TMEM52 (transmembrane protein 52)

Gene

• Entrez ID: 339456
• Gene name: Transmembrane protein 52
• Gene symbol: TMEM52
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1p36.33

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1437885	hsa-miR-1224-3p	CLIP-seq
MIRT1437886	hsa-miR-125a-5p	CLIP-seq
MIRT1437887	hsa-miR-125b	CLIP-seq
MIRT1437888	hsa-miR-1260	CLIP-seq
MIRT1437889	hsa-miR-1260b	CLIP-seq
MIRT1437890	hsa-miR-1280	CLIP-seq
MIRT1437891	hsa-miR-1291	CLIP-seq
MIRT1437892	hsa-miR-3166	CLIP-seq
MIRT1437893	hsa-miR-328	CLIP-seq
MIRT1437894	hsa-miR-3670	CLIP-seq
MIRT1437895	hsa-miR-4319	CLIP-seq
MIRT1437896	hsa-miR-4771	CLIP-seq
MIRT1437897	hsa-miR-513a-5p	CLIP-seq
MIRT1437898	hsa-miR-515-5p	CLIP-seq
MIRT1437899	hsa-miR-532-3p	CLIP-seq
MIRT1437900	hsa-miR-552	CLIP-seq
MIRT1437901	hsa-miR-663b	CLIP-seq
MIRT2461831	hsa-miR-4768-5p	CLIP-seq
MIRT1437898	hsa-miR-515-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8NDY8
• Protein name: Transmembrane protein 52
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14979	TMEM52	36 → 184		Family

• Sequence:

  MARGPLAARGLRLLLPLLPLLPLLPLPQVALGFADGSCDPSDQCPPQARWSSLWHVGLIL
  LAVLLLLLCGVTAGCVRFCCLRKQAQAQPHLPPARQPCDVAVIPMDSDSPVHSTVTSYSS
  VQYPLGMRLPLPFGELDLDSMAPPAYSLYTPEPPPSYDEAVKMAKPREEGPALSQKPSPL
  LGASGLETTPVPQESGPNTQLPPCSPGAP

• Sequence length: 209

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ESTROGEN-RECEPTOR NEGATIVE BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESTROGEN-RECEPTOR POSITIVE BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations