Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	29980
Gene name	DNA replication fork stabilization factor DONSON
Gene symbol	DONSON
Synonyms (NCBI Gene)	B17C21orf60MIMISMISSLA
Chromosome	21
Chromosome location	21q22.11
Summary	This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown. [provided by RefSeq, Jul 2008]

Show/Hide all (13)

SNP ID	Visualize variation	Clinical significance	Consequence
rs146664036	T>C,G	Uncertain-significance, pathogenic, likely-pathogenic, benign	Missense variant, coding sequence variant
rs192585552	T>C	Pathogenic	Intron variant
rs534299298	C>A,T	Pathogenic	Splice donor variant
rs765112107	->A	Pathogenic	Stop gained, coding sequence variant
rs768071555	T>G	Pathogenic, uncertain-significance, benign	Missense variant, coding sequence variant
rs777061964	C>T	Pathogenic	Stop gained, coding sequence variant
rs779149681	T>C	Pathogenic	Intron variant
rs779803447	G>A,C	Pathogenic	Synonymous variant, missense variant, coding sequence variant
rs993687029	G>A	Pathogenic	Coding sequence variant, stop gained
rs1135401959	A>G	Pathogenic	Coding sequence variant, missense variant
rs1135401960	T>C	Pathogenic	Intron variant
rs1135401961	GAGTTA>-	Pathogenic	Coding sequence variant, inframe deletion
rs1569077147	GTGCT>-	Likely-pathogenic	Frameshift variant, coding sequence variant

406

Show/Hide all (406)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016303	hsa-miR-193b-3p	Microarray	20304954
MIRT028777	hsa-miR-26b-5p	Microarray	19088304
MIRT046340	hsa-miR-23b-3p	CLASH	23622248
MIRT606920	hsa-miR-8485	HITS-CLIP	19536157
MIRT539832	hsa-miR-329-3p	HITS-CLIP	19536157
MIRT539831	hsa-miR-362-3p	HITS-CLIP	19536157
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	19536157
MIRT606920	hsa-miR-8485	HITS-CLIP	19536157
MIRT539832	hsa-miR-329-3p	HITS-CLIP	19536157
MIRT539831	hsa-miR-362-3p	HITS-CLIP	19536157
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	19536157
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	21572407
MIRT606920	hsa-miR-8485	HITS-CLIP	22927820
MIRT539832	hsa-miR-329-3p	HITS-CLIP	22927820
MIRT539831	hsa-miR-362-3p	HITS-CLIP	22927820
MIRT607533	hsa-miR-603	HITS-CLIP	22927820
MIRT607532	hsa-miR-3941	HITS-CLIP	22927820
MIRT690539	hsa-miR-8084	HITS-CLIP	23313552
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23313552
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT607533	hsa-miR-603	HITS-CLIP	24906430
MIRT607532	hsa-miR-3941	HITS-CLIP	24906430
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT606920	hsa-miR-8485	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT539831	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	24906430
MIRT539832	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT539831	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT539829	hsa-miR-5195-5p	PAR-CLIP	21572407
MIRT539832	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT539831	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT539829	hsa-miR-5195-5p	PAR-CLIP	21572407
MIRT524020	hsa-miR-548n	PAR-CLIP	23446348
MIRT524019	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT524018	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT524017	hsa-miR-548at-5p	PAR-CLIP	23446348
MIRT524016	hsa-miR-1183	PAR-CLIP	23446348
MIRT524015	hsa-miR-4307	PAR-CLIP	23446348
MIRT524014	hsa-miR-20b-3p	PAR-CLIP	23446348
MIRT524013	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT524012	hsa-miR-5089-3p	PAR-CLIP	23446348
MIRT539832	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT539832	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT539832	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT539832	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT539832	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT539832	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT539831	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT539831	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT539831	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT539831	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT539831	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT539831	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT607532	hsa-miR-3941	HITS-CLIP	27418678
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	27418678
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	27418678
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	27418678
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	27418678
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	27418678
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	27418678
MIRT607533	hsa-miR-603	HITS-CLIP	27418678
MIRT690539	hsa-miR-8084	HITS-CLIP	27418678
MIRT574976	hsa-miR-8485	HITS-CLIP	27418678
MIRT574976	hsa-miR-8485	HITS-CLIP	27418678
MIRT574976	hsa-miR-8485	HITS-CLIP	27418678
MIRT574976	hsa-miR-8485	HITS-CLIP	27418678
MIRT574976	hsa-miR-8485	HITS-CLIP	27418678
MIRT574976	hsa-miR-8485	HITS-CLIP	27418678
MIRT539832	hsa-miR-329-3p	HITS-CLIP	28735896
MIRT539832	hsa-miR-329-3p	HITS-CLIP	28735896
MIRT539832	hsa-miR-329-3p	HITS-CLIP	28735896
MIRT539832	hsa-miR-329-3p	HITS-CLIP	28735896
MIRT539831	hsa-miR-362-3p	HITS-CLIP	28735896
MIRT539831	hsa-miR-362-3p	HITS-CLIP	28735896
MIRT539831	hsa-miR-362-3p	HITS-CLIP	28735896
MIRT539831	hsa-miR-362-3p	HITS-CLIP	28735896
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	28735896
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	28735896
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	28735896
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	28735896
MIRT574976	hsa-miR-8485	HITS-CLIP	28735896
MIRT574976	hsa-miR-8485	HITS-CLIP	28735896
MIRT574976	hsa-miR-8485	HITS-CLIP	28735896
MIRT574976	hsa-miR-8485	HITS-CLIP	28735896
MIRT737457	hsa-miR-101-5p	Luciferase reporter assayWestern blottingImmunohistochemistry (IHC)RNA-seqqRT-PCR	31975570
MIRT574976	hsa-miR-8485	HITS-CLIP	19536157
MIRT539832	hsa-miR-329-3p	HITS-CLIP	19536157
MIRT539831	hsa-miR-362-3p	HITS-CLIP	19536157
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	19536157
MIRT574976	hsa-miR-8485	HITS-CLIP	19536157
MIRT539832	hsa-miR-329-3p	HITS-CLIP	19536157
MIRT539831	hsa-miR-362-3p	HITS-CLIP	19536157
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	19536157
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	21572407
MIRT574976	hsa-miR-8485	HITS-CLIP	22927820
MIRT539832	hsa-miR-329-3p	HITS-CLIP	22927820
MIRT539831	hsa-miR-362-3p	HITS-CLIP	22927820
MIRT607533	hsa-miR-603	HITS-CLIP	22927820
MIRT607532	hsa-miR-3941	HITS-CLIP	22927820
MIRT690539	hsa-miR-8084	HITS-CLIP	23313552
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23313552
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT574976	hsa-miR-8485	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT539831	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT539829	hsa-miR-5195-5p	HITS-CLIP	23824327
MIRT539832	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT539831	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT539829	hsa-miR-5195-5p	PAR-CLIP	21572407
MIRT539832	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT539831	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT539829	hsa-miR-5195-5p	PAR-CLIP	21572407
MIRT524020	hsa-miR-548n	PAR-CLIP	23446348
MIRT524019	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT524018	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT524017	hsa-miR-548at-5p	PAR-CLIP	23446348
MIRT524016	hsa-miR-1183	PAR-CLIP	23446348
MIRT524015	hsa-miR-4307	PAR-CLIP	23446348
MIRT524014	hsa-miR-20b-3p	PAR-CLIP	23446348
MIRT524013	hsa-miR-340-5p	PAR-CLIP	23446348
MIRT524012	hsa-miR-5089-3p	PAR-CLIP	23446348
MIRT756202	hsa-miR-30a-3p	Luciferase reporter assayWestern blottingqRT-PCR	36345848
MIRT943368	hsa-miR-205	CLIP-seq
MIRT943369	hsa-miR-340	CLIP-seq
MIRT943370	hsa-miR-4659a-5p	CLIP-seq
MIRT943371	hsa-miR-4659b-5p	CLIP-seq
MIRT943372	hsa-miR-548t	CLIP-seq
MIRT1979332	hsa-miR-300	CLIP-seq
MIRT1979333	hsa-miR-381	CLIP-seq
MIRT1979334	hsa-miR-4328	CLIP-seq
MIRT1979335	hsa-miR-4501	CLIP-seq
MIRT1979336	hsa-miR-4666-3p	CLIP-seq
MIRT1979337	hsa-miR-4760-3p	CLIP-seq
MIRT1979338	hsa-miR-544	CLIP-seq
MIRT1979339	hsa-miR-767-3p	CLIP-seq
MIRT1979335	hsa-miR-4501	CLIP-seq
MIRT943370	hsa-miR-4659a-5p	CLIP-seq
MIRT943371	hsa-miR-4659b-5p	CLIP-seq
MIRT2518795	hsa-miR-129-5p	CLIP-seq
MIRT2518796	hsa-miR-146b-3p	CLIP-seq
MIRT2518797	hsa-miR-3157-3p	CLIP-seq
MIRT2518798	hsa-miR-3173-5p	CLIP-seq
MIRT1979335	hsa-miR-4501	CLIP-seq
MIRT2518799	hsa-miR-450b-5p	CLIP-seq
MIRT943370	hsa-miR-4659a-5p	CLIP-seq
MIRT943371	hsa-miR-4659b-5p	CLIP-seq
MIRT2518800	hsa-miR-4708-3p	CLIP-seq
MIRT2518801	hsa-miR-4803	CLIP-seq
MIRT2518802	hsa-miR-494	CLIP-seq
MIRT2518803	hsa-miR-548a-5p	CLIP-seq
MIRT2518804	hsa-miR-548ab	CLIP-seq
MIRT2518805	hsa-miR-548ak	CLIP-seq
MIRT2518806	hsa-miR-548b-3p	CLIP-seq
MIRT2518807	hsa-miR-548b-5p	CLIP-seq
MIRT2518808	hsa-miR-548c-5p	CLIP-seq
MIRT2518809	hsa-miR-548d-5p	CLIP-seq
MIRT2518810	hsa-miR-548h	CLIP-seq
MIRT2518811	hsa-miR-548i	CLIP-seq
MIRT2518812	hsa-miR-548j	CLIP-seq
MIRT2518813	hsa-miR-548k	CLIP-seq
MIRT2518814	hsa-miR-548l	CLIP-seq
MIRT2518815	hsa-miR-548w	CLIP-seq
MIRT2518816	hsa-miR-548y	CLIP-seq
MIRT2518817	hsa-miR-559	CLIP-seq
MIRT2518818	hsa-miR-802	CLIP-seq
MIRT2518819	hsa-miR-874	CLIP-seq
MIRT2518801	hsa-miR-4803	CLIP-seq
MIRT2518802	hsa-miR-494	CLIP-seq
MIRT2518803	hsa-miR-548a-5p	CLIP-seq
MIRT2518804	hsa-miR-548ab	CLIP-seq
MIRT2518805	hsa-miR-548ak	CLIP-seq
MIRT2518806	hsa-miR-548b-3p	CLIP-seq
MIRT2518807	hsa-miR-548b-5p	CLIP-seq
MIRT2518808	hsa-miR-548c-5p	CLIP-seq
MIRT2518809	hsa-miR-548d-5p	CLIP-seq
MIRT2518810	hsa-miR-548h	CLIP-seq
MIRT2518811	hsa-miR-548i	CLIP-seq
MIRT2518812	hsa-miR-548j	CLIP-seq
MIRT2518813	hsa-miR-548k	CLIP-seq
MIRT2518814	hsa-miR-548l	CLIP-seq
MIRT2518815	hsa-miR-548w	CLIP-seq
MIRT2518816	hsa-miR-548y	CLIP-seq
MIRT2518817	hsa-miR-559	CLIP-seq
MIRT2518818	hsa-miR-802	CLIP-seq

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000077	Process	DNA damage checkpoint signaling	IMP	28191891
GO:0005515	Function	Protein binding	IPI	28191891, 32769987
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	28191891
GO:0005634	Component	Nucleus	IEA
GO:0005657	Component	Replication fork	IDA	28191891
GO:0006260	Process	DNA replication	IMP	28191891
GO:0007095	Process	Mitotic G2 DNA damage checkpoint signaling	IMP	28191891
GO:0030894	Component	Replisome	IDA	28191891
GO:0031297	Process	Replication fork processing	IMP	28191891
GO:0033260	Process	Nuclear DNA replication	IBA
GO:0033314	Process	Mitotic DNA replication checkpoint signaling	IMP	28191891

MIM	HGNC	e!Ensembl
611428	2993	ENSG00000159147

Q9NYP3

Protein name

Protein downstream neighbor of Son (B17)

Protein function

Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in the brain, with higher levels in prenatal compared to adult brain. {ECO:0000269|PubMed:28630177}.

Sequence

MALSVPGYSPGFRKPPEVVRLRRKRARSRGAAASPPRELTEPAARRAALVAGLPLRPFPA
AGGRGGGSGGGPAAARRNPFARLDNRPRVAAEPPDGPAREQPEAPVPFLDSNQENDLLWE
EKFPERTTVTELPQTSHVSFSEPDIPSSKSTELPVDWSIKTRLLFTSSQPFTWADHLKAQ
EEAQGLVQHCRATEVTLPKSIQDPKLSSELRCTFQQSLIYWLHPALSWLPLFPRIGADRK
MAGKTSPWSNDATLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTVLFRAAGLAGS
DLITALISPTTRGLREAMRNEGIEFSLPLIKESGHKKETASGTSLGYGEEQAISDEDEEE
SFSWLEEMGVQDKIKKPDILSIKLRKEKHEVQMDHRPESVVLVKGINTFTLLNFLINSKS
LVATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRDQFSLEITGPIMPHS
LHSLTMLLKSSQSGSFSAVLYPHEPTAVFNICLQMDKVLDMEVVHKELTNCGLHPNTLEQ
LSQIPLLGKSSLRNVVLRDYIYNWRS

Sequence length

566

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (6)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
DONSON-related disorder	Pathogenic; Likely pathogenic	rs542296982, rs534299298, rs779149681	RCV003418422 RCV003899490 RCV003403146	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Meier-Gorlin syndrome	Pathogenic; Likely pathogenic	rs774616573, rs774052186, rs752810960, rs1010722195	RCV001527359 RCV001527358 RCV001527368 RCV001527367	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Meier-Gorlin syndrome 1	Likely pathogenic; Pathogenic	rs2145910302	RCV001533010	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Microcephaly, short stature, and limb abnormalities	Likely pathogenic; Pathogenic	rs1010722195, rs2517484685, rs2517474861, rs2517470416, rs779149681, rs1135401959, rs1135401961, rs993687029, rs779803447, rs777061964, rs765112107, rs534299298	RCV003314693 RCV003315110 RCV004018312 RCV004547213 RCV000496975 View all (7 more)	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Microcephaly-micromelia syndrome	Pathogenic; Likely pathogenic	rs779149681, rs993687029, rs534299298	RCV000496971 RCV001839008 RCV003989588	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Ovarian serous cystadenocarcinoma	Likely pathogenic	rs534299298	RCV005936772	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (13)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLORECTAL NEOPLASMS	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DESBUQUOIS SYNDROME	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DNA REPLICATION FORK STABILIZATION FACTOR DONSON-RELATED MICROCEPHALY, SHORT STATURE, LIMB ABNORMALITIES SPECTRUM	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DONSON-related Meier-Gorlin syndrome	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DWARFISM	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EAR, PATELLA, SHORT STATURE SYNDROME	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Microcephaly	Conflicting classifications of pathogenicity	ClinVar CTD, Disgenet CTD, Disgenet	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
MICROCEPHALY-SHORT STATURE-LIMB ABNORMALITIES SYNDROME	—	Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (53)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Anophthalmos with limb anomalies	Anophthalmia	Pubtator	31784481	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Brachydactyly	Brachydactyly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	39684297	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chromosomal Instability	Chromosomal instability	Pubtator	28191891	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Clinodactyly of the 5th finger	Camptodactyly of fingers	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	CTD_human_DG	25944804		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	CTD_human_DG	25944804		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Congenital clubfoot	Congenital Clubfoot	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital dislocation of radial head	Dislocated radial head	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital hypoplasia of lung	Pulmonary hypoplasia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital hypoplasia of radius	Congenital Hypoplasia Of Radius	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Craniosynostosis	Craniosynostosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down syndrome	Pubtator	28019128	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Dwarfism	Dwarfism	CTD_human_DG	28191891		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dwarfism	Dwarfism	BEFREE	31407851		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dwarfism	Dwarfism	Pubtator	31407851	Associate	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dwarfism	Dwarfism	HPO_DG			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Fanconi Anemia	Fanconi Anemia	BEFREE	29760432		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fanconi Anemia	Fanconi anemia	Pubtator	29760432	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)	Anemia	BEFREE	29760432		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	32016978	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Growth Disorders	Growth disorder	Pubtator	29760432, 31320746, 31407851, 31784481	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphangioma, Cystic	Cystic hygroma	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	32016978	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	30922402		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mesomelia	Mesomelia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	BEFREE	28191891, 31407851		★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Microcephaly	Microcephaly	CTD_human_DG	28191891		★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Microcephaly	Microcephaly	Pubtator	29760432, 31320746, 31407851, 31784481	Associate	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Microcephaly	Microcephaly	HPO_DG			★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
MICROCEPHALY, SHORT STATURE, AND LIMB ABNORMALITIES	Microcephaly-Short Stature-Limb Abnormalities Syndrome	UNIPROT_DG	28191891		★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
MICROCEPHALY, SHORT STATURE, AND LIMB ABNORMALITIES	Microcephaly-Short Stature-Limb Abnormalities Syndrome	GENOMICS_ENGLAND_DG	28191891, 28630177		★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
MICROCEPHALY, SHORT STATURE, AND LIMB ABNORMALITIES	Microcephaly-Short Stature-Limb Abnormalities Syndrome	BEFREE	31320746, 31407851		★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
MICROCEPHALY, SHORT STATURE, AND LIMB ABNORMALITIES	Microcephaly-Short Stature-Limb Abnormalities Syndrome	CLINVAR_DG			★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Microcephaly-Micromelia Syndrome	Microcephaly-Micromelia Syndrome	GENOMICS_ENGLAND_DG	28191891, 28630177		★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Microcephaly-micromelia syndrome	Microcephaly-Micromelia Syndrome	Orphanet			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Microcephaly-Micromelia Syndrome	Microcephaly-Micromelia Syndrome	CLINVAR_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Microcephaly-short stature-limb abnormalities syndrome	Microcephaly-Short Stature-Limb Abnormalities Syndrome	Orphanet			★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Micrognathism	Micrognathism	BEFREE	31407851		★★★★★ ★☆☆☆☆ Found in Text Mining only
Micrognathism	Micrognathism	Pubtator	31407851	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Micrognathism	Micrognathism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Microlissencephaly	Microlissencephaly	CTD_human_DG	28191891		★★★★★ ★☆☆☆☆ Found in Text Mining only
Micromelia	Micromelia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Microphthalmos	Microphthalmos	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Microstomia	Microstomia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Oligodactyly	Oligodactyly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	GWASCAT_DG	25854761		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Radioulnar Synostosis	Radioulnar Synostosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Ramer Ladda syndrome	Ramer Ladda Syndrome	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Seckel syndrome	Seckel Syndrome	BEFREE	29760432		★★★★★ ★☆☆☆☆ Found in Text Mining only
Seckel syndrome 1	Seckel syndrome	Pubtator	28191891, 29760432, 31407851	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Severe Congenital Microcephaly	Congenital Microcephaly	CTD_human_DG	28191891		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	30922402		★★★★★ ★☆☆☆☆ Found in Text Mining only

DONSON (DNA replication fork stabilization factor DONSON)