ANKRD34A (ankyrin repeat domain 34A)

Gene

• Entrez ID: 284615
• Gene name: Ankyrin repeat domain 34A
• Gene symbol: ANKRD34A
• Synonyms (NCBI Gene): ANKRD34
• Chromosome: 1
• Chromosome location: 1q21.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT783582	hsa-miR-1224-3p	CLIP-seq
MIRT783583	hsa-miR-1260	CLIP-seq
MIRT783584	hsa-miR-1260b	CLIP-seq
MIRT783585	hsa-miR-1273g	CLIP-seq
MIRT783586	hsa-miR-1280	CLIP-seq
MIRT783587	hsa-miR-140-5p	CLIP-seq
MIRT783588	hsa-miR-150	CLIP-seq
MIRT783589	hsa-miR-15a	CLIP-seq
MIRT783590	hsa-miR-15b	CLIP-seq
MIRT783591	hsa-miR-16	CLIP-seq
MIRT783592	hsa-miR-195	CLIP-seq
MIRT783593	hsa-miR-2278	CLIP-seq
MIRT783594	hsa-miR-3170	CLIP-seq
MIRT783595	hsa-miR-424	CLIP-seq
MIRT783596	hsa-miR-4649-3p	CLIP-seq
MIRT783597	hsa-miR-4713-5p	CLIP-seq
MIRT783598	hsa-miR-4733-5p	CLIP-seq
MIRT783599	hsa-miR-4796-3p	CLIP-seq
MIRT783600	hsa-miR-497	CLIP-seq
MIRT783601	hsa-miR-532-3p	CLIP-seq
MIRT783602	hsa-miR-548t	CLIP-seq
MIRT783603	hsa-miR-548u	CLIP-seq
MIRT783604	hsa-miR-922	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0071546	Component	Pi-body	IBA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q69YU3
• Protein name: Ankyrin repeat domain-containing protein 34A
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12796	Ank_2	9 → 108	Ankyrin repeats (3 copies)	Repeat
  PF12796	Ank_2	53 → 141	Ankyrin repeats (3 copies)	Repeat

• Sequence:

  MLHTEGHALLRAVGQGKLRLARLLLEGGAYVNEGDAQGETALMAACRARYDDPQNKARMV
  RYLLEQGADPNIADRLGRTALMHACAGGGGAAVASLLLAHGADPSVRDHAGASALVHALD
  RGDRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYLNSPPSPGVEDPAPASPSPGF
  CTSPSEIQLQTAGGGGRGMLSPRAQEEEEKRDVFEFPLPKPPDDPSPSEPLPKPPRHPPK
  PLKRLNSEPWGLVAPPQPVPPTEGRPGIERLTAEFNGLTLTGRPRLSRRHSTEGPEDPPP
  WAEKVTSGGPLSRRNTAPEAQESGPPSGLRQKLSRMEPVELDTPGHLCPDSPESSRLSLE
  RRRYSASPLTLPPAGSAPSPRQSQESLPGAVSPLSGRRRSPGLLERRGSGTLLLDHISQT
  RPGFLPPLNVSPHPPIPDIRPQPGGRAPSLPAPPYAGAPGSPRTKRKLVRRHSMQTEQIR
  LLGGFQSLGGPGEPGR

• Sequence length: 496

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BREAST NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Breast Carcinoma	Breast Carcinoma	CTD_human_DG	29915430		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	CTD_human_DG	29915430		★☆☆☆☆ Found in Text Mining only
Mammary Carcinoma, Human	Marfan Syndrome	CTD_human_DG	29915430		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	CTD_human_DG	29915430		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms, Human	Mammary Neoplasms	CTD_human_DG	29915430		★☆☆☆☆ Found in Text Mining only