AADACL4 (arylacetamide deacetylase like 4)

Gene

• Entrez ID: 343066
• Gene name: Arylacetamide deacetylase like 4
• Gene symbol: AADACL4
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1p36.21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT756744	hsa-miR-1	CLIP-seq
MIRT756745	hsa-miR-1303	CLIP-seq
MIRT756746	hsa-miR-206	CLIP-seq
MIRT756747	hsa-miR-3123	CLIP-seq
MIRT756748	hsa-miR-3925-5p	CLIP-seq
MIRT756749	hsa-miR-613	CLIP-seq
MIRT1923166	hsa-miR-1252	CLIP-seq
MIRT1923167	hsa-miR-1287	CLIP-seq
MIRT1923168	hsa-miR-3135b	CLIP-seq
MIRT1923169	hsa-miR-3202	CLIP-seq
MIRT1923170	hsa-miR-4261	CLIP-seq
MIRT1923171	hsa-miR-4473	CLIP-seq
MIRT1923172	hsa-miR-4496	CLIP-seq
MIRT1923173	hsa-miR-4533	CLIP-seq
MIRT1923174	hsa-miR-4671-3p	CLIP-seq
MIRT1923175	hsa-miR-512-3p	CLIP-seq
MIRT1923176	hsa-miR-520f	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0052689	Function	Carboxylic ester hydrolase activity	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5VUY2
• Protein name: Arylacetamide deacetylase-like 4 (EC 3.1.1.-)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07859	Abhydrolase_3	115 → 285	alpha/beta hydrolase fold	Domain
  PF07859	Abhydrolase_3	291 → 381	alpha/beta hydrolase fold	Domain

• Sequence:

  MAVPWLVLLLALPIFFLGVFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIF
  EKLGICSMPKFIRFLHDSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHG
  GATVFGSLDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALETY
  GVDPSRVVVCGESVGGAAVAAITQALVGRSDLPRIRAQVLIYPVVQAFCLQLPSFQQNQN
  VPLLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRGYQ
  PWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRL
  EDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI

• Sequence length: 407

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations