TNFRSF21 (TNF receptor superfamily member 21)

Gene

• Entrez ID: 27242
• Gene name: TNF receptor superfamily member 21
• Gene symbol: TNFRSF21
• Synonyms (NCBI Gene): BM-018, CD358, DR6
• Chromosome: 6
• Chromosome location: 6p12.3
• Summary: This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its deat

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT002620	hsa-miR-124-3p	Microarray	15685193
MIRT016429	hsa-miR-193b-3p	Microarray	20304954
MIRT020190	hsa-miR-130b-3p	Sequencing	20371350
MIRT002620	hsa-miR-124-3p	Microarray	18668037
MIRT002620	hsa-miR-124-3p	Microarray	15685193
MIRT027534	hsa-miR-98-5p	Microarray	19088304
MIRT028037	hsa-miR-93-5p	Sequencing	20371350
MIRT608425	hsa-miR-8485	HITS-CLIP	22927820
MIRT608425	hsa-miR-8485	HITS-CLIP	23313552
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT664409	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	23824327
MIRT611628	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611627	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT608425	hsa-miR-8485	HITS-CLIP	24906430
MIRT608425	hsa-miR-8485	HITS-CLIP	24906430
MIRT565284	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT565283	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT565282	hsa-miR-8076	PAR-CLIP	20371350
MIRT565281	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT565280	hsa-miR-4698	PAR-CLIP	20371350
MIRT565279	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT565278	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT565277	hsa-miR-4434	PAR-CLIP	20371350
MIRT565275	hsa-miR-4516	PAR-CLIP	20371350
MIRT565276	hsa-miR-5703	PAR-CLIP	20371350
MIRT565274	hsa-miR-3653-3p	PAR-CLIP	20371350
MIRT565273	hsa-miR-4531	PAR-CLIP	20371350
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT439412	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT439410	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439412	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT546261	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT546258	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT028037	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT546259	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT439410	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT575065	hsa-miR-329-3p	HITS-CLIP	27418678
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT575064	hsa-miR-362-3p	HITS-CLIP	27418678
MIRT664409	hsa-miR-548c-3p	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	27418678
MIRT575066	hsa-miR-8485	HITS-CLIP	22927820
MIRT575066	hsa-miR-8485	HITS-CLIP	23313552
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT664409	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620601	hsa-miR-3065-5p	HITS-CLIP	23824327
MIRT614708	hsa-miR-3529-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT575066	hsa-miR-8485	HITS-CLIP	23824327
MIRT575065	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT575064	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT565284	hsa-miR-4694-3p	PAR-CLIP	20371350
MIRT565283	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT565282	hsa-miR-8076	PAR-CLIP	20371350
MIRT565281	hsa-miR-3688-3p	PAR-CLIP	20371350
MIRT565280	hsa-miR-4698	PAR-CLIP	20371350
MIRT565279	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT565278	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT565277	hsa-miR-4434	PAR-CLIP	20371350
MIRT565275	hsa-miR-4516	PAR-CLIP	20371350
MIRT565276	hsa-miR-5703	PAR-CLIP	20371350
MIRT565274	hsa-miR-3653-3p	PAR-CLIP	20371350
MIRT565273	hsa-miR-4531	PAR-CLIP	20371350
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT439412	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT546261	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT439410	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT028037	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT546260	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT546259	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT546258	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT546257	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT546256	hsa-miR-3609	PAR-CLIP	21572407
MIRT546255	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT546254	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT546253	hsa-miR-3606-3p	PAR-CLIP	21572407
MIRT546252	hsa-miR-513a-3p	PAR-CLIP	21572407
MIRT546251	hsa-miR-513c-3p	PAR-CLIP	21572407
MIRT546250	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT546249	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT546248	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT546247	hsa-miR-217	PAR-CLIP	21572407
MIRT546245	hsa-miR-6807-3p	PAR-CLIP	21572407
MIRT546246	hsa-miR-5579-5p	PAR-CLIP	21572407
MIRT546244	hsa-miR-4729	PAR-CLIP	21572407
MIRT546243	hsa-miR-20a-3p	PAR-CLIP	21572407
MIRT546242	hsa-miR-4635	PAR-CLIP	21572407
MIRT546241	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT1443085	hsa-miR-219-2-3p	CLIP-seq
MIRT1443086	hsa-miR-224	CLIP-seq
MIRT1443087	hsa-miR-2964a-3p	CLIP-seq
MIRT1443088	hsa-miR-3133	CLIP-seq
MIRT1443089	hsa-miR-3159	CLIP-seq
MIRT1443090	hsa-miR-329	CLIP-seq
MIRT1443091	hsa-miR-33a	CLIP-seq
MIRT1443092	hsa-miR-33b	CLIP-seq
MIRT1443093	hsa-miR-3647-3p	CLIP-seq
MIRT1443094	hsa-miR-3653	CLIP-seq
MIRT1443095	hsa-miR-3658	CLIP-seq
MIRT740224	hsa-miR-3925-3p	CLIP-seq
MIRT1443096	hsa-miR-3973	CLIP-seq
MIRT1443097	hsa-miR-3978	CLIP-seq
MIRT1443098	hsa-miR-4252	CLIP-seq
MIRT1443099	hsa-miR-4311	CLIP-seq
MIRT1443100	hsa-miR-4428	CLIP-seq
MIRT1443101	hsa-miR-4452	CLIP-seq
MIRT1443102	hsa-miR-4457	CLIP-seq
MIRT1443103	hsa-miR-4511	CLIP-seq
MIRT1443104	hsa-miR-4528	CLIP-seq
MIRT740222	hsa-miR-4690-3p	CLIP-seq
MIRT1443105	hsa-miR-513b	CLIP-seq
MIRT740225	hsa-miR-515-5p	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT1443110	hsa-miR-548ah	CLIP-seq
MIRT1443111	hsa-miR-548u	CLIP-seq
MIRT740226	hsa-miR-579	CLIP-seq
MIRT1443112	hsa-miR-584	CLIP-seq
MIRT740223	hsa-miR-766	CLIP-seq
MIRT1443113	hsa-miR-888	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2353613	hsa-miR-1179	CLIP-seq
MIRT2353614	hsa-miR-125a-3p	CLIP-seq
MIRT2353615	hsa-miR-1301	CLIP-seq
MIRT2353616	hsa-miR-147	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT2353617	hsa-miR-1825	CLIP-seq
MIRT2353618	hsa-miR-197	CLIP-seq
MIRT2353619	hsa-miR-198	CLIP-seq
MIRT2353620	hsa-miR-199a-5p	CLIP-seq
MIRT2353621	hsa-miR-199b-5p	CLIP-seq
MIRT2353622	hsa-miR-205	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT1443086	hsa-miR-224	CLIP-seq
MIRT2353623	hsa-miR-3128	CLIP-seq
MIRT2353624	hsa-miR-3153	CLIP-seq
MIRT1443090	hsa-miR-329	CLIP-seq
MIRT1443094	hsa-miR-3653	CLIP-seq
MIRT2353625	hsa-miR-3911	CLIP-seq
MIRT2353626	hsa-miR-412	CLIP-seq
MIRT1443098	hsa-miR-4252	CLIP-seq
MIRT2353627	hsa-miR-4302	CLIP-seq
MIRT2353628	hsa-miR-4648	CLIP-seq
MIRT2353629	hsa-miR-4654	CLIP-seq
MIRT2353630	hsa-miR-4668-5p	CLIP-seq
MIRT2353631	hsa-miR-4670-3p	CLIP-seq
MIRT2353632	hsa-miR-4769-5p	CLIP-seq
MIRT2353633	hsa-miR-5047	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT2353634	hsa-miR-548aa	CLIP-seq
MIRT2353635	hsa-miR-570	CLIP-seq
MIRT2353636	hsa-miR-582-5p	CLIP-seq
MIRT2353637	hsa-miR-600	CLIP-seq
MIRT2353638	hsa-miR-602	CLIP-seq
MIRT2353639	hsa-miR-644	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT2396121	hsa-miR-3910	CLIP-seq
MIRT2396122	hsa-miR-4493	CLIP-seq
MIRT2396123	hsa-miR-4762-3p	CLIP-seq
MIRT2462070	hsa-miR-103a	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2462071	hsa-miR-107	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT1443090	hsa-miR-329	CLIP-seq
MIRT2462072	hsa-miR-3944-5p	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT2462070	hsa-miR-103a	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2462071	hsa-miR-107	CLIP-seq
MIRT2647791	hsa-miR-1185	CLIP-seq
MIRT2647792	hsa-miR-1224-5p	CLIP-seq
MIRT2647793	hsa-miR-1297	CLIP-seq
MIRT2647794	hsa-miR-135a	CLIP-seq
MIRT2647795	hsa-miR-135b	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT2647796	hsa-miR-26a	CLIP-seq
MIRT2647797	hsa-miR-26b	CLIP-seq
MIRT2647798	hsa-miR-3121-3p	CLIP-seq
MIRT2647799	hsa-miR-3136-3p	CLIP-seq
MIRT2647800	hsa-miR-3167	CLIP-seq
MIRT2647801	hsa-miR-3180-5p	CLIP-seq
MIRT2647802	hsa-miR-3605-5p	CLIP-seq
MIRT2647803	hsa-miR-3679-5p	CLIP-seq
MIRT2647804	hsa-miR-3908	CLIP-seq
MIRT2647805	hsa-miR-3915	CLIP-seq
MIRT2462072	hsa-miR-3944-5p	CLIP-seq
MIRT2647806	hsa-miR-4465	CLIP-seq
MIRT2353631	hsa-miR-4670-3p	CLIP-seq
MIRT2647807	hsa-miR-4689	CLIP-seq
MIRT2647808	hsa-miR-4762-5p	CLIP-seq
MIRT2647809	hsa-miR-4773	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT2647810	hsa-miR-520a-5p	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT2647811	hsa-miR-525-5p	CLIP-seq
MIRT2647812	hsa-miR-548p	CLIP-seq
MIRT2647813	hsa-miR-663b	CLIP-seq
MIRT2647814	hsa-miR-876-5p	CLIP-seq
MIRT2647815	hsa-miR-9	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq
MIRT2462070	hsa-miR-103a	CLIP-seq
MIRT1443080	hsa-miR-106a	CLIP-seq
MIRT1443081	hsa-miR-106b	CLIP-seq
MIRT2462071	hsa-miR-107	CLIP-seq
MIRT2647791	hsa-miR-1185	CLIP-seq
MIRT2647792	hsa-miR-1224-5p	CLIP-seq
MIRT2647793	hsa-miR-1297	CLIP-seq
MIRT2647794	hsa-miR-135a	CLIP-seq
MIRT2647795	hsa-miR-135b	CLIP-seq
MIRT1443082	hsa-miR-17	CLIP-seq
MIRT1443083	hsa-miR-20a	CLIP-seq
MIRT1443084	hsa-miR-20b	CLIP-seq
MIRT2647796	hsa-miR-26a	CLIP-seq
MIRT2647797	hsa-miR-26b	CLIP-seq
MIRT2647798	hsa-miR-3121-3p	CLIP-seq
MIRT2647799	hsa-miR-3136-3p	CLIP-seq
MIRT2647800	hsa-miR-3167	CLIP-seq
MIRT2647801	hsa-miR-3180-5p	CLIP-seq
MIRT2647802	hsa-miR-3605-5p	CLIP-seq
MIRT2647803	hsa-miR-3679-5p	CLIP-seq
MIRT2647804	hsa-miR-3908	CLIP-seq
MIRT2647805	hsa-miR-3915	CLIP-seq
MIRT2462072	hsa-miR-3944-5p	CLIP-seq
MIRT2647806	hsa-miR-4465	CLIP-seq
MIRT2353631	hsa-miR-4670-3p	CLIP-seq
MIRT2647807	hsa-miR-4689	CLIP-seq
MIRT2647808	hsa-miR-4762-5p	CLIP-seq
MIRT2647809	hsa-miR-4773	CLIP-seq
MIRT1443106	hsa-miR-519a	CLIP-seq
MIRT1443107	hsa-miR-519d	CLIP-seq
MIRT2647810	hsa-miR-520a-5p	CLIP-seq
MIRT1443108	hsa-miR-520g	CLIP-seq
MIRT1443109	hsa-miR-520h	CLIP-seq
MIRT2647811	hsa-miR-525-5p	CLIP-seq
MIRT2647812	hsa-miR-548p	CLIP-seq
MIRT2647813	hsa-miR-663b	CLIP-seq
MIRT2647814	hsa-miR-876-5p	CLIP-seq
MIRT2647815	hsa-miR-9	CLIP-seq
MIRT1443114	hsa-miR-93	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
VDR	Activation	12520529

