Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	343472
Gene name	BarH like homeobox 2
Gene symbol	BARHL2
Synonyms (NCBI Gene)	-
Chromosome	1
Chromosome location	1p22.2

192

Show/Hide all (192)

miRTarBase ID	miRNA	Experiments	Reference
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT635366	hsa-miR-4490	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT616552	hsa-miR-4297	HITS-CLIP	23824327
MIRT616551	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT616550	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT540164	hsa-miR-33b-3p	PAR-CLIP	21572407
MIRT540163	hsa-miR-515-3p	PAR-CLIP	21572407
MIRT540162	hsa-miR-519e-3p	PAR-CLIP	21572407
MIRT540161	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT540160	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT540159	hsa-miR-6516-5p	PAR-CLIP	21572407
MIRT610513	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT610512	hsa-miR-3183	HITS-CLIP	28735896
MIRT635366	hsa-miR-4490	HITS-CLIP	28735896
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	28735896
MIRT610514	hsa-miR-483-3p	HITS-CLIP	28735896
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	28735896
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	28735896
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	28735896
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	28735896
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	28735896
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT635366	hsa-miR-4490	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT616552	hsa-miR-4297	HITS-CLIP	23824327
MIRT616551	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT616550	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT610514	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT610513	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT610512	hsa-miR-3183	HITS-CLIP	23824327
MIRT610511	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT610510	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT610509	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT610508	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT610507	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT610506	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT540164	hsa-miR-33b-3p	PAR-CLIP	21572407
MIRT540163	hsa-miR-515-3p	PAR-CLIP	21572407
MIRT540162	hsa-miR-519e-3p	PAR-CLIP	21572407
MIRT540161	hsa-miR-6499-3p	PAR-CLIP	21572407
MIRT540160	hsa-miR-455-3p	PAR-CLIP	21572407
MIRT540159	hsa-miR-6516-5p	PAR-CLIP	21572407

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0001709	Process	Cell fate determination	IEA
GO:0001764	Process	Neuron migration	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0007399	Process	Nervous system development	IEA
GO:0030182	Process	Neuron differentiation	IEA
GO:0030516	Process	Regulation of axon extension	IEA
GO:0035881	Process	Amacrine cell differentiation	IEA
GO:0045165	Process	Cell fate commitment	IEA
GO:0045727	Process	Positive regulation of translation	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
605212	954	ENSG00000143032

Q9NY43

Protein name

BarH-like 2 homeobox protein

Protein function

Potential regulator of neural basic helix-loop-helix genes.

PDB

8PM5 , 8PM7 , 8PMC , 8PMF , 8PMN , 8PMV , 8PN4 , 8PNA , 8PNC , 8R7Z

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	233 → 289	Homeodomain	Domain

Sequence

MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGT
APSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQP
PPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHE
SFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFS
DHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAE
AGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRV
LIHGLGPGGQPALNPLSSPIPGTPHPR

Sequence length

387

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CANNABIS DEPENDENCE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (8)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinogenesis	Carcinogenesis	Pubtator	37161008	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	Pubtator	29341468	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	37161008	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	22143938	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	27453340	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	19852759	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	29341468		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oculocerebrorenal Syndrome	Oculocerebrorenal syndrome	Pubtator	37082886	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

BARHL2 (BarH like homeobox 2)