Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	3232
Gene name	Homeobox D3
Gene symbol	HOXD3
Synonyms (NCBI Gene)	HOX1DHOX4HOX4AHox-4.1
Chromosome	2
Chromosome location	2q31.1
Summary	This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene cluster

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miRTarBase ID	miRNA	Experiments	Reference
MIRT050780	hsa-miR-17-3p	CLASH	23622248
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT484662	hsa-miR-6087	PAR-CLIP	20371350
MIRT484661	hsa-miR-6132	PAR-CLIP	20371350
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	20371350
MIRT484658	hsa-miR-3960	PAR-CLIP	20371350
MIRT484656	hsa-miR-8072	PAR-CLIP	20371350
MIRT484657	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT484653	hsa-miR-4467	PAR-CLIP	20371350
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT484662	hsa-miR-6087	PAR-CLIP	20371350
MIRT484661	hsa-miR-6132	PAR-CLIP	20371350
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	20371350
MIRT484658	hsa-miR-3960	PAR-CLIP	20371350
MIRT484656	hsa-miR-8072	PAR-CLIP	20371350
MIRT484657	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT484653	hsa-miR-4467	PAR-CLIP	20371350
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT484666	hsa-miR-4324	PAR-CLIP	20371350
MIRT484665	hsa-miR-4329	PAR-CLIP	20371350
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	20371350
MIRT484663	hsa-miR-769-5p	PAR-CLIP	20371350
MIRT484662	hsa-miR-6087	PAR-CLIP	20371350
MIRT484661	hsa-miR-6132	PAR-CLIP	20371350
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	20371350
MIRT484658	hsa-miR-3960	PAR-CLIP	20371350
MIRT484656	hsa-miR-8072	PAR-CLIP	20371350
MIRT484657	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT484653	hsa-miR-4467	PAR-CLIP	20371350
MIRT484668	hsa-miR-335-5p	PAR-CLIP	23592263
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT484666	hsa-miR-4324	PAR-CLIP	23592263
MIRT484665	hsa-miR-4329	PAR-CLIP	23592263
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	23592263
MIRT484663	hsa-miR-769-5p	PAR-CLIP	23592263
MIRT484662	hsa-miR-6087	PAR-CLIP	23592263
MIRT484661	hsa-miR-6132	PAR-CLIP	23592263
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	23592263
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT484658	hsa-miR-3960	PAR-CLIP	23592263
MIRT484656	hsa-miR-8072	PAR-CLIP	23592263
MIRT484657	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT484653	hsa-miR-4467	PAR-CLIP	23592263
MIRT484668	hsa-miR-335-5p	PAR-CLIP	23592263
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT484666	hsa-miR-4324	PAR-CLIP	23592263
MIRT484665	hsa-miR-4329	PAR-CLIP	23592263
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	23592263
MIRT484663	hsa-miR-769-5p	PAR-CLIP	23592263
MIRT484662	hsa-miR-6087	PAR-CLIP	23592263
MIRT484661	hsa-miR-6132	PAR-CLIP	23592263
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	23592263
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT484658	hsa-miR-3960	PAR-CLIP	23592263
MIRT484656	hsa-miR-8072	PAR-CLIP	23592263
MIRT484657	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT484653	hsa-miR-4467	PAR-CLIP	23592263
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484657	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT484668	hsa-miR-335-5p	PAR-CLIP	26701625
MIRT484668	hsa-miR-335-5p	PAR-CLIP	26701625
MIRT484668	hsa-miR-335-5p	PAR-CLIP	26701625
MIRT484668	hsa-miR-335-5p	PAR-CLIP	26701625
MIRT484668	hsa-miR-335-5p	PAR-CLIP	26701625
MIRT484668	hsa-miR-335-5p	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484658	hsa-miR-3960	PAR-CLIP	26701625
MIRT484666	hsa-miR-4324	PAR-CLIP	26701625
MIRT484666	hsa-miR-4324	PAR-CLIP	26701625
MIRT484665	hsa-miR-4329	PAR-CLIP	26701625
MIRT484665	hsa-miR-4329	PAR-CLIP	26701625
MIRT484665	hsa-miR-4329	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484653	hsa-miR-4467	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	26701625
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	26701625
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	26701625
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484662	hsa-miR-6087	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484661	hsa-miR-6132	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	26701625
MIRT484663	hsa-miR-769-5p	PAR-CLIP	26701625
MIRT484663	hsa-miR-769-5p	PAR-CLIP	26701625
MIRT484663	hsa-miR-769-5p	PAR-CLIP	26701625
MIRT484663	hsa-miR-769-5p	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484656	hsa-miR-8072	PAR-CLIP	26701625
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT484662	hsa-miR-6087	PAR-CLIP	20371350
MIRT484661	hsa-miR-6132	PAR-CLIP	20371350
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	20371350
MIRT484658	hsa-miR-3960	PAR-CLIP	20371350
MIRT484656	hsa-miR-8072	PAR-CLIP	20371350
MIRT484657	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT484653	hsa-miR-4467	PAR-CLIP	20371350
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT484662	hsa-miR-6087	PAR-CLIP	20371350
MIRT484661	hsa-miR-6132	PAR-CLIP	20371350
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	20371350
MIRT484658	hsa-miR-3960	PAR-CLIP	20371350
MIRT484656	hsa-miR-8072	PAR-CLIP	20371350
MIRT484657	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT484653	hsa-miR-4467	PAR-CLIP	20371350
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT484666	hsa-miR-4324	PAR-CLIP	20371350
MIRT484665	hsa-miR-4329	PAR-CLIP	20371350
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	20371350
MIRT484663	hsa-miR-769-5p	PAR-CLIP	20371350
MIRT484662	hsa-miR-6087	PAR-CLIP	20371350
MIRT484661	hsa-miR-6132	PAR-CLIP	20371350
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	20371350
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	20371350
MIRT484658	hsa-miR-3960	PAR-CLIP	20371350
MIRT484656	hsa-miR-8072	PAR-CLIP	20371350
MIRT484657	hsa-miR-31-5p	PAR-CLIP	20371350
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	20371350
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	20371350
MIRT484653	hsa-miR-4467	PAR-CLIP	20371350
MIRT484668	hsa-miR-335-5p	PAR-CLIP	23592263
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT484666	hsa-miR-4324	PAR-CLIP	23592263
MIRT484665	hsa-miR-4329	PAR-CLIP	23592263
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	23592263
MIRT484663	hsa-miR-769-5p	PAR-CLIP	23592263
MIRT484662	hsa-miR-6087	PAR-CLIP	23592263
MIRT484661	hsa-miR-6132	PAR-CLIP	23592263
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	23592263
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT484658	hsa-miR-3960	PAR-CLIP	23592263
MIRT484656	hsa-miR-8072	PAR-CLIP	23592263
MIRT484657	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT484653	hsa-miR-4467	PAR-CLIP	23592263
MIRT484668	hsa-miR-335-5p	PAR-CLIP	23592263
MIRT484667	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT484666	hsa-miR-4324	PAR-CLIP	23592263
MIRT484665	hsa-miR-4329	PAR-CLIP	23592263
MIRT484664	hsa-miR-4786-5p	PAR-CLIP	23592263
MIRT484663	hsa-miR-769-5p	PAR-CLIP	23592263
MIRT484662	hsa-miR-6087	PAR-CLIP	23592263
MIRT484661	hsa-miR-6132	PAR-CLIP	23592263
MIRT484660	hsa-miR-6836-5p	PAR-CLIP	23592263
MIRT484659	hsa-miR-6820-5p	PAR-CLIP	23592263
MIRT484658	hsa-miR-3960	PAR-CLIP	23592263
MIRT484656	hsa-miR-8072	PAR-CLIP	23592263
MIRT484657	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT484655	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT484654	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT484653	hsa-miR-4467	PAR-CLIP	23592263
MIRT1053781	hsa-miR-1323	CLIP-seq
MIRT1053782	hsa-miR-203	CLIP-seq
MIRT1053783	hsa-miR-299-3p	CLIP-seq
MIRT1053784	hsa-miR-31	CLIP-seq
MIRT1053785	hsa-miR-3173-3p	CLIP-seq
MIRT1053786	hsa-miR-3688-5p	CLIP-seq
MIRT1053787	hsa-miR-3689d	CLIP-seq
MIRT1053788	hsa-miR-4428	CLIP-seq
MIRT1053789	hsa-miR-4491	CLIP-seq
MIRT1053790	hsa-miR-4521	CLIP-seq
MIRT1053791	hsa-miR-4652-5p	CLIP-seq
MIRT1053792	hsa-miR-4657	CLIP-seq
MIRT1053793	hsa-miR-548o	CLIP-seq
MIRT1053794	hsa-miR-606	CLIP-seq
MIRT1053795	hsa-miR-663b	CLIP-seq

Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	7913891
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	14610084
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	23088713, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IC	12836255
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0006351	Process	DNA-templated transcription	IMP	12836255
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007160	Process	Cell-matrix adhesion	IDA	7742539
GO:0007219	Process	Notch signaling pathway	IMP	12836255
GO:0009952	Process	Anterior/posterior pattern specification	IBA
GO:0009952	Process	Anterior/posterior pattern specification	IEA
GO:0009952	Process	Anterior/posterior pattern specification	ISS
GO:0010628	Process	Positive regulation of gene expression	IMP	12836255
GO:0016235	Component	Aggresome	IDA
GO:0016604	Component	Nuclear body	IDA
GO:0021615	Process	Glossopharyngeal nerve morphogenesis	IEA
GO:0030878	Process	Thyroid gland development	IEA
GO:0030878	Process	Thyroid gland development	ISS
GO:0045666	Process	Positive regulation of neuron differentiation	IEA
GO:0045666	Process	Positive regulation of neuron differentiation	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	14610084
GO:0048704	Process	Embryonic skeletal system morphogenesis	IBA
GO:0048704	Process	Embryonic skeletal system morphogenesis	IEA
GO:0048704	Process	Embryonic skeletal system morphogenesis	ISS
GO:0051216	Process	Cartilage development	IEA
GO:0051216	Process	Cartilage development	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
142980	5137	ENSG00000128652

P31249

Protein name

Homeobox protein Hox-D3 (Homeobox protein Hox-4A)

Protein function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	195 → 251	Homeodomain	Domain
PF13293	DUF4074	369 → 430	Domain of unknown function (DUF4074)	Family

Sequence

MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD
TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP
PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA
GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI
WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP
AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG
NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ
GRLPEAPKLTHL

Sequence length

432

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
MALIGNANT EPITHELIAL TUMOR OF OVARY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBSTRUCTIVE SLEEP APNEA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN MUCINOUS ADENOCARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN SEROUS CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PELVIC ORGAN PROLAPSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (42)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute Erythroblastic Leukemia	Erythroblastic Leukemia	BEFREE	7742539		★★★★★ ★☆☆☆☆ Found in Text Mining only
Acute Promyelocytic Leukemia	Promyelocytic Leukemia	BEFREE	7742539		★★★★★ ★☆☆☆☆ Found in Text Mining only
Benign Prostatic Hyperplasia	Benign Prostatic Hyperplasia	BEFREE	24938434		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	29698974		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	28691018, 29698974	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	34028973	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	28418032, 29402992, 32557953, 34028973	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	11477555, 12405287, 25802847		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	26391404	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	37827698	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	29262571		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	27499213, 30823921		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	27499213	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	31777602		★★★★★ ★☆☆☆☆ Found in Text Mining only
Duane Retraction Syndrome	Duane Retraction Syndrome	LHGDN	17126050		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	35594842, 40209540	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	18404365	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	LHGDN	17785556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	27244890, 29402992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	25802847	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	29698974		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	11477555, 12405287, 25802847		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	29262571		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	19283074, 21207416, 22452941, 24651255, 24718283, 24847526, 24938434, 30470249		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	CTD_human_DG	19283074		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	31287793		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	24847526, 27499213, 29698974		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	12405287		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	LHGDN	12405287		★★★★★ ★☆☆☆☆ Found in Text Mining only
Motion Sickness	Motion Sickness	GWASCAT_DG	25628336		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	24718283, 24847526, 25193465		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	23144874	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Mucinous Adenocarcinoma	Ovarian adenocarcinoma	GWASCAT_DG	26075790, 28346442		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ovarian neoplasm	Ovarian neoplasm	GWASCAT_DG	28346442		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	29262571		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	22253144, 36213580	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Serous Adenocarcinoma	Ovarian serous adenocarcinoma	GWASCAT_DG	28346442		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	21207416, 22452941, 24651255, 24718283, 24847526, 24938434, 30470249		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	CTD_human_DG	19283074		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	19283074, 20212450, 24651255, 24718283, 24847526, 24938434, 30470249, 31605802	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Stomach Carcinoma	Stomach Carcinoma	BEFREE	31287793		★★★★★ ★☆☆☆☆ Found in Text Mining only
Testicular Germ Cell Tumor	Testicular germ cell tumor	Pubtator	37827698	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only

HOXD3 (homeobox D3)