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001783	Process	B cell apoptotic process	IEA
GO:0001783	Process	B cell apoptotic process	ISS
GO:0002250	Process	Adaptive immune response	IBA
GO:0002250	Process	Adaptive immune response	IEA
GO:0002250	Process	Adaptive immune response	ISS
GO:0002376	Process	Immune system process	IEA
GO:0005515	Function	Protein binding	IPI	23559013, 32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	19654028
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	IMP	22761420
GO:0006959	Process	Humoral immune response	IBA
GO:0006959	Process	Humoral immune response	IEA
GO:0006959	Process	Humoral immune response	ISS
GO:0007165	Process	Signal transduction	IEA
GO:0007413	Process	Axonal fasciculation	IEA
GO:0016020	Component	Membrane	IEA
GO:0030889	Process	Negative regulation of B cell proliferation	IBA
GO:0030889	Process	Negative regulation of B cell proliferation	IEA
GO:0030889	Process	Negative regulation of B cell proliferation	ISS
GO:0031642	Process	Negative regulation of myelination	IBA
GO:0031642	Process	Negative regulation of myelination	IMP	21725297
GO:0032693	Process	Negative regulation of interleukin-10 production	IEA
GO:0032693	Process	Negative regulation of interleukin-10 production	ISS
GO:0032696	Process	Negative regulation of interleukin-13 production	IEA
GO:0032696	Process	Negative regulation of interleukin-13 production	ISS
GO:0032714	Process	Negative regulation of interleukin-5 production	IEA
GO:0032714	Process	Negative regulation of interleukin-5 production	ISS
GO:0042130	Process	Negative regulation of T cell proliferation	IBA
GO:0042130	Process	Negative regulation of T cell proliferation	IEA
GO:0042130	Process	Negative regulation of T cell proliferation	ISS
GO:0042552	Process	Myelination	IEA
GO:0042552	Process	Myelination	ISS
GO:0048713	Process	Regulation of oligodendrocyte differentiation	IEA
GO:0048713	Process	Regulation of oligodendrocyte differentiation	ISS
GO:0050852	Process	T cell receptor signaling pathway	IEA
GO:0050852	Process	T cell receptor signaling pathway	ISS
GO:0051402	Process	Neuron apoptotic process	IBA
GO:0051402	Process	Neuron apoptotic process	IEA
GO:0071356	Process	Cellular response to tumor necrosis factor	IDA	19654028
GO:0097252	Process	Oligodendrocyte apoptotic process	IBA
GO:0097252	Process	Oligodendrocyte apoptotic process	IEA
GO:0097252	Process	Oligodendrocyte apoptotic process	ISS

Other IDs

• MIM: 605732
• HGNC: 13469
• e!Ensembl: ENSG00000146072

Protein

• UniProt ID: O75509
• Protein name: Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
• Protein function: Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers th
• PDB: 2DBH, 3QO4, 3U3P, 3U3Q, 3U3S, 3U3T, 3U3V
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00020	TNFR_c6	51 → 88	TNFR/NGFR cysteine-rich region	Domain
  PF00020	TNFR_c6	91 → 131	TNFR/NGFR cysteine-rich region	Domain
  PF00020	TNFR_c6	171 → 211	TNFR/NGFR cysteine-rich region	Domain
  PF00531	Death	417 → 498	Death domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in fetal spinal cord and in brain neurons, with higher levels in brain from Alzheimer disease patients (at protein level). Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lowe
• Sequence:

  MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
  TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
  LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
  SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
  VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
  QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
  VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
  LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
  ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP
  SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF
  DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL

• Sequence length: 655

Pathways

KEGG:

Cytokine-cytokine receptor interaction

Reactome:

PPARA activates gene expression

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AMYOTROPHIC LATERAL SCLEROSIS	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ASTROCYTOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOPIA	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OROFACIAL CLEFT	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PANIC DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
STROKE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	BEFREE	24113175		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	CTD_human_DG	24113175		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Amyotrophic Lateral Sclerosis With Dementia	Amyotrophic Lateral Sclerosis With Dementia	CTD_human_DG	24113175		★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis, Guam Form	Amyotrophic lateral sclerosis	CTD_human_DG	24113175		★☆☆☆☆ Found in Text Mining only
Angioimmunoblastic Lymphadenopathy	Angioimmunoblastic T-cell lymphoma	BEFREE	28148900		★☆☆☆☆ Found in Text Mining only
Arthritis Juvenile	Juvenile arthritis	Pubtator	10513798	Associate	★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	10765920, 37510374	Associate	★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	11247876, 6428222, 7788148	Inhibit	★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	31092421		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autoimmune Diseases	Autoimmune Diseases	BEFREE	28045014		★☆☆☆☆ Found in Text Mining only
Biliary Atresia	Biliary atresia	Pubtator	9149338	Associate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	40332226	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	35593591	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	25113253		★☆☆☆☆ Found in Text Mining only
Dental Caries	Dental caries	Pubtator	9824493	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 1	Diabetes mellitus, type 1	Pubtator	3456197	Associate	★☆☆☆☆ Found in Text Mining only
Endometriosis	Endometriosis	BEFREE	24028773		★☆☆☆☆ Found in Text Mining only
GATA2 Deficiency	Gata2 deficiency	Pubtator	19965620	Associate	★☆☆☆☆ Found in Text Mining only
Glaucoma	Glaucoma	Pubtator	7742275	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	22802048	Associate	★☆☆☆☆ Found in Text Mining only
Gliosarcoma	Gliosarcoma	Pubtator	22567163	Associate	★☆☆☆☆ Found in Text Mining only
Hepatitis Alcoholic	Alcoholic hepatitis	Pubtator	40649881	Associate	★☆☆☆☆ Found in Text Mining only
Hepatitis C	Hepatitis c	Pubtator	28743875	Stimulate	★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	7742275	Inhibit	★☆☆☆☆ Found in Text Mining only
Kidney Failure, Acute	Kidney Failure	BEFREE	27622990		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	40109864	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	25113253		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	CTD_human_DG	11753679		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	25113253, 30186750, 31092421		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	31092421		★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	24113175		★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	36807122	Associate	★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	25113253		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	22567163, 25113253	Associate	★☆☆☆☆ Found in Text Mining only
Pemphigus	Pemphigus	Pubtator	10417627, 8426112	Associate	★☆☆☆☆ Found in Text Mining only
Periodontitis	Periodontitis	Pubtator	35154475	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	CTD_human_DG	11753679		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoidosis	Sarcoidosis	Pubtator	7742275	Associate	★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	Pubtator	22567163	Stimulate	★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	BEFREE	31092421		★☆☆☆☆ Found in Text Mining only
Sarcoma Synovial	Synovial sarcoma	Pubtator	22567163	Stimulate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	39702278	Associate	★☆☆☆☆ Found in Text Mining only
Thyroiditis Autoimmune	Thyroiditis	Pubtator	3456197	Associate	★☆☆☆☆ Found in Text Mining only