Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	27430
Gene name	Methionine adenosyltransferase 2 non-catalytic beta subunit
Gene symbol	MAT2B
Synonyms (NCBI Gene)	MAT-IIMATIIbetaNbla02999SDR23E1TGR
Chromosome	5
Chromosome location	5q34
Summary	The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results i

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Show/Hide all (304)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019945	hsa-miR-375	Microarray	20215506
MIRT020796	hsa-miR-155-5p	Proteomics	18668040
MIRT029818	hsa-miR-26b-5p	Microarray	19088304
MIRT032407	hsa-let-7b-5p	Proteomics	18668040
MIRT437430	hsa-miR-21-3p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	24098708
MIRT437430	hsa-miR-21-3p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	24098708
MIRT543363	hsa-miR-5692a	PAR-CLIP	21572407
MIRT543362	hsa-miR-377-3p	PAR-CLIP	21572407
MIRT543363	hsa-miR-5692a	PAR-CLIP	21572407
MIRT543362	hsa-miR-377-3p	PAR-CLIP	21572407
MIRT1133628	hsa-miR-1202	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT1133632	hsa-miR-203	CLIP-seq
MIRT1133633	hsa-miR-2116	CLIP-seq
MIRT1133634	hsa-miR-300	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133637	hsa-miR-3121-5p	CLIP-seq
MIRT1133638	hsa-miR-3194-5p	CLIP-seq
MIRT1133639	hsa-miR-323b-3p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT1133642	hsa-miR-3613-3p	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT1133644	hsa-miR-377	CLIP-seq
MIRT1133645	hsa-miR-381	CLIP-seq
MIRT1133646	hsa-miR-3972	CLIP-seq
MIRT1133647	hsa-miR-3974	CLIP-seq
MIRT1133648	hsa-miR-421	CLIP-seq
MIRT1133649	hsa-miR-4273	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT1133652	hsa-miR-4530	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133654	hsa-miR-4666-5p	CLIP-seq
MIRT1133655	hsa-miR-4668-3p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133657	hsa-miR-4677-5p	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133659	hsa-miR-4709-5p	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT1133662	hsa-miR-4795-3p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT1133664	hsa-miR-505	CLIP-seq
MIRT1133665	hsa-miR-513c	CLIP-seq
MIRT1133666	hsa-miR-514b-5p	CLIP-seq
MIRT1133667	hsa-miR-548a-3p	CLIP-seq
MIRT1133668	hsa-miR-548ac	CLIP-seq
MIRT1133669	hsa-miR-548ae	CLIP-seq
MIRT1133670	hsa-miR-548aj	CLIP-seq
MIRT1133671	hsa-miR-548am	CLIP-seq
MIRT1133672	hsa-miR-548c-3p	CLIP-seq
MIRT1133673	hsa-miR-548d-3p	CLIP-seq
MIRT1133674	hsa-miR-548e	CLIP-seq
MIRT1133675	hsa-miR-548f	CLIP-seq
MIRT1133676	hsa-miR-548g	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT1133678	hsa-miR-548x	CLIP-seq
MIRT1133679	hsa-miR-548z	CLIP-seq
MIRT1133680	hsa-miR-653	CLIP-seq
MIRT1133681	hsa-miR-656	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT1133685	hsa-miR-4253	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133689	hsa-miR-4761-3p	CLIP-seq
MIRT1133690	hsa-miR-4789-3p	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT1133692	hsa-miR-888	CLIP-seq
MIRT1133693	hsa-miR-938	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT2038022	hsa-miR-139-5p	CLIP-seq
MIRT2038023	hsa-miR-3120-3p	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT2038024	hsa-miR-3618	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT2038027	hsa-miR-3977	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT2038029	hsa-miR-4686	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT2038030	hsa-miR-4793-5p	CLIP-seq
MIRT1133662	hsa-miR-4795-3p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT2038031	hsa-miR-548a-5p	CLIP-seq
MIRT2038032	hsa-miR-548ab	CLIP-seq
MIRT2038033	hsa-miR-548ak	CLIP-seq
MIRT2038034	hsa-miR-548b-5p	CLIP-seq
MIRT2038035	hsa-miR-548c-5p	CLIP-seq
MIRT2038036	hsa-miR-548d-5p	CLIP-seq
MIRT2038037	hsa-miR-548h	CLIP-seq
MIRT2038038	hsa-miR-548i	CLIP-seq
MIRT2038039	hsa-miR-548j	CLIP-seq
MIRT2038040	hsa-miR-548k	CLIP-seq
MIRT2038041	hsa-miR-548l	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT2038042	hsa-miR-548w	CLIP-seq
MIRT2038043	hsa-miR-548y	CLIP-seq
MIRT2038044	hsa-miR-559	CLIP-seq
MIRT1133681	hsa-miR-656	CLIP-seq
MIRT2038045	hsa-miR-922	CLIP-seq
MIRT2267986	hsa-miR-106a	CLIP-seq
MIRT2267987	hsa-miR-106b	CLIP-seq
MIRT2267988	hsa-miR-1227	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT2038022	hsa-miR-139-5p	CLIP-seq
MIRT2267989	hsa-miR-17	CLIP-seq
MIRT2267990	hsa-miR-20a	CLIP-seq
MIRT2267991	hsa-miR-20b	CLIP-seq
MIRT1133633	hsa-miR-2116	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT2267992	hsa-miR-3064-3p	CLIP-seq
MIRT2038023	hsa-miR-3120-3p	CLIP-seq
MIRT2267993	hsa-miR-3140-5p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT1133641	hsa-miR-34c-3p	CLIP-seq
MIRT1133642	hsa-miR-3613-3p	CLIP-seq
MIRT2038024	hsa-miR-3618	CLIP-seq
MIRT2267994	hsa-miR-3647-3p	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT2267995	hsa-miR-3689d	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT1133644	hsa-miR-377	CLIP-seq
MIRT1133647	hsa-miR-3974	CLIP-seq
MIRT2038027	hsa-miR-3977	CLIP-seq
MIRT1133648	hsa-miR-421	CLIP-seq
MIRT1133649	hsa-miR-4273	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT1133651	hsa-miR-4321	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133655	hsa-miR-4668-3p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT1133657	hsa-miR-4677-5p	CLIP-seq
MIRT2038029	hsa-miR-4686	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT1133659	hsa-miR-4709-5p	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT1133690	hsa-miR-4789-3p	CLIP-seq
MIRT2038030	hsa-miR-4793-5p	CLIP-seq
MIRT1133662	hsa-miR-4795-3p	CLIP-seq
MIRT2267996	hsa-miR-4802-5p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT2267997	hsa-miR-496	CLIP-seq
MIRT1133664	hsa-miR-505	CLIP-seq
MIRT1133665	hsa-miR-513c	CLIP-seq
MIRT1133666	hsa-miR-514b-5p	CLIP-seq
MIRT2267998	hsa-miR-519d	CLIP-seq
MIRT1133667	hsa-miR-548a-3p	CLIP-seq
MIRT2038031	hsa-miR-548a-5p	CLIP-seq
MIRT2038032	hsa-miR-548ab	CLIP-seq
MIRT1133668	hsa-miR-548ac	CLIP-seq
MIRT1133669	hsa-miR-548ae	CLIP-seq
MIRT1133670	hsa-miR-548aj	CLIP-seq
MIRT2038033	hsa-miR-548ak	CLIP-seq
MIRT1133671	hsa-miR-548am	CLIP-seq
MIRT2038034	hsa-miR-548b-5p	CLIP-seq
MIRT1133672	hsa-miR-548c-3p	CLIP-seq
MIRT2038035	hsa-miR-548c-5p	CLIP-seq
MIRT1133673	hsa-miR-548d-3p	CLIP-seq
MIRT2038036	hsa-miR-548d-5p	CLIP-seq
MIRT1133674	hsa-miR-548e	CLIP-seq
MIRT1133675	hsa-miR-548f	CLIP-seq
MIRT1133676	hsa-miR-548g	CLIP-seq
MIRT2038037	hsa-miR-548h	CLIP-seq
MIRT2038038	hsa-miR-548i	CLIP-seq
MIRT2038039	hsa-miR-548j	CLIP-seq
MIRT2038040	hsa-miR-548k	CLIP-seq
MIRT2038041	hsa-miR-548l	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT2267999	hsa-miR-548t	CLIP-seq
MIRT2038042	hsa-miR-548w	CLIP-seq
MIRT1133678	hsa-miR-548x	CLIP-seq
MIRT2038043	hsa-miR-548y	CLIP-seq
MIRT1133679	hsa-miR-548z	CLIP-seq
MIRT2038044	hsa-miR-559	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT2038045	hsa-miR-922	CLIP-seq
MIRT2268000	hsa-miR-93	CLIP-seq
MIRT1133629	hsa-miR-130a	CLIP-seq
MIRT1133630	hsa-miR-130b	CLIP-seq
MIRT2431032	hsa-miR-142-5p	CLIP-seq
MIRT1133635	hsa-miR-301a	CLIP-seq
MIRT1133636	hsa-miR-301b	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT2431033	hsa-miR-3200-5p	CLIP-seq
MIRT2431034	hsa-miR-330-3p	CLIP-seq
MIRT1133640	hsa-miR-335	CLIP-seq
MIRT2431035	hsa-miR-3662	CLIP-seq
MIRT1133643	hsa-miR-3666	CLIP-seq
MIRT2431036	hsa-miR-3670	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT2431037	hsa-miR-4269	CLIP-seq
MIRT1133650	hsa-miR-4295	CLIP-seq
MIRT2431038	hsa-miR-4303	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT2431039	hsa-miR-4514	CLIP-seq
MIRT1133653	hsa-miR-454	CLIP-seq
MIRT2431040	hsa-miR-4659a-3p	CLIP-seq
MIRT2431041	hsa-miR-4659b-3p	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133656	hsa-miR-4671-3p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT2431042	hsa-miR-4692	CLIP-seq
MIRT1133658	hsa-miR-4696	CLIP-seq
MIRT2431043	hsa-miR-4698	CLIP-seq
MIRT1133660	hsa-miR-4729	CLIP-seq
MIRT2431044	hsa-miR-4742-5p	CLIP-seq
MIRT1133661	hsa-miR-4766-5p	CLIP-seq
MIRT2431045	hsa-miR-561	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT2438540	hsa-miR-4477b	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT1133631	hsa-miR-1323	CLIP-seq
MIRT1133633	hsa-miR-2116	CLIP-seq
MIRT2567689	hsa-miR-217	CLIP-seq
MIRT1133637	hsa-miR-3121-5p	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT2431035	hsa-miR-3662	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT1133685	hsa-miR-4253	CLIP-seq
MIRT1133649	hsa-miR-4273	CLIP-seq
MIRT2567690	hsa-miR-4418	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT2438540	hsa-miR-4477b	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT1133657	hsa-miR-4677-5p	CLIP-seq
MIRT2431043	hsa-miR-4698	CLIP-seq
MIRT2567691	hsa-miR-4699-3p	CLIP-seq
MIRT1133689	hsa-miR-4761-3p	CLIP-seq
MIRT1133663	hsa-miR-485-3p	CLIP-seq
MIRT2567692	hsa-miR-509-3-5p	CLIP-seq
MIRT2567693	hsa-miR-509-5p	CLIP-seq
MIRT1133677	hsa-miR-548o	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT1133692	hsa-miR-888	CLIP-seq
MIRT1133693	hsa-miR-938	CLIP-seq
MIRT2567689	hsa-miR-217	CLIP-seq
MIRT1133682	hsa-miR-3145-5p	CLIP-seq
MIRT2431035	hsa-miR-3662	CLIP-seq
MIRT2038025	hsa-miR-3671	CLIP-seq
MIRT1133683	hsa-miR-3691-3p	CLIP-seq
MIRT1133684	hsa-miR-371-5p	CLIP-seq
MIRT2038026	hsa-miR-371b-5p	CLIP-seq
MIRT1133685	hsa-miR-4253	CLIP-seq
MIRT2567690	hsa-miR-4418	CLIP-seq
MIRT1133686	hsa-miR-4436a	CLIP-seq
MIRT2438540	hsa-miR-4477b	CLIP-seq
MIRT2038028	hsa-miR-4522	CLIP-seq
MIRT1133687	hsa-miR-4662a-5p	CLIP-seq
MIRT1133688	hsa-miR-4676-5p	CLIP-seq
MIRT2431043	hsa-miR-4698	CLIP-seq
MIRT2567691	hsa-miR-4699-3p	CLIP-seq
MIRT1133689	hsa-miR-4761-3p	CLIP-seq
MIRT2567692	hsa-miR-509-3-5p	CLIP-seq
MIRT2567693	hsa-miR-509-5p	CLIP-seq
MIRT1133691	hsa-miR-575	CLIP-seq
MIRT1133692	hsa-miR-888	CLIP-seq
MIRT1133693	hsa-miR-938	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
SP1	Activation	11337507

Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25075345, 25416956, 32296183, 32353859, 33060197, 33961781, 36217030
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006556	Process	S-adenosylmethionine biosynthetic process	IBA
GO:0006556	Process	S-adenosylmethionine biosynthetic process	IDA	10644686, 25075345
GO:0006556	Process	S-adenosylmethionine biosynthetic process	IEA
GO:0006730	Process	One-carbon metabolic process	IEA
GO:0019899	Function	Enzyme binding	IPI	10644686
GO:0048269	Component	Methionine adenosyltransferase complex	IBA
GO:0048269	Component	Methionine adenosyltransferase complex	IDA	10644686, 25075345
GO:0048269	Component	Methionine adenosyltransferase complex	IPI	25075345
GO:0048270	Function	Methionine adenosyltransferase regulator activity	IBA
GO:0048270	Function	Methionine adenosyltransferase regulator activity	IDA	10644686, 25075345
GO:0070062	Component	Extracellular exosome	HDA	23533145

MIM	HGNC	e!Ensembl
605527	6905	ENSG00000038274

Q9NZL9

Protein name

Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase)

Protein function

Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L

PDB

2YDX , 2YDY , 4KTT , 4KTV , 4NDN

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04321	RmlD_sub_bind	29 → 324	RmlD substrate binding domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10644686, ECO:0000269|PubMed:11337507}.

Sequence

MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF
RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL
AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL
RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML
DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL
ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH

Sequence length

334

Interactions

View interactions

	KEGG		Reactome
	Cysteine and methionine metabolism One carbon pool by folate Metabolic pathways Biosynthesis of amino acids Biosynthesis of cofactors		Methylation Ub-specific processing proteases

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OROPHARYNX CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (40)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Agenesis of corpus callosum	Agenesis Of Corpus Callosum	BEFREE	28377480		★★★★★ ★☆☆☆☆ Found in Text Mining only
Aplasia Cutis Congenita	Aplasia Cutis Congenita	BEFREE	28377480		★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	30069364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	38116315	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	18045590, 20421296, 23814050, 24098708, 25794709	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	BEFREE	9717050		★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	30069364		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	29108270		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	23325601, 25794709	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congestive heart failure	Congestive Heart Failure	BEFREE	28475616		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	12206992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	12206992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Cardiomyopathies	Diabetic cardiomyopathy	BEFREE	12206992		★★★★★ ★☆☆☆☆ Found in Text Mining only
Fibrosis, Liver	Liver Fibrosis	BEFREE	31406138		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulosclerosis (disorder)	Glomerulosclerosis	BEFREE	17726104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart failure	Heart Failure	BEFREE	28475616		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	26873967, 28353076, 30054426, 31629566, 31786987, 31790054, 7699997		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperthyroidism	Hyperthyroidism	BEFREE	29685981		★★★★★ ★☆☆☆☆ Found in Text Mining only
Left Ventricular Hypertrophy	Left Ventricular Hypertrophy	BEFREE	11518854		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leiomyoma	Leiomyoma	Pubtator	30196971	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	12671891, 24098708, 29150921, 31004447, 31493275		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	18045590		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure	Liver failure	Pubtator	25794709	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	12671891		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	LHGDN	18041713, 18698677		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Hypertension	Malignant Hypertension	BEFREE	20724906, 9797175		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	31493275		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	29108270		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29108270, 31004447		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	27573889		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	17022964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27573889, 29141455, 30942439, 31354356		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	9515567		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	31406138		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	29430615		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	30942439		★★★★★ ★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	BEFREE	16824773		★★★★★ ★☆☆☆☆ Found in Text Mining only
Portal Hypertension	Portal Hypertension	BEFREE	31406138		★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple Negative Breast Neoplasms	BEFREE	31354356		★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	25921176	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

MAT2B (methionine adenosyltransferase 2 non-catalytic beta subunit)