SLC35E4 (solute carrier family 35 member E4)

Gene

• Entrez ID: 339665
• Gene name: Solute carrier family 35 member E4
• Gene symbol: SLC35E4
• Synonyms (NCBI Gene): -
• Chromosome: 22
• Chromosome location: 22q12.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT646861	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT646860	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT646859	hsa-miR-5088-5p	HITS-CLIP	23824327
MIRT646858	hsa-miR-1245a	HITS-CLIP	23824327
MIRT646856	hsa-miR-8079	HITS-CLIP	23824327
MIRT646857	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT646855	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT646854	hsa-miR-4685-5p	HITS-CLIP	23824327
MIRT646853	hsa-miR-6837-5p	HITS-CLIP	23824327
MIRT646852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT646851	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT646850	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT646849	hsa-miR-4437	HITS-CLIP	23824327
MIRT646848	hsa-miR-1260a	HITS-CLIP	23824327
MIRT646847	hsa-miR-1260b	HITS-CLIP	23824327
MIRT646846	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT641005	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT641004	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT641003	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT641002	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT641001	hsa-miR-4775	HITS-CLIP	23824327
MIRT641000	hsa-miR-7159-3p	HITS-CLIP	23824327
MIRT640999	hsa-miR-4482-3p	HITS-CLIP	23824327
MIRT646861	hsa-miR-6819-3p	HITS-CLIP	23824327
MIRT646860	hsa-miR-6877-3p	HITS-CLIP	23824327
MIRT646859	hsa-miR-5088-5p	HITS-CLIP	23824327
MIRT646858	hsa-miR-1245a	HITS-CLIP	23824327
MIRT646856	hsa-miR-8079	HITS-CLIP	23824327
MIRT646857	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT646855	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT646854	hsa-miR-4685-5p	HITS-CLIP	23824327
MIRT646853	hsa-miR-6837-5p	HITS-CLIP	23824327
MIRT646852	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT646851	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT646850	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT646849	hsa-miR-4437	HITS-CLIP	23824327
MIRT646848	hsa-miR-1260a	HITS-CLIP	23824327
MIRT646847	hsa-miR-1260b	HITS-CLIP	23824327
MIRT646846	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT641005	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT641004	hsa-miR-6872-3p	HITS-CLIP	23824327
MIRT641003	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT641002	hsa-miR-138-2-3p	HITS-CLIP	23824327
MIRT641001	hsa-miR-4775	HITS-CLIP	23824327
MIRT641000	hsa-miR-7159-3p	HITS-CLIP	23824327
MIRT640999	hsa-miR-4482-3p	HITS-CLIP	23824327
MIRT1361558	hsa-miR-1207-5p	CLIP-seq
MIRT1361559	hsa-miR-122	CLIP-seq
MIRT1361560	hsa-miR-1254	CLIP-seq
MIRT1361561	hsa-miR-125a-3p	CLIP-seq
MIRT1361562	hsa-miR-1271	CLIP-seq
MIRT1361563	hsa-miR-1275	CLIP-seq
MIRT1361564	hsa-miR-1287	CLIP-seq
MIRT1361565	hsa-miR-1299	CLIP-seq
MIRT1361566	hsa-miR-150	CLIP-seq
MIRT1361567	hsa-miR-1827	CLIP-seq
MIRT1361568	hsa-miR-1909	CLIP-seq
MIRT1361569	hsa-miR-1915	CLIP-seq
MIRT1361570	hsa-miR-1972	CLIP-seq
MIRT1361571	hsa-miR-22	CLIP-seq
MIRT1361572	hsa-miR-302a	CLIP-seq
MIRT1361573	hsa-miR-302b	CLIP-seq
MIRT1361574	hsa-miR-302c	CLIP-seq
MIRT1361575	hsa-miR-302d	CLIP-seq
MIRT1361576	hsa-miR-302e	CLIP-seq
MIRT1361577	hsa-miR-3116	CLIP-seq
MIRT1361578	hsa-miR-3135b	CLIP-seq
MIRT1361579	hsa-miR-3176	CLIP-seq
MIRT1361580	hsa-miR-3652	CLIP-seq
MIRT1361581	hsa-miR-3688-5p	CLIP-seq
MIRT1361582	hsa-miR-372	CLIP-seq
MIRT1361583	hsa-miR-373	CLIP-seq
MIRT1361584	hsa-miR-3917	CLIP-seq
MIRT1361585	hsa-miR-3922-3p	CLIP-seq
MIRT1361586	hsa-miR-3934	CLIP-seq
MIRT1361587	hsa-miR-4254	CLIP-seq
MIRT1361588	hsa-miR-4316	CLIP-seq
MIRT1361589	hsa-miR-4320	CLIP-seq
MIRT1361590	hsa-miR-4430	CLIP-seq
MIRT1361591	hsa-miR-4514	CLIP-seq
MIRT1361592	hsa-miR-4522	CLIP-seq
MIRT1361593	hsa-miR-4650-5p	CLIP-seq
MIRT1361594	hsa-miR-4653-3p	CLIP-seq
MIRT1361595	hsa-miR-4665-5p	CLIP-seq
MIRT1361596	hsa-miR-4692	CLIP-seq
MIRT1361597	hsa-miR-4710	CLIP-seq
MIRT1361598	hsa-miR-4713-5p	CLIP-seq
MIRT1361599	hsa-miR-4715-5p	CLIP-seq
MIRT1361600	hsa-miR-4717-5p	CLIP-seq
MIRT1361601	hsa-miR-4726-3p	CLIP-seq
MIRT1361602	hsa-miR-4731-5p	CLIP-seq
MIRT1361603	hsa-miR-4736	CLIP-seq
MIRT1361604	hsa-miR-4757-5p	CLIP-seq
MIRT1361605	hsa-miR-4763-3p	CLIP-seq
MIRT1361606	hsa-miR-485-5p	CLIP-seq
MIRT1361607	hsa-miR-512-3p	CLIP-seq
MIRT1361608	hsa-miR-520a-3p	CLIP-seq
MIRT1361609	hsa-miR-520b	CLIP-seq
MIRT1361610	hsa-miR-520c-3p	CLIP-seq
MIRT1361611	hsa-miR-520d-3p	CLIP-seq
MIRT1361612	hsa-miR-520e	CLIP-seq
MIRT1361613	hsa-miR-571	CLIP-seq
MIRT1361614	hsa-miR-640	CLIP-seq
MIRT1361615	hsa-miR-646	CLIP-seq
MIRT1361616	hsa-miR-658	CLIP-seq
MIRT1361617	hsa-miR-661	CLIP-seq
MIRT1361618	hsa-miR-764	CLIP-seq
MIRT1361619	hsa-miR-875-3p	CLIP-seq
MIRT1361620	hsa-miR-940	CLIP-seq
MIRT1361621	hsa-miR-96	CLIP-seq
MIRT1361561	hsa-miR-125a-3p	CLIP-seq
MIRT1361564	hsa-miR-1287	CLIP-seq
MIRT1361570	hsa-miR-1972	CLIP-seq
MIRT1361579	hsa-miR-3176	CLIP-seq
MIRT1361580	hsa-miR-3652	CLIP-seq
MIRT1361585	hsa-miR-3922-3p	CLIP-seq
MIRT1361586	hsa-miR-3934	CLIP-seq
MIRT2107139	hsa-miR-4289	CLIP-seq
MIRT1361589	hsa-miR-4320	CLIP-seq
MIRT1361590	hsa-miR-4430	CLIP-seq
MIRT1361593	hsa-miR-4650-5p	CLIP-seq
MIRT1361604	hsa-miR-4757-5p	CLIP-seq
MIRT1361606	hsa-miR-485-5p	CLIP-seq
MIRT2107140	hsa-miR-616	CLIP-seq
MIRT1361614	hsa-miR-640	CLIP-seq
MIRT1361616	hsa-miR-658	CLIP-seq
MIRT1361618	hsa-miR-764	CLIP-seq
MIRT1361559	hsa-miR-122	CLIP-seq
MIRT1361561	hsa-miR-125a-3p	CLIP-seq
MIRT1361566	hsa-miR-150	CLIP-seq
MIRT1361569	hsa-miR-1915	CLIP-seq
MIRT1361578	hsa-miR-3135b	CLIP-seq
MIRT1361579	hsa-miR-3176	CLIP-seq
MIRT1361580	hsa-miR-3652	CLIP-seq
MIRT2331231	hsa-miR-3663-5p	CLIP-seq
MIRT1361585	hsa-miR-3922-3p	CLIP-seq
MIRT1361586	hsa-miR-3934	CLIP-seq
MIRT1361590	hsa-miR-4430	CLIP-seq
MIRT2331232	hsa-miR-4662a-5p	CLIP-seq
MIRT2331233	hsa-miR-4676-5p	CLIP-seq
MIRT1361598	hsa-miR-4713-5p	CLIP-seq
MIRT2331234	hsa-miR-4716-5p	CLIP-seq
MIRT1361601	hsa-miR-4726-3p	CLIP-seq
MIRT2331235	hsa-miR-4755-3p	CLIP-seq
MIRT1361604	hsa-miR-4757-5p	CLIP-seq
MIRT2331236	hsa-miR-575	CLIP-seq
MIRT1361614	hsa-miR-640	CLIP-seq
MIRT1361618	hsa-miR-764	CLIP-seq
MIRT1361569	hsa-miR-1915	CLIP-seq
MIRT1361558	hsa-miR-1207-5p	CLIP-seq
MIRT2625679	hsa-miR-1227	CLIP-seq
MIRT2625680	hsa-miR-143	CLIP-seq
MIRT2625681	hsa-miR-1825	CLIP-seq
MIRT2625682	hsa-miR-199a-5p	CLIP-seq
MIRT2625683	hsa-miR-199b-5p	CLIP-seq
MIRT2625684	hsa-miR-2467-3p	CLIP-seq
MIRT2625685	hsa-miR-3199	CLIP-seq
MIRT2625686	hsa-miR-3650	CLIP-seq
MIRT2625687	hsa-miR-3678-3p	CLIP-seq
MIRT2625688	hsa-miR-3944-5p	CLIP-seq
MIRT2625689	hsa-miR-411	CLIP-seq
MIRT2625690	hsa-miR-4535	CLIP-seq
MIRT2331235	hsa-miR-4755-3p	CLIP-seq
MIRT1361605	hsa-miR-4763-3p	CLIP-seq
MIRT2625691	hsa-miR-4770	CLIP-seq
MIRT2625692	hsa-miR-4776-5p	CLIP-seq
MIRT2625693	hsa-miR-711	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005794	Component	Golgi apparatus	IBA
GO:0015297	Function	Antiporter activity	IBA
GO:0016020	Component	Membrane	IEA
GO:0055085	Process	Transmembrane transport	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6ICL7
• Protein name: Solute carrier family 35 member E4
• Protein function: Putative transporter.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03151	TPT	47 → 326	Triose-phosphate Transporter family	Family

• Sequence:

  MCRCPPEHHDGRMTSAEVGAAAGGAQAAGPPEWPPGSPQALRQPGRARVAMAALVWLLAG
  ASMSSLNKWIFTVHGFGRPLLLSALHMLVAALACHRGARRPMPGGTRCRVLLLSLTFGTS
  MACGNVGLRAVPLDLAQLVTTTTPLFTLALSALLLGRRHHPLQLAAMGPLCLGAACSLAG
  EFRTPPTGCGFLLAATCLRGLKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVLE
  AGVAPPPTAGDSRLWACILLSCLLSVLYNLASFSLLALTSALTVHVLGNLTVVGNLILSR
  LLFGSRLSALSYVGIALTLSGMFLYHNCEFVASWAARRGLWRRDQPSKGL

• Sequence length: 350

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations