Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	27314
Gene name	RAB30, member RAS oncogene family
Gene symbol	RAB30
Synonyms (NCBI Gene)	-
Chromosome	11
Chromosome location	11q14.1

195

Show/Hide all (195)

miRTarBase ID	miRNA	Experiments	Reference
MIRT000774	hsa-miR-200a-3p	MicroarrayNorthern blot	16331254
MIRT001424	hsa-miR-16-5p	pSILAC	18668040
MIRT020408	hsa-miR-29c-3p	Sequencing	20371350
MIRT020831	hsa-miR-155-5p	Proteomics	18668040
MIRT023855	hsa-miR-1-3p	Proteomics	18668040
MIRT027660	hsa-miR-98-5p	Microarray	19088304
MIRT029648	hsa-miR-26b-5p	Microarray	19088304
MIRT001424	hsa-miR-16-5p	Proteomics;Other	18668040
MIRT687106	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT020831	hsa-miR-155-5p	HITS-CLIP	23313552
MIRT687105	hsa-miR-3176	HITS-CLIP	23313552
MIRT687104	hsa-miR-3922-3p	HITS-CLIP	23313552
MIRT687103	hsa-miR-5008-5p	HITS-CLIP	23313552
MIRT700384	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT687102	hsa-miR-5580-5p	HITS-CLIP	23313552
MIRT687101	hsa-miR-6851-3p	HITS-CLIP	23313552
MIRT687100	hsa-miR-6735-3p	HITS-CLIP	23313552
MIRT687099	hsa-miR-412-5p	HITS-CLIP	23313552
MIRT687106	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT020831	hsa-miR-155-5p	HITS-CLIP	23313552
MIRT687105	hsa-miR-3176	HITS-CLIP	23313552
MIRT687104	hsa-miR-3922-3p	HITS-CLIP	23313552
MIRT687103	hsa-miR-5008-5p	HITS-CLIP	23313552
MIRT687102	hsa-miR-5580-5p	HITS-CLIP	23313552
MIRT687101	hsa-miR-6851-3p	HITS-CLIP	23313552
MIRT687100	hsa-miR-6735-3p	HITS-CLIP	23313552
MIRT687099	hsa-miR-412-5p	HITS-CLIP	23313552
MIRT627782	hsa-miR-3920	HITS-CLIP	23824327
MIRT627781	hsa-miR-29a-5p	HITS-CLIP	23824327
MIRT627780	hsa-miR-190a-5p	HITS-CLIP	23824327
MIRT627779	hsa-miR-190b	HITS-CLIP	23824327
MIRT627778	hsa-miR-508-3p	HITS-CLIP	23824327
MIRT627777	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT627776	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT627775	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT627774	hsa-miR-4445-5p	HITS-CLIP	23824327
MIRT627773	hsa-miR-548aj-5p	HITS-CLIP	23824327
MIRT627772	hsa-miR-548f-5p	HITS-CLIP	23824327
MIRT627771	hsa-miR-548g-5p	HITS-CLIP	23824327
MIRT627770	hsa-miR-548x-5p	HITS-CLIP	23824327
MIRT627769	hsa-miR-1468-3p	HITS-CLIP	23824327
MIRT627768	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT627767	hsa-miR-3192-3p	HITS-CLIP	23824327
MIRT627766	hsa-miR-548aw	HITS-CLIP	23824327
MIRT627765	hsa-miR-218-5p	HITS-CLIP	23824327
MIRT627764	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT534825	hsa-miR-4255	PAR-CLIP	22012620
MIRT534824	hsa-miR-4733-5p	PAR-CLIP	22012620
MIRT534823	hsa-miR-186-3p	PAR-CLIP	22012620
MIRT534822	hsa-miR-1470	PAR-CLIP	22012620
MIRT534821	hsa-miR-4667-3p	PAR-CLIP	22012620
MIRT534820	hsa-miR-142-3p	PAR-CLIP	22012620
MIRT534819	hsa-miR-3591-5p	PAR-CLIP	22012620
MIRT469733	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT469732	hsa-miR-203b-5p	PAR-CLIP	23592263
MIRT469731	hsa-miR-6718-5p	PAR-CLIP	23592263
MIRT469730	hsa-miR-140-5p	PAR-CLIP	23592263
MIRT469729	hsa-miR-656-5p	PAR-CLIP	23592263
MIRT469728	hsa-miR-376a-2-5p	PAR-CLIP	23592263
MIRT469727	hsa-miR-1273g-5p	PAR-CLIP	23592263
MIRT469726	hsa-miR-4727-3p	PAR-CLIP	23592263
MIRT469725	hsa-miR-4460	PAR-CLIP	23592263
MIRT439838	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT439837	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439838	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT726816	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT726815	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT726814	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT726813	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT439837	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT687106	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT020831	hsa-miR-155-5p	HITS-CLIP	23313552
MIRT687105	hsa-miR-3176	HITS-CLIP	23313552
MIRT687104	hsa-miR-3922-3p	HITS-CLIP	23313552
MIRT687103	hsa-miR-5008-5p	HITS-CLIP	23313552
MIRT700384	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT687102	hsa-miR-5580-5p	HITS-CLIP	23313552
MIRT687101	hsa-miR-6851-3p	HITS-CLIP	23313552
MIRT687100	hsa-miR-6735-3p	HITS-CLIP	23313552
MIRT687099	hsa-miR-412-5p	HITS-CLIP	23313552
MIRT687106	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT020831	hsa-miR-155-5p	HITS-CLIP	23313552
MIRT687105	hsa-miR-3176	HITS-CLIP	23313552
MIRT687104	hsa-miR-3922-3p	HITS-CLIP	23313552
MIRT687103	hsa-miR-5008-5p	HITS-CLIP	23313552
MIRT687102	hsa-miR-5580-5p	HITS-CLIP	23313552
MIRT687101	hsa-miR-6851-3p	HITS-CLIP	23313552
MIRT687100	hsa-miR-6735-3p	HITS-CLIP	23313552
MIRT687099	hsa-miR-412-5p	HITS-CLIP	23313552
MIRT627782	hsa-miR-3920	HITS-CLIP	23824327
MIRT627781	hsa-miR-29a-5p	HITS-CLIP	23824327
MIRT627780	hsa-miR-190a-5p	HITS-CLIP	23824327
MIRT627779	hsa-miR-190b	HITS-CLIP	23824327
MIRT627778	hsa-miR-508-3p	HITS-CLIP	23824327
MIRT627777	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT627776	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT627775	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT627774	hsa-miR-4445-5p	HITS-CLIP	23824327
MIRT627773	hsa-miR-548aj-5p	HITS-CLIP	23824327
MIRT627772	hsa-miR-548f-5p	HITS-CLIP	23824327
MIRT627771	hsa-miR-548g-5p	HITS-CLIP	23824327
MIRT627770	hsa-miR-548x-5p	HITS-CLIP	23824327
MIRT627769	hsa-miR-1468-3p	HITS-CLIP	23824327
MIRT627768	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT627767	hsa-miR-3192-3p	HITS-CLIP	23824327
MIRT627766	hsa-miR-548aw	HITS-CLIP	23824327
MIRT627765	hsa-miR-218-5p	HITS-CLIP	23824327
MIRT627764	hsa-miR-4762-3p	HITS-CLIP	23824327
MIRT534825	hsa-miR-4255	PAR-CLIP	22012620
MIRT534824	hsa-miR-4733-5p	PAR-CLIP	22012620
MIRT534823	hsa-miR-186-3p	PAR-CLIP	22012620
MIRT534822	hsa-miR-1470	PAR-CLIP	22012620
MIRT534821	hsa-miR-4667-3p	PAR-CLIP	22012620
MIRT534820	hsa-miR-142-3p	PAR-CLIP	22012620
MIRT534819	hsa-miR-3591-5p	PAR-CLIP	22012620
MIRT469733	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT469732	hsa-miR-203b-5p	PAR-CLIP	23592263
MIRT469731	hsa-miR-6718-5p	PAR-CLIP	23592263
MIRT469730	hsa-miR-140-5p	PAR-CLIP	23592263
MIRT469729	hsa-miR-656-5p	PAR-CLIP	23592263
MIRT469728	hsa-miR-376a-2-5p	PAR-CLIP	23592263
MIRT469727	hsa-miR-1273g-5p	PAR-CLIP	23592263
MIRT469726	hsa-miR-4727-3p	PAR-CLIP	23592263
MIRT469725	hsa-miR-4460	PAR-CLIP	23592263
MIRT1283315	hsa-miR-106a	CLIP-seq
MIRT1283316	hsa-miR-106b	CLIP-seq
MIRT1283317	hsa-miR-1305	CLIP-seq
MIRT1283318	hsa-miR-133a	CLIP-seq
MIRT1283319	hsa-miR-133b	CLIP-seq
MIRT1283320	hsa-miR-136	CLIP-seq
MIRT1283321	hsa-miR-140-3p	CLIP-seq
MIRT1283322	hsa-miR-141	CLIP-seq
MIRT1283323	hsa-miR-17	CLIP-seq
MIRT1283324	hsa-miR-200a	CLIP-seq
MIRT1283325	hsa-miR-20a	CLIP-seq
MIRT1283326	hsa-miR-20b	CLIP-seq
MIRT1283327	hsa-miR-29a	CLIP-seq
MIRT1283328	hsa-miR-29b	CLIP-seq
MIRT1283329	hsa-miR-29c	CLIP-seq
MIRT1283330	hsa-miR-3138	CLIP-seq
MIRT1283331	hsa-miR-361-3p	CLIP-seq
MIRT1283332	hsa-miR-3679-3p	CLIP-seq
MIRT1283333	hsa-miR-4477a	CLIP-seq
MIRT1283334	hsa-miR-4527	CLIP-seq
MIRT1283335	hsa-miR-4633-3p	CLIP-seq
MIRT1283336	hsa-miR-4635	CLIP-seq
MIRT1283337	hsa-miR-4653-3p	CLIP-seq
MIRT1283338	hsa-miR-4677-3p	CLIP-seq
MIRT1283339	hsa-miR-4679	CLIP-seq
MIRT1283340	hsa-miR-4698	CLIP-seq
MIRT1283341	hsa-miR-4795-3p	CLIP-seq
MIRT1283342	hsa-miR-4800-5p	CLIP-seq
MIRT1283343	hsa-miR-4802-5p	CLIP-seq
MIRT1283344	hsa-miR-488	CLIP-seq
MIRT1283345	hsa-miR-490-5p	CLIP-seq
MIRT1283346	hsa-miR-515-3p	CLIP-seq
MIRT1283347	hsa-miR-519d	CLIP-seq
MIRT1283348	hsa-miR-519e	CLIP-seq
MIRT1283349	hsa-miR-521	CLIP-seq
MIRT1283350	hsa-miR-526b	CLIP-seq
MIRT1283351	hsa-miR-539	CLIP-seq
MIRT1283352	hsa-miR-548m	CLIP-seq
MIRT1283353	hsa-miR-550a	CLIP-seq
MIRT1283354	hsa-miR-568	CLIP-seq
MIRT1283355	hsa-miR-579	CLIP-seq
MIRT1283356	hsa-miR-607	CLIP-seq
MIRT1283357	hsa-miR-615-5p	CLIP-seq
MIRT1283358	hsa-miR-617	CLIP-seq
MIRT1283359	hsa-miR-643	CLIP-seq
MIRT1283360	hsa-miR-656	CLIP-seq
MIRT1283361	hsa-miR-93	CLIP-seq
MIRT1283355	hsa-miR-579	CLIP-seq
MIRT1283318	hsa-miR-133a	CLIP-seq
MIRT1283319	hsa-miR-133b	CLIP-seq
MIRT1283327	hsa-miR-29a	CLIP-seq
MIRT1283328	hsa-miR-29b	CLIP-seq
MIRT1283329	hsa-miR-29c	CLIP-seq
MIRT2309375	hsa-miR-3148	CLIP-seq
MIRT2309376	hsa-miR-3918	CLIP-seq
MIRT2309377	hsa-miR-3919	CLIP-seq
MIRT2309378	hsa-miR-3974	CLIP-seq
MIRT2309379	hsa-miR-4433	CLIP-seq
MIRT1283334	hsa-miR-4527	CLIP-seq
MIRT1283335	hsa-miR-4633-3p	CLIP-seq
MIRT1283337	hsa-miR-4653-3p	CLIP-seq
MIRT1283338	hsa-miR-4677-3p	CLIP-seq
MIRT1283339	hsa-miR-4679	CLIP-seq
MIRT2309380	hsa-miR-4756-3p	CLIP-seq
MIRT1283343	hsa-miR-4802-5p	CLIP-seq
MIRT2309381	hsa-miR-493	CLIP-seq
MIRT2309382	hsa-miR-548ad	CLIP-seq
MIRT1283354	hsa-miR-568	CLIP-seq
MIRT1283355	hsa-miR-579	CLIP-seq
MIRT1283359	hsa-miR-643	CLIP-seq
MIRT2309383	hsa-miR-875-3p	CLIP-seq

Show/Hide all (34)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	ISS
GO:0000139	Component	Golgi membrane	TAS
GO:0000166	Function	Nucleotide binding	IEA
GO:0000421	Component	Autophagosome membrane	IDA	26771875
GO:0000421	Component	Autophagosome membrane	IEA
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IEA
GO:0003924	Function	GTPase activity	TAS	9792283
GO:0003925	Function	G protein activity	IDA	22188167
GO:0005515	Function	Protein binding	IPI	16086013, 32296183
GO:0005525	Function	GTP binding	IBA
GO:0005525	Function	GTP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005764	Component	Lysosome	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005795	Component	Golgi stack	TAS	9792283
GO:0005801	Component	Cis-Golgi network	IDA	22188167
GO:0005802	Component	Trans-Golgi network	IBA
GO:0005802	Component	Trans-Golgi network	IDA	22188167
GO:0007030	Process	Golgi organization	IMP	22188167
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031985	Component	Golgi cisterna	IBA
GO:0031985	Component	Golgi cisterna	IDA	22188167
GO:0032482	Process	Rab protein signal transduction	IEA
GO:0033106	Component	Cis-Golgi network membrane	IDA	26771875
GO:0046872	Function	Metal ion binding	IEA
GO:0055088	Process	Lipid homeostasis	IEA
GO:0055088	Process	Lipid homeostasis	ISS
GO:0120281	Component	Autolysosome membrane	IDA	26771875
GO:0120281	Component	Autolysosome membrane	IEA

MIM	HGNC	e!Ensembl
605693	9770	ENSG00000137502

Q15771

Protein name

Ras-related protein Rab-30 (EC 3.6.5.2)

Protein function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r

PDB

2EW1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00071	Ras	11 → 172	Ras family	Domain

Sequence

MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKL
QIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLV
GNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLV
NNVSSPLPGEGKSISYLTCCNFN

Sequence length

203

Interactions

View interactions

	Reactome
			Intra-Golgi traffic RAB geranylgeranylation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34950443	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	30175120	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

RAB30 (RAB30, member RAS oncogene family)