DTWD2 (DTW motif tRNA-uridine aminocarboxypropyltransferase 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 285605 |
| Gene name | DTW motif tRNA-uridine aminocarboxypropyltransferase 2 |
| Gene symbol | DTWD2 |
| Synonyms (NCBI Gene) |
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| Chromosome | 5 |
| Chromosome location | 5q23.1 |
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miRNA
miRNA information provided by mirtarbase database.
394
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8NBA8 | ||||||||||
| Protein name | tRNA-uridine aminocarboxypropyltransferase 2 (EC 2.5.1.25) (DTW domain-containing protein 2) | ||||||||||
| Protein function | Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20a in the D-loop of several cytoplasmic tRNAs (acp3U(20a)) (PubMed:31804502, PubMed:39173631). Also has a weak activity to form acp3U at position 20 in the D-loop | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 298 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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