Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	27333
Gene name	Golgi integral membrane protein 4
Gene symbol	GOLIM4
Synonyms (NCBI Gene)	GIMPCGOLPH4GPP130P138
Chromosome	3
Chromosome location	3q26.2
Summary	The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi-resident protein. It may process proteins synthesized in the rough endoplasmic reti

160

Show/Hide all (160)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049004	hsa-miR-92a-3p	CLASH	23622248
MIRT048034	hsa-miR-148a-3p	CLASH	23622248
MIRT045671	hsa-miR-149-5p	CLASH	23622248
MIRT643154	hsa-miR-10a-3p	HITS-CLIP	23824327
MIRT643153	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT643152	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT643151	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT643150	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT643149	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT548052	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT548051	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT548050	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT548049	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT548048	hsa-miR-646	PAR-CLIP	21572407
MIRT548047	hsa-miR-1910-3p	PAR-CLIP	21572407
MIRT548046	hsa-miR-6511a-5p	PAR-CLIP	21572407
MIRT548044	hsa-miR-6808-5p	PAR-CLIP	21572407
MIRT548045	hsa-miR-6893-5p	PAR-CLIP	21572407
MIRT548043	hsa-miR-940	PAR-CLIP	21572407
MIRT548042	hsa-miR-2682-5p	PAR-CLIP	21572407
MIRT548041	hsa-miR-34b-5p	PAR-CLIP	21572407
MIRT548040	hsa-miR-449c-5p	PAR-CLIP	21572407
MIRT548039	hsa-miR-5000-5p	PAR-CLIP	21572407
MIRT548038	hsa-miR-936	PAR-CLIP	21572407
MIRT548036	hsa-miR-4468	PAR-CLIP	21572407
MIRT548037	hsa-miR-6806-5p	PAR-CLIP	21572407
MIRT548034	hsa-miR-8055	PAR-CLIP	21572407
MIRT548035	hsa-miR-105-3p	PAR-CLIP	21572407
MIRT548052	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT548051	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT548050	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT548049	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT548048	hsa-miR-646	PAR-CLIP	21572407
MIRT548047	hsa-miR-1910-3p	PAR-CLIP	21572407
MIRT548046	hsa-miR-6511a-5p	PAR-CLIP	21572407
MIRT548044	hsa-miR-6808-5p	PAR-CLIP	21572407
MIRT548045	hsa-miR-6893-5p	PAR-CLIP	21572407
MIRT548043	hsa-miR-940	PAR-CLIP	21572407
MIRT548042	hsa-miR-2682-5p	PAR-CLIP	21572407
MIRT548041	hsa-miR-34b-5p	PAR-CLIP	21572407
MIRT548040	hsa-miR-449c-5p	PAR-CLIP	21572407
MIRT548039	hsa-miR-5000-5p	PAR-CLIP	21572407
MIRT548038	hsa-miR-936	PAR-CLIP	21572407
MIRT548036	hsa-miR-4468	PAR-CLIP	21572407
MIRT548037	hsa-miR-6806-5p	PAR-CLIP	21572407
MIRT526478	hsa-miR-222-5p	PAR-CLIP	21572407
MIRT548034	hsa-miR-8055	PAR-CLIP	21572407
MIRT548035	hsa-miR-105-3p	PAR-CLIP	21572407
MIRT548032	hsa-miR-4282	PAR-CLIP	21572407
MIRT548033	hsa-miR-3163	PAR-CLIP	21572407
MIRT548031	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT548030	hsa-miR-3659	PAR-CLIP	21572407
MIRT548029	hsa-miR-203a-5p	PAR-CLIP	21572407
MIRT548028	hsa-miR-1273g-5p	PAR-CLIP	21572407
MIRT548027	hsa-miR-4477a	PAR-CLIP	21572407
MIRT548025	hsa-miR-4658	PAR-CLIP	21572407
MIRT548026	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT548024	hsa-miR-487a-5p	PAR-CLIP	21572407
MIRT548023	hsa-miR-487b-5p	PAR-CLIP	21572407
MIRT526480	hsa-miR-16-1-3p	PAR-CLIP	22012620
MIRT526479	hsa-miR-556-3p	PAR-CLIP	22012620
MIRT526478	hsa-miR-222-5p	PAR-CLIP	22012620
MIRT526477	hsa-miR-30a-3p	PAR-CLIP	22012620
MIRT526476	hsa-miR-30d-3p	PAR-CLIP	22012620
MIRT526475	hsa-miR-30e-3p	PAR-CLIP	22012620
MIRT643154	hsa-miR-10a-3p	HITS-CLIP	23824327
MIRT643153	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT643152	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT643151	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT643150	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT643149	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT548052	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT548051	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT548050	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT548049	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT548048	hsa-miR-646	PAR-CLIP	21572407
MIRT548047	hsa-miR-1910-3p	PAR-CLIP	21572407
MIRT548046	hsa-miR-6511a-5p	PAR-CLIP	21572407
MIRT548044	hsa-miR-6808-5p	PAR-CLIP	21572407
MIRT548045	hsa-miR-6893-5p	PAR-CLIP	21572407
MIRT548043	hsa-miR-940	PAR-CLIP	21572407
MIRT548042	hsa-miR-2682-5p	PAR-CLIP	21572407
MIRT548041	hsa-miR-34b-5p	PAR-CLIP	21572407
MIRT548040	hsa-miR-449c-5p	PAR-CLIP	21572407
MIRT548039	hsa-miR-5000-5p	PAR-CLIP	21572407
MIRT548038	hsa-miR-936	PAR-CLIP	21572407
MIRT548036	hsa-miR-4468	PAR-CLIP	21572407
MIRT548037	hsa-miR-6806-5p	PAR-CLIP	21572407
MIRT548034	hsa-miR-8055	PAR-CLIP	21572407
MIRT548035	hsa-miR-105-3p	PAR-CLIP	21572407
MIRT548052	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT548051	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT548050	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT548049	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT548048	hsa-miR-646	PAR-CLIP	21572407
MIRT548047	hsa-miR-1910-3p	PAR-CLIP	21572407
MIRT548046	hsa-miR-6511a-5p	PAR-CLIP	21572407
MIRT548044	hsa-miR-6808-5p	PAR-CLIP	21572407
MIRT548045	hsa-miR-6893-5p	PAR-CLIP	21572407
MIRT548043	hsa-miR-940	PAR-CLIP	21572407
MIRT548042	hsa-miR-2682-5p	PAR-CLIP	21572407
MIRT548041	hsa-miR-34b-5p	PAR-CLIP	21572407
MIRT548040	hsa-miR-449c-5p	PAR-CLIP	21572407
MIRT548039	hsa-miR-5000-5p	PAR-CLIP	21572407
MIRT548038	hsa-miR-936	PAR-CLIP	21572407
MIRT548036	hsa-miR-4468	PAR-CLIP	21572407
MIRT548037	hsa-miR-6806-5p	PAR-CLIP	21572407
MIRT526478	hsa-miR-222-5p	PAR-CLIP	21572407
MIRT548034	hsa-miR-8055	PAR-CLIP	21572407
MIRT548035	hsa-miR-105-3p	PAR-CLIP	21572407
MIRT548032	hsa-miR-4282	PAR-CLIP	21572407
MIRT548033	hsa-miR-3163	PAR-CLIP	21572407
MIRT548031	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT548030	hsa-miR-3659	PAR-CLIP	21572407
MIRT548029	hsa-miR-203a-5p	PAR-CLIP	21572407
MIRT548028	hsa-miR-1273g-5p	PAR-CLIP	21572407
MIRT548027	hsa-miR-4477a	PAR-CLIP	21572407
MIRT548025	hsa-miR-4658	PAR-CLIP	21572407
MIRT548026	hsa-miR-6790-5p	PAR-CLIP	21572407
MIRT548024	hsa-miR-487a-5p	PAR-CLIP	21572407
MIRT548023	hsa-miR-487b-5p	PAR-CLIP	21572407
MIRT526480	hsa-miR-16-1-3p	PAR-CLIP	22012620
MIRT526479	hsa-miR-556-3p	PAR-CLIP	22012620
MIRT526478	hsa-miR-222-5p	PAR-CLIP	22012620
MIRT526477	hsa-miR-30a-3p	PAR-CLIP	22012620
MIRT526476	hsa-miR-30d-3p	PAR-CLIP	22012620
MIRT526475	hsa-miR-30e-3p	PAR-CLIP	22012620
MIRT1026917	hsa-miR-2682	CLIP-seq
MIRT1026918	hsa-miR-3684	CLIP-seq
MIRT1026919	hsa-miR-4305	CLIP-seq
MIRT1026920	hsa-miR-4307	CLIP-seq
MIRT1026921	hsa-miR-449c	CLIP-seq
MIRT2004556	hsa-miR-300	CLIP-seq
MIRT2004557	hsa-miR-381	CLIP-seq
MIRT2004558	hsa-miR-4666-3p	CLIP-seq
MIRT2004559	hsa-miR-494	CLIP-seq
MIRT2004560	hsa-miR-499-3p	CLIP-seq
MIRT2004561	hsa-miR-499a-3p	CLIP-seq
MIRT2004562	hsa-miR-556-5p	CLIP-seq
MIRT2237353	hsa-miR-2116	CLIP-seq
MIRT1026917	hsa-miR-2682	CLIP-seq
MIRT1026920	hsa-miR-4307	CLIP-seq
MIRT1026921	hsa-miR-449c	CLIP-seq
MIRT2237354	hsa-miR-450b-5p	CLIP-seq
MIRT2237355	hsa-miR-4677-5p	CLIP-seq
MIRT2237356	hsa-miR-4742-3p	CLIP-seq
MIRT2237357	hsa-miR-486-5p	CLIP-seq
MIRT2004560	hsa-miR-499-3p	CLIP-seq
MIRT2004561	hsa-miR-499a-3p	CLIP-seq
MIRT2237358	hsa-miR-507	CLIP-seq
MIRT2004562	hsa-miR-556-5p	CLIP-seq
MIRT2237359	hsa-miR-557	CLIP-seq
MIRT2237360	hsa-miR-605	CLIP-seq
MIRT2004556	hsa-miR-300	CLIP-seq
MIRT2004557	hsa-miR-381	CLIP-seq
MIRT2004558	hsa-miR-4666-3p	CLIP-seq
MIRT2004559	hsa-miR-494	CLIP-seq
MIRT2004560	hsa-miR-499-3p	CLIP-seq
MIRT2004561	hsa-miR-499a-3p	CLIP-seq
MIRT2004562	hsa-miR-556-5p	CLIP-seq

Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005768	Component	Endosome	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	9201717
GO:0005794	Component	Golgi apparatus	IEA
GO:0005796	Component	Golgi lumen	TAS	9201717
GO:0005801	Component	Cis-Golgi network	TAS	9201717
GO:0010008	Component	Endosome membrane	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IDA	9201717
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	9201717
GO:0030133	Component	Transport vesicle	TAS
GO:0030139	Component	Endocytic vesicle	TAS	9201717
GO:0032580	Component	Golgi cisterna membrane	IEA

MIM	HGNC	e!Ensembl
606805	15448	ENSG00000173905

O00461

Protein name

Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa)

Protein function

Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi.

Family and domains

Sequence

MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
ENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDT
LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
AHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEA
DRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAG
NPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEV
RDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM

Sequence length

696

Interactions

View interactions

	Reactome
			Intra-Golgi traffic

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (12)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BARRETT'S ESOPHAGUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETIC RETINOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIGESTIVE SYSTEM DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EPILEPSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESOPHAGEAL ADENOCARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GENERALISED EPILEPSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PARTIAL EPILEPSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROLIFERATIVE DIABETIC RETINOPATHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSYCHIATRIC DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (14)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer`s Disease	Alzheimer disease	GWASCAT_DG	29274321		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	33722196	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	34180133	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Head and Neck Carcinoma	Head And Neck Carcinoma	BEFREE	30068697		★★★★★ ★☆☆☆☆ Found in Text Mining only
Head and Neck Neoplasms	Head and neck neoplasm	Pubtator	30068697	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Head and Neck Neoplasms	Head and neck neoplasm	Pubtator	40649939	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	40649939	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Head and Neck Neoplasm	Head and neck cancer	BEFREE	30068697		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	17854043		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	34180133	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30068697		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	40649939	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	30068697	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

GOLIM4 (golgi integral membrane protein 4)