Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	3131
Gene name	HLF transcription factor, PAR bZIP family member
Gene symbol	HLF
Synonyms (NCBI Gene)	-
Chromosome	17
Chromosome location	17q22
Summary	This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to

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Show/Hide all (274)

miRTarBase ID	miRNA	Experiments	Reference
MIRT715185	hsa-miR-29a-5p	HITS-CLIP	19536157
MIRT612902	hsa-miR-8485	HITS-CLIP	23313552
MIRT612901	hsa-miR-603	HITS-CLIP	23313552
MIRT702941	hsa-miR-374c-3p	HITS-CLIP	23313552
MIRT612900	hsa-miR-600	HITS-CLIP	23313552
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT614624	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614623	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT614621	hsa-miR-4643	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT614620	hsa-miR-3941	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT614624	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614623	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT614622	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT614621	hsa-miR-4643	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT614620	hsa-miR-3941	HITS-CLIP	23824327
MIRT614619	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT443770	hsa-miR-5692a	PAR-CLIP	22100165
MIRT443768	hsa-miR-5197-5p	PAR-CLIP	22100165
MIRT443769	hsa-miR-664a-3p	PAR-CLIP	22100165
MIRT443767	hsa-miR-4289	PAR-CLIP	22100165
MIRT443766	hsa-miR-4320	PAR-CLIP	22100165
MIRT443765	hsa-miR-3926	PAR-CLIP	22100165
MIRT443764	hsa-miR-569	PAR-CLIP	22100165
MIRT443763	hsa-miR-548s	PAR-CLIP	22100165
MIRT443762	hsa-miR-2053	PAR-CLIP	22100165
MIRT443761	hsa-miR-5004-3p	PAR-CLIP	22100165
MIRT612900	hsa-miR-600	HITS-CLIP	27418678
MIRT612901	hsa-miR-603	HITS-CLIP	27418678
MIRT612902	hsa-miR-8485	HITS-CLIP	27418678
MIRT733884	hsa-miR-98-5p	Luciferase reporter assayWestern blottingChIP-seqqRT-PCR	32637414
MIRT715185	hsa-miR-29a-5p	HITS-CLIP	19536157
MIRT612902	hsa-miR-8485	HITS-CLIP	23313552
MIRT612901	hsa-miR-603	HITS-CLIP	23313552
MIRT702941	hsa-miR-374c-3p	HITS-CLIP	23313552
MIRT612900	hsa-miR-600	HITS-CLIP	23313552
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT614624	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614623	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT614621	hsa-miR-4643	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT614620	hsa-miR-3941	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT614624	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT614623	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT614622	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT614621	hsa-miR-4643	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT614620	hsa-miR-3941	HITS-CLIP	23824327
MIRT614619	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT612902	hsa-miR-8485	HITS-CLIP	23824327
MIRT612901	hsa-miR-603	HITS-CLIP	23824327
MIRT612900	hsa-miR-600	HITS-CLIP	23824327
MIRT443770	hsa-miR-5692a	PAR-CLIP	22100165
MIRT443768	hsa-miR-5197-5p	PAR-CLIP	22100165
MIRT443769	hsa-miR-664a-3p	PAR-CLIP	22100165
MIRT443767	hsa-miR-4289	PAR-CLIP	22100165
MIRT443766	hsa-miR-4320	PAR-CLIP	22100165
MIRT443765	hsa-miR-3926	PAR-CLIP	22100165
MIRT443764	hsa-miR-569	PAR-CLIP	22100165
MIRT443763	hsa-miR-548s	PAR-CLIP	22100165
MIRT443762	hsa-miR-2053	PAR-CLIP	22100165
MIRT443761	hsa-miR-5004-3p	PAR-CLIP	22100165
MIRT1048663	hsa-miR-1193	CLIP-seq
MIRT1048664	hsa-miR-1227	CLIP-seq
MIRT1048665	hsa-miR-181a	CLIP-seq
MIRT1048666	hsa-miR-181b	CLIP-seq
MIRT1048667	hsa-miR-181c	CLIP-seq
MIRT1048668	hsa-miR-181d	CLIP-seq
MIRT1048669	hsa-miR-223	CLIP-seq
MIRT1048670	hsa-miR-2964a-5p	CLIP-seq
MIRT1048671	hsa-miR-29a	CLIP-seq
MIRT1048672	hsa-miR-29b	CLIP-seq
MIRT1048673	hsa-miR-29c	CLIP-seq
MIRT1048674	hsa-miR-325	CLIP-seq
MIRT1048675	hsa-miR-329	CLIP-seq
MIRT1048676	hsa-miR-3667-3p	CLIP-seq
MIRT1048677	hsa-miR-377	CLIP-seq
MIRT1048678	hsa-miR-3942-3p	CLIP-seq
MIRT1048679	hsa-miR-4252	CLIP-seq
MIRT1048680	hsa-miR-4262	CLIP-seq
MIRT1048681	hsa-miR-4264	CLIP-seq
MIRT1048682	hsa-miR-4268	CLIP-seq
MIRT1048683	hsa-miR-4697-3p	CLIP-seq
MIRT1048684	hsa-miR-4714-3p	CLIP-seq
MIRT1048685	hsa-miR-4716-5p	CLIP-seq
MIRT1048686	hsa-miR-4721	CLIP-seq
MIRT1048687	hsa-miR-4728-5p	CLIP-seq
MIRT1048688	hsa-miR-4777-5p	CLIP-seq
MIRT1048689	hsa-miR-4789-5p	CLIP-seq
MIRT1048690	hsa-miR-500a	CLIP-seq
MIRT1048691	hsa-miR-579	CLIP-seq
MIRT1048692	hsa-miR-622	CLIP-seq
MIRT1048693	hsa-miR-628-3p	CLIP-seq
MIRT1048694	hsa-miR-664	CLIP-seq
MIRT2011047	hsa-miR-2052	CLIP-seq
MIRT1048669	hsa-miR-223	CLIP-seq
MIRT2011048	hsa-miR-24	CLIP-seq
MIRT2011049	hsa-miR-3200-5p	CLIP-seq
MIRT2011050	hsa-miR-335	CLIP-seq
MIRT2011051	hsa-miR-4284	CLIP-seq
MIRT2011052	hsa-miR-4436b-5p	CLIP-seq
MIRT2011053	hsa-miR-452	CLIP-seq
MIRT2011054	hsa-miR-4676-3p	CLIP-seq
MIRT1048683	hsa-miR-4697-3p	CLIP-seq
MIRT2011055	hsa-miR-4766-5p	CLIP-seq
MIRT2243345	hsa-miR-106a	CLIP-seq
MIRT2243346	hsa-miR-106b	CLIP-seq
MIRT2243347	hsa-miR-17	CLIP-seq
MIRT2243348	hsa-miR-20a	CLIP-seq
MIRT2243349	hsa-miR-20b	CLIP-seq
MIRT1048670	hsa-miR-2964a-5p	CLIP-seq
MIRT2243350	hsa-miR-302a	CLIP-seq
MIRT2243351	hsa-miR-302b	CLIP-seq
MIRT2243352	hsa-miR-302c	CLIP-seq
MIRT2243353	hsa-miR-302d	CLIP-seq
MIRT2243354	hsa-miR-302e	CLIP-seq
MIRT1048675	hsa-miR-329	CLIP-seq
MIRT2243355	hsa-miR-3609	CLIP-seq
MIRT2243356	hsa-miR-372	CLIP-seq
MIRT2243357	hsa-miR-373	CLIP-seq
MIRT1048677	hsa-miR-377	CLIP-seq
MIRT2243358	hsa-miR-4286	CLIP-seq
MIRT2243359	hsa-miR-4318	CLIP-seq
MIRT2243360	hsa-miR-4490	CLIP-seq
MIRT2243361	hsa-miR-4796-3p	CLIP-seq
MIRT2243362	hsa-miR-512-3p	CLIP-seq
MIRT2243363	hsa-miR-519d	CLIP-seq
MIRT2243364	hsa-miR-520a-3p	CLIP-seq
MIRT2243365	hsa-miR-520b	CLIP-seq
MIRT2243366	hsa-miR-520c-3p	CLIP-seq
MIRT2243367	hsa-miR-520d-3p	CLIP-seq
MIRT2243368	hsa-miR-520e	CLIP-seq
MIRT2243369	hsa-miR-548ah	CLIP-seq
MIRT2243370	hsa-miR-93	CLIP-seq
MIRT2389028	hsa-miR-1205	CLIP-seq
MIRT2389029	hsa-miR-1324	CLIP-seq
MIRT2389030	hsa-miR-4536	CLIP-seq
MIRT2389031	hsa-miR-4790-3p	CLIP-seq
MIRT2451241	hsa-miR-128	CLIP-seq
MIRT2451242	hsa-miR-27a	CLIP-seq
MIRT2451243	hsa-miR-27b	CLIP-seq
MIRT2451244	hsa-miR-431	CLIP-seq
MIRT2451245	hsa-miR-4774-3p	CLIP-seq
MIRT2546523	hsa-miR-1184	CLIP-seq
MIRT2389028	hsa-miR-1205	CLIP-seq
MIRT2546524	hsa-miR-298	CLIP-seq
MIRT2546525	hsa-miR-3158-5p	CLIP-seq
MIRT2546526	hsa-miR-544	CLIP-seq

