IGL (immunoglobulin lambda locus)

Gene Gene information from NCBI Gene database.
Gene Other IDs Associated diseases
Entrez ID 3535
Gene name Immunoglobulin lambda locus
Gene symbol IGL
Synonyms (NCBI Gene)
IGL@IGLC6
Chromosome 22
Chromosome location 22q11.22
Summary Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light cha
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Other IDs Associated diseases
MIM HGNC e!Ensembl
HGNC 5853 N/A
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Gene Other IDs Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
OMPHALOCELE EXSTROPHY IMPERFORATE ANUS — Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (3)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Burkitt Lymphoma Burkitt`s Lymphoma BEFREE 6467987
★★★★★
★☆☆☆☆
Found in Text Mining only
Cat eye syndrome Cat Eye Syndrome BEFREE 7759132
★★★★★
★☆☆☆☆
Found in Text Mining only
DiGeorge Syndrome DiGeorge Syndrome BEFREE 3930157
★★★★★
★☆☆☆☆
Found in Text Mining only