Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	284904
Gene name	SEC14 like lipid binding 4
Gene symbol	SEC14L4
Synonyms (NCBI Gene)	TAP3
Chromosome	22
Chromosome location	22q12.2
Summary	The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thu

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016767	hsa-miR-335-5p	Microarray	18185580
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT662478	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT662477	hsa-miR-505-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT662476	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT644845	hsa-miR-548av-3p	HITS-CLIP	23824327
MIRT644844	hsa-miR-512-5p	HITS-CLIP	23824327
MIRT644843	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT644842	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT644841	hsa-miR-3692-5p	HITS-CLIP	23824327
MIRT644840	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT644839	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT644838	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT644837	hsa-miR-4731-5p	HITS-CLIP	23824327
MIRT644836	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT644835	hsa-miR-5089-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT644834	hsa-miR-2392	HITS-CLIP	23824327
MIRT644833	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT644832	hsa-miR-1193	HITS-CLIP	23824327
MIRT644831	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT644830	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT613756	hsa-miR-767-3p	HITS-CLIP	23824327
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT613756	hsa-miR-767-3p	HITS-CLIP	23824327
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT610171	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT610174	hsa-miR-153-5p	HITS-CLIP	27418678
MIRT610173	hsa-miR-192-3p	HITS-CLIP	27418678
MIRT610173	hsa-miR-192-3p	HITS-CLIP	27418678
MIRT610175	hsa-miR-4686	HITS-CLIP	27418678
MIRT610175	hsa-miR-4686	HITS-CLIP	27418678
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	27418678
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	27418678
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	27418678
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	27418678
MIRT613756	hsa-miR-767-3p	HITS-CLIP	27418678
MIRT613756	hsa-miR-767-3p	HITS-CLIP	27418678
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT662478	hsa-miR-432-5p	HITS-CLIP	23824327
MIRT662477	hsa-miR-505-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT662476	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT644845	hsa-miR-548av-3p	HITS-CLIP	23824327
MIRT644844	hsa-miR-512-5p	HITS-CLIP	23824327
MIRT644843	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT644842	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT644841	hsa-miR-3692-5p	HITS-CLIP	23824327
MIRT644840	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT644839	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT644838	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT644837	hsa-miR-4731-5p	HITS-CLIP	23824327
MIRT644836	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT644835	hsa-miR-5089-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT644834	hsa-miR-2392	HITS-CLIP	23824327
MIRT644833	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT644832	hsa-miR-1193	HITS-CLIP	23824327
MIRT644831	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT644830	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT613756	hsa-miR-767-3p	HITS-CLIP	23824327
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT613757	hsa-miR-4738-5p	HITS-CLIP	23824327
MIRT613756	hsa-miR-767-3p	HITS-CLIP	23824327
MIRT613755	hsa-miR-6828-3p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT610175	hsa-miR-4686	HITS-CLIP	23824327
MIRT610174	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT610173	hsa-miR-192-3p	HITS-CLIP	23824327
MIRT610172	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT610171	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT1332288	hsa-miR-125a-3p	CLIP-seq
MIRT1332289	hsa-miR-1266	CLIP-seq
MIRT1332290	hsa-miR-1913	CLIP-seq
MIRT1332291	hsa-miR-197	CLIP-seq
MIRT1332292	hsa-miR-324-3p	CLIP-seq
MIRT1332293	hsa-miR-3664-3p	CLIP-seq
MIRT1332294	hsa-miR-3914	CLIP-seq
MIRT1332295	hsa-miR-3934	CLIP-seq
MIRT1332296	hsa-miR-411	CLIP-seq
MIRT1332297	hsa-miR-4281	CLIP-seq
MIRT1332298	hsa-miR-4518	CLIP-seq
MIRT1332299	hsa-miR-4640-3p	CLIP-seq
MIRT1332300	hsa-miR-4716-5p	CLIP-seq
MIRT1332301	hsa-miR-5096	CLIP-seq
MIRT1332302	hsa-miR-764	CLIP-seq
MIRT1332303	hsa-miR-1227	CLIP-seq
MIRT1332288	hsa-miR-125a-3p	CLIP-seq
MIRT1332290	hsa-miR-1913	CLIP-seq
MIRT1332304	hsa-miR-3074-5p	CLIP-seq
MIRT1332305	hsa-miR-3187-3p	CLIP-seq
MIRT1332292	hsa-miR-324-3p	CLIP-seq
MIRT1332306	hsa-miR-370	CLIP-seq
MIRT1332307	hsa-miR-4252	CLIP-seq
MIRT1332308	hsa-miR-4435	CLIP-seq
MIRT1332309	hsa-miR-4701-5p	CLIP-seq
MIRT1332310	hsa-miR-4755-3p	CLIP-seq
MIRT1332311	hsa-miR-548s	CLIP-seq
MIRT1332312	hsa-miR-588	CLIP-seq
MIRT2098200	hsa-miR-1287	CLIP-seq
MIRT2098201	hsa-miR-149	CLIP-seq
MIRT2098202	hsa-miR-1825	CLIP-seq
MIRT1332291	hsa-miR-197	CLIP-seq
MIRT2098203	hsa-miR-2964a-5p	CLIP-seq
MIRT2098204	hsa-miR-3064-5p	CLIP-seq
MIRT2098205	hsa-miR-3194-3p	CLIP-seq
MIRT1332296	hsa-miR-411	CLIP-seq
MIRT2098206	hsa-miR-4294	CLIP-seq
MIRT2098207	hsa-miR-4679	CLIP-seq
MIRT1332300	hsa-miR-4716-5p	CLIP-seq
MIRT2098208	hsa-miR-4794	CLIP-seq
MIRT2098209	hsa-miR-5095	CLIP-seq
MIRT1332301	hsa-miR-5096	CLIP-seq
MIRT2098210	hsa-miR-552	CLIP-seq
MIRT2098211	hsa-miR-760	CLIP-seq
MIRT1332302	hsa-miR-764	CLIP-seq
MIRT2322927	hsa-miR-1200	CLIP-seq
MIRT2322928	hsa-miR-122	CLIP-seq
MIRT1332288	hsa-miR-125a-3p	CLIP-seq
MIRT2098201	hsa-miR-149	CLIP-seq
MIRT1332290	hsa-miR-1913	CLIP-seq
MIRT1332291	hsa-miR-197	CLIP-seq
MIRT2322929	hsa-miR-1976	CLIP-seq
MIRT2322930	hsa-miR-22	CLIP-seq
MIRT2098204	hsa-miR-3064-5p	CLIP-seq
MIRT2322931	hsa-miR-3149	CLIP-seq
MIRT1332292	hsa-miR-324-3p	CLIP-seq
MIRT2322932	hsa-miR-409-5p	CLIP-seq
MIRT1332296	hsa-miR-411	CLIP-seq
MIRT2322933	hsa-miR-4279	CLIP-seq
MIRT1332297	hsa-miR-4281	CLIP-seq
MIRT2322934	hsa-miR-4324	CLIP-seq
MIRT1332300	hsa-miR-4716-5p	CLIP-seq
MIRT2322935	hsa-miR-4722-3p	CLIP-seq
MIRT2322936	hsa-miR-4735-5p	CLIP-seq
MIRT2322937	hsa-miR-4775	CLIP-seq
MIRT2098208	hsa-miR-4794	CLIP-seq
MIRT2098209	hsa-miR-5095	CLIP-seq
MIRT1332301	hsa-miR-5096	CLIP-seq
MIRT2322938	hsa-miR-544b	CLIP-seq
MIRT2098210	hsa-miR-552	CLIP-seq
MIRT2322939	hsa-miR-590-3p	CLIP-seq
MIRT2322940	hsa-miR-660	CLIP-seq
MIRT2098211	hsa-miR-760	CLIP-seq
MIRT1332302	hsa-miR-764	CLIP-seq
MIRT2322928	hsa-miR-122	CLIP-seq
MIRT2098201	hsa-miR-149	CLIP-seq
MIRT1332291	hsa-miR-197	CLIP-seq
MIRT2098204	hsa-miR-3064-5p	CLIP-seq
MIRT2322931	hsa-miR-3149	CLIP-seq
MIRT1332296	hsa-miR-411	CLIP-seq
MIRT2098206	hsa-miR-4294	CLIP-seq
MIRT1332300	hsa-miR-4716-5p	CLIP-seq
MIRT2322936	hsa-miR-4735-5p	CLIP-seq
MIRT2322937	hsa-miR-4775	CLIP-seq
MIRT2098208	hsa-miR-4794	CLIP-seq
MIRT2098209	hsa-miR-5095	CLIP-seq
MIRT1332301	hsa-miR-5096	CLIP-seq
MIRT2098210	hsa-miR-552	CLIP-seq
MIRT2322939	hsa-miR-590-3p	CLIP-seq
MIRT2098211	hsa-miR-760	CLIP-seq
MIRT1332302	hsa-miR-764	CLIP-seq
MIRT1332291	hsa-miR-197	CLIP-seq
MIRT2322931	hsa-miR-3149	CLIP-seq
MIRT1332296	hsa-miR-411	CLIP-seq
MIRT1332300	hsa-miR-4716-5p	CLIP-seq
MIRT2322936	hsa-miR-4735-5p	CLIP-seq
MIRT2322937	hsa-miR-4775	CLIP-seq
MIRT2098209	hsa-miR-5095	CLIP-seq
MIRT1332301	hsa-miR-5096	CLIP-seq
MIRT2098210	hsa-miR-552	CLIP-seq
MIRT2322939	hsa-miR-590-3p	CLIP-seq
MIRT1332302	hsa-miR-764	CLIP-seq
MIRT2322927	hsa-miR-1200	CLIP-seq
MIRT2690315	hsa-miR-1225-5p	CLIP-seq
MIRT2690316	hsa-miR-1281	CLIP-seq
MIRT2690317	hsa-miR-1343	CLIP-seq
MIRT1332291	hsa-miR-197	CLIP-seq
MIRT2322929	hsa-miR-1976	CLIP-seq
MIRT2322931	hsa-miR-3149	CLIP-seq
MIRT1332296	hsa-miR-411	CLIP-seq
MIRT2322933	hsa-miR-4279	CLIP-seq
MIRT2322934	hsa-miR-4324	CLIP-seq
MIRT1332300	hsa-miR-4716-5p	CLIP-seq
MIRT2322935	hsa-miR-4722-3p	CLIP-seq
MIRT2322936	hsa-miR-4735-5p	CLIP-seq
MIRT2322937	hsa-miR-4775	CLIP-seq
MIRT2098209	hsa-miR-5095	CLIP-seq
MIRT1332301	hsa-miR-5096	CLIP-seq
MIRT2322938	hsa-miR-544b	CLIP-seq
MIRT2098210	hsa-miR-552	CLIP-seq
MIRT2322939	hsa-miR-590-3p	CLIP-seq
MIRT1332302	hsa-miR-764	CLIP-seq

Show/Hide all (3)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005737	Component	Cytoplasm	IBA
GO:0008289	Function	Lipid binding	IEA

MIM	HGNC	e!Ensembl
612825	20627	ENSG00000133488

Q9UDX3

Protein name

SEC14-like protein 4 (Tocopherol-associated protein 3)

Protein function

Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.

PDB

4TLG

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00650	CRAL_TRIO	79 → 244	CRAL/TRIO domain	Domain

Sequence

MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHM
EFRKQQDLDNIVTWQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDM
IRKRIKVCELLLHECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEA
NYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQLPVE
FGGTMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPG
CVLRWQFASDGGDIGFGVFLKTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGV
YVLRFDNTYSRMHAKKLSYTVEVLLPDKASEETLQSLKAMRPSPTQ

Sequence length

406

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (5)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Anemia	Anemia	Pubtator	34014839	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Anemia Sickle Cell	Sickle cell anemia	Pubtator	34014839	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Biliary Atresia	Biliary atresia	Pubtator	40665272	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hemolysis	Hemolysis	Pubtator	34014839	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	32066731	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

SEC14L4 (SEC14 like lipid binding 4)