ITPKB (inositol-trisphosphate 3-kinase B)

Gene

• Entrez ID: 3707
• Gene name: Inositol-trisphosphate 3-kinase B
• Gene symbol: ITPKB
• Synonyms (NCBI Gene): IP3-3KB, IP3K, IP3K-B, IP3KB, PIG37
• Chromosome: 1
• Chromosome location: 1q42.12
• Summary: The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large num

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT047075	hsa-miR-183-5p	CLASH	23622248
MIRT045004	hsa-miR-186-5p	CLASH	23622248
MIRT719365	hsa-miR-941	HITS-CLIP	19536157
MIRT719364	hsa-miR-3914	HITS-CLIP	19536157
MIRT719363	hsa-miR-873-5p	HITS-CLIP	19536157
MIRT719362	hsa-miR-331-3p	HITS-CLIP	19536157
MIRT719360	hsa-miR-4292	HITS-CLIP	19536157
MIRT719361	hsa-miR-6791-5p	HITS-CLIP	19536157
MIRT719359	hsa-miR-6850-3p	HITS-CLIP	19536157
MIRT719358	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT719357	hsa-miR-378g	HITS-CLIP	19536157
MIRT719356	hsa-miR-4313	HITS-CLIP	19536157
MIRT719355	hsa-miR-4437	HITS-CLIP	19536157
MIRT719354	hsa-miR-4674	HITS-CLIP	19536157
MIRT623570	hsa-miR-8485	HITS-CLIP	23824327
MIRT623569	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT623568	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT623567	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT623566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623562	hsa-miR-133b	HITS-CLIP	23824327
MIRT623570	hsa-miR-8485	HITS-CLIP	23824327
MIRT623569	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT623568	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT623567	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT623566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT623565	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623564	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623562	hsa-miR-133b	HITS-CLIP	23824327
MIRT536591	hsa-miR-410-3p	PAR-CLIP	22012620
MIRT536590	hsa-miR-548aa	PAR-CLIP	22012620
MIRT536589	hsa-miR-548ap-3p	PAR-CLIP	22012620
MIRT536588	hsa-miR-548t-3p	PAR-CLIP	22012620
MIRT536587	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT536586	hsa-miR-548at-3p	PAR-CLIP	22012620
MIRT536585	hsa-miR-548ay-3p	PAR-CLIP	22012620
MIRT536584	hsa-miR-590-3p	PAR-CLIP	22012620
MIRT536583	hsa-miR-3065-5p	PAR-CLIP	22012620
MIRT440418	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440417	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440418	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727415	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727416	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727414	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727413	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440417	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT719365	hsa-miR-941	HITS-CLIP	19536157
MIRT719364	hsa-miR-3914	HITS-CLIP	19536157
MIRT719363	hsa-miR-873-5p	HITS-CLIP	19536157
MIRT719362	hsa-miR-331-3p	HITS-CLIP	19536157
MIRT719360	hsa-miR-4292	HITS-CLIP	19536157
MIRT719361	hsa-miR-6791-5p	HITS-CLIP	19536157
MIRT719359	hsa-miR-6850-3p	HITS-CLIP	19536157
MIRT719358	hsa-miR-939-3p	HITS-CLIP	19536157
MIRT719357	hsa-miR-378g	HITS-CLIP	19536157
MIRT719356	hsa-miR-4313	HITS-CLIP	19536157
MIRT719355	hsa-miR-4437	HITS-CLIP	19536157
MIRT719354	hsa-miR-4674	HITS-CLIP	19536157
MIRT623570	hsa-miR-8485	HITS-CLIP	23824327
MIRT623569	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT623568	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT623567	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT623566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623562	hsa-miR-133b	HITS-CLIP	23824327
MIRT623570	hsa-miR-8485	HITS-CLIP	23824327
MIRT623569	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT623568	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT623567	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT623566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT623565	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623564	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623563	hsa-miR-133a-3p	HITS-CLIP	23824327
MIRT623562	hsa-miR-133b	HITS-CLIP	23824327
MIRT536591	hsa-miR-410-3p	PAR-CLIP	22012620
MIRT536590	hsa-miR-548aa	PAR-CLIP	22012620
MIRT536589	hsa-miR-548ap-3p	PAR-CLIP	22012620
MIRT536588	hsa-miR-548t-3p	PAR-CLIP	22012620
MIRT536587	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT536586	hsa-miR-548at-3p	PAR-CLIP	22012620
MIRT536585	hsa-miR-548ay-3p	PAR-CLIP	22012620
MIRT536584	hsa-miR-590-3p	PAR-CLIP	22012620
MIRT536583	hsa-miR-3065-5p	PAR-CLIP	22012620
MIRT1074811	hsa-miR-106a	CLIP-seq
MIRT1074812	hsa-miR-106b	CLIP-seq
MIRT1074813	hsa-miR-1207-3p	CLIP-seq
MIRT1074814	hsa-miR-1252	CLIP-seq
MIRT1074815	hsa-miR-125a-3p	CLIP-seq
MIRT1074816	hsa-miR-1281	CLIP-seq
MIRT1074817	hsa-miR-1322	CLIP-seq
MIRT1074818	hsa-miR-1323	CLIP-seq
MIRT1074819	hsa-miR-135a	CLIP-seq
MIRT1074820	hsa-miR-135b	CLIP-seq
MIRT1074821	hsa-miR-138	CLIP-seq
MIRT1074822	hsa-miR-146b-3p	CLIP-seq
MIRT1074823	hsa-miR-150	CLIP-seq
MIRT1074824	hsa-miR-153	CLIP-seq
MIRT1074825	hsa-miR-17	CLIP-seq
MIRT1074826	hsa-miR-20a	CLIP-seq
MIRT1074827	hsa-miR-20b	CLIP-seq
MIRT1074828	hsa-miR-219-1-3p	CLIP-seq
MIRT1074829	hsa-miR-2355-5p	CLIP-seq
MIRT1074830	hsa-miR-27a	CLIP-seq
MIRT1074831	hsa-miR-27b	CLIP-seq
MIRT1074832	hsa-miR-302a	CLIP-seq
MIRT1074833	hsa-miR-302b	CLIP-seq
MIRT1074834	hsa-miR-302c	CLIP-seq
MIRT1074835	hsa-miR-302d	CLIP-seq
MIRT1074836	hsa-miR-302e	CLIP-seq
MIRT1074837	hsa-miR-3138	CLIP-seq
MIRT1074838	hsa-miR-3173-5p	CLIP-seq
MIRT1074839	hsa-miR-3187-3p	CLIP-seq
MIRT1074840	hsa-miR-3192	CLIP-seq
MIRT1074841	hsa-miR-326	CLIP-seq
MIRT1074842	hsa-miR-330-5p	CLIP-seq
MIRT1074843	hsa-miR-342-5p	CLIP-seq
MIRT1074844	hsa-miR-346	CLIP-seq
MIRT1074845	hsa-miR-3609	CLIP-seq
MIRT1074846	hsa-miR-3688-5p	CLIP-seq
MIRT1074847	hsa-miR-3690	CLIP-seq
MIRT1074848	hsa-miR-372	CLIP-seq
MIRT1074849	hsa-miR-373	CLIP-seq
MIRT1074850	hsa-miR-375	CLIP-seq
MIRT1074851	hsa-miR-376a	CLIP-seq
MIRT1074852	hsa-miR-376b	CLIP-seq
MIRT1074853	hsa-miR-378	CLIP-seq
MIRT1074854	hsa-miR-378b	CLIP-seq
MIRT1074855	hsa-miR-378c	CLIP-seq
MIRT1074856	hsa-miR-378d	CLIP-seq
MIRT1074857	hsa-miR-378e	CLIP-seq
MIRT1074858	hsa-miR-378f	CLIP-seq
MIRT1074859	hsa-miR-378h	CLIP-seq
MIRT1074860	hsa-miR-378i	CLIP-seq
MIRT1074861	hsa-miR-383	CLIP-seq
MIRT1074862	hsa-miR-3919	CLIP-seq
MIRT1074863	hsa-miR-3925-5p	CLIP-seq
MIRT1074864	hsa-miR-3934	CLIP-seq
MIRT1074865	hsa-miR-422a	CLIP-seq
MIRT1074866	hsa-miR-4254	CLIP-seq
MIRT1074867	hsa-miR-4257	CLIP-seq
MIRT1074868	hsa-miR-4267	CLIP-seq
MIRT1074869	hsa-miR-4273	CLIP-seq
MIRT1074870	hsa-miR-4288	CLIP-seq
MIRT1074871	hsa-miR-4314	CLIP-seq
MIRT1074872	hsa-miR-4435	CLIP-seq
MIRT1074873	hsa-miR-4470	CLIP-seq
MIRT1074874	hsa-miR-448	CLIP-seq
MIRT1074875	hsa-miR-4493	CLIP-seq
MIRT1074876	hsa-miR-450b-5p	CLIP-seq
MIRT1074877	hsa-miR-4520a-3p	CLIP-seq
MIRT1074878	hsa-miR-4532	CLIP-seq
MIRT1074879	hsa-miR-4534	CLIP-seq
MIRT1074880	hsa-miR-455-3p	CLIP-seq
MIRT1074881	hsa-miR-4643	CLIP-seq
MIRT1074882	hsa-miR-4645-3p	CLIP-seq
MIRT1074883	hsa-miR-4646-5p	CLIP-seq
MIRT1074884	hsa-miR-4651	CLIP-seq
MIRT1074885	hsa-miR-466	CLIP-seq
MIRT1074886	hsa-miR-4664-5p	CLIP-seq
MIRT1074887	hsa-miR-4677-5p	CLIP-seq
MIRT1074888	hsa-miR-4698	CLIP-seq
MIRT1074889	hsa-miR-4701-5p	CLIP-seq
MIRT1074890	hsa-miR-4713-5p	CLIP-seq
MIRT1074891	hsa-miR-4717-3p	CLIP-seq
MIRT1074892	hsa-miR-4747-5p	CLIP-seq
MIRT1074893	hsa-miR-4749-3p	CLIP-seq
MIRT1074894	hsa-miR-4755-3p	CLIP-seq
MIRT1074895	hsa-miR-4756-3p	CLIP-seq
MIRT1074896	hsa-miR-4789-3p	CLIP-seq
MIRT1074897	hsa-miR-4789-5p	CLIP-seq
MIRT1074898	hsa-miR-4796-3p	CLIP-seq
MIRT1074899	hsa-miR-495	CLIP-seq
MIRT1074900	hsa-miR-513a-5p	CLIP-seq
MIRT1074901	hsa-miR-518a-5p	CLIP-seq
MIRT1074902	hsa-miR-519d	CLIP-seq
MIRT1074903	hsa-miR-520a-3p	CLIP-seq
MIRT1074904	hsa-miR-520b	CLIP-seq
MIRT1074905	hsa-miR-520c-3p	CLIP-seq
MIRT1074906	hsa-miR-520d-3p	CLIP-seq
MIRT1074907	hsa-miR-520e	CLIP-seq
MIRT1074908	hsa-miR-520f	CLIP-seq
MIRT1074909	hsa-miR-527	CLIP-seq
MIRT1074910	hsa-miR-532-3p	CLIP-seq
MIRT1074911	hsa-miR-548ah	CLIP-seq
MIRT1074912	hsa-miR-548an	CLIP-seq
MIRT1074913	hsa-miR-548o	CLIP-seq
MIRT1074914	hsa-miR-548s	CLIP-seq
MIRT1074915	hsa-miR-579	CLIP-seq
MIRT1074916	hsa-miR-588	CLIP-seq
MIRT1074917	hsa-miR-608	CLIP-seq
MIRT1074918	hsa-miR-632	CLIP-seq
MIRT1074919	hsa-miR-636	CLIP-seq
MIRT1074920	hsa-miR-664	CLIP-seq
MIRT1074921	hsa-miR-764	CLIP-seq
MIRT1074922	hsa-miR-767-3p	CLIP-seq
MIRT1074923	hsa-miR-874	CLIP-seq
MIRT1074924	hsa-miR-93	CLIP-seq
MIRT2018512	hsa-miR-1207-5p	CLIP-seq
MIRT1074814	hsa-miR-1252	CLIP-seq
MIRT2018513	hsa-miR-1285	CLIP-seq
MIRT2018514	hsa-miR-1289	CLIP-seq
MIRT2018515	hsa-miR-132	CLIP-seq
MIRT2018516	hsa-miR-1909	CLIP-seq
MIRT2018517	hsa-miR-194	CLIP-seq
MIRT2018518	hsa-miR-2114	CLIP-seq
MIRT2018519	hsa-miR-212	CLIP-seq
MIRT2018520	hsa-miR-224	CLIP-seq
MIRT1074830	hsa-miR-27a	CLIP-seq
MIRT1074831	hsa-miR-27b	CLIP-seq
MIRT2018521	hsa-miR-298	CLIP-seq
MIRT2018522	hsa-miR-3150a-3p	CLIP-seq
MIRT2018523	hsa-miR-3175	CLIP-seq
MIRT2018524	hsa-miR-3187-5p	CLIP-seq
MIRT1074840	hsa-miR-3192	CLIP-seq
MIRT2018525	hsa-miR-339-5p	CLIP-seq
MIRT1074843	hsa-miR-342-5p	CLIP-seq
MIRT2018526	hsa-miR-3591-5p	CLIP-seq
MIRT2018527	hsa-miR-3615	CLIP-seq
MIRT2018528	hsa-miR-3622a-5p	CLIP-seq
MIRT1074850	hsa-miR-375	CLIP-seq
MIRT2018529	hsa-miR-3944-5p	CLIP-seq
MIRT2018530	hsa-miR-4255	CLIP-seq
MIRT2018531	hsa-miR-4269	CLIP-seq
MIRT1074871	hsa-miR-4314	CLIP-seq
MIRT2018532	hsa-miR-4328	CLIP-seq
MIRT2018533	hsa-miR-4436b-3p	CLIP-seq
MIRT2018534	hsa-miR-4446-3p	CLIP-seq
MIRT2018535	hsa-miR-4492	CLIP-seq
MIRT2018536	hsa-miR-4498	CLIP-seq
MIRT2018537	hsa-miR-4505	CLIP-seq
MIRT1074879	hsa-miR-4534	CLIP-seq
MIRT2018538	hsa-miR-4645-5p	CLIP-seq
MIRT1074883	hsa-miR-4646-5p	CLIP-seq
MIRT1074886	hsa-miR-4664-5p	CLIP-seq
MIRT2018539	hsa-miR-4673	CLIP-seq
MIRT2018540	hsa-miR-4685-5p	CLIP-seq
MIRT2018541	hsa-miR-4721	CLIP-seq
MIRT2018542	hsa-miR-4733-3p	CLIP-seq
MIRT1074894	hsa-miR-4755-3p	CLIP-seq
MIRT2018543	hsa-miR-4763-3p	CLIP-seq
MIRT2018544	hsa-miR-4773	CLIP-seq
MIRT1074900	hsa-miR-513a-5p	CLIP-seq
MIRT2018545	hsa-miR-513b	CLIP-seq
MIRT2018546	hsa-miR-515-5p	CLIP-seq
MIRT2018547	hsa-miR-564	CLIP-seq
MIRT2018548	hsa-miR-612	CLIP-seq
MIRT2018549	hsa-miR-762	CLIP-seq
MIRT2018550	hsa-miR-939	CLIP-seq
MIRT1074811	hsa-miR-106a	CLIP-seq
MIRT1074812	hsa-miR-106b	CLIP-seq
MIRT1074813	hsa-miR-1207-3p	CLIP-seq
MIRT2018512	hsa-miR-1207-5p	CLIP-seq
MIRT2250348	hsa-miR-124	CLIP-seq
MIRT2250349	hsa-miR-1247	CLIP-seq
MIRT1074814	hsa-miR-1252	CLIP-seq
MIRT2250350	hsa-miR-1254	CLIP-seq
MIRT1074815	hsa-miR-125a-3p	CLIP-seq
MIRT2250351	hsa-miR-1283	CLIP-seq
MIRT2018513	hsa-miR-1285	CLIP-seq
MIRT2250352	hsa-miR-130a	CLIP-seq
MIRT2250353	hsa-miR-130b	CLIP-seq
MIRT2018515	hsa-miR-132	CLIP-seq
MIRT1074821	hsa-miR-138	CLIP-seq
MIRT2250354	hsa-miR-142-3p	CLIP-seq
MIRT1074824	hsa-miR-153	CLIP-seq
MIRT1074825	hsa-miR-17	CLIP-seq
MIRT2018516	hsa-miR-1909	CLIP-seq
MIRT2018517	hsa-miR-194	CLIP-seq
MIRT2250355	hsa-miR-19a	CLIP-seq
MIRT2250356	hsa-miR-19b	CLIP-seq
MIRT1074826	hsa-miR-20a	CLIP-seq
MIRT1074827	hsa-miR-20b	CLIP-seq
MIRT2018519	hsa-miR-212	CLIP-seq
MIRT2250357	hsa-miR-2467-3p	CLIP-seq
MIRT1074830	hsa-miR-27a	CLIP-seq
MIRT1074831	hsa-miR-27b	CLIP-seq
MIRT2018521	hsa-miR-298	CLIP-seq
MIRT2250358	hsa-miR-301a	CLIP-seq
MIRT2250359	hsa-miR-301b	CLIP-seq
MIRT1074832	hsa-miR-302a	CLIP-seq
MIRT1074833	hsa-miR-302b	CLIP-seq
MIRT1074834	hsa-miR-302c	CLIP-seq
MIRT1074835	hsa-miR-302d	CLIP-seq
MIRT1074836	hsa-miR-302e	CLIP-seq
MIRT2250360	hsa-miR-3116	CLIP-seq
MIRT1074837	hsa-miR-3138	CLIP-seq
MIRT2250361	hsa-miR-3180-5p	CLIP-seq
MIRT2250362	hsa-miR-3183	CLIP-seq
MIRT2250363	hsa-miR-3185	CLIP-seq
MIRT1074839	hsa-miR-3187-3p	CLIP-seq
MIRT2018524	hsa-miR-3187-5p	CLIP-seq
MIRT1074840	hsa-miR-3192	CLIP-seq
MIRT2250364	hsa-miR-324-5p	CLIP-seq
MIRT1074843	hsa-miR-342-5p	CLIP-seq
MIRT1074844	hsa-miR-346	CLIP-seq
MIRT2018526	hsa-miR-3591-5p	CLIP-seq
MIRT1074845	hsa-miR-3609	CLIP-seq
MIRT2250365	hsa-miR-3666	CLIP-seq
MIRT2250366	hsa-miR-3678-3p	CLIP-seq
MIRT1074848	hsa-miR-372	CLIP-seq
MIRT1074849	hsa-miR-373	CLIP-seq
MIRT1074850	hsa-miR-375	CLIP-seq
MIRT2250367	hsa-miR-3909	CLIP-seq
MIRT2250368	hsa-miR-3918	CLIP-seq
MIRT1074862	hsa-miR-3919	CLIP-seq
MIRT1074864	hsa-miR-3934	CLIP-seq
MIRT2250369	hsa-miR-3937	CLIP-seq
MIRT2018529	hsa-miR-3944-5p	CLIP-seq
MIRT1074866	hsa-miR-4254	CLIP-seq
MIRT2018530	hsa-miR-4255	CLIP-seq
MIRT2018531	hsa-miR-4269	CLIP-seq
MIRT2250370	hsa-miR-4279	CLIP-seq
MIRT1074870	hsa-miR-4288	CLIP-seq
MIRT2250371	hsa-miR-4295	CLIP-seq
MIRT2250372	hsa-miR-4297	CLIP-seq
MIRT2250373	hsa-miR-4308	CLIP-seq
MIRT1074871	hsa-miR-4314	CLIP-seq
MIRT2018532	hsa-miR-4328	CLIP-seq
MIRT2250374	hsa-miR-4433	CLIP-seq
MIRT1074872	hsa-miR-4435	CLIP-seq
MIRT2250375	hsa-miR-4459	CLIP-seq
MIRT1074874	hsa-miR-448	CLIP-seq
MIRT2250376	hsa-miR-4486	CLIP-seq
MIRT2018535	hsa-miR-4492	CLIP-seq
MIRT2018536	hsa-miR-4498	CLIP-seq
MIRT2018537	hsa-miR-4505	CLIP-seq
MIRT1074876	hsa-miR-450b-5p	CLIP-seq
MIRT2250377	hsa-miR-4514	CLIP-seq
MIRT2250378	hsa-miR-4519	CLIP-seq
MIRT1074877	hsa-miR-4520a-3p	CLIP-seq
MIRT1074879	hsa-miR-4534	CLIP-seq
MIRT2250379	hsa-miR-454	CLIP-seq
MIRT1074880	hsa-miR-455-3p	CLIP-seq
MIRT2250380	hsa-miR-4640-5p	CLIP-seq
MIRT2250381	hsa-miR-4642	CLIP-seq
MIRT1074881	hsa-miR-4643	CLIP-seq
MIRT1074883	hsa-miR-4646-5p	CLIP-seq
