Gene Gene information from NCBI Gene database.
Entrez ID 29942
Gene name Purine rich element binding protein G
Gene symbol PURG
Synonyms (NCBI Gene)
PURG-APURG-BPURGAPURGB
Chromosome 8
Chromosome location 8p12
Summary The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PU
miRNA miRNA information provided by mirtarbase database.
376
miRTarBase ID miRNA Experiments Reference
MIRT020365 hsa-miR-29c-3p Sequencing 20371350
MIRT510901 hsa-miR-186-5p HITS-CLIP 21572407
MIRT506002 hsa-miR-6507-5p HITS-CLIP 21572407
MIRT510900 hsa-miR-1277-5p HITS-CLIP 21572407
MIRT521555 hsa-miR-4789-3p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
GO ID Ontology Definition Evidence Reference
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0003723 Function RNA binding HDA 22681889
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
618041 17930 ENSG00000172733
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UJV8
Protein name Purine-rich element-binding protein gamma (Purine-rich element-binding protein G)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04845 PurA 57 321 PurA ssDNA and RNA-binding protein Family
Tissue specificity TISSUE SPECIFICITY: Isoform 1 is expressed in testis and glioblastoma. Isoform 2 is expressed in fetal lung. {ECO:0000269|PubMed:12034829}.
Sequence
Sequence length 347
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
9
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ESSENTIAL HYPERTENSION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYPERTENSION GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Diabetes Mellitus, Non-Insulin-Dependent Diabetes Mellitus GWASCAT_DG 30054458
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of breast Breast Cancer UNIPROT_DG
★☆☆☆☆
Found in Text Mining only
Neoplasms Neoplasms BEFREE 12894583
★☆☆☆☆
Found in Text Mining only
Werner Syndrome Werner syndrome Pubtator 12034829 Associate
★★☆☆☆
Found in Text Mining + Unknown/Other Associations