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	8065331
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	8065331
GO:0003677	Function	DNA binding	IEA
GO:0003677	Function	DNA binding	TAS	8639829
GO:0003690	Function	Double-stranded DNA binding	TAS	1386162
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	20102225, 21988832, 23661758
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	23661758
GO:0005634	Component	Nucleus	TAS	1386162
GO:0005654	Component	Nucleoplasm	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	NAS	23661758
GO:0035914	Process	Skeletal muscle cell differentiation	IEA
GO:0043565	Function	Sequence-specific DNA binding	IMP	8065331
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	8065331
GO:0048511	Process	Rhythmic process	IEA
GO:0090575	Component	RNA polymerase II transcription regulator complex	IPI	23661758
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
142385	4977	ENSG00000108924

Q16534

Protein name

Hepatic leukemia factor

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07716	bZIP_2	224 → 277	Basic region leucine zipper	Coiled-coil

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in liver; lower levels in lung and kidney.

Sequence

MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVP
QSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSAA
PSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPA
DLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAK
RSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Sequence length

295

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ANGIOEDEMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
B-LYMPHOBLASTIC LEUKEMIA/LYMPHOMA WITH T	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DILATED CARDIOMYOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GOUT	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEART FAILURE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTROPHIC CARDIOMYOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UNIPOLAR DEPRESSION	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
URTICARIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (55)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute lymphocytic leukemia	Lymphocytic Leukemia	BEFREE	1516826, 16206189, 16531271, 19887369, 20519628, 21072044, 22743623, 23181981, 26214592, 27088431, 31305009, 31735627, 31757791, 7518549, 8180393, 9737691 View all (1 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Acute monocytic leukemia	Monocytic Leukemia	BEFREE	31076446		★★★★★ ★☆☆☆☆ Found in Text Mining only
Acute Undifferentiated Leukemia	Leukemia	BEFREE	31076446		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Acute Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	20519628, 26214592, 27088431, 7518549		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis, Gouty	Gouty arthritis	GWASDB_DG	23263486		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar Disorder	GWASCAT_DG	31043756		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	39201344	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Leukemia	Burkitt`s Lymphoma	BEFREE	15147370		★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt`s Lymphoma	ORPHANET_DG	20519628		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	23991075	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	33099483	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	BEFREE	17183364, 20519628, 26214592, 27088431, 29334255, 7518549		★★★★★ ★☆☆☆☆ Found in Text Mining only
Childhood Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	CTD_human_DG	26214592		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	28402947	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	28178143		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fibrosis, Liver	Liver Fibrosis	BEFREE	28754776		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	33578515	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Gout	Gout	GWASDB_DG	23263486		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatoblastoma	Hepatoblastoma	BEFREE	1335479, 24811221		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypercalcemia	Hypercalcemia	BEFREE	15070701, 17183364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypercalcemia	Hypercalcemia	LHGDN	17183364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	30810067		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Failure	Kidney Failure	BEFREE	17183364		★★★★★ ★☆☆☆☆ Found in Text Mining only
L2 Acute Lymphoblastic Leukemia	Lymphoblastic Leukemia	CTD_human_DG	26214592		★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	12700034, 25740828, 27894958, 31735627, 8065331		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	17379095, 31735627, 8639829	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	LHGDN	18239067		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid	Myeloid leukemia	Pubtator	17379095	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	34876631	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	31076446		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	11857019, 1335479, 15585621, 22179686, 25189528, 25602745, 26996299, 29251327, 30176945		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	30867848, 34925645, 40124619	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphopenia	Lymphopenia	BEFREE	26588248		★★★★★ ★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	BEFREE	25880836		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Major Depressive Disorder	Mental Depression	PSYGENET_DG	25880836		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant neoplasm of liver	Liver Cancer	BEFREE	23407711		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	23415677, 27522003		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	11343236, 1335479, 27088431		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	24571258	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	37709768	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	23284986		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	23284986	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor B-cell acute lymphoblastic leukemia	Lymphoblastic Leukemia	Orphanet			★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor B-cell lymphoblastic leukemia	Lymphoblastic Leukemia	BEFREE	10086727, 10518215, 15070701, 15147370, 20519628, 21072044, 29334255, 8164688		★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor B-cell lymphoblastic leukemia	Lymphoblastic Leukemia	ORPHANET_DG	20519628		★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	Lymphoblastic Leukemia	BEFREE	10086727		★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor Cell Lymphoblastic Leukemia Lymphoma	Lymphoblastic Leukemia	BEFREE	1516826, 16206189, 16531271, 22743623, 23181981, 26214592, 31305009, 31735627, 31757791, 7518549, 8180393		★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor Cell Lymphoblastic Leukemia Lymphoma	Lymphoblastic Leukemia	LHGDN	16215946, 17183364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor Cell Lymphoblastic Leukemia Lymphoma	Lymphoblastic Leukemia	CTD_human_DG	26214592		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	25582705		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Insufficiency	Renal Insufficiency	BEFREE	17183364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinoblastoma	Retinoblastoma	BEFREE	11343236		★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinopathy of Prematurity	Retinopathy	BEFREE	12606578		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	31109699, 31562292	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Unipolar Depression	Mental Depression	PSYGENET_DG	25880836		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

HLF (HLF transcription factor, PAR bZIP family member)