ZNF81 (zinc finger protein 81)

Gene

• Entrez ID: 347344
• Gene name: Zinc finger protein 81
• Gene symbol: ZNF81
• Synonyms (NCBI Gene): HFZ20, MRX45, dJ54B20.6
• Chromosome: X
• Chromosome location: Xp11.23
• Summary: This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microdu

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs41312157	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity, benign	Coding sequence variant, intron variant, missense variant, genic downstream transcript variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT029112	hsa-miR-26b-5p	Microarray	19088304
MIRT529662	hsa-miR-548ae-3p	PAR-CLIP	22012620
MIRT529661	hsa-miR-548ah-3p	PAR-CLIP	22012620
MIRT529660	hsa-miR-548aj-3p	PAR-CLIP	22012620
MIRT529659	hsa-miR-548am-3p	PAR-CLIP	22012620
MIRT529658	hsa-miR-548aq-3p	PAR-CLIP	22012620
MIRT529657	hsa-miR-548j-3p	PAR-CLIP	22012620
MIRT529656	hsa-miR-548x-3p	PAR-CLIP	22012620
MIRT529655	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT529654	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT529653	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT529652	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT529651	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT529650	hsa-miR-4649-3p	PAR-CLIP	22012620
MIRT529649	hsa-miR-3975	PAR-CLIP	22012620
MIRT529648	hsa-miR-2467-5p	PAR-CLIP	22012620
MIRT529647	hsa-miR-485-5p	PAR-CLIP	22012620
MIRT529646	hsa-miR-6884-5p	PAR-CLIP	22012620
MIRT529645	hsa-miR-3188	PAR-CLIP	22012620
MIRT529644	hsa-miR-3136-3p	PAR-CLIP	22012620
MIRT529643	hsa-miR-7155-3p	PAR-CLIP	22012620
MIRT529662	hsa-miR-548ae-3p	PAR-CLIP	22012620
MIRT529661	hsa-miR-548ah-3p	PAR-CLIP	22012620
MIRT529660	hsa-miR-548aj-3p	PAR-CLIP	22012620
MIRT529659	hsa-miR-548am-3p	PAR-CLIP	22012620
MIRT529658	hsa-miR-548aq-3p	PAR-CLIP	22012620
MIRT529657	hsa-miR-548j-3p	PAR-CLIP	22012620
MIRT529656	hsa-miR-548x-3p	PAR-CLIP	22012620
MIRT529655	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT529654	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT529653	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT529652	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT529651	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT529650	hsa-miR-4649-3p	PAR-CLIP	22012620
MIRT529649	hsa-miR-3975	PAR-CLIP	22012620
MIRT529648	hsa-miR-2467-5p	PAR-CLIP	22012620
MIRT529647	hsa-miR-485-5p	PAR-CLIP	22012620
MIRT529646	hsa-miR-6884-5p	PAR-CLIP	22012620
MIRT529645	hsa-miR-3188	PAR-CLIP	22012620
MIRT529644	hsa-miR-3136-3p	PAR-CLIP	22012620
MIRT529643	hsa-miR-7155-3p	PAR-CLIP	22012620
MIRT1540750	hsa-let-7a	CLIP-seq
MIRT1540751	hsa-let-7b	CLIP-seq
MIRT1540752	hsa-let-7c	CLIP-seq
MIRT1540753	hsa-let-7d	CLIP-seq
MIRT1540754	hsa-let-7e	CLIP-seq
MIRT1540755	hsa-let-7f	CLIP-seq
MIRT1540756	hsa-let-7g	CLIP-seq
MIRT1540757	hsa-let-7i	CLIP-seq
MIRT1540758	hsa-miR-103a	CLIP-seq
MIRT1540759	hsa-miR-107	CLIP-seq
MIRT1540760	hsa-miR-1197	CLIP-seq
MIRT1540761	hsa-miR-1207-3p	CLIP-seq
MIRT1540762	hsa-miR-1255a	CLIP-seq
MIRT1540763	hsa-miR-1255b	CLIP-seq
MIRT1540764	hsa-miR-1282	CLIP-seq
MIRT1540765	hsa-miR-1285	CLIP-seq
MIRT1540766	hsa-miR-133a	CLIP-seq
MIRT1540767	hsa-miR-133b	CLIP-seq
MIRT1540768	hsa-miR-134	CLIP-seq
MIRT1540769	hsa-miR-135a	CLIP-seq
MIRT1540770	hsa-miR-135b	CLIP-seq
MIRT1540771	hsa-miR-149	CLIP-seq
MIRT1540772	hsa-miR-15a	CLIP-seq
MIRT1540773	hsa-miR-15b	CLIP-seq
MIRT1540774	hsa-miR-16	CLIP-seq
MIRT1540775	hsa-miR-181a	CLIP-seq
MIRT1540776	hsa-miR-181b	CLIP-seq
MIRT1540777	hsa-miR-181c	CLIP-seq
MIRT1540778	hsa-miR-181d	CLIP-seq
MIRT1540779	hsa-miR-1910	CLIP-seq
MIRT1540780	hsa-miR-195	CLIP-seq
MIRT1540781	hsa-miR-196a	CLIP-seq
MIRT1540782	hsa-miR-196b	CLIP-seq
MIRT1540783	hsa-miR-205	CLIP-seq
MIRT1540784	hsa-miR-2110	CLIP-seq
MIRT1540785	hsa-miR-2114	CLIP-seq
MIRT1540786	hsa-miR-214	CLIP-seq
MIRT1540787	hsa-miR-2278	CLIP-seq
MIRT1540788	hsa-miR-24	CLIP-seq
MIRT1540789	hsa-miR-302f	CLIP-seq
MIRT1540790	hsa-miR-3118	CLIP-seq
MIRT1540791	hsa-miR-3120-5p	CLIP-seq
MIRT1540792	hsa-miR-3126-5p	CLIP-seq
MIRT1540793	hsa-miR-3127-5p	CLIP-seq
MIRT1540794	hsa-miR-3148	CLIP-seq
MIRT1540795	hsa-miR-3153	CLIP-seq
MIRT1540796	hsa-miR-3157-5p	CLIP-seq
MIRT1540797	hsa-miR-3164	CLIP-seq
MIRT1540798	hsa-miR-3171	CLIP-seq
MIRT1540799	hsa-miR-3182	CLIP-seq
MIRT1540800	hsa-miR-3185	CLIP-seq
MIRT1540801	hsa-miR-3187-5p	CLIP-seq
MIRT1540802	hsa-miR-3200-5p	CLIP-seq
MIRT1540803	hsa-miR-324-5p	CLIP-seq
MIRT1540804	hsa-miR-34c-3p	CLIP-seq
MIRT1540805	hsa-miR-3545-3p	CLIP-seq
MIRT1540806	hsa-miR-3617	CLIP-seq
MIRT1540807	hsa-miR-3619-5p	CLIP-seq
MIRT1540808	hsa-miR-3646	CLIP-seq
MIRT1540809	hsa-miR-3647-3p	CLIP-seq
MIRT1540810	hsa-miR-3676	CLIP-seq
MIRT1540811	hsa-miR-3679-3p	CLIP-seq
MIRT1540812	hsa-miR-3688-3p	CLIP-seq
MIRT1540813	hsa-miR-3689d	CLIP-seq
MIRT1540814	hsa-miR-378g	CLIP-seq
MIRT1540815	hsa-miR-3923	CLIP-seq
MIRT1540816	hsa-miR-3929	CLIP-seq
MIRT1540817	hsa-miR-3944-5p	CLIP-seq
MIRT1540818	hsa-miR-410	CLIP-seq
MIRT1540819	hsa-miR-424	CLIP-seq
MIRT1540820	hsa-miR-4254	CLIP-seq
MIRT1540821	hsa-miR-4262	CLIP-seq
MIRT1540822	hsa-miR-4271	CLIP-seq
MIRT1540823	hsa-miR-4283	CLIP-seq
MIRT1540824	hsa-miR-4284	CLIP-seq
MIRT1540825	hsa-miR-4291	CLIP-seq
MIRT1540826	hsa-miR-4292	CLIP-seq
MIRT1540827	hsa-miR-4308	CLIP-seq
MIRT1540828	hsa-miR-431	CLIP-seq
MIRT1540829	hsa-miR-4314	CLIP-seq
MIRT1540830	hsa-miR-432	CLIP-seq
MIRT1540831	hsa-miR-433	CLIP-seq
MIRT1540832	hsa-miR-4419a	CLIP-seq
MIRT1540833	hsa-miR-4419b	CLIP-seq
MIRT1540834	hsa-miR-4426	CLIP-seq
MIRT1540835	hsa-miR-4438	CLIP-seq
MIRT1540836	hsa-miR-4450	CLIP-seq
MIRT1540837	hsa-miR-4458	CLIP-seq
MIRT1540838	hsa-miR-4459	CLIP-seq
MIRT1540839	hsa-miR-4468	CLIP-seq
MIRT1540840	hsa-miR-4478	CLIP-seq
MIRT1540841	hsa-miR-4484	CLIP-seq
MIRT1540842	hsa-miR-4486	CLIP-seq
MIRT1540843	hsa-miR-4489	CLIP-seq
MIRT1540844	hsa-miR-4500	CLIP-seq
MIRT1540845	hsa-miR-4504	CLIP-seq
MIRT1540846	hsa-miR-4509	CLIP-seq
MIRT1540847	hsa-miR-4510	CLIP-seq
MIRT1540848	hsa-miR-452	CLIP-seq
MIRT1540849	hsa-miR-4524	CLIP-seq
MIRT1540850	hsa-miR-455-3p	CLIP-seq
MIRT1540851	hsa-miR-4647	CLIP-seq
MIRT1540852	hsa-miR-4650-5p	CLIP-seq
MIRT1540853	hsa-miR-4661-3p	CLIP-seq
MIRT1540854	hsa-miR-4662a-5p	CLIP-seq
MIRT1540855	hsa-miR-4662b	CLIP-seq
MIRT1540856	hsa-miR-4666-5p	CLIP-seq
MIRT1540857	hsa-miR-4668-5p	CLIP-seq
MIRT1540858	hsa-miR-4676-3p	CLIP-seq
MIRT1540859	hsa-miR-4676-5p	CLIP-seq
MIRT1540860	hsa-miR-4677-3p	CLIP-seq
MIRT1540861	hsa-miR-4679	CLIP-seq
MIRT1540862	hsa-miR-4682	CLIP-seq
MIRT1540863	hsa-miR-4691-3p	CLIP-seq
MIRT1540864	hsa-miR-4694-3p	CLIP-seq
MIRT1540865	hsa-miR-4696	CLIP-seq
MIRT1540866	hsa-miR-4720-3p	CLIP-seq
MIRT1540867	hsa-miR-4725-3p	CLIP-seq
MIRT1540868	hsa-miR-4731-5p	CLIP-seq
MIRT1540869	hsa-miR-4756-3p	CLIP-seq
MIRT1540870	hsa-miR-4760-3p	CLIP-seq
MIRT1540871	hsa-miR-4762-5p	CLIP-seq
MIRT1540872	hsa-miR-4774-5p	CLIP-seq
MIRT1540873	hsa-miR-4778-5p	CLIP-seq
MIRT1540874	hsa-miR-4789-3p	CLIP-seq
MIRT1540875	hsa-miR-4804-3p	CLIP-seq
MIRT1540876	hsa-miR-490-3p	CLIP-seq
MIRT1540877	hsa-miR-491-5p	CLIP-seq
MIRT1540878	hsa-miR-497	CLIP-seq
MIRT1540879	hsa-miR-503	CLIP-seq
MIRT1540880	hsa-miR-5095	CLIP-seq
MIRT1540881	hsa-miR-519a	CLIP-seq
MIRT1540882	hsa-miR-519b-3p	CLIP-seq
MIRT1540883	hsa-miR-519c-3p	CLIP-seq
MIRT1540884	hsa-miR-542-3p	CLIP-seq
MIRT1540885	hsa-miR-545	CLIP-seq
MIRT1540886	hsa-miR-548an	CLIP-seq
MIRT1540887	hsa-miR-570	CLIP-seq
MIRT1540888	hsa-miR-575	CLIP-seq
MIRT1540889	hsa-miR-579	CLIP-seq
MIRT1540890	hsa-miR-582-3p	CLIP-seq
MIRT1540891	hsa-miR-587	CLIP-seq
MIRT1540892	hsa-miR-595	CLIP-seq
MIRT1540893	hsa-miR-610	CLIP-seq
MIRT1540894	hsa-miR-612	CLIP-seq
MIRT1540895	hsa-miR-619	CLIP-seq
MIRT1540896	hsa-miR-641	CLIP-seq
MIRT1540897	hsa-miR-642b	CLIP-seq
MIRT1540898	hsa-miR-645	CLIP-seq
MIRT1540899	hsa-miR-646	CLIP-seq
MIRT1540900	hsa-miR-657	CLIP-seq
MIRT1540901	hsa-miR-665	CLIP-seq
MIRT1540902	hsa-miR-760	CLIP-seq
MIRT1540903	hsa-miR-761	CLIP-seq
MIRT1540904	hsa-miR-889	CLIP-seq
MIRT1540905	hsa-miR-922	CLIP-seq
MIRT1540906	hsa-miR-938	CLIP-seq
MIRT1540907	hsa-miR-98	CLIP-seq
MIRT1540760	hsa-miR-1197	CLIP-seq
MIRT2163275	hsa-miR-129-5p	CLIP-seq
MIRT2163276	hsa-miR-141	CLIP-seq
MIRT2163277	hsa-miR-188-3p	CLIP-seq
MIRT2163278	hsa-miR-200a	CLIP-seq
MIRT1540784	hsa-miR-2110	CLIP-seq
MIRT1540786	hsa-miR-214	CLIP-seq
MIRT2163279	hsa-miR-224	CLIP-seq
MIRT2163280	hsa-miR-2681	CLIP-seq
MIRT2163281	hsa-miR-3065-5p	CLIP-seq
MIRT2163282	hsa-miR-3119	CLIP-seq
MIRT2163283	hsa-miR-3128	CLIP-seq
MIRT2163284	hsa-miR-3138	CLIP-seq
MIRT2163285	hsa-miR-3155	CLIP-seq
MIRT2163286	hsa-miR-3155b	CLIP-seq
MIRT2163287	hsa-miR-3157-3p	CLIP-seq
MIRT1540799	hsa-miR-3182	CLIP-seq
MIRT2163288	hsa-miR-3607-5p	CLIP-seq
MIRT1540807	hsa-miR-3619-5p	CLIP-seq
MIRT2163289	hsa-miR-3663-3p	CLIP-seq
MIRT2163290	hsa-miR-3664-3p	CLIP-seq
MIRT2163291	hsa-miR-3688-5p	CLIP-seq
MIRT2163292	hsa-miR-3692	CLIP-seq
MIRT2163293	hsa-miR-369-3p	CLIP-seq
MIRT2163294	hsa-miR-3713	CLIP-seq
MIRT2163295	hsa-miR-374a	CLIP-seq
MIRT2163296	hsa-miR-374b	CLIP-seq
MIRT2163297	hsa-miR-3940-5p	CLIP-seq
MIRT1540822	hsa-miR-4271	CLIP-seq
MIRT2163298	hsa-miR-4290	CLIP-seq
MIRT1540825	hsa-miR-4291	CLIP-seq
MIRT2163299	hsa-miR-4327	CLIP-seq
MIRT2163300	hsa-miR-4330	CLIP-seq
MIRT1540834	hsa-miR-4426	CLIP-seq
MIRT2163301	hsa-miR-4427	CLIP-seq
MIRT2163302	hsa-miR-4436a	CLIP-seq
MIRT2163303	hsa-miR-4491	CLIP-seq
MIRT2163304	hsa-miR-4494	CLIP-seq
MIRT2163305	hsa-miR-4507	CLIP-seq
MIRT2163306	hsa-miR-4535	CLIP-seq
MIRT2163307	hsa-miR-4640-5p	CLIP-seq
MIRT2163308	hsa-miR-4642	CLIP-seq
MIRT2163309	hsa-miR-4645-5p	CLIP-seq
MIRT1540851	hsa-miR-4647	CLIP-seq
MIRT2163310	hsa-miR-4652-3p	CLIP-seq
MIRT2163311	hsa-miR-4657	CLIP-seq
MIRT1540855	hsa-miR-4662b	CLIP-seq
MIRT2163312	hsa-miR-4673	CLIP-seq
MIRT2163313	hsa-miR-4695-3p	CLIP-seq
MIRT1540867	hsa-miR-4725-3p	CLIP-seq
MIRT2163314	hsa-miR-4726-5p	CLIP-seq
MIRT1540868	hsa-miR-4731-5p	CLIP-seq
MIRT2163315	hsa-miR-4762-3p	CLIP-seq
MIRT2163316	hsa-miR-4800-5p	CLIP-seq
MIRT2163317	hsa-miR-484	CLIP-seq
MIRT2163318	hsa-miR-492	CLIP-seq
MIRT2163319	hsa-miR-499a-5p	CLIP-seq
MIRT2163320	hsa-miR-513a-3p	CLIP-seq
MIRT2163321	hsa-miR-513c	CLIP-seq
MIRT2163322	hsa-miR-514b-5p	CLIP-seq
MIRT2163323	hsa-miR-548ag	CLIP-seq
MIRT2163324	hsa-miR-548ai	CLIP-seq
MIRT2163325	hsa-miR-548e	CLIP-seq
MIRT2163326	hsa-miR-548f	CLIP-seq
MIRT2163327	hsa-miR-548m	CLIP-seq
MIRT2163328	hsa-miR-556-5p	CLIP-seq
MIRT2163329	hsa-miR-617	CLIP-seq
MIRT2163330	hsa-miR-643	CLIP-seq
MIRT2163331	hsa-miR-664	CLIP-seq
MIRT1540901	hsa-miR-665	CLIP-seq
MIRT1540903	hsa-miR-761	CLIP-seq
MIRT2163332	hsa-miR-874	CLIP-seq
MIRT1540905	hsa-miR-922	CLIP-seq
MIRT2163333	hsa-miR-943	CLIP-seq
MIRT2382397	hsa-miR-1202	CLIP-seq
MIRT2382398	hsa-miR-1208	CLIP-seq
MIRT2382399	hsa-miR-125a-3p	CLIP-seq
MIRT2382400	hsa-miR-1264	CLIP-seq
MIRT2382401	hsa-miR-1321	CLIP-seq
MIRT2382402	hsa-miR-145	CLIP-seq
MIRT2382403	hsa-miR-185	CLIP-seq
MIRT1540786	hsa-miR-214	CLIP-seq
MIRT2163279	hsa-miR-224	CLIP-seq
MIRT2163282	hsa-miR-3119	CLIP-seq
MIRT1540793	hsa-miR-3127-5p	CLIP-seq
MIRT2163285	hsa-miR-3155	CLIP-seq
MIRT2163286	hsa-miR-3155b	CLIP-seq
MIRT2382404	hsa-miR-3162-5p	CLIP-seq
MIRT1540799	hsa-miR-3182	CLIP-seq
MIRT2382405	hsa-miR-3194-5p	CLIP-seq
MIRT2382406	hsa-miR-320a	CLIP-seq
MIRT2382407	hsa-miR-320b	CLIP-seq
MIRT2382408	hsa-miR-320c	CLIP-seq
MIRT2382409	hsa-miR-320d	CLIP-seq
MIRT2382410	hsa-miR-320e	CLIP-seq
MIRT1540807	hsa-miR-3619-5p	CLIP-seq
MIRT2382411	hsa-miR-3686	CLIP-seq
MIRT2163291	hsa-miR-3688-5p	CLIP-seq
MIRT1540813	hsa-miR-3689d	CLIP-seq
MIRT2382412	hsa-miR-3691-3p	CLIP-seq
MIRT2163293	hsa-miR-369-3p	CLIP-seq
MIRT2382413	hsa-miR-376c	CLIP-seq
MIRT2382414	hsa-miR-3919	CLIP-seq
MIRT2382415	hsa-miR-3934	CLIP-seq
MIRT2382416	hsa-miR-3972	CLIP-seq
MIRT1540825	hsa-miR-4291	CLIP-seq
MIRT1540826	hsa-miR-4292	CLIP-seq
MIRT2382417	hsa-miR-4306	CLIP-seq
MIRT1540827	hsa-miR-4308	CLIP-seq
MIRT2382418	hsa-miR-4313	CLIP-seq
MIRT2382419	hsa-miR-4320	CLIP-seq
MIRT2382420	hsa-miR-4328	CLIP-seq
MIRT2163300	hsa-miR-4330	CLIP-seq
MIRT2382421	hsa-miR-4429	CLIP-seq
MIRT2382422	hsa-miR-4436b-3p	CLIP-seq
MIRT1540836	hsa-miR-4450	CLIP-seq
MIRT2382423	hsa-miR-4474-3p	CLIP-seq
MIRT2163304	hsa-miR-4494	CLIP-seq
MIRT1540850	hsa-miR-455-3p	CLIP-seq
MIRT2382424	hsa-miR-4635	CLIP-seq
MIRT2382425	hsa-miR-4644	CLIP-seq
MIRT2163309	hsa-miR-4645-5p	CLIP-seq
MIRT2382426	hsa-miR-4670-3p	CLIP-seq
MIRT2163312	hsa-miR-4673	CLIP-seq
MIRT1540860	hsa-miR-4677-3p	CLIP-seq
MIRT1540864	hsa-miR-4694-3p	CLIP-seq
MIRT2163313	hsa-miR-4695-3p	CLIP-seq
MIRT2382427	hsa-miR-4698	CLIP-seq
MIRT2382428	hsa-miR-4717-5p	CLIP-seq
MIRT2382429	hsa-miR-4727-5p	CLIP-seq
MIRT2382430	hsa-miR-4728-5p	CLIP-seq
MIRT2382431	hsa-miR-4739	CLIP-seq
MIRT2382432	hsa-miR-4742-3p	CLIP-seq
MIRT1540869	hsa-miR-4756-3p	CLIP-seq
MIRT2382433	hsa-miR-4756-5p	CLIP-seq
MIRT2382434	hsa-miR-4766-5p	CLIP-seq
MIRT2382435	hsa-miR-4779	CLIP-seq
MIRT2382436	hsa-miR-4786-3p	CLIP-seq
MIRT2382437	hsa-miR-4797-5p	CLIP-seq
MIRT2382438	hsa-miR-4802-3p	CLIP-seq
MIRT2163317	hsa-miR-484	CLIP-seq
MIRT1540877	hsa-miR-491-5p	CLIP-seq
MIRT2163319	hsa-miR-499a-5p	CLIP-seq
MIRT2163320	hsa-miR-513a-3p	CLIP-seq
MIRT2163321	hsa-miR-513c	CLIP-seq
MIRT2163322	hsa-miR-514b-5p	CLIP-seq
MIRT2382439	hsa-miR-520a-5p	CLIP-seq
MIRT2382440	hsa-miR-525-5p	CLIP-seq
MIRT2382441	hsa-miR-526b	CLIP-seq
MIRT2382442	hsa-miR-544	CLIP-seq
MIRT2382443	hsa-miR-548ae	CLIP-seq
MIRT2382444	hsa-miR-548aj	CLIP-seq
MIRT2382445	hsa-miR-548am	CLIP-seq
MIRT2163325	hsa-miR-548e	CLIP-seq
MIRT2163326	hsa-miR-548f	CLIP-seq
MIRT2382446	hsa-miR-548x	CLIP-seq
MIRT2382447	hsa-miR-555	CLIP-seq
MIRT2382448	hsa-miR-578	CLIP-seq
MIRT1540889	hsa-miR-579	CLIP-seq
MIRT2382449	hsa-miR-600	CLIP-seq
MIRT2163329	hsa-miR-617	CLIP-seq
MIRT2382450	hsa-miR-671-5p	CLIP-seq
MIRT1540903	hsa-miR-761	CLIP-seq
MIRT2382451	hsa-miR-764	CLIP-seq
MIRT1540905	hsa-miR-922	CLIP-seq
MIRT1540906	hsa-miR-938	CLIP-seq
MIRT1540772	hsa-miR-15a	CLIP-seq
MIRT1540773	hsa-miR-15b	CLIP-seq
MIRT1540774	hsa-miR-16	CLIP-seq
MIRT1540780	hsa-miR-195	CLIP-seq
MIRT2163285	hsa-miR-3155	CLIP-seq
MIRT2163286	hsa-miR-3155b	CLIP-seq
MIRT1540819	hsa-miR-424	CLIP-seq
MIRT2163317	hsa-miR-484	CLIP-seq
MIRT1540878	hsa-miR-497	CLIP-seq
MIRT2163321	hsa-miR-513c	CLIP-seq
MIRT2163322	hsa-miR-514b-5p	CLIP-seq
MIRT2163321	hsa-miR-513c	CLIP-seq
MIRT2163322	hsa-miR-514b-5p	CLIP-seq
MIRT2163285	hsa-miR-3155	CLIP-seq
MIRT2163286	hsa-miR-3155b	CLIP-seq
MIRT1540799	hsa-miR-3182	CLIP-seq
MIRT2163299	hsa-miR-4327	CLIP-seq
MIRT2163300	hsa-miR-4330	CLIP-seq
MIRT2163301	hsa-miR-4427	CLIP-seq
MIRT2673263	hsa-miR-4452	CLIP-seq
MIRT2163304	hsa-miR-4494	CLIP-seq
MIRT2163309	hsa-miR-4645-5p	CLIP-seq
MIRT2673264	hsa-miR-4659a-3p	CLIP-seq
MIRT2673265	hsa-miR-4659b-3p	CLIP-seq
MIRT2163312	hsa-miR-4673	CLIP-seq
MIRT2673266	hsa-miR-4680-3p	CLIP-seq
MIRT2163313	hsa-miR-4695-3p	CLIP-seq
MIRT2163315	hsa-miR-4762-3p	CLIP-seq
MIRT2163317	hsa-miR-484	CLIP-seq
MIRT2163319	hsa-miR-499a-5p	CLIP-seq
MIRT2163321	hsa-miR-513c	CLIP-seq
MIRT2163322	hsa-miR-514b-5p	CLIP-seq
MIRT2163329	hsa-miR-617	CLIP-seq
MIRT2163285	hsa-miR-3155	CLIP-seq
MIRT2163286	hsa-miR-3155b	CLIP-seq
MIRT1540799	hsa-miR-3182	CLIP-seq
MIRT2163299	hsa-miR-4327	CLIP-seq
MIRT2163300	hsa-miR-4330	CLIP-seq
MIRT2163301	hsa-miR-4427	CLIP-seq
MIRT2673263	hsa-miR-4452	CLIP-seq
MIRT2163304	hsa-miR-4494	CLIP-seq
MIRT2163309	hsa-miR-4645-5p	CLIP-seq
MIRT2673264	hsa-miR-4659a-3p	CLIP-seq
MIRT2673265	hsa-miR-4659b-3p	CLIP-seq
MIRT2163312	hsa-miR-4673	CLIP-seq
MIRT2673266	hsa-miR-4680-3p	CLIP-seq
MIRT2163313	hsa-miR-4695-3p	CLIP-seq
MIRT2163315	hsa-miR-4762-3p	CLIP-seq
MIRT2163317	hsa-miR-484	CLIP-seq
MIRT2163319	hsa-miR-499a-5p	CLIP-seq
MIRT2163321	hsa-miR-513c	CLIP-seq
MIRT2163322	hsa-miR-514b-5p	CLIP-seq
MIRT2163329	hsa-miR-617	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 314998
• HGNC: 13156
• e!Ensembl: ENSG00000197779

Protein

• UniProt ID: P51508
• Protein name: Zinc finger protein 81 (HFZ20)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	20 → 61	KRAB box	Family
  PF00096	zf-C2H2	330 → 352	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	358 → 380	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	386 → 408	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	414 → 436	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	442 → 464	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	470 → 492	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	498 → 520	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	526 → 548	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	554 → 576	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	582 → 604	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	610 → 632	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	638 → 660	Zinc finger, C2H2 type	Domain

• Sequence:

  MPANEDAPQPGEHGSACEVSVSFEDVTVDFSREEWQQLDSTQRRLYQDVMLENYSHLLSV
  GFEVPKPEVIFKLEQGEGPWTLEGEAPHQSCSDGKFGIKPSQRRISGKSTFHSEMEGEDT
  RDDSLYSILEELWQDAEQIKRCQEKHNKLLSRTTFLNKKILNTEWDYEYKDFGKFVHPSP
  NLILSQKRPHKRDSFGKSFKHNLDLHIHNKSNAAKNLDKTIGHGQVFTQNSSYSHHENTH
  TGVKFCERNQCGKVLSLKHSLSQNVKFPIGEKANTCTEFGKIFTQRSHFFAPQKIHTVEK
  PHELSKCVNVFTQKPLLSIYLRVHRDEKLYICTKCGKAFIQNSELIMHEKTHTREKPYKC
  NECGKSFFQVSSLLRHQTTHTGEKLFECSECGKGFSLNSALNIHQKIHTGERHHKCSECG
  KAFTQKSTLRMHQRIHTGERSYICTQCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFP
  SKSQLQMHKRIHTGEKPYICTECGKAFTNRSNLNTHQKSHTGEKSYICAECGKAFTDRSN
  FNKHQTIHTGEKPYVCADCGRAFIQKSELITHQRIHTTEKPYKCPDCEKSFSKKPHLKVH
  QRIHTGEKPYICAECGKAFTDRSNFNKHQTIHTGDKPYKCSDCGKGFTQKSVLSMHRNIH
  T

• Sequence length: 661

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Colon adenocarcinoma	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
History of neurodevelopmental disorder	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED 45	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Intellectual disability, X-linked 45	Uncertain significance	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Malignant tumor of urinary bladder	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL RETARDATION, X-LINKED NONSYNDROMIC	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Non-syndromic X-linked intellectual disability	Uncertain significance	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Ovarian serous cystadenocarcinoma	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED INTELLECTUAL DISABILITY	—	ClinGen	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
X-LINKED NON-SYNDROMIC INTELLECTUAL DISABILITY	—	Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ZNF81-related disorder	Benign; Uncertain significance; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
2-3 toe syndactyly	Syndactyly Of The Toes	HPO_DG			★☆☆☆☆ Found in Text Mining only
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	HPO_DG			★☆☆☆☆ Found in Text Mining only
Autistic behavior	Autism	HPO_DG			★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Developmental disability	Pubtator	30559312	Associate	★☆☆☆☆ Found in Text Mining only
Facial paralysis	Facial paralysis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	BEFREE	20186789, 22634100		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	23871722	Associate	★☆☆☆☆ Found in Text Mining only
Macrocephaly	Macrocephaly	HPO_DG			★☆☆☆☆ Found in Text Mining only
Meckel Diverticulum	Meckel Diverticulum	HPO_DG			★☆☆☆☆ Found in Text Mining only
Mental Retardation	Mental retardation	BEFREE	20186789, 22634100		★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked	Mental retardation	BEFREE	16385466		★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked	Mental retardation	GENOMICS_ENGLAND_DG			★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked 1	Mental Retardation, X-Linked	ORPHANET_DG	15121780		★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked 45	Mental Retardation, X-Linked	GENOMICS_ENGLAND_DG			★☆☆☆☆ Found in Text Mining only
Mental Retardation, X-Linked Nonsyndromic	Mental retardation	CLINGEN_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mild neurosensory hearing impairment	Neurosensory Hearing impairment	HPO_DG			★☆☆☆☆ Found in Text Mining only
Moderate intellectual disability	Mental retardation	HPO_DG			★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	HPO_DG			★☆☆☆☆ Found in Text Mining only
Severe intellectual disability	Mental retardation	HPO_DG			★☆☆☆☆ Found in Text Mining only
Tonic - clonic seizures	Seizure	HPO_DG			★☆☆☆☆ Found in Text Mining only
X-linked non-syndromic intellectual disability	Non-Syndromic Intellectual Disability, X-Linked	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations