ANKDD1A (ankyrin repeat and death domain containing 1A)

Gene

• Entrez ID: 348094
• Gene name: Ankyrin repeat and death domain containing 1A
• Gene symbol: ANKDD1A
• Synonyms (NCBI Gene): -
• Chromosome: 15
• Chromosome location: 15q22.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT781757	hsa-miR-186	CLIP-seq
MIRT781758	hsa-miR-34b	CLIP-seq
MIRT781759	hsa-miR-3690	CLIP-seq
MIRT781760	hsa-miR-4254	CLIP-seq
MIRT781761	hsa-miR-4420	CLIP-seq
MIRT781762	hsa-miR-4433	CLIP-seq
MIRT781763	hsa-miR-4459	CLIP-seq
MIRT781764	hsa-miR-4693-5p	CLIP-seq
MIRT781765	hsa-miR-4768-3p	CLIP-seq
MIRT781766	hsa-miR-491-3p	CLIP-seq
MIRT781767	hsa-miR-548c-3p	CLIP-seq
MIRT781768	hsa-miR-875-3p	CLIP-seq
MIRT2171330	hsa-miR-2278	CLIP-seq
MIRT781761	hsa-miR-4420	CLIP-seq
MIRT2171331	hsa-miR-4786-3p	CLIP-seq
MIRT2171332	hsa-miR-671-5p	CLIP-seq
MIRT2171330	hsa-miR-2278	CLIP-seq
MIRT2474315	hsa-miR-23a	CLIP-seq
MIRT2474316	hsa-miR-23b	CLIP-seq
MIRT2474317	hsa-miR-23c	CLIP-seq
MIRT2474318	hsa-miR-3129-3p	CLIP-seq
MIRT2474319	hsa-miR-3675-3p	CLIP-seq
MIRT2474320	hsa-miR-4462	CLIP-seq
MIRT2474321	hsa-miR-4662a-5p	CLIP-seq
MIRT2474322	hsa-miR-4676-5p	CLIP-seq
MIRT2474323	hsa-miR-4684-5p	CLIP-seq
MIRT781767	hsa-miR-548c-3p	CLIP-seq
MIRT2474324	hsa-miR-575	CLIP-seq
MIRT2474318	hsa-miR-3129-3p	CLIP-seq
MIRT2474320	hsa-miR-4462	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	33961781
GO:0007165	Process	Signal transduction	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q495B1
• Protein name: Ankyrin repeat and death domain-containing protein 1A
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	19 → 121	Ankyrin repeats (3 copies)	Repeat
  PF13637	Ank_4	159 → 212		Repeat
  PF12796	Ank_2	248 → 321	Ankyrin repeats (3 copies)	Repeat
  PF13857	Ank_5	312 → 364		Repeat

• Sequence:

  MQEELAWETDGLLPLERQLHEAARQNNVGRMQELIGRRVNTRARNHVGRVALHWAAGAGH
  EQAVRLLLEHEAAVDEEDAVGALTEARLCFGMNALLLSAWFGHLRILQILVNSGAKIHCE
  SKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVG
  SGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDC
  VQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVR
  HNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTA
  LAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKSLSFKQDHRQETQQLRSVLWRLAS
  RYLQPREWKKLAYSWEFTEAHVDAIEQQWTGTRSYQEHGHRMLLIWLHGVATAGENPSKA
  LFEGLVAIGRRDLAGWSTMARSQLTATSASRVQMILVPQPPE

• Sequence length: 522

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Glioblastoma	Glioblastoma	BEFREE	30082910		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	30082910	Inhibit	★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	30082910		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	21962230	Inhibit	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	30651372	Associate	★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	30082910	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30082910		★☆☆☆☆ Found in Text Mining only