ZC3H12B (zinc finger CCCH-type containing 12B)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 340554 |
| Gene name | Zinc finger CCCH-type containing 12B |
| Gene symbol | ZC3H12B |
| Synonyms (NCBI Gene) |
CXorf32MCPIP2
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| Chromosome | X |
| Chromosome location | Xq11.2-q12 |
| Summary | The protein encoded by this gene belongs to a family of CCCH-type zinc finger proteins that are involved in the proinflammatory activation of macrophages. The exact function of this family member is unknown, but it is thought to function as a ribonuclease |
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miRNA
miRNA information provided by mirtarbase database.
615
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q5HYM0 | ||||||||||||||||||||
| Protein name | Probable ribonuclease ZC3H12B (EC 3.1.-.-) (MCP-induced protein 2) (Zinc finger CCCH domain-containing protein 12B) | ||||||||||||||||||||
| Protein function | May function as RNase and regulate the levels of target RNA species. | ||||||||||||||||||||
| PDB | 6SJD | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 836 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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