Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	311
Gene name	Annexin A11
Gene symbol	ANXA11
Synonyms (NCBI Gene)	ALS23ANX11CAP-50CAP50IBMWMA
Chromosome	10
Chromosome location	10q22.3
Summary	This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded

Show/Hide all (4)

SNP ID	Visualize variation	Clinical significance	Consequence
rs142083484	C>T	Pathogenic	Missense variant, coding sequence variant
rs368751524	C>A,G	Likely-pathogenic	Coding sequence variant, missense variant
rs754594235	C>A,T	Pathogenic	Coding sequence variant, missense variant
rs1247392012	T>C	Pathogenic	Missense variant, coding sequence variant

192

Show/Hide all (192)

miRTarBase ID	miRNA	Experiments	Reference
MIRT003084	hsa-miR-122-5p	Luciferase reporter assayqRT-PCR	19296470
MIRT017220	hsa-miR-335-5p	Microarray	18185580
MIRT022375	hsa-miR-124-3p	Microarray	18668037
MIRT003084	hsa-miR-122-5p	Microarray	19296470
MIRT025684	hsa-miR-7-5p	Microarray	19073608
MIRT050326	hsa-miR-25-3p	CLASH	23622248
MIRT049835	hsa-miR-92a-3p	CLASH	23622248
MIRT044728	hsa-miR-320a	CLASH	23622248
MIRT042901	hsa-miR-324-3p	CLASH	23622248
MIRT042064	hsa-miR-484	CLASH	23622248
MIRT035979	hsa-miR-1301-3p	CLASH	23622248
MIRT539198	hsa-miR-4428	PAR-CLIP	22012620
MIRT539197	hsa-miR-3173-3p	PAR-CLIP	22012620
MIRT539196	hsa-miR-6891-5p	PAR-CLIP	22012620
MIRT539195	hsa-miR-548ag	PAR-CLIP	22012620
MIRT539194	hsa-miR-548ai	PAR-CLIP	22012620
MIRT539193	hsa-miR-548ba	PAR-CLIP	22012620
MIRT539192	hsa-miR-570-5p	PAR-CLIP	22012620
MIRT539191	hsa-miR-5088-5p	PAR-CLIP	22012620
MIRT539190	hsa-miR-4446-3p	PAR-CLIP	22012620
MIRT539189	hsa-miR-3158-3p	PAR-CLIP	22012620
MIRT539188	hsa-miR-505-5p	PAR-CLIP	22012620
MIRT539187	hsa-miR-4675	PAR-CLIP	22012620
MIRT539186	hsa-miR-4741	PAR-CLIP	22012620
MIRT449623	hsa-miR-4453	PAR-CLIP	22100165
MIRT449622	hsa-miR-4538	PAR-CLIP	22100165
MIRT449621	hsa-miR-5004-5p	PAR-CLIP	22100165
MIRT449620	hsa-miR-4751	PAR-CLIP	22100165
MIRT449619	hsa-miR-5579-3p	PAR-CLIP	22100165
MIRT449618	hsa-miR-1224-5p	PAR-CLIP	22100165
MIRT539198	hsa-miR-4428	PAR-CLIP	22012620
MIRT539197	hsa-miR-3173-3p	PAR-CLIP	22012620
MIRT539196	hsa-miR-6891-5p	PAR-CLIP	22012620
MIRT539195	hsa-miR-548ag	PAR-CLIP	22012620
MIRT539194	hsa-miR-548ai	PAR-CLIP	22012620
MIRT539193	hsa-miR-548ba	PAR-CLIP	22012620
MIRT539192	hsa-miR-570-5p	PAR-CLIP	22012620
MIRT539191	hsa-miR-5088-5p	PAR-CLIP	22012620
MIRT539190	hsa-miR-4446-3p	PAR-CLIP	22012620
MIRT539189	hsa-miR-3158-3p	PAR-CLIP	22012620
MIRT539188	hsa-miR-505-5p	PAR-CLIP	22012620
MIRT539187	hsa-miR-4675	PAR-CLIP	22012620
MIRT539186	hsa-miR-4741	PAR-CLIP	22012620
MIRT449623	hsa-miR-4453	PAR-CLIP	22100165
MIRT449622	hsa-miR-4538	PAR-CLIP	22100165
MIRT449621	hsa-miR-5004-5p	PAR-CLIP	22100165
MIRT449620	hsa-miR-4751	PAR-CLIP	22100165
MIRT449619	hsa-miR-5579-3p	PAR-CLIP	22100165
MIRT449618	hsa-miR-1224-5p	PAR-CLIP	22100165
MIRT786369	hsa-miR-1264	CLIP-seq
MIRT786370	hsa-miR-1294	CLIP-seq
MIRT786371	hsa-miR-15a	CLIP-seq
MIRT786372	hsa-miR-15b	CLIP-seq
MIRT786373	hsa-miR-16	CLIP-seq
MIRT786374	hsa-miR-195	CLIP-seq
MIRT786375	hsa-miR-3126-5p	CLIP-seq
MIRT786376	hsa-miR-3691-3p	CLIP-seq
MIRT786377	hsa-miR-424	CLIP-seq
MIRT786378	hsa-miR-4316	CLIP-seq
MIRT786379	hsa-miR-4419a	CLIP-seq
MIRT786380	hsa-miR-4510	CLIP-seq
MIRT786381	hsa-miR-451b	CLIP-seq
MIRT786382	hsa-miR-4524	CLIP-seq
MIRT786383	hsa-miR-4662a-5p	CLIP-seq
MIRT786384	hsa-miR-4677-3p	CLIP-seq
MIRT786385	hsa-miR-4742-5p	CLIP-seq
MIRT786386	hsa-miR-485-5p	CLIP-seq
MIRT786387	hsa-miR-497	CLIP-seq
MIRT786388	hsa-miR-503	CLIP-seq
MIRT786389	hsa-miR-646	CLIP-seq
MIRT786390	hsa-miR-298	CLIP-seq
MIRT786391	hsa-miR-3064-5p	CLIP-seq
MIRT786392	hsa-miR-3180-5p	CLIP-seq
MIRT786393	hsa-miR-3665	CLIP-seq
MIRT786394	hsa-miR-4423-5p	CLIP-seq
MIRT786395	hsa-miR-4487	CLIP-seq
MIRT786396	hsa-miR-4694-5p	CLIP-seq
MIRT786397	hsa-miR-4736	CLIP-seq
MIRT786398	hsa-miR-520a-5p	CLIP-seq
MIRT786399	hsa-miR-525-5p	CLIP-seq
MIRT786400	hsa-miR-541	CLIP-seq
MIRT786401	hsa-miR-654-5p	CLIP-seq
MIRT1931948	hsa-miR-3691-5p	CLIP-seq
MIRT1931949	hsa-miR-4752	CLIP-seq
MIRT786370	hsa-miR-1294	CLIP-seq
MIRT786371	hsa-miR-15a	CLIP-seq
MIRT786372	hsa-miR-15b	CLIP-seq
MIRT786373	hsa-miR-16	CLIP-seq
MIRT786374	hsa-miR-195	CLIP-seq
MIRT786390	hsa-miR-298	CLIP-seq
MIRT786375	hsa-miR-3126-5p	CLIP-seq
MIRT2172406	hsa-miR-3190	CLIP-seq
MIRT786393	hsa-miR-3665	CLIP-seq
MIRT786377	hsa-miR-424	CLIP-seq
MIRT786378	hsa-miR-4316	CLIP-seq
MIRT786379	hsa-miR-4419a	CLIP-seq
MIRT786394	hsa-miR-4423-5p	CLIP-seq
MIRT2172407	hsa-miR-4433	CLIP-seq
MIRT2172408	hsa-miR-4459	CLIP-seq
MIRT786380	hsa-miR-4510	CLIP-seq
MIRT786381	hsa-miR-451b	CLIP-seq
MIRT786382	hsa-miR-4524	CLIP-seq
MIRT2172409	hsa-miR-4651	CLIP-seq
MIRT786384	hsa-miR-4677-3p	CLIP-seq
MIRT786396	hsa-miR-4694-5p	CLIP-seq
MIRT2172410	hsa-miR-4704-3p	CLIP-seq
MIRT786397	hsa-miR-4736	CLIP-seq
MIRT2172411	hsa-miR-4768-3p	CLIP-seq
MIRT2172412	hsa-miR-4779	CLIP-seq
MIRT786386	hsa-miR-485-5p	CLIP-seq
MIRT786387	hsa-miR-497	CLIP-seq
MIRT786388	hsa-miR-503	CLIP-seq
MIRT786398	hsa-miR-520a-5p	CLIP-seq
MIRT786399	hsa-miR-525-5p	CLIP-seq
MIRT786400	hsa-miR-541	CLIP-seq
MIRT2172413	hsa-miR-608	CLIP-seq
MIRT786389	hsa-miR-646	CLIP-seq
MIRT786401	hsa-miR-654-5p	CLIP-seq
MIRT2172414	hsa-miR-7	CLIP-seq
MIRT2384258	hsa-miR-1281	CLIP-seq
MIRT786371	hsa-miR-15a	CLIP-seq
MIRT786372	hsa-miR-15b	CLIP-seq
MIRT786373	hsa-miR-16	CLIP-seq
MIRT786374	hsa-miR-195	CLIP-seq
MIRT2384259	hsa-miR-204	CLIP-seq
MIRT2384260	hsa-miR-211	CLIP-seq
MIRT2384261	hsa-miR-3622a-5p	CLIP-seq
MIRT786377	hsa-miR-424	CLIP-seq
MIRT2384262	hsa-miR-4287	CLIP-seq
MIRT786381	hsa-miR-451b	CLIP-seq
MIRT786382	hsa-miR-4524	CLIP-seq
MIRT2384263	hsa-miR-4685-3p	CLIP-seq
MIRT2384264	hsa-miR-4768-5p	CLIP-seq
MIRT786387	hsa-miR-497	CLIP-seq
MIRT786388	hsa-miR-503	CLIP-seq
MIRT786389	hsa-miR-646	CLIP-seq
MIRT2475331	hsa-miR-1290	CLIP-seq
MIRT2475332	hsa-miR-1914	CLIP-seq
MIRT786390	hsa-miR-298	CLIP-seq
MIRT2475333	hsa-miR-3167	CLIP-seq
MIRT2172406	hsa-miR-3190	CLIP-seq
MIRT786393	hsa-miR-3665	CLIP-seq
MIRT2475334	hsa-miR-3688-5p	CLIP-seq
MIRT1931948	hsa-miR-3691-5p	CLIP-seq
MIRT786394	hsa-miR-4423-5p	CLIP-seq
MIRT2172407	hsa-miR-4433	CLIP-seq
MIRT2172408	hsa-miR-4459	CLIP-seq
MIRT2475335	hsa-miR-4489	CLIP-seq
MIRT2475336	hsa-miR-4508	CLIP-seq
MIRT2475337	hsa-miR-4650-5p	CLIP-seq
MIRT2172409	hsa-miR-4651	CLIP-seq
MIRT786396	hsa-miR-4694-5p	CLIP-seq
MIRT2475338	hsa-miR-4726-3p	CLIP-seq
MIRT786397	hsa-miR-4736	CLIP-seq
MIRT1931949	hsa-miR-4752	CLIP-seq
MIRT2172411	hsa-miR-4768-3p	CLIP-seq
MIRT2172412	hsa-miR-4779	CLIP-seq
MIRT786400	hsa-miR-541	CLIP-seq
MIRT2475339	hsa-miR-551a	CLIP-seq
MIRT2475340	hsa-miR-551b	CLIP-seq
MIRT2172413	hsa-miR-608	CLIP-seq
MIRT786401	hsa-miR-654-5p	CLIP-seq
MIRT2172414	hsa-miR-7	CLIP-seq
MIRT2475341	hsa-miR-876-5p	CLIP-seq
MIRT2475331	hsa-miR-1290	CLIP-seq
MIRT2475332	hsa-miR-1914	CLIP-seq
MIRT786390	hsa-miR-298	CLIP-seq
MIRT2475333	hsa-miR-3167	CLIP-seq
MIRT2172406	hsa-miR-3190	CLIP-seq
MIRT786393	hsa-miR-3665	CLIP-seq
MIRT2475334	hsa-miR-3688-5p	CLIP-seq
MIRT1931948	hsa-miR-3691-5p	CLIP-seq
MIRT786394	hsa-miR-4423-5p	CLIP-seq
MIRT2172407	hsa-miR-4433	CLIP-seq
MIRT2172408	hsa-miR-4459	CLIP-seq
MIRT2475335	hsa-miR-4489	CLIP-seq
MIRT2475336	hsa-miR-4508	CLIP-seq
MIRT2475337	hsa-miR-4650-5p	CLIP-seq
MIRT2172409	hsa-miR-4651	CLIP-seq
MIRT786396	hsa-miR-4694-5p	CLIP-seq
MIRT2475338	hsa-miR-4726-3p	CLIP-seq
MIRT786397	hsa-miR-4736	CLIP-seq
MIRT1931949	hsa-miR-4752	CLIP-seq
MIRT2172411	hsa-miR-4768-3p	CLIP-seq
MIRT2172412	hsa-miR-4779	CLIP-seq
MIRT786400	hsa-miR-541	CLIP-seq
MIRT2475339	hsa-miR-551a	CLIP-seq
MIRT2475340	hsa-miR-551b	CLIP-seq
MIRT2172413	hsa-miR-608	CLIP-seq
MIRT786401	hsa-miR-654-5p	CLIP-seq
MIRT2172414	hsa-miR-7	CLIP-seq
MIRT2475341	hsa-miR-876-5p	CLIP-seq

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001786	Function	Phosphatidylserine binding	IBA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	9268363, 12445460, 15197175, 25910212, 31515488, 32296183
GO:0005544	Function	Calcium-dependent phospholipid binding	IBA
GO:0005544	Function	Calcium-dependent phospholipid binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005635	Component	Nuclear envelope	IDA	12601007, 15197175
GO:0005635	Component	Nuclear envelope	IEA
GO:0005635	Component	Nuclear envelope	NAS	12577318
GO:0005654	Component	Nucleoplasm	IDA	7508441, 12601007, 15197175
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	NAS	12577318
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	7508441, 12601007, 12805373
GO:0005737	Component	Cytoplasm	IEA
GO:0005819	Component	Spindle	IDA	12805373, 15197175
GO:0005819	Component	Spindle	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0006909	Process	Phagocytosis	IBA
GO:0006909	Process	Phagocytosis	IEP	9188810
GO:0008429	Function	Phosphatidylethanolamine binding	IEA
GO:0012506	Component	Vesicle membrane	IBA
GO:0016020	Component	Membrane	HDA	19946888
GO:0023026	Function	MHC class II protein complex binding	HDA	20458337
GO:0030496	Component	Midbody	IDA	15197175
GO:0031012	Component	Extracellular matrix	HDA	25037231, 28344315
GO:0032506	Process	Cytokinetic process	IBA
GO:0032506	Process	Cytokinetic process	IMP	15197175
GO:0042470	Component	Melanosome	IEA
GO:0042581	Component	Specific granule	IDA	9188810
GO:0042582	Component	Azurophil granule	IDA	9188810
GO:0044548	Function	S100 protein binding	IPI	12577318, 19724273
GO:0045335	Component	Phagocytic vesicle	IDA	9188810
GO:0048306	Function	Calcium-dependent protein binding	IPI	11883939, 12445460
GO:0051301	Process	Cell division	IEA
GO:0051592	Process	Response to calcium ion	IDA	9188810, 12601007
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337, 23533145

MIM	HGNC	e!Ensembl
602572	535	ENSG00000122359

P50995

Protein name

Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)

Protein function

Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.

PDB

9FOF , 9FOR

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00191	Annexin	204 → 269	Annexin	Family
PF00191	Annexin	276 → 341	Annexin	Family
PF00191	Annexin	359 → 425	Annexin	Family
PF00191	Annexin	435 → 500	Annexin	Family

Sequence

MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN
MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY
PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT
PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA
SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD
AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE
GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS
LYHDISGDTSGDYRKILLKICGGND

Sequence length

505

Interactions

View interactions

	KEGG
	Amyotrophic lateral sclerosis

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Amyotrophic lateral sclerosis	Likely pathogenic; Pathogenic	rs142083484	RCV003105971	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Amyotrophic lateral sclerosis type 23	Pathogenic; Likely pathogenic	rs1247392012, rs142083484, rs368751524	RCV000578138 RCV000578149 RCV000988396	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
ANXA11-related disorder	Pathogenic; Likely pathogenic	rs1247392012, rs142083484	RCV003403366 RCV003962641	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Inclusion body myopathy and brain white matter abnormalities	Likely pathogenic; Pathogenic	rs368751524	RCV001836926	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Oculopharyngeal muscular dystrophy 1	Pathogenic	rs2492172951	RCV005245546	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (21)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AMYOTROPHIC LATERAL SCLEROSIS 23	—	Disgenet, HPO Disgenet, HPO	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONNECTIVE TISSUE NEOPLASM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OPEN-ANGLE GLAUCOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SARCOIDOSIS	—	CTD, Disgenet, GWAS catalog CTD, Disgenet, GWAS catalog CTD, Disgenet, GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign; Likely benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (51)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	28469040, 30054183, 30337194, 31539493		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	ORPHANET_DG	28469040		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Amyotrophic Lateral Sclerosis	Amyotrophic lateral sclerosis	Pubtator	28469040, 33610019, 35525134, 36134701, 36651622	Associate	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Amyotrophic lateral sclerosis	Amyotrophic Lateral Sclerosis	Orphanet			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	HPO_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
AMYOTROPHIC LATERAL SCLEROSIS 23	Amyotrophic lateral sclerosis	UNIPROT_DG	28469040		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AMYOTROPHIC LATERAL SCLEROSIS 23	Amyotrophic lateral sclerosis	GENOMICS_ENGLAND_DG	29845112		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AMYOTROPHIC LATERAL SCLEROSIS 23	Amyotrophic lateral sclerosis	CLINVAR_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Anxiety	Anxiety Disorder	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	Pubtator	35606283	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	19484149		★★★★★ ★☆☆☆☆ Found in Text Mining only
CATARACT, ANTERIOR POLAR	Cataract	BEFREE	29847180		★★★★★ ★☆☆☆☆ Found in Text Mining only
Celiac Disease	Celiac disease	BEFREE	23152861		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	GWASCAT_DG	23144326		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	29306955		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	23579219, 31308487	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	GWASDB_DG	23202125		★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	23152861		★★★★★ ★☆☆☆☆ Found in Text Mining only
Frontotemporal Dementia	Frontotemporal dementia	Pubtator	40713859	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Juvenile arthritis	Arthritis	BEFREE	23152861		★★★★★ ★☆☆☆☆ Found in Text Mining only
Laryngospasm	Laryngospasm	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	35463978	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	31088485		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	29306955	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	19484149		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	30160795		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	29306955		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mood swings	Mood swings	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy Oculopharyngeal	Oculopharyngeal muscular dystrophy	Pubtator	36651622	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27177629, 28594714, 29306955		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neural Tube Defects	Neural Tube Defect	BEFREE	15345369		★★★★★ ★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	19484149		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	19484149, 29306955	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	31474227	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	30160795		★★★★★ ★☆☆☆☆ Found in Text Mining only
Primary biliary cirrhosis	Biliary Cirrhosis	BEFREE	23152861		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pulmonary Fibrosis	Pulmonary Fibrosis	BEFREE	28079857		★★★★★ ★☆☆☆☆ Found in Text Mining only
Respiratory Failure	Respiratory Failure	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Sarcoidosis	Sarcoidosis	BEFREE	19165924, 21562576, 23151485, 23152861, 24032725, 25056970, 27071553, 27537711, 27662826, 28079857		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoidosis	Sarcoidosis	CTD_human_DG	19165924		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoidosis	Sarcoidosis	GWASDB_DG	19165924, 22936702		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoidosis	Sarcoidosis	Pubtator	20093723, 22952805, 23151485, 23152861, 25056970, 29416296	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoidosis	Sarcoidosis	GWASCAT_DG	22936702		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Secondary malignant neoplasm of colon and/or rectum	Colorectal Neoplasms	BEFREE	23579219, 27177629		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	29306955		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Diseases	Stomach disease	Pubtator	36356476	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	29306955	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	36356476	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uveitis	Uveitis	BEFREE	29416296		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uveitis	Uveitis	Pubtator	29416296	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ANXA11 (annexin A11)