HCFC2 (host cell factor C2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 29915 |
| Gene name | Host cell factor C2 |
| Gene symbol | HCFC2 |
| Synonyms (NCBI Gene) |
HCF-2HCF2
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| Chromosome | 12 |
| Chromosome location | 12q23.3 |
| Summary | This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The origin |
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miRNA
miRNA information provided by mirtarbase database.
520
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
28
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y5Z7 | |||||||||||||||
| Protein name | Host cell factor 2 (HCF-2) (C2 factor) | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in testis. Detected at lower levels in spleen, thymus, prostate, ovary, small intestine and colon. {ECO:0000269|PubMed:10196288}. | |||||||||||||||
| Sequence |
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| Sequence length | 792 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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