Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Other IDs Protein Associated diseases
Entrez ID	342527
Gene name	Smoothelin like 2
Gene symbol	SMTNL2
Synonyms (NCBI Gene)	-
Chromosome	17
Chromosome location	17p13.2

212

Show/Hide all (212)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018381	hsa-miR-335-5p	Microarray	18185580
MIRT694036	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT694035	hsa-miR-4293	HITS-CLIP	23313552
MIRT672052	hsa-miR-3714	HITS-CLIP	23824327
MIRT672051	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT672050	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT672049	hsa-miR-940	HITS-CLIP	23824327
MIRT672048	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT672047	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT672046	hsa-miR-3937	HITS-CLIP	23824327
MIRT672045	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT672044	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT672043	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT672042	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT672041	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT672040	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT672039	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT672038	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT672037	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT672036	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT672035	hsa-miR-3122	HITS-CLIP	23824327
MIRT672034	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT672033	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT672032	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630255	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630255	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT630254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630249	hsa-miR-3652	HITS-CLIP	23824327
MIRT630248	hsa-miR-4430	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630251	hsa-miR-4284	HITS-CLIP	23824327
MIRT630250	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630249	hsa-miR-3652	HITS-CLIP	23824327
MIRT630248	hsa-miR-4430	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630255	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT630254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630251	hsa-miR-4284	HITS-CLIP	23824327
MIRT630250	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630249	hsa-miR-3652	HITS-CLIP	23824327
MIRT630248	hsa-miR-4430	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT694036	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT694035	hsa-miR-4293	HITS-CLIP	23313552
MIRT672052	hsa-miR-3714	HITS-CLIP	23824327
MIRT672051	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT672050	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT672049	hsa-miR-940	HITS-CLIP	23824327
MIRT672048	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT672047	hsa-miR-6500-3p	HITS-CLIP	23824327
MIRT672046	hsa-miR-3937	HITS-CLIP	23824327
MIRT672045	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT672044	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT672043	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT672042	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT672041	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT672040	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT672039	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT672038	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT672037	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT672036	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT672035	hsa-miR-3122	HITS-CLIP	23824327
MIRT672034	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT672033	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT672032	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630255	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630255	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT630254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630249	hsa-miR-3652	HITS-CLIP	23824327
MIRT630248	hsa-miR-4430	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630251	hsa-miR-4284	HITS-CLIP	23824327
MIRT630250	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630249	hsa-miR-3652	HITS-CLIP	23824327
MIRT630248	hsa-miR-4430	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT630262	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT630261	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT630260	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT630259	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT630258	hsa-miR-3666	HITS-CLIP	23824327
MIRT630257	hsa-miR-4295	HITS-CLIP	23824327
MIRT630256	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT630255	hsa-miR-7158-5p	HITS-CLIP	23824327
MIRT630254	hsa-miR-3135b	HITS-CLIP	23824327
MIRT630253	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT630252	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT630251	hsa-miR-4284	HITS-CLIP	23824327
MIRT630250	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630249	hsa-miR-3652	HITS-CLIP	23824327
MIRT630248	hsa-miR-4430	HITS-CLIP	23824327
MIRT630247	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT630246	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT630245	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT630244	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT1373984	hsa-miR-29a	CLIP-seq
MIRT1373985	hsa-miR-29b	CLIP-seq
MIRT1373986	hsa-miR-29c	CLIP-seq
MIRT1373987	hsa-miR-4778-3p	CLIP-seq
MIRT1373988	hsa-miR-593	CLIP-seq
MIRT1373989	hsa-miR-1207-3p	CLIP-seq
MIRT1373990	hsa-miR-129-3p	CLIP-seq
MIRT1373991	hsa-miR-140-3p	CLIP-seq
MIRT1373992	hsa-miR-148a	CLIP-seq
MIRT1373993	hsa-miR-148b	CLIP-seq
MIRT1373994	hsa-miR-152	CLIP-seq
MIRT1373995	hsa-miR-214	CLIP-seq
MIRT1373996	hsa-miR-3619-5p	CLIP-seq
MIRT1373997	hsa-miR-383	CLIP-seq
MIRT1373998	hsa-miR-4291	CLIP-seq
MIRT1373999	hsa-miR-4679	CLIP-seq
MIRT1374000	hsa-miR-4687-3p	CLIP-seq
MIRT1374001	hsa-miR-4772-5p	CLIP-seq
MIRT1373987	hsa-miR-4778-3p	CLIP-seq
MIRT1374002	hsa-miR-512-3p	CLIP-seq
MIRT1374003	hsa-miR-626	CLIP-seq
MIRT1374004	hsa-miR-647	CLIP-seq
MIRT1374005	hsa-miR-761	CLIP-seq
MIRT1374006	hsa-miR-802	CLIP-seq
MIRT1374007	hsa-miR-922	CLIP-seq
MIRT2460048	hsa-miR-103a	CLIP-seq
MIRT2460049	hsa-miR-107	CLIP-seq
MIRT2460050	hsa-miR-1184	CLIP-seq
MIRT2460051	hsa-miR-1205	CLIP-seq
MIRT2460052	hsa-miR-3158-5p	CLIP-seq
MIRT2460053	hsa-miR-340	CLIP-seq
MIRT2460054	hsa-miR-4686	CLIP-seq
MIRT2460055	hsa-miR-545	CLIP-seq

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q2TAL5

Protein name

Smoothelin-like protein 2

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00307	CH	351 → 459	Calponin homology (CH) domain	Domain

Sequence

MEPAPDAQEARTVREALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAMRLAGPLARTV
ADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTPSPPPAPGVPDRAPRLGSARF
ASHATFSLSGRGQSLDHDEASESEMRKTSNSCIMENGHQPGAGPGDGPPEIAQNFSAPDP
PRPRPVSLSLRLPHQPVTAITRVSDRFSGETSAAALSPMSAATLGGLNPSPSEVITPWTP
SPSEKNSSFTWSVPSSGYGAVTASKHSNSPPLVTPPQSPVSPQPPAITQVHRQGERRREL
VRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQSFGVASASSIKQILLEW
CRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAE
NLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRRFE

Sequence length

461

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
RHEUMATOID ARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	28118524	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Rheumatoid Arthritis	Rheumatoid arthritis	GWASCAT_DG	28118524	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

SMTNL2 (smoothelin like 2)