR-4772-3p	CLIP-seq
MIRT1075622	hsa-miR-4781-3p	CLIP-seq
MIRT2018799	hsa-miR-4795-3p	CLIP-seq
MIRT2250673	hsa-miR-4797-5p	CLIP-seq
MIRT1075628	hsa-miR-498	CLIP-seq
MIRT1075629	hsa-miR-5096	CLIP-seq
MIRT2018801	hsa-miR-512-3p	CLIP-seq
MIRT1075678	hsa-miR-516a-3p	CLIP-seq
MIRT2018803	hsa-miR-519d	CLIP-seq
MIRT2018804	hsa-miR-520a-3p	CLIP-seq
MIRT2018805	hsa-miR-520b	CLIP-seq
MIRT2018806	hsa-miR-520c-3p	CLIP-seq
MIRT2018807	hsa-miR-520d-3p	CLIP-seq
MIRT2018808	hsa-miR-520e	CLIP-seq
MIRT2018809	hsa-miR-520g	CLIP-seq
MIRT2018810	hsa-miR-520h	CLIP-seq
MIRT1075680	hsa-miR-552	CLIP-seq
MIRT2250674	hsa-miR-562	CLIP-seq
MIRT2250675	hsa-miR-652	CLIP-seq
MIRT1075684	hsa-miR-891a	CLIP-seq
MIRT2018814	hsa-miR-93	CLIP-seq
MIRT1075543	hsa-miR-24	CLIP-seq
MIRT1075581	hsa-miR-4284	CLIP-seq
MIRT2389533	hsa-miR-4515	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT2250673	hsa-miR-4797-5p	CLIP-seq
MIRT1075628	hsa-miR-498	CLIP-seq
MIRT1075516	hsa-miR-1200	CLIP-seq
MIRT1075517	hsa-miR-122	CLIP-seq
MIRT1075645	hsa-miR-1297	CLIP-seq
MIRT1075538	hsa-miR-1976	CLIP-seq
MIRT1075653	hsa-miR-26a	CLIP-seq
MIRT1075654	hsa-miR-26b	CLIP-seq
MIRT1075546	hsa-miR-3135b	CLIP-seq
MIRT2452050	hsa-miR-331-3p	CLIP-seq
MIRT1075568	hsa-miR-3652	CLIP-seq
MIRT1075569	hsa-miR-3655	CLIP-seq
MIRT2452051	hsa-miR-374c	CLIP-seq
MIRT1075575	hsa-miR-4252	CLIP-seq
MIRT1075580	hsa-miR-4279	CLIP-seq
MIRT1075586	hsa-miR-4324	CLIP-seq
MIRT1075590	hsa-miR-4430	CLIP-seq
MIRT1075669	hsa-miR-4465	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT1075605	hsa-miR-4691-3p	CLIP-seq
MIRT1075608	hsa-miR-4698	CLIP-seq
MIRT2452052	hsa-miR-4709-3p	CLIP-seq
MIRT1075613	hsa-miR-4722-3p	CLIP-seq
MIRT1075615	hsa-miR-4735-5p	CLIP-seq
MIRT1075623	hsa-miR-4794	CLIP-seq
MIRT1075628	hsa-miR-498	CLIP-seq
MIRT1075631	hsa-miR-544b	CLIP-seq
MIRT2452053	hsa-miR-655	CLIP-seq
MIRT2452054	hsa-miR-767-5p	CLIP-seq
MIRT1075640	hsa-miR-885-3p	CLIP-seq
MIRT1075516	hsa-miR-1200	CLIP-seq
MIRT2018768	hsa-miR-1207-3p	CLIP-seq
MIRT2018769	hsa-miR-1207-5p	CLIP-seq
MIRT1075517	hsa-miR-122	CLIP-seq
MIRT1075519	hsa-miR-1228	CLIP-seq
MIRT1075643	hsa-miR-1234	CLIP-seq
MIRT2554148	hsa-miR-1285	CLIP-seq
MIRT1075522	hsa-miR-1286	CLIP-seq
MIRT1075645	hsa-miR-1297	CLIP-seq
MIRT2554149	hsa-miR-1322	CLIP-seq
MIRT2018771	hsa-miR-150	CLIP-seq
MIRT2554150	hsa-miR-1538	CLIP-seq
MIRT1075536	hsa-miR-1913	CLIP-seq
MIRT1075537	hsa-miR-197	CLIP-seq
MIRT1075538	hsa-miR-1976	CLIP-seq
MIRT2554151	hsa-miR-204	CLIP-seq
MIRT2554152	hsa-miR-211	CLIP-seq
MIRT2250643	hsa-miR-2278	CLIP-seq
MIRT1075543	hsa-miR-24	CLIP-seq
MIRT1075653	hsa-miR-26a	CLIP-seq
MIRT1075654	hsa-miR-26b	CLIP-seq
MIRT2250654	hsa-miR-2861	CLIP-seq
MIRT1075546	hsa-miR-3135b	CLIP-seq
MIRT2018782	hsa-miR-3149	CLIP-seq
MIRT1075547	hsa-miR-3152-5p	CLIP-seq
MIRT2554153	hsa-miR-3153	CLIP-seq
MIRT2554154	hsa-miR-3187-5p	CLIP-seq
MIRT1075562	hsa-miR-320e	CLIP-seq
MIRT1075563	hsa-miR-324-3p	CLIP-seq
MIRT2250644	hsa-miR-335	CLIP-seq
MIRT2018786	hsa-miR-3650	CLIP-seq
MIRT1075568	hsa-miR-3652	CLIP-seq
MIRT2554155	hsa-miR-3675-3p	CLIP-seq
MIRT2554156	hsa-miR-3689a-3p	CLIP-seq
MIRT2554157	hsa-miR-3689c	CLIP-seq
MIRT1075662	hsa-miR-370	CLIP-seq
MIRT2554158	hsa-miR-3938	CLIP-seq
MIRT2018789	hsa-miR-411	CLIP-seq
MIRT2554159	hsa-miR-4265	CLIP-seq
MIRT1075580	hsa-miR-4279	CLIP-seq
MIRT1075581	hsa-miR-4284	CLIP-seq
MIRT2554160	hsa-miR-4296	CLIP-seq
MIRT2554161	hsa-miR-4300	CLIP-seq
MIRT2554162	hsa-miR-4322	CLIP-seq
MIRT1075586	hsa-miR-4324	CLIP-seq
MIRT1075587	hsa-miR-4330	CLIP-seq
MIRT2554163	hsa-miR-4417	CLIP-seq
MIRT1075590	hsa-miR-4430	CLIP-seq
MIRT2554164	hsa-miR-4434	CLIP-seq
MIRT1075592	hsa-miR-4452	CLIP-seq
MIRT2554165	hsa-miR-4459	CLIP-seq
MIRT1075669	hsa-miR-4465	CLIP-seq
MIRT1075595	hsa-miR-4488	CLIP-seq
MIRT2250666	hsa-miR-4512	CLIP-seq
MIRT2554166	hsa-miR-4516	CLIP-seq
MIRT2554167	hsa-miR-4531	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT2554168	hsa-miR-4641	CLIP-seq
MIRT2018793	hsa-miR-4650-5p	CLIP-seq
MIRT2554169	hsa-miR-4668-5p	CLIP-seq
MIRT2554170	hsa-miR-4684-5p	CLIP-seq
MIRT1075607	hsa-miR-4697-5p	CLIP-seq
MIRT1075608	hsa-miR-4698	CLIP-seq
MIRT1075610	hsa-miR-4707-3p	CLIP-seq
MIRT1075611	hsa-miR-4715-3p	CLIP-seq
MIRT2554171	hsa-miR-4717-5p	CLIP-seq
MIRT1075613	hsa-miR-4722-3p	CLIP-seq
MIRT1075614	hsa-miR-4722-5p	CLIP-seq
MIRT2018796	hsa-miR-4733-3p	CLIP-seq
MIRT1075615	hsa-miR-4735-5p	CLIP-seq
MIRT2554172	hsa-miR-4737	CLIP-seq
MIRT2554173	hsa-miR-4745-3p	CLIP-seq
MIRT2554174	hsa-miR-4747-3p	CLIP-seq
MIRT2554175	hsa-miR-4752	CLIP-seq
MIRT2554176	hsa-miR-4753-5p	CLIP-seq
MIRT2554177	hsa-miR-4755-5p	CLIP-seq
MIRT2018798	hsa-miR-4763-3p	CLIP-seq
MIRT1075617	hsa-miR-4763-5p	CLIP-seq
MIRT1075619	hsa-miR-4774-3p	CLIP-seq
MIRT1075620	hsa-miR-4775	CLIP-seq
MIRT2554178	hsa-miR-4779	CLIP-seq
MIRT1075623	hsa-miR-4794	CLIP-seq
MIRT2250673	hsa-miR-4797-5p	CLIP-seq
MIRT1075628	hsa-miR-498	CLIP-seq
MIRT1075629	hsa-miR-5096	CLIP-seq
MIRT1075631	hsa-miR-544b	CLIP-seq
MIRT1075680	hsa-miR-552	CLIP-seq
MIRT1075634	hsa-miR-590-3p	CLIP-seq
MIRT1075635	hsa-miR-596	CLIP-seq
MIRT2554179	hsa-miR-604	CLIP-seq
MIRT2554180	hsa-miR-612	CLIP-seq
MIRT2554181	hsa-miR-623	CLIP-seq
MIRT2554182	hsa-miR-646	CLIP-seq
MIRT2554183	hsa-miR-660	CLIP-seq
MIRT2554184	hsa-miR-720	CLIP-seq
MIRT2554185	hsa-miR-920	CLIP-seq
MIRT1075516	hsa-miR-1200	CLIP-seq
MIRT2018768	hsa-miR-1207-3p	CLIP-seq
MIRT2018769	hsa-miR-1207-5p	CLIP-seq
MIRT1075517	hsa-miR-122	CLIP-seq
MIRT1075519	hsa-miR-1228	CLIP-seq
MIRT2250647	hsa-miR-1245	CLIP-seq
MIRT2554148	hsa-miR-1285	CLIP-seq
MIRT1075645	hsa-miR-1297	CLIP-seq
MIRT1075526	hsa-miR-130a	CLIP-seq
MIRT1075527	hsa-miR-130b	CLIP-seq
MIRT2554149	hsa-miR-1322	CLIP-seq
MIRT2683071	hsa-miR-146a	CLIP-seq
MIRT2683072	hsa-miR-146b-5p	CLIP-seq
MIRT2554150	hsa-miR-1538	CLIP-seq
MIRT1075528	hsa-miR-1539	CLIP-seq
MIRT1075536	hsa-miR-1913	CLIP-seq
MIRT1075537	hsa-miR-197	CLIP-seq
MIRT1075538	hsa-miR-1976	CLIP-seq
MIRT2554151	hsa-miR-204	CLIP-seq
MIRT2554152	hsa-miR-211	CLIP-seq
MIRT2683073	hsa-miR-2276	CLIP-seq
MIRT2250643	hsa-miR-2278	CLIP-seq
MIRT1075543	hsa-miR-24	CLIP-seq
MIRT1075653	hsa-miR-26a	CLIP-seq
MIRT1075654	hsa-miR-26b	CLIP-seq
MIRT2250654	hsa-miR-2861	CLIP-seq
MIRT1075544	hsa-miR-301a	CLIP-seq
MIRT1075545	hsa-miR-301b	CLIP-seq
MIRT2683074	hsa-miR-3129-3p	CLIP-seq
MIRT1075546	hsa-miR-3135b	CLIP-seq
MIRT2018782	hsa-miR-3149	CLIP-seq
MIRT1075547	hsa-miR-3152-5p	CLIP-seq
MIRT2554153	hsa-miR-3153	CLIP-seq
MIRT1075551	hsa-miR-3159	CLIP-seq
MIRT1075552	hsa-miR-3162-5p	CLIP-seq
MIRT2683075	hsa-miR-3183	CLIP-seq
MIRT1075658	hsa-miR-3187-3p	CLIP-seq
MIRT2554154	hsa-miR-3187-5p	CLIP-seq
MIRT1075555	hsa-miR-3193	CLIP-seq
MIRT1075562	hsa-miR-320e	CLIP-seq
MIRT1075563	hsa-miR-324-3p	CLIP-seq
MIRT2250644	hsa-miR-335	CLIP-seq
MIRT2018786	hsa-miR-3650	CLIP-seq
MIRT1075568	hsa-miR-3652	CLIP-seq
MIRT1075569	hsa-miR-3655	CLIP-seq
MIRT1075571	hsa-miR-3666	CLIP-seq
MIRT2683076	hsa-miR-3667-3p	CLIP-seq
MIRT2554155	hsa-miR-3675-3p	CLIP-seq
MIRT2554156	hsa-miR-3689a-3p	CLIP-seq
MIRT2554157	hsa-miR-3689c	CLIP-seq
MIRT1075662	hsa-miR-370	CLIP-seq
MIRT2554158	hsa-miR-3938	CLIP-seq
MIRT2683077	hsa-miR-3942-3p	CLIP-seq
MIRT2018789	hsa-miR-411	CLIP-seq
MIRT2554159	hsa-miR-4265	CLIP-seq
MIRT1075580	hsa-miR-4279	CLIP-seq
MIRT1075581	hsa-miR-4284	CLIP-seq
MIRT1075583	hsa-miR-4295	CLIP-seq
MIRT2554160	hsa-miR-4296	CLIP-seq
MIRT2554161	hsa-miR-4300	CLIP-seq
MIRT2250661	hsa-miR-4312	CLIP-seq
MIRT2554162	hsa-miR-4322	CLIP-seq
MIRT1075586	hsa-miR-4324	CLIP-seq
MIRT1075587	hsa-miR-4330	CLIP-seq
MIRT2554163	hsa-miR-4417	CLIP-seq
MIRT2250662	hsa-miR-4423-5p	CLIP-seq
MIRT1075590	hsa-miR-4430	CLIP-seq
MIRT2554164	hsa-miR-4434	CLIP-seq
MIRT1075668	hsa-miR-4435	CLIP-seq
MIRT2683078	hsa-miR-4446-3p	CLIP-seq
MIRT1075592	hsa-miR-4452	CLIP-seq
MIRT2554165	hsa-miR-4459	CLIP-seq
MIRT1075669	hsa-miR-4465	CLIP-seq
MIRT2250666	hsa-miR-4512	CLIP-seq
MIRT2554166	hsa-miR-4516	CLIP-seq
MIRT2554167	hsa-miR-4531	CLIP-seq
MIRT1075597	hsa-miR-4532	CLIP-seq
MIRT1075598	hsa-miR-454	CLIP-seq
MIRT2250669	hsa-miR-4634	CLIP-seq
MIRT2554168	hsa-miR-4641	CLIP-seq
MIRT2018793	hsa-miR-4650-5p	CLIP-seq
MIRT2683079	hsa-miR-4656	CLIP-seq
MIRT2554169	hsa-miR-4668-5p	CLIP-seq
MIRT2554170	hsa-miR-4684-5p	CLIP-seq
MIRT2250671	hsa-miR-4695-3p	CLIP-seq
MIRT1075608	hsa-miR-4698	CLIP-seq
MIRT1075671	hsa-miR-4701-5p	CLIP-seq
MIRT1075610	hsa-miR-4707-3p	CLIP-seq
MIRT2452052	hsa-miR-4709-3p	CLIP-seq
MIRT2683080	hsa-miR-4714-3p	CLIP-seq
MIRT1075611	hsa-miR-4715-3p	CLIP-seq
MIRT2554171	hsa-miR-4717-5p	CLIP-seq
MIRT1075613	hsa-miR-4722-3p	CLIP-seq
MIRT1075614	hsa-miR-4722-5p	CLIP-seq
MIRT2683081	hsa-miR-4723-3p	CLIP-seq
MIRT2683082	hsa-miR-4724-3p	CLIP-seq
MIRT2018796	hsa-miR-4733-3p	CLIP-seq
MIRT1075615	hsa-miR-4735-5p	CLIP-seq
MIRT2554172	hsa-miR-4737	CLIP-seq
MIRT2554173	hsa-miR-4745-3p	CLIP-seq
MIRT2554174	hsa-miR-4747-3p	CLIP-seq
MIRT2554175	hsa-miR-4752	CLIP-seq
MIRT2554176	hsa-miR-4753-5p	CLIP-seq
MIRT2554177	hsa-miR-4755-5p	CLIP-seq
MIRT2250672	hsa-miR-4757-5p	CLIP-seq
MIRT1075616	hsa-miR-4760-3p	CLIP-seq
MIRT2018798	hsa-miR-4763-3p	CLIP-seq
MIRT1075617	hsa-miR-4763-5p	CLIP-seq
MIRT1075619	hsa-miR-4774-3p	CLIP-seq
MIRT1075620	hsa-miR-4775	CLIP-seq
MIRT2554178	hsa-miR-4779	CLIP-seq
MIRT2683083	hsa-miR-4786-5p	CLIP-seq
MIRT1075623	hsa-miR-4794	CLIP-seq
MIRT2250673	hsa-miR-4797-5p	CLIP-seq
MIRT1075624	hsa-miR-486-5p	CLIP-seq
MIRT1075626	hsa-miR-490-3p	CLIP-seq
MIRT1075628	hsa-miR-498	CLIP-seq
MIRT1075629	hsa-miR-5096	CLIP-seq
MIRT2683084	hsa-miR-520a-5p	CLIP-seq
MIRT2683085	hsa-miR-525-5p	CLIP-seq
MIRT1075631	hsa-miR-544b	CLIP-seq
MIRT1075679	hsa-miR-548s	CLIP-seq
MIRT1075681	hsa-miR-588	CLIP-seq
MIRT1075634	hsa-miR-590-3p	CLIP-seq
MIRT1075635	hsa-miR-596	CLIP-seq
MIRT2554179	hsa-miR-604	CLIP-seq
MIRT2554180	hsa-miR-612	CLIP-seq
MIRT2554181	hsa-miR-623	CLIP-seq
MIRT2554182	hsa-miR-646	CLIP-seq
MIRT1075637	hsa-miR-649	CLIP-seq
MIRT2250675	hsa-miR-652	CLIP-seq
MIRT2554183	hsa-miR-660	CLIP-seq
MIRT2554184	hsa-miR-720	CLIP-seq
MIRT2683086	hsa-miR-769-5p	CLIP-seq
MIRT2554185	hsa-miR-920	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003995	Function	Acyl-CoA dehydrogenase activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0005759	Component	Mitochondrial matrix	IEA
GO:0005759	Component	Mitochondrial matrix	ISS
GO:0005759	Component	Mitochondrial matrix	NAS	2063866
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0006552	Process	L-leucine catabolic process	IBA
GO:0006552	Process	L-leucine catabolic process	IDA	7640268
GO:0006552	Process	L-leucine catabolic process	IEA
GO:0006552	Process	L-leucine catabolic process	ISS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0008470	Function	3-methylbutanoyl-CoA dehydrogenase activity	IBA
GO:0008470	Function	3-methylbutanoyl-CoA dehydrogenase activity	IDA	3597357, 7640268
GO:0008470	Function	3-methylbutanoyl-CoA dehydrogenase activity	IEA
GO:0008470	Function	3-methylbutanoyl-CoA dehydrogenase activity	ISS
GO:0008470	Function	3-methylbutanoyl-CoA dehydrogenase activity	TAS	3446585
GO:0009083	Process	Branched-chain amino acid catabolic process	IDA	7640268
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016627	Function	Oxidoreductase activity, acting on the CH-CH group of donors	IEA
GO:0016937	Function	Short-chain fatty acyl-CoA dehydrogenase activity	IEA
GO:0033539	Process	Fatty acid beta-oxidation using acyl-CoA dehydrogenase	IDA	3597357
GO:0042802	Function	Identical protein binding	ISS
GO:0050660	Function	Flavin adenine dinucleotide binding	IEA

Other IDs

• MIM: 607036
• HGNC: 6186
• e!Ensembl: ENSG00000128928

Protein

• UniProt ID: P26440
• Protein name: Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) (Butyryl-CoA dehydrogenase) (EC 1.3.8.1)
• Protein function: Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway (PubMed:7640268). To a lesser extent, is also able to catalyze the oxidation of other satur
• PDB: 1IVH, 8SGR
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02771	Acyl-CoA_dh_N	46 → 160	Acyl-CoA dehydrogenase, N-terminal domain	Domain
  PF02770	Acyl-CoA_dh_M	164 → 261	Acyl-CoA dehydrogenase, middle domain	Domain
  PF00441	Acyl-CoA_dh_1	273 → 421	Acyl-CoA dehydrogenase, C-terminal domain	Domain

• Sequence:

  MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
  QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
  ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
  LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
  KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
  VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
  AGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA
  FNADFH

• Sequence length: 426

Pathways

KEGG:

Valine, leucine and isoleucine degradation
Metabolic pathways

Reactome:

Branched-chain amino acid catabolism

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Cervical cancer	Likely pathogenic; Pathogenic	rs1477527791	RCV005900151	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Isovaleric acidemia, type I	Pathogenic; Likely pathogenic	rs121434284, rs121434285	RCV000003743 RCV000003744	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Isovaleric acidemia, type III	Likely pathogenic; Pathogenic	rs786204613	RCV002284192	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Isovaleryl-CoA dehydrogenase deficiency	Likely pathogenic; Pathogenic	rs1221254988, rs771914739, rs1057517056, rs1193235415, rs878909737, rs2141290050, rs2141304438, rs544110604, rs781340220, rs2141332040, rs2141289961, rs2141332016, rs2141301396, rs2141329244, rs1891640609, rs2141351682, rs763665120, rs2141302044, rs767782379, rs2141332035, rs2542620925, rs142761835, rs2542697378, rs757351801, rs2542714217, rs1199952317, rs2542713682, rs2542737883, rs2542691558, rs2542649462, rs2542649798, rs2542681353, rs981444721, rs2542697546, rs121434285, rs34695403, rs28940889, rs2229311, rs786204427, rs786204613, rs1462096457, rs552272986, rs2542783643, rs763471771, rs747273828, rs748026507, rs796051983, rs1355297002, rs1566940436, rs2542737140, rs371427844, rs146861563, rs368705240, rs1891052909, rs2542618992, rs1566943451, rs2542782727, rs2542756668, rs2542748614, rs2141322944, rs1319705053, rs747807491, rs1566935193, rs2542759702, rs2542747913, rs2542738169, rs2542696243, rs1241965322, rs2542739685, rs2542760189, rs2542696391, rs1890974853, rs2542649911, rs2542648975, rs2542649345, rs2542650079, rs2542714477, rs928991928, rs1443916294, rs2542783787, rs2542698306, rs2542698265, rs144099251, rs2542737278, rs2542756101, rs760307260, rs2542739501, rs2542679335, rs2542737808, rs1057517379, rs765815516, rs1057517043, rs1057516769, rs773560012, rs1555404010, rs1314850102, rs759159766, rs1555403942, rs769048174, rs781630355, rs1477527791, rs763422682, rs907414760, rs776015412, rs1555405067, rs1555405428, rs1398838997, rs1555404784, rs1555403211, rs1555404426, rs745629936, rs1555405070, rs1555405080, rs398123681, rs1566936542, rs1364046355, rs982218848, rs1595786853, rs754600862, rs540375168, rs776608445, rs1595797766, rs1237032588, rs1890343709, rs568885234, rs1891639284, rs745464766, rs1891674455, rs1890589984, rs199865931, rs398123682, rs398123683, rs398123684	RCV001366950 RCV001378700 RCV001378050 RCV001377640 RCV004798914 RCV001782321 RCV001782322 RCV002542366 RCV001823529 RCV002030902 RCV001939420 RCV002005384 RCV002044763 RCV001884650 RCV001976611 RCV001994636 RCV001922350 RCV001941546 RCV001943987 RCV002008952 RCV002283641 RCV000169054 RCV002306513 RCV002309560 RCV002309913 RCV002307866 RCV002307911 RCV002308197 RCV002309046 RCV002309312 RCV002306968 RCV002307022 RCV002307196 RCV002310212 RCV000984276 RCV000003748 RCV000003749 RCV000169289 RCV000169022 RCV000169016 RCV000169373 RCV003041220 RCV003041221 RCV002628309 RCV000762946 RCV001779516 RCV001376756 RCV000412245 RCV003009102 RCV003146747 RCV003146754 RCV003226014 RCV001004404 RCV000674322 RCV001859652 RCV003324447 RCV003469872 RCV003469873 RCV003461756 RCV003461757 RCV003461758 RCV003461759 RCV003461761 RCV003461762 RCV003461763 RCV003461764 RCV003469875 RCV003469876 RCV003469877 RCV003461765 RCV003469878 RCV003461766 RCV003461767 RCV003501187 RCV003501725 RCV003501717 RCV003500429 RCV003607827 RCV003607933 RCV003607931 RCV003608138 RCV003608090 RCV003608267 RCV003608404 RCV003607074 RCV003831395 RCV003843743 RCV003873563 RCV003872181 RCV003990890 RCV004576765 RCV004576766 RCV000409035 RCV000412035 RCV000411182 RCV000410639 RCV000410323 RCV000408999 RCV000409066 RCV000412119 RCV003144292 RCV000540901 RCV000555769 RCV000527532 RCV000546725 RCV000526058 RCV000634868 RCV000634867 RCV000665281 RCV000666222 RCV000674343 RCV000666290 RCV000667869 RCV000673634 RCV000665831 RCV000665469 RCV000667342 RCV000668022 RCV000668527 RCV000692024 RCV000714868 RCV004569413 RCV000761533 RCV000984025 RCV000800024 RCV000808800 RCV000989288 RCV000989289 RCV000989290 RCV001056208 RCV001071786 RCV001060066 RCV001070596 RCV001070595 RCV001047853 RCV001170022 RCV001230646 RCV001239347 RCV000178176 RCV000178177 RCV000178862	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
IVD-related disorder	Likely pathogenic; Pathogenic	rs142761835, rs28940889, rs2229311, rs2542679317	RCV003416000 RCV003952534 RCV003927565 RCV003391566	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Melanoma	Likely pathogenic	rs757351801	RCV005931792	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AMINO ACID METABOLISM, INBORN ERRORS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ANDROGENETIC ALOPECIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IDIOPATHIC PULMONARY FIBROSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTERSTITIAL LUNG DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SECONDARY MALIGNANT NEOPLASM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Arteriosclerosis	Arteriosclerosis	BEFREE	31751427		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	31751427		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	21122130		★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	20519759	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	31201565		★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
HYPERGLYCINURIA (disorder)	Hyperglycinuria	HPO_DG			★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Idiopathic pulmonary fibrosis	Pubtator	25275363, 31339356	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Intervertebral Disc Degeneration	Intervertebral Disc Degeneration	BEFREE	26162271, 28665183, 31201565		★☆☆☆☆ Found in Text Mining only
Isovaleric acidemia	Isovaleric Acidemia	Orphanet			★☆☆☆☆ Found in Text Mining only
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	BEFREE	10677295, 10713113, 1310317, 16602101, 17027310, 17576084, 20519759, 21040472, 22960500, 23063737, 23587913, 26018748, 30709776, 31707166, 3863140, 9665741		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	CLINVAR_DG	10677295, 10713113, 1310317, 15337167, 15486829, 16602101, 16825284, 17027310, 17576084, 19099814, 20519759, 2063866, 22004070, 22350545, 22960500, 2318964, 23587913, 24516753, 24637313, 25220015, 26018748, 26937393, 27629047, 27904153, 9665741		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	GENOMICS_ENGLAND_DG	1310317, 24019846, 24816252		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	CLINGEN_DG	16602101, 2063866, 24019846, 27904153, 30709776, 6630517		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	UNIPROT_DG	2063866, 22004070, 22350545, 23587913, 28535199, 9665741		★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	CTD_human_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Isovaleryl-CoA dehydrogenase deficiency	Isovaleryl-CoA dehydrogenase deficiency	ORPHANET_DG			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Ketosis	Ketosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Ketosis	Ketosis	CLINVAR_DG			★☆☆☆☆ Found in Text Mining only
Leukopenia	Leukopenia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Lung Diseases, Interstitial	Lung Diseases	GWASDB_DG	23583980		★☆☆☆☆ Found in Text Mining only
Lung Diseases, Interstitial	Lung Diseases	GWASCAT_DG	23583980		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31316555		★☆☆☆☆ Found in Text Mining only
Metabolic Diseases	Metabolic Diseases	BEFREE	23587913		★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	GWASDB_DG	21211798		★☆☆☆☆ Found in Text Mining only
Pancytopenia	Pancytopenia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	25275363		★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary fibrosis	Pubtator	25275363, 37930192	Associate	★☆☆☆☆ Found in Text Mining only
Vaginitis	Vaginitis	BEFREE	31748322		★☆☆☆☆ Found in Text Mining only