Gene Gene information from NCBI Gene database.
Entrez ID 286148
Gene name Dpy-19 like 4
Gene symbol DPY19L4
Synonyms (NCBI Gene)
-
Chromosome 8
Chromosome location 8q22.1
miRNA miRNA information provided by mirtarbase database.
719
miRTarBase ID miRNA Experiments Reference
MIRT050523 hsa-miR-20a-5p CLASH 23622248
MIRT048489 hsa-miR-100-5p CLASH 23622248
MIRT716641 hsa-miR-5680 HITS-CLIP 19536157
MIRT716640 hsa-miR-6515-3p HITS-CLIP 19536157
MIRT716639 hsa-miR-1236-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0000030 Function Mannosyltransferase activity IBA
GO:0005515 Function Protein binding IPI 28514442, 33961781
GO:0005789 Component Endoplasmic reticulum membrane IBA
GO:0016020 Component Membrane IEA
GO:0016740 Function Transferase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
613895 27829 ENSG00000156162
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z388
Protein name Probable C-mannosyltransferase DPY19L4 (EC 2.4.1.-) (Dpy-19-like protein 4) (Protein dpy-19 homolog 4)
Protein function Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10034 Dpy19 60 715 Q-cell neuroblast polarisation Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16526957}.
Sequence
Sequence length 723
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
7
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
GOUT GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HEART FAILURE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYPERTROPHIC CARDIOMYOPATHY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations