UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII)

Gene

• Entrez ID: 27089
• Gene name: Ubiquinol-cytochrome c reductase complex III subunit VII
• Gene symbol: UQCRQ
• Synonyms (NCBI Gene): MC3DN4, QCR8, QP-C, QPC, UQCR7
• Chromosome: 5
• Chromosome location: 5q31.1
• Summary: This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq,

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020113	hsa-miR-130b-3p	Sequencing	20371350
MIRT025979	hsa-miR-148a-3p	Sequencing	20371350
MIRT044341	hsa-miR-106b-5p	CLASH	23622248
MIRT041651	hsa-miR-484	CLASH	23622248
MIRT041651	hsa-miR-484	CLASH	23622248
MIRT645080	hsa-miR-3929	HITS-CLIP	23824327
MIRT645079	hsa-miR-4419b	HITS-CLIP	23824327
MIRT645078	hsa-miR-4478	HITS-CLIP	23824327
MIRT645077	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT645047	hsa-miR-665	HITS-CLIP	23824327
MIRT645076	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT645075	hsa-miR-3197	HITS-CLIP	23824327
MIRT645074	hsa-miR-6087	HITS-CLIP	23824327
MIRT645073	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT645072	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT645071	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT645070	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT645069	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT645068	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT645067	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT645066	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT645065	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT645064	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT662635	hsa-miR-7977	HITS-CLIP	23824327
MIRT645063	hsa-miR-6765-5p	HITS-CLIP	23824327
MIRT645062	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT645061	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT645060	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT645059	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT645058	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT645057	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT645056	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT645055	hsa-miR-3689c	HITS-CLIP	23824327
MIRT645054	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT645053	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT645052	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT645051	hsa-miR-3122	HITS-CLIP	23824327
MIRT645050	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT645049	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT645048	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT645081	hsa-miR-5694	HITS-CLIP	23824327
MIRT645080	hsa-miR-3929	HITS-CLIP	23824327
MIRT645079	hsa-miR-4419b	HITS-CLIP	23824327
MIRT645078	hsa-miR-4478	HITS-CLIP	23824327
MIRT645077	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT645076	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT645075	hsa-miR-3197	HITS-CLIP	23824327
MIRT645074	hsa-miR-6087	HITS-CLIP	23824327
MIRT645073	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT645072	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT645071	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT645070	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT645069	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT645068	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT645067	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT645066	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT645065	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT645064	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT645063	hsa-miR-6765-5p	HITS-CLIP	23824327
MIRT645062	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT645061	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT645060	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT645059	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT645058	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT645057	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT645056	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT645055	hsa-miR-3689c	HITS-CLIP	23824327
MIRT645054	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT645053	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT645052	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT645051	hsa-miR-3122	HITS-CLIP	23824327
MIRT645050	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT645049	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT645048	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT645047	hsa-miR-665	HITS-CLIP	23824327
MIRT645080	hsa-miR-3929	HITS-CLIP	23824327
MIRT645079	hsa-miR-4419b	HITS-CLIP	23824327
MIRT645078	hsa-miR-4478	HITS-CLIP	23824327
MIRT645077	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT645047	hsa-miR-665	HITS-CLIP	23824327
MIRT645076	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT645075	hsa-miR-3197	HITS-CLIP	23824327
MIRT645074	hsa-miR-6087	HITS-CLIP	23824327
MIRT645073	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT645072	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT645071	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT645070	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT645069	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT645068	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT645067	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT645066	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT645065	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT645064	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT662635	hsa-miR-7977	HITS-CLIP	23824327
MIRT645063	hsa-miR-6765-5p	HITS-CLIP	23824327
MIRT645062	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT645061	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT645060	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT645059	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT645058	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT645057	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT645056	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT645055	hsa-miR-3689c	HITS-CLIP	23824327
MIRT645054	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT645053	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT645052	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT645051	hsa-miR-3122	HITS-CLIP	23824327
MIRT645050	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT645049	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT645048	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT645081	hsa-miR-5694	HITS-CLIP	23824327
MIRT645080	hsa-miR-3929	HITS-CLIP	23824327
MIRT645079	hsa-miR-4419b	HITS-CLIP	23824327
MIRT645078	hsa-miR-4478	HITS-CLIP	23824327
MIRT645077	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT645076	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT645075	hsa-miR-3197	HITS-CLIP	23824327
MIRT645074	hsa-miR-6087	HITS-CLIP	23824327
MIRT645073	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT645072	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT645071	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT645070	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT645069	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT645068	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT645067	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT645066	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT645065	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT645064	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT645063	hsa-miR-6765-5p	HITS-CLIP	23824327
MIRT645062	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT645061	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT645060	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT645059	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT645058	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT645057	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT645056	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT645055	hsa-miR-3689c	HITS-CLIP	23824327
MIRT645054	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT645053	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT645052	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT645051	hsa-miR-3122	HITS-CLIP	23824327
MIRT645050	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT645049	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT645048	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT645047	hsa-miR-665	HITS-CLIP	23824327
MIRT1476744	hsa-miR-147	CLIP-seq
MIRT1476745	hsa-miR-148a	CLIP-seq
MIRT1476746	hsa-miR-148b	CLIP-seq
MIRT1476747	hsa-miR-152	CLIP-seq
MIRT1476748	hsa-miR-1915	CLIP-seq
MIRT1476749	hsa-miR-2054	CLIP-seq
MIRT1476750	hsa-miR-3136-3p	CLIP-seq
MIRT1476751	hsa-miR-3166	CLIP-seq
MIRT1476752	hsa-miR-3180-5p	CLIP-seq
MIRT1476753	hsa-miR-3200-5p	CLIP-seq
MIRT1476754	hsa-miR-380	CLIP-seq
MIRT1476755	hsa-miR-3911	CLIP-seq
MIRT1476756	hsa-miR-3926	CLIP-seq
MIRT1476757	hsa-miR-4421	CLIP-seq
MIRT1476758	hsa-miR-4433	CLIP-seq
MIRT1476759	hsa-miR-4459	CLIP-seq
MIRT1476760	hsa-miR-4476	CLIP-seq
MIRT1476761	hsa-miR-4684-5p	CLIP-seq
MIRT1476762	hsa-miR-4709-5p	CLIP-seq
MIRT1476763	hsa-miR-4768-3p	CLIP-seq
MIRT1476764	hsa-miR-4771	CLIP-seq
MIRT1476765	hsa-miR-520a-5p	CLIP-seq
MIRT1476766	hsa-miR-525-5p	CLIP-seq
MIRT1476767	hsa-miR-548s	CLIP-seq
MIRT1476768	hsa-miR-593	CLIP-seq
MIRT1476769	hsa-miR-644	CLIP-seq
MIRT1476770	hsa-miR-649	CLIP-seq
MIRT1476771	hsa-miR-663b	CLIP-seq
MIRT1476772	hsa-miR-889	CLIP-seq
MIRT1555351	hsa-miR-4757-5p	CLIP-seq
MIRT1555352	hsa-miR-563	CLIP-seq
MIRT1555353	hsa-miR-570	CLIP-seq
MIRT1555354	hsa-miR-584	CLIP-seq
MIRT2143645	hsa-miR-1236	CLIP-seq
MIRT1476745	hsa-miR-148a	CLIP-seq
MIRT1476746	hsa-miR-148b	CLIP-seq
MIRT1476747	hsa-miR-152	CLIP-seq
MIRT1476751	hsa-miR-3166	CLIP-seq
MIRT1476752	hsa-miR-3180-5p	CLIP-seq
MIRT1476753	hsa-miR-3200-5p	CLIP-seq
MIRT2143646	hsa-miR-338-5p	CLIP-seq
MIRT2143647	hsa-miR-3919	CLIP-seq
MIRT1476756	hsa-miR-3926	CLIP-seq
MIRT2143648	hsa-miR-3942-3p	CLIP-seq
MIRT1476758	hsa-miR-4433	CLIP-seq
MIRT1476759	hsa-miR-4459	CLIP-seq
MIRT1476762	hsa-miR-4709-5p	CLIP-seq
MIRT2143649	hsa-miR-4756-3p	CLIP-seq
MIRT1476763	hsa-miR-4768-3p	CLIP-seq
MIRT1476764	hsa-miR-4771	CLIP-seq
MIRT2143650	hsa-miR-4789-3p	CLIP-seq
MIRT1476765	hsa-miR-520a-5p	CLIP-seq
MIRT1476766	hsa-miR-525-5p	CLIP-seq
MIRT1476767	hsa-miR-548s	CLIP-seq
MIRT2143651	hsa-miR-642b	CLIP-seq
MIRT2363842	hsa-miR-1228	CLIP-seq
MIRT2363843	hsa-miR-1262	CLIP-seq
MIRT1476745	hsa-miR-148a	CLIP-seq
MIRT1476746	hsa-miR-148b	CLIP-seq
MIRT1476747	hsa-miR-152	CLIP-seq
MIRT1476749	hsa-miR-2054	CLIP-seq
MIRT2363844	hsa-miR-3117-5p	CLIP-seq
MIRT1476751	hsa-miR-3166	CLIP-seq
MIRT1476752	hsa-miR-3180-5p	CLIP-seq
MIRT2143646	hsa-miR-338-5p	CLIP-seq
MIRT2363845	hsa-miR-34a	CLIP-seq
MIRT2363846	hsa-miR-34c-5p	CLIP-seq
MIRT2363847	hsa-miR-3672	CLIP-seq
MIRT2143647	hsa-miR-3919	CLIP-seq
MIRT1476756	hsa-miR-3926	CLIP-seq
MIRT1476758	hsa-miR-4433	CLIP-seq
MIRT1476759	hsa-miR-4459	CLIP-seq
MIRT1476760	hsa-miR-4476	CLIP-seq
MIRT2363848	hsa-miR-449a	CLIP-seq
MIRT2363849	hsa-miR-449b	CLIP-seq
MIRT2363850	hsa-miR-4520a-3p	CLIP-seq
MIRT2363851	hsa-miR-4520b-3p	CLIP-seq
MIRT2363852	hsa-miR-4537	CLIP-seq
MIRT2363853	hsa-miR-4701-3p	CLIP-seq
MIRT1476762	hsa-miR-4709-5p	CLIP-seq
MIRT2363854	hsa-miR-4711-3p	CLIP-seq
MIRT1555351	hsa-miR-4757-5p	CLIP-seq
MIRT1476763	hsa-miR-4768-3p	CLIP-seq
MIRT1476764	hsa-miR-4771	CLIP-seq
MIRT2363855	hsa-miR-4793-3p	CLIP-seq
MIRT2363856	hsa-miR-508-5p	CLIP-seq
MIRT2363857	hsa-miR-511	CLIP-seq
MIRT1476765	hsa-miR-520a-5p	CLIP-seq
MIRT1476766	hsa-miR-525-5p	CLIP-seq
MIRT1476767	hsa-miR-548s	CLIP-seq
MIRT2363858	hsa-miR-592	CLIP-seq
MIRT2363859	hsa-miR-599	CLIP-seq
MIRT2363860	hsa-miR-661	CLIP-seq
MIRT2363861	hsa-miR-766	CLIP-seq
MIRT1476772	hsa-miR-889	CLIP-seq
MIRT2396722	hsa-miR-2278	CLIP-seq
MIRT1476752	hsa-miR-3180-5p	CLIP-seq
MIRT1476753	hsa-miR-3200-5p	CLIP-seq
MIRT2143647	hsa-miR-3919	CLIP-seq
MIRT1476756	hsa-miR-3926	CLIP-seq
MIRT1476758	hsa-miR-4433	CLIP-seq
MIRT1476759	hsa-miR-4459	CLIP-seq
MIRT1476763	hsa-miR-4768-3p	CLIP-seq
MIRT1476765	hsa-miR-520a-5p	CLIP-seq
MIRT1476766	hsa-miR-525-5p	CLIP-seq
MIRT1476767	hsa-miR-548s	CLIP-seq
MIRT2363843	hsa-miR-1262	CLIP-seq
MIRT2462960	hsa-miR-3150b-3p	CLIP-seq
MIRT2462961	hsa-miR-3184	CLIP-seq
MIRT2462962	hsa-miR-3613-3p	CLIP-seq
MIRT2462963	hsa-miR-3934	CLIP-seq
MIRT2462964	hsa-miR-423-5p	CLIP-seq
MIRT1476757	hsa-miR-4421	CLIP-seq
MIRT2462965	hsa-miR-4662a-5p	CLIP-seq
MIRT2462966	hsa-miR-4663	CLIP-seq
MIRT2462967	hsa-miR-4676-5p	CLIP-seq
MIRT1476761	hsa-miR-4684-5p	CLIP-seq
MIRT2462968	hsa-miR-4689	CLIP-seq
MIRT2363853	hsa-miR-4701-3p	CLIP-seq
MIRT2462969	hsa-miR-4728-3p	CLIP-seq
MIRT2462970	hsa-miR-4779	CLIP-seq
MIRT2462971	hsa-miR-4784	CLIP-seq
MIRT2363855	hsa-miR-4793-3p	CLIP-seq
MIRT2363856	hsa-miR-508-5p	CLIP-seq
MIRT2462972	hsa-miR-548c-3p	CLIP-seq
MIRT2462973	hsa-miR-575	CLIP-seq
MIRT1476768	hsa-miR-593	CLIP-seq
MIRT1476770	hsa-miR-649	CLIP-seq
MIRT2363860	hsa-miR-661	CLIP-seq
MIRT2363861	hsa-miR-766	CLIP-seq
MIRT2363843	hsa-miR-1262	CLIP-seq
MIRT2462962	hsa-miR-3613-3p	CLIP-seq
MIRT1476757	hsa-miR-4421	CLIP-seq
MIRT1476761	hsa-miR-4684-5p	CLIP-seq
MIRT2363853	hsa-miR-4701-3p	CLIP-seq
MIRT2363855	hsa-miR-4793-3p	CLIP-seq
MIRT2363856	hsa-miR-508-5p	CLIP-seq
MIRT2462972	hsa-miR-548c-3p	CLIP-seq
MIRT1476768	hsa-miR-593	CLIP-seq
MIRT1476770	hsa-miR-649	CLIP-seq
MIRT2363860	hsa-miR-661	CLIP-seq
MIRT2363861	hsa-miR-766	CLIP-seq
MIRT2363843	hsa-miR-1262	CLIP-seq
MIRT1476744	hsa-miR-147	CLIP-seq
MIRT1476748	hsa-miR-1915	CLIP-seq
MIRT1476750	hsa-miR-3136-3p	CLIP-seq
MIRT2462962	hsa-miR-3613-3p	CLIP-seq
MIRT2657678	hsa-miR-371-5p	CLIP-seq
MIRT2657679	hsa-miR-371b-5p	CLIP-seq
MIRT1476755	hsa-miR-3911	CLIP-seq
MIRT2462963	hsa-miR-3934	CLIP-seq
MIRT1476757	hsa-miR-4421	CLIP-seq
MIRT2657680	hsa-miR-4432	CLIP-seq
MIRT2657681	hsa-miR-451b	CLIP-seq
MIRT2462965	hsa-miR-4662a-5p	CLIP-seq
MIRT2462967	hsa-miR-4676-5p	CLIP-seq
MIRT1476761	hsa-miR-4684-5p	CLIP-seq
MIRT2657682	hsa-miR-4696	CLIP-seq
MIRT2363853	hsa-miR-4701-3p	CLIP-seq
MIRT2363855	hsa-miR-4793-3p	CLIP-seq
MIRT2363856	hsa-miR-508-5p	CLIP-seq
MIRT2462972	hsa-miR-548c-3p	CLIP-seq
MIRT2462973	hsa-miR-575	CLIP-seq
MIRT1476768	hsa-miR-593	CLIP-seq
MIRT1476769	hsa-miR-644	CLIP-seq
MIRT1476770	hsa-miR-649	CLIP-seq
MIRT2363860	hsa-miR-661	CLIP-seq
MIRT1476771	hsa-miR-663b	CLIP-seq
MIRT2363861	hsa-miR-766	CLIP-seq
MIRT1476744	hsa-miR-147	CLIP-seq
MIRT1476748	hsa-miR-1915	CLIP-seq
MIRT1476750	hsa-miR-3136-3p	CLIP-seq
MIRT2462962	hsa-miR-3613-3p	CLIP-seq
MIRT1476755	hsa-miR-3911	CLIP-seq
MIRT2462963	hsa-miR-3934	CLIP-seq
MIRT1476757	hsa-miR-4421	CLIP-seq
MIRT2462965	hsa-miR-4662a-5p	CLIP-seq
MIRT2462967	hsa-miR-4676-5p	CLIP-seq
MIRT1476761	hsa-miR-4684-5p	CLIP-seq
MIRT2462972	hsa-miR-548c-3p	CLIP-seq
MIRT2462973	hsa-miR-575	CLIP-seq
MIRT1476768	hsa-miR-593	CLIP-seq
MIRT1476769	hsa-miR-644	CLIP-seq
MIRT1476770	hsa-miR-649	CLIP-seq
MIRT1476771	hsa-miR-663b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	28844695
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	TAS
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	IBA
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	IEA
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	NAS	28844695
GO:0016020	Component	Membrane	IEA
GO:0021539	Process	Subthalamus development	IEA
GO:0021548	Process	Pons development	IEA
GO:0021680	Process	Cerebellar Purkinje cell layer development	IEA
GO:0021766	Process	Hippocampus development	IEA
GO:0021794	Process	Thalamus development	IEA
GO:0021854	Process	Hypothalamus development	IEA
GO:0021860	Process	Pyramidal neuron development	IEA
GO:0030901	Process	Midbrain development	IEA
GO:0045275	Component	Respiratory chain complex III	IBA
GO:0045275	Component	Respiratory chain complex III	IEA
GO:0045333	Process	Cellular respiration	NAS	28844695

Other IDs

• MIM: 612080
• HGNC: 29594
• e!Ensembl: ENSG00000164405

Protein

• UniProt ID: O14949
• Protein name: Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C)
• Protein function: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complex
• PDB: 5XTE, 5XTH, 5XTI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02939	UcrQ	4 → 79	UcrQ family	Family

• Sequence:

  MGREFGNLTRMRHVISYSLSPFEQRAYPHVFTKGIPNVLRRIRESFFRVVPQFVVFYLIY
  TWGTEEFERSKRKNPAAYENDK

• Sequence length: 82

Pathways

KEGG:

Oxidative phosphorylation
Metabolic pathways
Cardiac muscle contraction
Thermogenesis
Non-alcoholic fatty liver disease
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy

Reactome:

Respiratory electron transport

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
LEIGH SYNDROME	—	ClinGen	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY	—	CTD, Disgenet CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mitochondrial complex III deficiency nuclear type 1	Likely benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mitochondrial complex III deficiency nuclear type 4	Uncertain significance; Conflicting classifications of pathogenicity; Likely benign; Benign	ClinVar ClinVar, GenCC	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 1	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 4	—	Disgenet, HPO Disgenet, HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UQCRQ-related disorder	Conflicting classifications of pathogenicity; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	24369324	Associate	★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	28697555		★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hepatitis C Chronic	Hepatitis c	Pubtator	24369324	Stimulate	★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington disease	Pubtator	32302684	Associate	★☆☆☆☆ Found in Text Mining only
Hypoglycemia	Hypoglycemia	BEFREE	12709789		★☆☆☆☆ Found in Text Mining only
Isolated complex III deficiency	Isolated Complex III Deficiency	Orphanet			★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Kidney disease	Pubtator	35341793	Associate	★☆☆☆☆ Found in Text Mining only
Leigh Disease	Leigh Syndrome	CLINGEN_DG	18439546, 25613900		★☆☆☆☆ Found in Text Mining only
LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY	Leigh Syndrome	CLINGEN_DG	18439546, 25613900		★☆☆☆☆ Found in Text Mining only
Leigh Syndrome Due To Mitochondrial Complex II Deficiency	Leigh Syndrome	CLINGEN_DG	18439546, 25613900		★☆☆☆☆ Found in Text Mining only
Leigh Syndrome due to Mitochondrial Complex III Deficiency	Leigh Syndrome	CLINGEN_DG	18439546, 25613900		★☆☆☆☆ Found in Text Mining only
Leigh Syndrome due to Mitochondrial Complex IV Deficiency	Leigh Syndrome	CLINGEN_DG	18439546, 25613900		★☆☆☆☆ Found in Text Mining only
Leigh Syndrome due to Mitochondrial Complex V Deficiency	Leigh Syndrome	CLINGEN_DG	18439546, 25613900		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	17317821, 24369324		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	28697555		★☆☆☆☆ Found in Text Mining only
Mitochondrial Complex III Deficiency	Mitochondrial complex deficiency	Pubtator	18439546	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY (disorder)	Mitochondrial Complex Deficiency	BEFREE	18439546		★☆☆☆☆ Found in Text Mining only
MITOCHONDRIAL COMPLEX III DEFICIENCY (disorder)	Mitochondrial Complex Deficiency	CTD_human_DG			★☆☆☆☆ Found in Text Mining only
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 4	Mitochondrial Complex Deficiency	GENOMICS_ENGLAND_DG	18439546, 27604308		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 4	Mitochondrial Complex Deficiency	UNIPROT_DG	18439546		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 4	Mitochondrial Complex Deficiency	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Necrotizing encephalopathy, infantile subacute, of Leigh	Necrotizing encephalomyelopathy	CLINGEN_DG	18439546, 25613900		★☆☆☆☆ Found in Text Mining only
Severe intellectual disability	Mental retardation	HPO_DG			★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	32757436	Associate	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	26103053	Associate	★☆☆☆☆ Found in Text Mining only