Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	29883
Gene name	CCR4-NOT transcription complex subunit 7
Gene symbol	CNOT7
Synonyms (NCBI Gene)	CAF-1CAF1Caf1ahCAF-1
Chromosome	8
Chromosome location	8p22
Summary	The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, caus

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miRTarBase ID	miRNA	Experiments	Reference
MIRT031760	hsa-miR-16-5p	Proteomics	18668040
MIRT044358	hsa-miR-106b-5p	CLASH	23622248
MIRT044358	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440918	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT044358	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727970	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727969	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727967	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727968	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT172594	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT172596	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT440918	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT900937	hsa-miR-106a	CLIP-seq
MIRT900938	hsa-miR-106b	CLIP-seq
MIRT900939	hsa-miR-1183	CLIP-seq
MIRT900940	hsa-miR-1200	CLIP-seq
MIRT900941	hsa-miR-1244	CLIP-seq
MIRT900942	hsa-miR-1263	CLIP-seq
MIRT900943	hsa-miR-1264	CLIP-seq
MIRT900944	hsa-miR-1270	CLIP-seq
MIRT900945	hsa-miR-1290	CLIP-seq
MIRT900946	hsa-miR-1303	CLIP-seq
MIRT900947	hsa-miR-130a	CLIP-seq
MIRT900948	hsa-miR-130b	CLIP-seq
MIRT900949	hsa-miR-1323	CLIP-seq
MIRT900950	hsa-miR-1343	CLIP-seq
MIRT900951	hsa-miR-148a	CLIP-seq
MIRT900952	hsa-miR-148b	CLIP-seq
MIRT900953	hsa-miR-152	CLIP-seq
MIRT900954	hsa-miR-17	CLIP-seq
MIRT900955	hsa-miR-185	CLIP-seq
MIRT900956	hsa-miR-1911	CLIP-seq
MIRT900957	hsa-miR-1976	CLIP-seq
MIRT900958	hsa-miR-199a-3p	CLIP-seq
MIRT900959	hsa-miR-199b-3p	CLIP-seq
MIRT900960	hsa-miR-19a	CLIP-seq
MIRT900961	hsa-miR-19b	CLIP-seq
MIRT900962	hsa-miR-2052	CLIP-seq
MIRT900963	hsa-miR-2054	CLIP-seq
MIRT900964	hsa-miR-20a	CLIP-seq
MIRT900965	hsa-miR-20b	CLIP-seq
MIRT900966	hsa-miR-2278	CLIP-seq
MIRT900967	hsa-miR-2681	CLIP-seq
MIRT900968	hsa-miR-298	CLIP-seq
MIRT900969	hsa-miR-301a	CLIP-seq
MIRT900970	hsa-miR-301b	CLIP-seq
MIRT900971	hsa-miR-3074-5p	CLIP-seq
MIRT900972	hsa-miR-30a	CLIP-seq
MIRT900973	hsa-miR-30b	CLIP-seq
MIRT900974	hsa-miR-30c	CLIP-seq
MIRT900975	hsa-miR-30d	CLIP-seq
MIRT900976	hsa-miR-30e	CLIP-seq
MIRT900977	hsa-miR-3120-3p	CLIP-seq
MIRT900978	hsa-miR-3121-3p	CLIP-seq
MIRT900979	hsa-miR-3129-5p	CLIP-seq
MIRT900980	hsa-miR-3130-5p	CLIP-seq
MIRT900981	hsa-miR-3137	CLIP-seq
MIRT900982	hsa-miR-3140-5p	CLIP-seq
MIRT900983	hsa-miR-3143	CLIP-seq
MIRT900984	hsa-miR-3144-3p	CLIP-seq
MIRT900985	hsa-miR-3148	CLIP-seq
MIRT900986	hsa-miR-3153	CLIP-seq
MIRT900987	hsa-miR-3156-5p	CLIP-seq
MIRT900988	hsa-miR-3158-5p	CLIP-seq
MIRT900989	hsa-miR-3163	CLIP-seq
MIRT900990	hsa-miR-3166	CLIP-seq
MIRT900991	hsa-miR-3179	CLIP-seq
MIRT900992	hsa-miR-3200-5p	CLIP-seq
MIRT900993	hsa-miR-3202	CLIP-seq
MIRT900994	hsa-miR-320a	CLIP-seq
MIRT900995	hsa-miR-320b	CLIP-seq
MIRT900996	hsa-miR-320c	CLIP-seq
MIRT900997	hsa-miR-320d	CLIP-seq
MIRT900998	hsa-miR-320e	CLIP-seq
MIRT900999	hsa-miR-3609	CLIP-seq
MIRT901000	hsa-miR-3613-3p	CLIP-seq
MIRT901001	hsa-miR-3616-5p	CLIP-seq
MIRT901002	hsa-miR-3647-3p	CLIP-seq
MIRT901003	hsa-miR-3647-5p	CLIP-seq
MIRT901004	hsa-miR-3655	CLIP-seq
MIRT901005	hsa-miR-3662	CLIP-seq
MIRT901006	hsa-miR-3666	CLIP-seq
MIRT901007	hsa-miR-3671	CLIP-seq
MIRT901008	hsa-miR-3685	CLIP-seq
MIRT901009	hsa-miR-3714	CLIP-seq
MIRT901010	hsa-miR-371-5p	CLIP-seq
MIRT901011	hsa-miR-371b-5p	CLIP-seq
MIRT901012	hsa-miR-375	CLIP-seq
MIRT901013	hsa-miR-3914	CLIP-seq
MIRT901014	hsa-miR-421	CLIP-seq
MIRT901015	hsa-miR-4251	CLIP-seq
MIRT901016	hsa-miR-4268	CLIP-seq
MIRT901017	hsa-miR-4272	CLIP-seq
MIRT901018	hsa-miR-4280	CLIP-seq
MIRT901019	hsa-miR-4295	CLIP-seq
MIRT901020	hsa-miR-4306	CLIP-seq
MIRT901021	hsa-miR-4307	CLIP-seq
MIRT901022	hsa-miR-4329	CLIP-seq
MIRT901023	hsa-miR-4429	CLIP-seq
MIRT901024	hsa-miR-4457	CLIP-seq
MIRT901025	hsa-miR-4477a	CLIP-seq
MIRT901026	hsa-miR-4482	CLIP-seq
MIRT901027	hsa-miR-4496	CLIP-seq
MIRT901028	hsa-miR-4509	CLIP-seq
MIRT901029	hsa-miR-4531	CLIP-seq
MIRT901030	hsa-miR-4533	CLIP-seq
MIRT901031	hsa-miR-454	CLIP-seq
MIRT901032	hsa-miR-4639-3p	CLIP-seq
MIRT901033	hsa-miR-4639-5p	CLIP-seq
MIRT901034	hsa-miR-4640-5p	CLIP-seq
MIRT901035	hsa-miR-4643	CLIP-seq
MIRT901036	hsa-miR-4644	CLIP-seq
MIRT901037	hsa-miR-466	CLIP-seq
MIRT901038	hsa-miR-4668-5p	CLIP-seq
MIRT901039	hsa-miR-4683	CLIP-seq
MIRT901040	hsa-miR-4695-3p	CLIP-seq
MIRT901041	hsa-miR-4697-3p	CLIP-seq
MIRT901042	hsa-miR-4704-3p	CLIP-seq
MIRT901043	hsa-miR-4705	CLIP-seq
MIRT901044	hsa-miR-4726-5p	CLIP-seq
MIRT901045	hsa-miR-4731-3p	CLIP-seq
MIRT901046	hsa-miR-4738-3p	CLIP-seq
MIRT901047	hsa-miR-4744	CLIP-seq
MIRT901048	hsa-miR-4756-3p	CLIP-seq
MIRT901049	hsa-miR-4775	CLIP-seq
MIRT901050	hsa-miR-4778-5p	CLIP-seq
MIRT901051	hsa-miR-4789-3p	CLIP-seq
MIRT901052	hsa-miR-4789-5p	CLIP-seq
MIRT901053	hsa-miR-4795-5p	CLIP-seq
MIRT901054	hsa-miR-4796-3p	CLIP-seq
MIRT901055	hsa-miR-4796-5p	CLIP-seq
MIRT901056	hsa-miR-4797-3p	CLIP-seq
MIRT901057	hsa-miR-4801	CLIP-seq
MIRT901058	hsa-miR-488	CLIP-seq
MIRT901059	hsa-miR-494	CLIP-seq
MIRT901060	hsa-miR-507	CLIP-seq
MIRT901061	hsa-miR-511	CLIP-seq
MIRT901062	hsa-miR-513b	CLIP-seq
MIRT901063	hsa-miR-518a-5p	CLIP-seq
MIRT901064	hsa-miR-519a	CLIP-seq
MIRT901065	hsa-miR-519b-3p	CLIP-seq
MIRT901066	hsa-miR-519c-3p	CLIP-seq
MIRT901067	hsa-miR-519d	CLIP-seq
MIRT901068	hsa-miR-526b	CLIP-seq
MIRT901069	hsa-miR-527	CLIP-seq
MIRT901070	hsa-miR-543	CLIP-seq
MIRT901071	hsa-miR-544	CLIP-seq
MIRT901072	hsa-miR-548a-3p	CLIP-seq
MIRT901073	hsa-miR-548aa	CLIP-seq
MIRT901074	hsa-miR-548ah	CLIP-seq
MIRT901075	hsa-miR-548an	CLIP-seq
MIRT901076	hsa-miR-548e	CLIP-seq
MIRT901077	hsa-miR-548f	CLIP-seq
MIRT901078	hsa-miR-548m	CLIP-seq
MIRT901079	hsa-miR-548o	CLIP-seq
MIRT901080	hsa-miR-548u	CLIP-seq
MIRT901081	hsa-miR-557	CLIP-seq
MIRT901082	hsa-miR-573	CLIP-seq
MIRT901083	hsa-miR-577	CLIP-seq
MIRT901084	hsa-miR-578	CLIP-seq
MIRT901085	hsa-miR-582-5p	CLIP-seq
MIRT901086	hsa-miR-620	CLIP-seq
MIRT901087	hsa-miR-625	CLIP-seq
MIRT901088	hsa-miR-639	CLIP-seq
MIRT901089	hsa-miR-651	CLIP-seq
MIRT901090	hsa-miR-875-5p	CLIP-seq
MIRT901091	hsa-miR-889	CLIP-seq
MIRT901092	hsa-miR-93	CLIP-seq
MIRT901093	hsa-miR-935	CLIP-seq
MIRT901094	hsa-miR-936	CLIP-seq
MIRT901095	hsa-miR-3173-3p	CLIP-seq
MIRT901008	hsa-miR-3685	CLIP-seq
MIRT901096	hsa-miR-384	CLIP-seq
MIRT901097	hsa-miR-4428	CLIP-seq
MIRT901098	hsa-miR-4477b	CLIP-seq
MIRT901099	hsa-miR-4517	CLIP-seq
MIRT901040	hsa-miR-4695-3p	CLIP-seq
MIRT901100	hsa-miR-4779	CLIP-seq
MIRT901101	hsa-miR-584	CLIP-seq
MIRT900941	hsa-miR-1244	CLIP-seq
MIRT900944	hsa-miR-1270	CLIP-seq
MIRT1967277	hsa-miR-128	CLIP-seq
MIRT900949	hsa-miR-1323	CLIP-seq
MIRT900950	hsa-miR-1343	CLIP-seq
MIRT900956	hsa-miR-1911	CLIP-seq
MIRT900958	hsa-miR-199a-3p	CLIP-seq
MIRT900959	hsa-miR-199b-3p	CLIP-seq
MIRT1967278	hsa-miR-200b	CLIP-seq
MIRT1967279	hsa-miR-200c	CLIP-seq
MIRT1967280	hsa-miR-218	CLIP-seq
MIRT1967281	hsa-miR-27a	CLIP-seq
MIRT1967282	hsa-miR-27b	CLIP-seq
MIRT1967283	hsa-miR-28-3p	CLIP-seq
MIRT900971	hsa-miR-3074-5p	CLIP-seq
MIRT1967284	hsa-miR-3117-5p	CLIP-seq
MIRT900979	hsa-miR-3129-5p	CLIP-seq
MIRT900983	hsa-miR-3143	CLIP-seq
MIRT900989	hsa-miR-3163	CLIP-seq
MIRT901007	hsa-miR-3671	CLIP-seq
MIRT1967285	hsa-miR-410	CLIP-seq
MIRT901016	hsa-miR-4268	CLIP-seq
MIRT1967286	hsa-miR-429	CLIP-seq
MIRT901029	hsa-miR-4531	CLIP-seq
MIRT901033	hsa-miR-4639-5p	CLIP-seq
MIRT901039	hsa-miR-4683	CLIP-seq
MIRT1967287	hsa-miR-4699-5p	CLIP-seq
MIRT1967288	hsa-miR-4704-5p	CLIP-seq
MIRT1967289	hsa-miR-4753-3p	CLIP-seq
MIRT901050	hsa-miR-4778-5p	CLIP-seq
MIRT901056	hsa-miR-4797-3p	CLIP-seq
MIRT901061	hsa-miR-511	CLIP-seq
MIRT1967290	hsa-miR-513a-5p	CLIP-seq
MIRT901070	hsa-miR-543	CLIP-seq
MIRT901073	hsa-miR-548aa	CLIP-seq
MIRT901079	hsa-miR-548o	CLIP-seq
MIRT1967291	hsa-miR-561	CLIP-seq
MIRT1967292	hsa-miR-576-3p	CLIP-seq
MIRT901086	hsa-miR-620	CLIP-seq
MIRT1967293	hsa-miR-636	CLIP-seq
MIRT1967294	hsa-miR-7	CLIP-seq
MIRT901093	hsa-miR-935	CLIP-seq
MIRT901094	hsa-miR-936	CLIP-seq
MIRT2202924	hsa-miR-127-5p	CLIP-seq
MIRT900946	hsa-miR-1303	CLIP-seq
MIRT900949	hsa-miR-1323	CLIP-seq
MIRT900951	hsa-miR-148a	CLIP-seq
MIRT900952	hsa-miR-148b	CLIP-seq
MIRT900953	hsa-miR-152	CLIP-seq
MIRT1967278	hsa-miR-200b	CLIP-seq
MIRT1967279	hsa-miR-200c	CLIP-seq
MIRT900963	hsa-miR-2054	CLIP-seq
MIRT1967280	hsa-miR-218	CLIP-seq
MIRT900966	hsa-miR-2278	CLIP-seq
MIRT1967283	hsa-miR-28-3p	CLIP-seq
MIRT900972	hsa-miR-30a	CLIP-seq
MIRT900973	hsa-miR-30b	CLIP-seq
MIRT900974	hsa-miR-30c	CLIP-seq
MIRT900975	hsa-miR-30d	CLIP-seq
MIRT900976	hsa-miR-30e	CLIP-seq
MIRT1967284	hsa-miR-3117-5p	CLIP-seq
MIRT900977	hsa-miR-3120-3p	CLIP-seq
MIRT900980	hsa-miR-3130-5p	CLIP-seq
MIRT2202925	hsa-miR-3132	CLIP-seq
MIRT900989	hsa-miR-3163	CLIP-seq
MIRT901002	hsa-miR-3647-3p	CLIP-seq
MIRT1967285	hsa-miR-410	CLIP-seq
MIRT901016	hsa-miR-4268	CLIP-seq
MIRT901017	hsa-miR-4272	CLIP-seq
MIRT1967286	hsa-miR-429	CLIP-seq
MIRT2202926	hsa-miR-4318	CLIP-seq
MIRT2202927	hsa-miR-4424	CLIP-seq
MIRT2202928	hsa-miR-4451	CLIP-seq
MIRT901026	hsa-miR-4482	CLIP-seq
MIRT901032	hsa-miR-4639-3p	CLIP-seq
MIRT901033	hsa-miR-4639-5p	CLIP-seq
MIRT901035	hsa-miR-4643	CLIP-seq
MIRT901037	hsa-miR-466	CLIP-seq
MIRT2202929	hsa-miR-4693-5p	CLIP-seq
MIRT901041	hsa-miR-4697-3p	CLIP-seq
MIRT2202930	hsa-miR-4699-3p	CLIP-seq
MIRT1967287	hsa-miR-4699-5p	CLIP-seq
MIRT901042	hsa-miR-4704-3p	CLIP-seq
MIRT1967288	hsa-miR-4704-5p	CLIP-seq
MIRT2202931	hsa-miR-4715-5p	CLIP-seq
MIRT901046	hsa-miR-4738-3p	CLIP-seq
MIRT1967289	hsa-miR-4753-3p	CLIP-seq
MIRT901049	hsa-miR-4775	CLIP-seq
MIRT2202932	hsa-miR-4786-3p	CLIP-seq
MIRT901051	hsa-miR-4789-3p	CLIP-seq
MIRT2202933	hsa-miR-520d-5p	CLIP-seq
MIRT2202934	hsa-miR-524-5p	CLIP-seq
MIRT901073	hsa-miR-548aa	CLIP-seq
MIRT901079	hsa-miR-548o	CLIP-seq
MIRT1967291	hsa-miR-561	CLIP-seq
MIRT2202935	hsa-miR-569	CLIP-seq
MIRT1967292	hsa-miR-576-3p	CLIP-seq
MIRT901085	hsa-miR-582-5p	CLIP-seq
MIRT1967293	hsa-miR-636	CLIP-seq
MIRT1967294	hsa-miR-7	CLIP-seq
MIRT901091	hsa-miR-889	CLIP-seq
MIRT2202936	hsa-miR-892a	CLIP-seq
MIRT901093	hsa-miR-935	CLIP-seq
MIRT2202925	hsa-miR-3132	CLIP-seq
MIRT2202927	hsa-miR-4424	CLIP-seq
MIRT2202928	hsa-miR-4451	CLIP-seq
MIRT2202935	hsa-miR-569	CLIP-seq
MIRT900941	hsa-miR-1244	CLIP-seq
MIRT900943	hsa-miR-1264	CLIP-seq
MIRT900944	hsa-miR-1270	CLIP-seq
MIRT900949	hsa-miR-1323	CLIP-seq
MIRT900958	hsa-miR-199a-3p	CLIP-seq
MIRT900959	hsa-miR-199b-3p	CLIP-seq
MIRT1967280	hsa-miR-218	CLIP-seq
MIRT1967283	hsa-miR-28-3p	CLIP-seq
MIRT2505777	hsa-miR-300	CLIP-seq
MIRT1967284	hsa-miR-3117-5p	CLIP-seq
MIRT900979	hsa-miR-3129-5p	CLIP-seq
MIRT2202925	hsa-miR-3132	CLIP-seq
MIRT900982	hsa-miR-3140-5p	CLIP-seq
MIRT900983	hsa-miR-3143	CLIP-seq
MIRT900986	hsa-miR-3153	CLIP-seq
MIRT900989	hsa-miR-3163	CLIP-seq
MIRT900990	hsa-miR-3166	CLIP-seq
MIRT2505778	hsa-miR-3194-3p	CLIP-seq
MIRT901001	hsa-miR-3616-5p	CLIP-seq
MIRT901003	hsa-miR-3647-5p	CLIP-seq
MIRT901004	hsa-miR-3655	CLIP-seq
MIRT901005	hsa-miR-3662	CLIP-seq
MIRT2505779	hsa-miR-3663-5p	CLIP-seq
MIRT901008	hsa-miR-3685	CLIP-seq
MIRT901009	hsa-miR-3714	CLIP-seq
MIRT901012	hsa-miR-375	CLIP-seq
MIRT2505780	hsa-miR-377	CLIP-seq
MIRT2505781	hsa-miR-381	CLIP-seq
MIRT2505782	hsa-miR-3926	CLIP-seq
MIRT901016	hsa-miR-4268	CLIP-seq
MIRT901017	hsa-miR-4272	CLIP-seq
MIRT901018	hsa-miR-4280	CLIP-seq
MIRT2202927	hsa-miR-4424	CLIP-seq
MIRT2202928	hsa-miR-4451	CLIP-seq
MIRT2505783	hsa-miR-4527	CLIP-seq
MIRT2505784	hsa-miR-4528	CLIP-seq
MIRT901029	hsa-miR-4531	CLIP-seq
MIRT901033	hsa-miR-4639-5p	CLIP-seq
MIRT901034	hsa-miR-4640-5p	CLIP-seq
MIRT901035	hsa-miR-4643	CLIP-seq
MIRT901037	hsa-miR-466	CLIP-seq
MIRT2505785	hsa-miR-4666-3p	CLIP-seq
MIRT901039	hsa-miR-4683	CLIP-seq
MIRT1967287	hsa-miR-4699-5p	CLIP-seq
MIRT1967288	hsa-miR-4704-5p	CLIP-seq
MIRT901044	hsa-miR-4726-5p	CLIP-seq
MIRT2505786	hsa-miR-4753-5p	CLIP-seq
MIRT901048	hsa-miR-4756-3p	CLIP-seq
MIRT901050	hsa-miR-4778-5p	CLIP-seq
MIRT901051	hsa-miR-4789-3p	CLIP-seq
MIRT901053	hsa-miR-4795-5p	CLIP-seq
MIRT901055	hsa-miR-4796-5p	CLIP-seq
MIRT901056	hsa-miR-4797-3p	CLIP-seq
MIRT901058	hsa-miR-488	CLIP-seq
MIRT2505787	hsa-miR-490-3p	CLIP-seq
MIRT901060	hsa-miR-507	CLIP-seq
MIRT901061	hsa-miR-511	CLIP-seq
MIRT901070	hsa-miR-543	CLIP-seq
MIRT901071	hsa-miR-544	CLIP-seq
MIRT901073	hsa-miR-548aa	CLIP-seq
MIRT901075	hsa-miR-548an	CLIP-seq
MIRT901078	hsa-miR-548m	CLIP-seq
MIRT901079	hsa-miR-548o	CLIP-seq
MIRT901081	hsa-miR-557	CLIP-seq
MIRT2202935	hsa-miR-569	CLIP-seq
MIRT901082	hsa-miR-573	CLIP-seq
MIRT1967292	hsa-miR-576-3p	CLIP-seq
MIRT901083	hsa-miR-577	CLIP-seq
MIRT901084	hsa-miR-578	CLIP-seq
MIRT901086	hsa-miR-620	CLIP-seq
MIRT901087	hsa-miR-625	CLIP-seq
MIRT1967293	hsa-miR-636	CLIP-seq
MIRT901088	hsa-miR-639	CLIP-seq
MIRT2505788	hsa-miR-649	CLIP-seq
MIRT2505789	hsa-miR-656	CLIP-seq
MIRT1967294	hsa-miR-7	CLIP-seq
MIRT901093	hsa-miR-935	CLIP-seq
MIRT901094	hsa-miR-936	CLIP-seq
MIRT900941	hsa-miR-1244	CLIP-seq
MIRT900943	hsa-miR-1264	CLIP-seq
MIRT900944	hsa-miR-1270	CLIP-seq
MIRT900958	hsa-miR-199a-3p	CLIP-seq
MIRT900959	hsa-miR-199b-3p	CLIP-seq
MIRT1967280	hsa-miR-218	CLIP-seq
MIRT1967283	hsa-miR-28-3p	CLIP-seq
MIRT1967284	hsa-miR-3117-5p	CLIP-seq
MIRT900979	hsa-miR-3129-5p	CLIP-seq
MIRT2202925	hsa-miR-3132	CLIP-seq
MIRT900983	hsa-miR-3143	CLIP-seq
MIRT900986	hsa-miR-3153	CLIP-seq
MIRT900989	hsa-miR-3163	CLIP-seq
MIRT900990	hsa-miR-3166	CLIP-seq
MIRT2505778	hsa-miR-3194-3p	CLIP-seq
MIRT901001	hsa-miR-3616-5p	CLIP-seq
MIRT901003	hsa-miR-3647-5p	CLIP-seq
MIRT901004	hsa-miR-3655	CLIP-seq
MIRT901005	hsa-miR-3662	CLIP-seq
MIRT2505779	hsa-miR-3663-5p	CLIP-seq
MIRT901008	hsa-miR-3685	CLIP-seq
MIRT901009	hsa-miR-3714	CLIP-seq
MIRT901012	hsa-miR-375	CLIP-seq
MIRT2505780	hsa-miR-377	CLIP-seq
MIRT2505782	hsa-miR-3926	CLIP-seq
MIRT901016	hsa-miR-4268	CLIP-seq
MIRT901017	hsa-miR-4272	CLIP-seq
MIRT901018	hsa-miR-4280	CLIP-seq
MIRT2202927	hsa-miR-4424	CLIP-seq
MIRT2202928	hsa-miR-4451	CLIP-seq
MIRT2505783	hsa-miR-4527	CLIP-seq
MIRT2505784	hsa-miR-4528	CLIP-seq
MIRT901029	hsa-miR-4531	CLIP-seq
MIRT901033	hsa-miR-4639-5p	CLIP-seq
MIRT901034	hsa-miR-4640-5p	CLIP-seq
MIRT901035	hsa-miR-4643	CLIP-seq
MIRT901037	hsa-miR-466	CLIP-seq
MIRT901039	hsa-miR-4683	CLIP-seq
MIRT1967287	hsa-miR-4699-5p	CLIP-seq
MIRT1967288	hsa-miR-4704-5p	CLIP-seq
MIRT901044	hsa-miR-4726-5p	CLIP-seq
MIRT2505786	hsa-miR-4753-5p	CLIP-seq
MIRT901048	hsa-miR-4756-3p	CLIP-seq
MIRT901050	hsa-miR-4778-5p	CLIP-seq
MIRT901051	hsa-miR-4789-3p	CLIP-seq
MIRT901053	hsa-miR-4795-5p	CLIP-seq
MIRT901055	hsa-miR-4796-5p	CLIP-seq
MIRT901056	hsa-miR-4797-3p	CLIP-seq
MIRT901058	hsa-miR-488	CLIP-seq
MIRT901060	hsa-miR-507	CLIP-seq
MIRT901061	hsa-miR-511	CLIP-seq
MIRT901070	hsa-miR-543	CLIP-seq
MIRT901071	hsa-miR-544	CLIP-seq
MIRT901075	hsa-miR-548an	CLIP-seq
MIRT901078	hsa-miR-548m	CLIP-seq
MIRT901081	hsa-miR-557	CLIP-seq
MIRT2202935	hsa-miR-569	CLIP-seq
MIRT901082	hsa-miR-573	CLIP-seq
MIRT1967292	hsa-miR-576-3p	CLIP-seq
MIRT901084	hsa-miR-578	CLIP-seq
MIRT901086	hsa-miR-620	CLIP-seq
MIRT901087	hsa-miR-625	CLIP-seq
MIRT1967293	hsa-miR-636	CLIP-seq
MIRT901088	hsa-miR-639	CLIP-seq
MIRT2505789	hsa-miR-656	CLIP-seq
MIRT1967294	hsa-miR-7	CLIP-seq
MIRT901093	hsa-miR-935	CLIP-seq
MIRT901094	hsa-miR-936	CLIP-seq

Show/Hide all (58)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000175	Function	3'-5'-RNA exonuclease activity	IDA	15769875
GO:0000288	Process	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IBA
GO:0000289	Process	Nuclear-transcribed mRNA poly(A) tail shortening	IDA	21336257
GO:0000289	Process	Nuclear-transcribed mRNA poly(A) tail shortening	IEA
GO:0000289	Process	Nuclear-transcribed mRNA poly(A) tail shortening	NAS	31320642
GO:0000290	Process	Deadenylation-dependent decapping of nuclear-transcribed mRNA	IDA	31439799
GO:0000290	Process	Deadenylation-dependent decapping of nuclear-transcribed mRNA	IEA
GO:0000932	Component	P-body	IBA
GO:0000932	Component	P-body	IEA
GO:0000932	Component	P-body	ISS
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003714	Function	Transcription corepressor activity	IMP	23386060
GO:0003723	Function	RNA binding	IEA
GO:0004518	Function	Nuclease activity	IEA
GO:0004527	Function	Exonuclease activity	IEA
GO:0004532	Function	RNA exonuclease activity	IDA	19276069
GO:0004535	Function	Poly(A)-specific ribonuclease activity	IBA
GO:0004535	Function	Poly(A)-specific ribonuclease activity	IDA	15769875, 19276069, 21336257, 31439799
GO:0004535	Function	Poly(A)-specific ribonuclease activity	IEA
GO:0005515	Function	Protein binding	IPI	9820826, 11136725, 11747467, 17452450, 18377426, 19276069, 19716330, 20584987, 20595389, 20595394, 21278420, 21336257, 21900206, 21981923, 21984185, 22977175, 25038453, 25106868, 25416956, 25959826, 26496610, 27107012, 28514442, 31515488, 32296183, 32502391, 32814053, 33961781
GO:0005634	Component	Nucleus	IDA	9820826
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	IMP	23386060
GO:0005829	Component	Cytosol	TAS
GO:0006417	Process	Regulation of translation	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	19605561
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	19276069
GO:0010629	Process	Negative regulation of gene expression	IMP	25038453
GO:0016020	Component	Membrane	HDA	19946888
GO:0016604	Component	Nuclear body	IDA
GO:0016607	Component	Nuclear speck	IMP	23386060
GO:0016787	Function	Hydrolase activity	IEA
GO:0030014	Component	CCR4-NOT complex	IDA	19558367, 21336257
GO:0030014	Component	CCR4-NOT complex	IEA
GO:0030014	Component	CCR4-NOT complex	NAS	9820826, 19558367
GO:0030015	Component	CCR4-NOT core complex	IBA
GO:0031047	Process	Regulatory ncRNA-mediated gene silencing	IEA
GO:0031047	Process	Regulatory ncRNA-mediated gene silencing	ISS
GO:0033962	Process	P-body assembly	IEA
GO:0034584	Function	PiRNA binding	IEA
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	20065043
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IEA
GO:0036464	Component	Cytoplasmic ribonucleoprotein granule	IEA
GO:0042509	Process	Regulation of tyrosine phosphorylation of STAT protein	IMP	23386060
GO:0045070	Process	Positive regulation of viral genome replication	IMP	23386060
GO:0045892	Process	Negative regulation of DNA-templated transcription	IMP	23386060
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051607	Process	Defense response to virus	IMP	23386060
GO:0060213	Process	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	IEA
GO:0060213	Process	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	IMP	21278420
GO:0060339	Process	Negative regulation of type I interferon-mediated signaling pathway	IMP	23386060
GO:0061014	Process	Positive regulation of mRNA catabolic process	IMP	23386060, 25038453
GO:0140297	Function	DNA-binding transcription factor binding	IPI	23386060
GO:0140991	Process	PiRNA-mediated gene silencing by mRNA destabilization	IEA
GO:1900153	Process	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IEA
GO:1900153	Process	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IMP	21278420

MIM	HGNC	e!Ensembl
604913	14101	ENSG00000198791

Q9UIV1

Protein name

CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)

Protein function

Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate (PubMed:19276069, PubMed:20634287, PubMed:31439799). Its function seems to be partially redundant with that of CNOT8 (PubMed:19605561). Catalytic component of the CCR

PDB

2D5R , 4GMJ , 7AX1 , 7VOI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04857	CAF1	15 → 139	CAF1 family ribonuclease	Family
PF04857	CAF1	133 → 238	CAF1 family ribonuclease	Family

Sequence

MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY
QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG
IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD
FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK
MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS

Sequence length

285

Interactions

View interactions

	KEGG		Reactome
	RNA degradation		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (27)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	29935546	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	33256566	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	32160402	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of larynx	Laryngeal carcinoma	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	26541675	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognition disorder	Pubtator	33757599	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	12845644		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	BEFREE	12845644		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cutaneous Melanoma	Melanoma	BEFREE	23109837		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	31797865	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down Syndrome	BEFREE	8660983		★★★★★ ★☆☆☆☆ Found in Text Mining only
Immune System Diseases	Immune system disease	Pubtator	23386060	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Laryngeal neoplasm	Laryngeal neoplasm	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Laryngeal Squamous Cell Carcinoma	Laryngeal Carcinoma	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	24836587, 28553742		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of larynx	Larynx cancer	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	21083601, 23109837		★★★★★ ★☆☆☆☆ Found in Text Mining only
Marinesco-Sjogren syndrome	Marinesco-Sjogren Syndrome	BEFREE	12845644		★★★★★ ★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy, Facioscapulohumeral	Facioscapulohumeral Muscular Dystrophy	BEFREE	29533181		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12845644, 21083601, 23109837, 26807845		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	17543081, 31627329		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of tongue	Tongue carcinoma	BEFREE	17543081		★★★★★ ★☆☆☆☆ Found in Text Mining only

CNOT7 (CCR4-NOT transcription complex subunit 7)