Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	285527
Gene name	FRY like transcription coactivator
Gene symbol	FRYL
Synonyms (NCBI Gene)	AF4p12KIAA0826MOR2PCBS
Chromosome	4
Chromosome location	4p11

349

Show/Hide all (349)

miRTarBase ID	miRNA	Experiments	Reference
MIRT727647	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT727648	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT727646	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT727645	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT1005299	hsa-miR-103a	CLIP-seq
MIRT1005300	hsa-miR-107	CLIP-seq
MIRT1005301	hsa-miR-1179	CLIP-seq
MIRT1005302	hsa-miR-137	CLIP-seq
MIRT1005303	hsa-miR-146a	CLIP-seq
MIRT1005304	hsa-miR-146b-5p	CLIP-seq
MIRT1005305	hsa-miR-15a	CLIP-seq
MIRT1005306	hsa-miR-15b	CLIP-seq
MIRT1005307	hsa-miR-16	CLIP-seq
MIRT1005308	hsa-miR-181a	CLIP-seq
MIRT1005309	hsa-miR-181b	CLIP-seq
MIRT1005310	hsa-miR-181c	CLIP-seq
MIRT1005311	hsa-miR-181d	CLIP-seq
MIRT1005312	hsa-miR-195	CLIP-seq
MIRT1005313	hsa-miR-200b	CLIP-seq
MIRT1005314	hsa-miR-200c	CLIP-seq
MIRT1005315	hsa-miR-203	CLIP-seq
MIRT1005316	hsa-miR-2052	CLIP-seq
MIRT1005317	hsa-miR-25	CLIP-seq
MIRT1005318	hsa-miR-300	CLIP-seq
MIRT1005319	hsa-miR-3065-5p	CLIP-seq
MIRT1005320	hsa-miR-3140-3p	CLIP-seq
MIRT1005321	hsa-miR-3155	CLIP-seq
MIRT1005322	hsa-miR-3155b	CLIP-seq
MIRT1005323	hsa-miR-3163	CLIP-seq
MIRT1005324	hsa-miR-3199	CLIP-seq
MIRT1005325	hsa-miR-32	CLIP-seq
MIRT1005326	hsa-miR-323b-3p	CLIP-seq
MIRT1005327	hsa-miR-323b-5p	CLIP-seq
MIRT1005328	hsa-miR-326	CLIP-seq
MIRT1005329	hsa-miR-330-5p	CLIP-seq
MIRT1005330	hsa-miR-3612	CLIP-seq
MIRT1005331	hsa-miR-363	CLIP-seq
MIRT1005332	hsa-miR-367	CLIP-seq
MIRT1005333	hsa-miR-3671	CLIP-seq
MIRT1005334	hsa-miR-3675-3p	CLIP-seq
MIRT1005335	hsa-miR-3679-3p	CLIP-seq
MIRT1005336	hsa-miR-378	CLIP-seq
MIRT1005337	hsa-miR-378b	CLIP-seq
MIRT1005338	hsa-miR-378c	CLIP-seq
MIRT1005339	hsa-miR-378d	CLIP-seq
MIRT1005340	hsa-miR-378e	CLIP-seq
MIRT1005341	hsa-miR-378f	CLIP-seq
MIRT1005342	hsa-miR-378h	CLIP-seq
MIRT1005343	hsa-miR-378i	CLIP-seq
MIRT1005344	hsa-miR-381	CLIP-seq
MIRT1005345	hsa-miR-383	CLIP-seq
MIRT1005346	hsa-miR-3919	CLIP-seq
MIRT1005347	hsa-miR-3925-5p	CLIP-seq
MIRT1005348	hsa-miR-410	CLIP-seq
MIRT1005349	hsa-miR-422a	CLIP-seq
MIRT1005350	hsa-miR-424	CLIP-seq
MIRT1005351	hsa-miR-4262	CLIP-seq
MIRT1005352	hsa-miR-4265	CLIP-seq
MIRT1005353	hsa-miR-429	CLIP-seq
MIRT1005354	hsa-miR-4296	CLIP-seq
MIRT1005355	hsa-miR-4307	CLIP-seq
MIRT1005356	hsa-miR-4310	CLIP-seq
MIRT1005357	hsa-miR-432	CLIP-seq
MIRT1005358	hsa-miR-4322	CLIP-seq
MIRT1005359	hsa-miR-4433	CLIP-seq
MIRT1005360	hsa-miR-4443	CLIP-seq
MIRT1005361	hsa-miR-4459	CLIP-seq
MIRT1005362	hsa-miR-4468	CLIP-seq
MIRT1005363	hsa-miR-4474-5p	CLIP-seq
MIRT1005364	hsa-miR-4638-3p	CLIP-seq
MIRT1005365	hsa-miR-4648	CLIP-seq
MIRT1005366	hsa-miR-4654	CLIP-seq
MIRT1005367	hsa-miR-4756-3p	CLIP-seq
MIRT1005368	hsa-miR-4761-5p	CLIP-seq
MIRT1005369	hsa-miR-4762-5p	CLIP-seq
MIRT1005370	hsa-miR-4768-3p	CLIP-seq
MIRT1005371	hsa-miR-4769-5p	CLIP-seq
MIRT1005372	hsa-miR-4772-5p	CLIP-seq
MIRT1005373	hsa-miR-4795-3p	CLIP-seq
MIRT1005374	hsa-miR-4803	CLIP-seq
MIRT1005375	hsa-miR-484	CLIP-seq
MIRT1005376	hsa-miR-497	CLIP-seq
MIRT1005377	hsa-miR-516a-3p	CLIP-seq
MIRT1005378	hsa-miR-518a-5p	CLIP-seq
MIRT1005379	hsa-miR-527	CLIP-seq
MIRT1005380	hsa-miR-543	CLIP-seq
MIRT1005381	hsa-miR-579	CLIP-seq
MIRT1005382	hsa-miR-582-3p	CLIP-seq
MIRT1005383	hsa-miR-607	CLIP-seq
MIRT1005384	hsa-miR-622	CLIP-seq
MIRT1005385	hsa-miR-624	CLIP-seq
MIRT1005386	hsa-miR-642a	CLIP-seq
MIRT1005387	hsa-miR-650	CLIP-seq
MIRT1005388	hsa-miR-656	CLIP-seq
MIRT1005389	hsa-miR-659	CLIP-seq
MIRT1005390	hsa-miR-92a	CLIP-seq
MIRT1005391	hsa-miR-92b	CLIP-seq
MIRT1005302	hsa-miR-137	CLIP-seq
MIRT1005317	hsa-miR-25	CLIP-seq
MIRT1005325	hsa-miR-32	CLIP-seq
MIRT1005331	hsa-miR-363	CLIP-seq
MIRT1005332	hsa-miR-367	CLIP-seq
MIRT1548923	hsa-miR-3673	CLIP-seq
MIRT1005357	hsa-miR-432	CLIP-seq
MIRT1005378	hsa-miR-518a-5p	CLIP-seq
MIRT1005379	hsa-miR-527	CLIP-seq
MIRT1005380	hsa-miR-543	CLIP-seq
MIRT1005390	hsa-miR-92a	CLIP-seq
MIRT1005391	hsa-miR-92b	CLIP-seq
MIRT1997934	hsa-miR-1184	CLIP-seq
MIRT1997935	hsa-miR-1205	CLIP-seq
MIRT1997936	hsa-miR-1301	CLIP-seq
MIRT1005302	hsa-miR-137	CLIP-seq
MIRT1005317	hsa-miR-25	CLIP-seq
MIRT1005320	hsa-miR-3140-3p	CLIP-seq
MIRT1005321	hsa-miR-3155	CLIP-seq
MIRT1005322	hsa-miR-3155b	CLIP-seq
MIRT1997937	hsa-miR-3158-5p	CLIP-seq
MIRT1005325	hsa-miR-32	CLIP-seq
MIRT1005327	hsa-miR-323b-5p	CLIP-seq
MIRT1005330	hsa-miR-3612	CLIP-seq
MIRT1997938	hsa-miR-3622a-3p	CLIP-seq
MIRT1997939	hsa-miR-3622b-3p	CLIP-seq
MIRT1005331	hsa-miR-363	CLIP-seq
MIRT1997940	hsa-miR-3646	CLIP-seq
MIRT1997941	hsa-miR-3665	CLIP-seq
MIRT1005332	hsa-miR-367	CLIP-seq
MIRT1005335	hsa-miR-3679-3p	CLIP-seq
MIRT1997942	hsa-miR-4275	CLIP-seq
MIRT1005360	hsa-miR-4443	CLIP-seq
MIRT1997943	hsa-miR-4452	CLIP-seq
MIRT1997944	hsa-miR-4635	CLIP-seq
MIRT1997945	hsa-miR-4660	CLIP-seq
MIRT1005373	hsa-miR-4795-3p	CLIP-seq
MIRT1005375	hsa-miR-484	CLIP-seq
MIRT1997946	hsa-miR-5047	CLIP-seq
MIRT1997947	hsa-miR-5096	CLIP-seq
MIRT1005377	hsa-miR-516a-3p	CLIP-seq
MIRT1005378	hsa-miR-518a-5p	CLIP-seq
MIRT1997948	hsa-miR-526b	CLIP-seq
MIRT1005379	hsa-miR-527	CLIP-seq
MIRT1005380	hsa-miR-543	CLIP-seq
MIRT1997949	hsa-miR-578	CLIP-seq
MIRT1005381	hsa-miR-579	CLIP-seq
MIRT1005382	hsa-miR-582-3p	CLIP-seq
MIRT1997950	hsa-miR-593	CLIP-seq
MIRT1005384	hsa-miR-622	CLIP-seq
MIRT1005387	hsa-miR-650	CLIP-seq
MIRT1997951	hsa-miR-657	CLIP-seq
MIRT1005389	hsa-miR-659	CLIP-seq
MIRT1997952	hsa-miR-9	CLIP-seq
MIRT1005390	hsa-miR-92a	CLIP-seq
MIRT1005391	hsa-miR-92b	CLIP-seq
MIRT1005299	hsa-miR-103a	CLIP-seq
MIRT1005300	hsa-miR-107	CLIP-seq
MIRT1005301	hsa-miR-1179	CLIP-seq
MIRT1997934	hsa-miR-1184	CLIP-seq
MIRT1997935	hsa-miR-1205	CLIP-seq
MIRT2231526	hsa-miR-1299	CLIP-seq
MIRT1005303	hsa-miR-146a	CLIP-seq
MIRT1005304	hsa-miR-146b-5p	CLIP-seq
MIRT1005305	hsa-miR-15a	CLIP-seq
MIRT1005306	hsa-miR-15b	CLIP-seq
MIRT1005307	hsa-miR-16	CLIP-seq
MIRT1005312	hsa-miR-195	CLIP-seq
MIRT1997937	hsa-miR-3158-5p	CLIP-seq
MIRT1005326	hsa-miR-323b-3p	CLIP-seq
MIRT1997941	hsa-miR-3665	CLIP-seq
MIRT1005345	hsa-miR-383	CLIP-seq
MIRT1005346	hsa-miR-3919	CLIP-seq
MIRT1005347	hsa-miR-3925-5p	CLIP-seq
MIRT1005350	hsa-miR-424	CLIP-seq
MIRT1005356	hsa-miR-4310	CLIP-seq
MIRT1005362	hsa-miR-4468	CLIP-seq
MIRT1005367	hsa-miR-4756-3p	CLIP-seq
MIRT1005372	hsa-miR-4772-5p	CLIP-seq
MIRT1005373	hsa-miR-4795-3p	CLIP-seq
MIRT1005376	hsa-miR-497	CLIP-seq
MIRT1005381	hsa-miR-579	CLIP-seq
MIRT2231527	hsa-miR-582-5p	CLIP-seq
MIRT1997950	hsa-miR-593	CLIP-seq
MIRT1997951	hsa-miR-657	CLIP-seq
MIRT1005389	hsa-miR-659	CLIP-seq
MIRT2231528	hsa-miR-875-3p	CLIP-seq
MIRT1005389	hsa-miR-659	CLIP-seq
MIRT1005299	hsa-miR-103a	CLIP-seq
MIRT1005300	hsa-miR-107	CLIP-seq
MIRT1997934	hsa-miR-1184	CLIP-seq
MIRT2535423	hsa-miR-1193	CLIP-seq
MIRT1997935	hsa-miR-1205	CLIP-seq
MIRT2535424	hsa-miR-1206	CLIP-seq
MIRT2535425	hsa-miR-1255a	CLIP-seq
MIRT2535426	hsa-miR-1255b	CLIP-seq
MIRT2535427	hsa-miR-129-5p	CLIP-seq
MIRT2535428	hsa-miR-1305	CLIP-seq
MIRT2535429	hsa-miR-139-3p	CLIP-seq
MIRT2535430	hsa-miR-139-5p	CLIP-seq
MIRT2535431	hsa-miR-188-3p	CLIP-seq
MIRT1005316	hsa-miR-2052	CLIP-seq
MIRT2535432	hsa-miR-217	CLIP-seq
MIRT1005317	hsa-miR-25	CLIP-seq
MIRT2535433	hsa-miR-2909	CLIP-seq
MIRT1005319	hsa-miR-3065-5p	CLIP-seq
MIRT2535434	hsa-miR-3134	CLIP-seq
MIRT1005320	hsa-miR-3140-3p	CLIP-seq
MIRT1005321	hsa-miR-3155	CLIP-seq
MIRT1005322	hsa-miR-3155b	CLIP-seq
MIRT2535435	hsa-miR-3157-5p	CLIP-seq
MIRT1997937	hsa-miR-3158-5p	CLIP-seq
MIRT1005325	hsa-miR-32	CLIP-seq
MIRT2535436	hsa-miR-3200-3p	CLIP-seq
MIRT2535437	hsa-miR-3607-5p	CLIP-seq
MIRT2535438	hsa-miR-3613-3p	CLIP-seq
MIRT1997938	hsa-miR-3622a-3p	CLIP-seq
MIRT1997939	hsa-miR-3622b-3p	CLIP-seq
MIRT1005331	hsa-miR-363	CLIP-seq
MIRT1997941	hsa-miR-3665	CLIP-seq
MIRT1005332	hsa-miR-367	CLIP-seq
MIRT1005335	hsa-miR-3679-3p	CLIP-seq
MIRT2535439	hsa-miR-3691-5p	CLIP-seq
MIRT2535440	hsa-miR-377	CLIP-seq
MIRT2535441	hsa-miR-3943	CLIP-seq
MIRT2535442	hsa-miR-4263	CLIP-seq
MIRT1005355	hsa-miR-4307	CLIP-seq
MIRT2535443	hsa-miR-4323	CLIP-seq
MIRT2535444	hsa-miR-4464	CLIP-seq
MIRT1005363	hsa-miR-4474-5p	CLIP-seq
MIRT2535445	hsa-miR-4491	CLIP-seq
MIRT2535446	hsa-miR-4503	CLIP-seq
MIRT2535447	hsa-miR-450b-5p	CLIP-seq
MIRT2535448	hsa-miR-4514	CLIP-seq
MIRT2535449	hsa-miR-4657	CLIP-seq
MIRT2535450	hsa-miR-4684-5p	CLIP-seq
MIRT2535451	hsa-miR-4692	CLIP-seq
MIRT2535452	hsa-miR-4719	CLIP-seq
MIRT2535453	hsa-miR-4724-5p	CLIP-seq
MIRT2535454	hsa-miR-4726-3p	CLIP-seq
MIRT2535455	hsa-miR-4733-5p	CLIP-seq
MIRT2535456	hsa-miR-4748	CLIP-seq
MIRT2535457	hsa-miR-4752	CLIP-seq
MIRT2535458	hsa-miR-4789-3p	CLIP-seq
MIRT2535459	hsa-miR-4789-5p	CLIP-seq
MIRT2535460	hsa-miR-4802-5p	CLIP-seq
MIRT1005375	hsa-miR-484	CLIP-seq
MIRT2535461	hsa-miR-494	CLIP-seq
MIRT2535462	hsa-miR-507	CLIP-seq
MIRT1997947	hsa-miR-5096	CLIP-seq
MIRT1005377	hsa-miR-516a-3p	CLIP-seq
MIRT1005378	hsa-miR-518a-5p	CLIP-seq
MIRT1005379	hsa-miR-527	CLIP-seq
MIRT2535463	hsa-miR-548a-3p	CLIP-seq
MIRT2535464	hsa-miR-548ac	CLIP-seq
MIRT2535465	hsa-miR-548c-3p	CLIP-seq
MIRT2535466	hsa-miR-548d-3p	CLIP-seq
MIRT2535467	hsa-miR-548e	CLIP-seq
MIRT2535468	hsa-miR-548f	CLIP-seq
MIRT2535469	hsa-miR-548z	CLIP-seq
MIRT2535470	hsa-miR-557	CLIP-seq
MIRT2535471	hsa-miR-576-5p	CLIP-seq
MIRT1005381	hsa-miR-579	CLIP-seq
MIRT1005382	hsa-miR-582-3p	CLIP-seq
MIRT2231527	hsa-miR-582-5p	CLIP-seq
MIRT1997950	hsa-miR-593	CLIP-seq
MIRT1005384	hsa-miR-622	CLIP-seq
MIRT1997951	hsa-miR-657	CLIP-seq
MIRT1005389	hsa-miR-659	CLIP-seq
MIRT1997952	hsa-miR-9	CLIP-seq
MIRT2535472	hsa-miR-924	CLIP-seq
MIRT1005390	hsa-miR-92a	CLIP-seq
MIRT1005391	hsa-miR-92b	CLIP-seq
MIRT1005299	hsa-miR-103a	CLIP-seq
MIRT1005300	hsa-miR-107	CLIP-seq
MIRT1997934	hsa-miR-1184	CLIP-seq
MIRT2535423	hsa-miR-1193	CLIP-seq
MIRT1997935	hsa-miR-1205	CLIP-seq
MIRT2535424	hsa-miR-1206	CLIP-seq
MIRT2535425	hsa-miR-1255a	CLIP-seq
MIRT2535426	hsa-miR-1255b	CLIP-seq
MIRT2535427	hsa-miR-129-5p	CLIP-seq
MIRT2535430	hsa-miR-139-5p	CLIP-seq
MIRT2535431	hsa-miR-188-3p	CLIP-seq
MIRT1005316	hsa-miR-2052	CLIP-seq
MIRT2535432	hsa-miR-217	CLIP-seq
MIRT1005317	hsa-miR-25	CLIP-seq
MIRT2535433	hsa-miR-2909	CLIP-seq
MIRT1005319	hsa-miR-3065-5p	CLIP-seq
MIRT2535434	hsa-miR-3134	CLIP-seq
MIRT2681209	hsa-miR-3140-5p	CLIP-seq
MIRT1005321	hsa-miR-3155	CLIP-seq
MIRT1005322	hsa-miR-3155b	CLIP-seq
MIRT1997937	hsa-miR-3158-5p	CLIP-seq
MIRT1005325	hsa-miR-32	CLIP-seq
MIRT2535437	hsa-miR-3607-5p	CLIP-seq
MIRT2535438	hsa-miR-3613-3p	CLIP-seq
MIRT1997938	hsa-miR-3622a-3p	CLIP-seq
MIRT1997939	hsa-miR-3622b-3p	CLIP-seq
MIRT1005331	hsa-miR-363	CLIP-seq
MIRT1005332	hsa-miR-367	CLIP-seq
MIRT1005335	hsa-miR-3679-3p	CLIP-seq
MIRT2535439	hsa-miR-3691-5p	CLIP-seq
MIRT2535440	hsa-miR-377	CLIP-seq
MIRT2535441	hsa-miR-3943	CLIP-seq
MIRT2535442	hsa-miR-4263	CLIP-seq
MIRT1005355	hsa-miR-4307	CLIP-seq
MIRT2535443	hsa-miR-4323	CLIP-seq
MIRT2681210	hsa-miR-4422	CLIP-seq
MIRT2681211	hsa-miR-4427	CLIP-seq
MIRT1005363	hsa-miR-4474-5p	CLIP-seq
MIRT2535445	hsa-miR-4491	CLIP-seq
MIRT2535447	hsa-miR-450b-5p	CLIP-seq
MIRT2535448	hsa-miR-4514	CLIP-seq
MIRT2535449	hsa-miR-4657	CLIP-seq
MIRT2535450	hsa-miR-4684-5p	CLIP-seq
MIRT2535451	hsa-miR-4692	CLIP-seq
MIRT2535452	hsa-miR-4719	CLIP-seq
MIRT2535453	hsa-miR-4724-5p	CLIP-seq
MIRT2535454	hsa-miR-4726-3p	CLIP-seq
MIRT2535455	hsa-miR-4733-5p	CLIP-seq
MIRT2535457	hsa-miR-4752	CLIP-seq
MIRT2535458	hsa-miR-4789-3p	CLIP-seq
MIRT2535459	hsa-miR-4789-5p	CLIP-seq
MIRT2535460	hsa-miR-4802-5p	CLIP-seq
MIRT1005374	hsa-miR-4803	CLIP-seq
MIRT1005375	hsa-miR-484	CLIP-seq
MIRT2535462	hsa-miR-507	CLIP-seq
MIRT1997947	hsa-miR-5096	CLIP-seq
MIRT1005377	hsa-miR-516a-3p	CLIP-seq
MIRT1005378	hsa-miR-518a-5p	CLIP-seq
MIRT1005379	hsa-miR-527	CLIP-seq
MIRT2535463	hsa-miR-548a-3p	CLIP-seq
MIRT2535464	hsa-miR-548ac	CLIP-seq
MIRT2535465	hsa-miR-548c-3p	CLIP-seq
MIRT2535466	hsa-miR-548d-3p	CLIP-seq
MIRT2535467	hsa-miR-548e	CLIP-seq
MIRT2535468	hsa-miR-548f	CLIP-seq
MIRT2535469	hsa-miR-548z	CLIP-seq
MIRT2535470	hsa-miR-557	CLIP-seq
MIRT2535471	hsa-miR-576-5p	CLIP-seq
MIRT1005381	hsa-miR-579	CLIP-seq
MIRT2681212	hsa-miR-580	CLIP-seq
MIRT1005382	hsa-miR-582-3p	CLIP-seq
MIRT2231527	hsa-miR-582-5p	CLIP-seq
MIRT1997950	hsa-miR-593	CLIP-seq
MIRT1005384	hsa-miR-622	CLIP-seq
MIRT1005389	hsa-miR-659	CLIP-seq
MIRT1997952	hsa-miR-9	CLIP-seq
MIRT2535472	hsa-miR-924	CLIP-seq
MIRT1005390	hsa-miR-92a	CLIP-seq
MIRT1005391	hsa-miR-92b	CLIP-seq

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000902	Process	Cell morphogenesis	IBA
GO:0000902	Process	Cell morphogenesis	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 32296183, 33961781
GO:0005938	Component	Cell cortex	IBA
GO:0030427	Component	Site of polarized growth	IBA
GO:0031175	Process	Neuron projection development	IBA

MIM	HGNC	e!Ensembl
620798	29127	ENSG00000075539

O94915

Protein name

Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein)

Protein function

Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendri

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14222	MOR2-PAG1_N	117 → 649	Cell morphogenesis N-terminal	Family
PF14228	MOR2-PAG1_mid	1145 → 1329	Cell morphogenesis central region	Family
PF14228	MOR2-PAG1_mid	1350 → 1447	Cell morphogenesis central region	Family
PF14228	MOR2-PAG1_mid	1590 → 1663	Cell morphogenesis central region	Family
PF14228	MOR2-PAG1_mid	1724 → 1865	Cell morphogenesis central region	Family
PF14225	MOR2-PAG1_C	2001 → 2254	Cell morphogenesis C-terminal	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed with higher expression in colon, placenta, brain and cells of lymphoid origin. {ECO:0000269|PubMed:16061630}.

Sequence

MSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLI
SSMSSVAEHCLPSLLRTLFDWYRRQNGTEDESYEYRPRSSTKSKGDEQQRERDYLLERRD
LAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLY
AEVIGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFE
ASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTT
FELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLKNKDPKMSRVALESLY
RLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLD
FAMKEIIFDLLSVGKSTKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVILPSG
NTLRVKKIFLNKTLTDEEAKVIGMSVYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNK
EPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTL
QALMLDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVKMLVQLINQWKQAAQMHNKNQD
TQHGVANGASHPPPLERSPYSNVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALL
EIPKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLYCPSSIDLQTLAEWNSSPISHQF
DVISPSHIWIFAHVTQGQDPWIISLSSFLKQENLPKHCSTAVSYAWMFAYTRLQLLSPQV
DINSPINAKKVNTTTSSDSYIGLWRNYLILCCSAATSSSSTSAGSVRCSPPETLASTPDS
GYSIDSKIIGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIK
EALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHFLNNTLLEYVD
LTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHW
AGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNI
LDSLDKKVHQLGCEAVTLLLELNPDQSNLMYWAVDRCYTGSGRVAAGCFKAIANVFQNRD
YQCDTVMLLNLILFKAADSSRSIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLSQLSPL
PHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQVMLHYLLPWMNNIELVD
LKPLPTARRHDEDEDDSLKDRELMVTSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDEL
AWSEVENVWTTLADGWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLE
ELVSELQLTDPVSSGVTHMDNPPYYRITSSYKIPSVTSGTTSSSNTMVAPTDGNPDNKPI
KENIEESYVHLDIYSGLNSHLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVME
HNQGEPLPFPPAGGCWSPLVDYVPETSSPGLPLHRCNIAVILLTDLIIDHSVKVEWGSYL
HLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGPNSNIRTVASVLLRNKEFNEPRVLTV
KQVAHLDYNFTAGINDFIPDYQPSPMTDSGLSSSSTSSSISLGNNSAAISHLHTTILNEV
DISVEQDGKVKTLMEFITSRKRGPLWNHEDVSAKNPSIKSAEQLTTFLKHVVSVFKQSSS
EGIHLEHHLSEVALQTALSCSSRHYAGRSFQIFRALKQPLTATTLSDVLSRLVETVGDPG
EDAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSYHDPIMGNKYAANRKSTGQLNL
STSPINSSSYLGYNSNARSNSLRLSLIGDRRGDRRRSNTLDIMDGRINHSSSLARTRSLS
SLREKGMYDVQSTTEPTNLMATIFWIAASLLESDYEYEYLLALRLLNKLLIHLPLDKSES
REKIENVQSKLKWTNFPGLQQLFLKGFTSASTQEMTVHLLSKLISVSKHTLVDPSQLSGF
PLNILCLLPHLIQHFDSPTQFCKETASRIAKVCAEEKCPTLVNLAHMMSLYSTHTYSRDC
SNWINVVCRYLHDSFSDTTFNLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSAAPAK
QFNLEIIKIIGKYVQSPYWKEALNILKLVVSRSASLVVPSDIPKTYGGDTGSPEISFTKI
FNNVSKELPGKTLDFHFDISETPIIGNKYGDQHSAAGRNGKPKVIAVTRSTSSTSSGSNS
NALVPVSWKRPQLSQRRTREKLMNVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLIS
TTEDINQEEEVAVEDNSSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDK
GDTPSLQEYQCSSSTPSLNLTNQEDTDESSEEEAALTASQILSRTQMLNSDSATDETIPD
HPDLLLQSEDSTGSITTEEVLQIRDETPTLEASLDNANSRLPEDTTSVLKEEHVTTFEDE
GSYIIQEQQESLVCQGILDLEETEMPEPLAPESYPESVCEEDVTLALKELDERCEEEEAD
FSGLSSQDEEEQDGFPEVQTSPLPSPFLSAIIAAFQPVAYDDEEEAWRCHVNQMLSDTDG
SSAVFTFHVFSRLFQTIQRKFGEITNEAVSFLGDSLQRIGTKFKSSLEVMMLCSECPTVF
VDAETLMSCGLLETLKFGVLELQEHLDTYNVKREAAEQWLDDCKRTFGAKEDMYRINTDA
QQMEILAELELCRRLYKLHFQLLLLFQAYCKLINQVNTIKNEAEVINMSEELAQLESILK
EAESASENEEIDISKAAQTTIETAIHSLIETLKNKEFISAVAQVKAFRSLWPSDIFGSCE
DDPVQTLLHIYFHHQTLGQTGSFAVIGSNLDMSEANYKLMELNLEIRESLRMVQSYQLLA
QAKPMGNMVSTGF

Sequence length

3013

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
FRYL-related disorder	Likely pathogenic	rs2149264030	RCV001807976	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (21)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Acute myeloid leukemia	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COMPLEX NEURODEVELOPMENTAL DISORDER	—	GenCC	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FRYL-associated neurodevelopmental disorder	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FRYL-related developmental disorder	Uncertain significance; Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Pan-Chung-Bellen syndrome	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (7)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute leukemia	Leukemia	BEFREE	17854671	★★★★★ ★☆☆☆☆ Found in Text Mining only
Acute monocytic leukemia	Monocytic Leukemia	BEFREE	17854671	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	17854671	★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	LHGDN	17854671	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	17854671	★★★★★ ★☆☆☆☆ Found in Text Mining only
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	18195096	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	18195096	★★★★★ ★☆☆☆☆ Found in Text Mining only

FRYL (FRY like transcription coactivator)