MIRT1074884	hsa-miR-4651	CLIP-seq
MIRT1074885	hsa-miR-466	CLIP-seq
MIRT1074886	hsa-miR-4664-5p	CLIP-seq
MIRT2250382	hsa-miR-4671-3p	CLIP-seq
MIRT2018540	hsa-miR-4685-5p	CLIP-seq
MIRT2250383	hsa-miR-4692	CLIP-seq
MIRT1074889	hsa-miR-4701-5p	CLIP-seq
MIRT2250384	hsa-miR-4704-3p	CLIP-seq
MIRT2250385	hsa-miR-4709-3p	CLIP-seq
MIRT1074891	hsa-miR-4717-3p	CLIP-seq
MIRT2250386	hsa-miR-4720-5p	CLIP-seq
MIRT2250387	hsa-miR-4722-3p	CLIP-seq
MIRT2250388	hsa-miR-4723-3p	CLIP-seq
MIRT2250389	hsa-miR-4726-5p	CLIP-seq
MIRT2018542	hsa-miR-4733-3p	CLIP-seq
MIRT2250390	hsa-miR-4753-3p	CLIP-seq
MIRT1074894	hsa-miR-4755-3p	CLIP-seq
MIRT2250391	hsa-miR-4761-3p	CLIP-seq
MIRT2018543	hsa-miR-4763-3p	CLIP-seq
MIRT2250392	hsa-miR-4763-5p	CLIP-seq
MIRT2250393	hsa-miR-4768-3p	CLIP-seq
MIRT2018544	hsa-miR-4773	CLIP-seq
MIRT2250394	hsa-miR-4779	CLIP-seq
MIRT1074896	hsa-miR-4789-3p	CLIP-seq
MIRT1074897	hsa-miR-4789-5p	CLIP-seq
MIRT1074898	hsa-miR-4796-3p	CLIP-seq
MIRT2250395	hsa-miR-4799-3p	CLIP-seq
MIRT2250396	hsa-miR-506	CLIP-seq
MIRT2250397	hsa-miR-5095	CLIP-seq
MIRT2250398	hsa-miR-512-3p	CLIP-seq
MIRT1074900	hsa-miR-513a-5p	CLIP-seq
MIRT2250399	hsa-miR-514	CLIP-seq
MIRT2250400	hsa-miR-514b-3p	CLIP-seq
MIRT2018546	hsa-miR-515-5p	CLIP-seq
MIRT1074901	hsa-miR-518a-5p	CLIP-seq
MIRT1074902	hsa-miR-519d	CLIP-seq
MIRT1074903	hsa-miR-520a-3p	CLIP-seq
MIRT2250401	hsa-miR-520a-5p	CLIP-seq
MIRT1074904	hsa-miR-520b	CLIP-seq
MIRT1074905	hsa-miR-520c-3p	CLIP-seq
MIRT1074906	hsa-miR-520d-3p	CLIP-seq
MIRT1074907	hsa-miR-520e	CLIP-seq
MIRT2250402	hsa-miR-525-5p	CLIP-seq
MIRT1074909	hsa-miR-527	CLIP-seq
MIRT1074911	hsa-miR-548ah	CLIP-seq
MIRT1074912	hsa-miR-548an	CLIP-seq
MIRT1074914	hsa-miR-548s	CLIP-seq
MIRT1074916	hsa-miR-588	CLIP-seq
MIRT2250403	hsa-miR-600	CLIP-seq
MIRT1074917	hsa-miR-608	CLIP-seq
MIRT2018548	hsa-miR-612	CLIP-seq
MIRT2250404	hsa-miR-615-5p	CLIP-seq
MIRT1074918	hsa-miR-632	CLIP-seq
MIRT2250405	hsa-miR-661	CLIP-seq
MIRT2018549	hsa-miR-762	CLIP-seq
MIRT1074921	hsa-miR-764	CLIP-seq
MIRT1074924	hsa-miR-93	CLIP-seq
MIRT2250357	hsa-miR-2467-3p	CLIP-seq
MIRT2250366	hsa-miR-3678-3p	CLIP-seq
MIRT2250405	hsa-miR-661	CLIP-seq
MIRT2452023	hsa-miR-3591-3p	CLIP-seq
MIRT2452024	hsa-miR-4670-3p	CLIP-seq
MIRT2018514	hsa-miR-1289	CLIP-seq
MIRT2018518	hsa-miR-2114	CLIP-seq
MIRT2018525	hsa-miR-339-5p	CLIP-seq
MIRT1074894	hsa-miR-4755-3p	CLIP-seq
MIRT2553987	hsa-miR-711	CLIP-seq
MIRT2018513	hsa-miR-1285	CLIP-seq
MIRT2018514	hsa-miR-1289	CLIP-seq
MIRT2018518	hsa-miR-2114	CLIP-seq
MIRT2683015	hsa-miR-3117-5p	CLIP-seq
MIRT2683016	hsa-miR-3153	CLIP-seq
MIRT2250363	hsa-miR-3185	CLIP-seq
MIRT2018524	hsa-miR-3187-5p	CLIP-seq
MIRT2018525	hsa-miR-339-5p	CLIP-seq
MIRT2018528	hsa-miR-3622a-5p	CLIP-seq
MIRT2018531	hsa-miR-4269	CLIP-seq
MIRT2018534	hsa-miR-4446-3p	CLIP-seq
MIRT2683017	hsa-miR-4484	CLIP-seq
MIRT2018535	hsa-miR-4492	CLIP-seq
MIRT2018536	hsa-miR-4498	CLIP-seq
MIRT2018537	hsa-miR-4505	CLIP-seq
MIRT2683018	hsa-miR-4509	CLIP-seq
MIRT1074883	hsa-miR-4646-5p	CLIP-seq
MIRT2683019	hsa-miR-4668-5p	CLIP-seq
MIRT2250385	hsa-miR-4709-3p	CLIP-seq
MIRT2018541	hsa-miR-4721	CLIP-seq
MIRT1074894	hsa-miR-4755-3p	CLIP-seq
MIRT1074912	hsa-miR-548an	CLIP-seq
MIRT2018547	hsa-miR-564	CLIP-seq
MIRT2018548	hsa-miR-612	CLIP-seq
MIRT2250405	hsa-miR-661	CLIP-seq
MIRT2553987	hsa-miR-711	CLIP-seq
MIRT2018549	hsa-miR-762	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	IEA
GO:0000166	Function	Nucleotide binding	IEA
GO:0000828	Function	Inositol hexakisphosphate kinase activity	IBA
GO:0002262	Process	Myeloid cell homeostasis	IEA
GO:0005515	Function	Protein binding	IPI	21516116, 23060452, 25416956, 32296183, 35512704
GO:0005516	Function	Calmodulin binding	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	12747803
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA	12747803
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IDA	12747803
GO:0005856	Component	Cytoskeleton	IEA
GO:0007165	Process	Signal transduction	TAS	1654894
GO:0007166	Process	Cell surface receptor signaling pathway	IEA
GO:0008440	Function	Inositol-1,4,5-trisphosphate 3-kinase activity	IDA	1654894, 12747803
GO:0008440	Function	Inositol-1,4,5-trisphosphate 3-kinase activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030217	Process	T cell differentiation	IEA
GO:0032957	Process	Inositol trisphosphate metabolic process	IDA	1654894
GO:0032958	Process	Inositol phosphate biosynthetic process	IBA
GO:0032958	Process	Inositol phosphate biosynthetic process	IEA
GO:0033030	Process	Negative regulation of neutrophil apoptotic process	IEA
GO:0035726	Process	Common myeloid progenitor cell proliferation	IEA
GO:0045059	Process	Positive thymic T cell selection	IEA
GO:0045061	Process	Thymic T cell selection	IEA
GO:0045638	Process	Negative regulation of myeloid cell differentiation	IEA
GO:0046579	Process	Positive regulation of Ras protein signal transduction	IEA
GO:0046638	Process	Positive regulation of alpha-beta T cell differentiation	IEA
GO:0046854	Process	Phosphatidylinositol phosphate biosynthetic process	IBA
GO:0046854	Process	Phosphatidylinositol phosphate biosynthetic process	IDA	12747803
GO:0046854	Process	Phosphatidylinositol phosphate biosynthetic process	IEA
GO:0071277	Process	Cellular response to calcium ion	IDA	1654894, 12747803
GO:0071277	Process	Cellular response to calcium ion	IEA

Other IDs

• MIM: 147522
• HGNC: 6179
• e!Ensembl: ENSG00000143772

Protein

• UniProt ID: P27987
• Protein name: Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B)
• Protein function: Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. {ECO:0000269|PubMed:11846419, ECO:0000269|PubMed:12747803, ECO
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03770	IPK	726 → 937	Inositol polyphosphate kinase	Family

• Sequence:

  MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
  AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS
  PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
  RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
  AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
  TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
  GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS
  VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
  CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
  ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
  SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
  VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
  KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA
  PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF
  REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK
  TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA

• Sequence length: 946

Pathways

KEGG:

Inositol phosphate metabolism
Metabolic pathways
Calcium signaling pathway
Phosphatidylinositol signaling system

Reactome:

Synthesis of IP3 and IP4 in the cytosol

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ASTHMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLONIC NEOPLASM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DENTAL CARIES	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GILLES DE LA TOURETTE SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPEROPIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ITPKB-related disorder	Benign; Uncertain significance; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Myeloproliferative neoplasm, unclassifiable	Conflicting classifications of pathogenicity; Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARKINSON DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RESPIRATORY SYSTEM DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
URTICARIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Autism Spectrum Disorder	Autism	Pubtator	37407249	Associate	★☆☆☆☆ Found in Text Mining only
B-Cell Lymphomas	B-Cell Lymphoma	BEFREE	30638402		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	29871874		★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	34598322	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Small Cell	Small cell carcinoma	Pubtator	26642205	Associate	★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	35937947	Associate	★☆☆☆☆ Found in Text Mining only
Hodgkin Disease	Hodgkin disease	Pubtator	29650799, 31822802, 32079702	Associate	★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	26384344		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus Systemic	Systemic lupus erythematosus	Pubtator	34084162	Associate	★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	36306325	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	29871874		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31081803		★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	16946712	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29871874, 31081803		★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	GWASCAT_DG	28892059		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Parkinson Disease	Parkinson disease	BEFREE	30814023		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Parkinson Disease	Parkinson disease	Pubtator	36768321	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Respiratory Tract Diseases	Respiratory Tract Diseases	GWASCAT_DG	30595370		★☆☆☆☆ Found in Text Mining only