GPR160 (G protein-coupled receptor 160)

Gene

• Entrez ID: 26996
• Gene name: G protein-coupled receptor 160
• Gene symbol: GPR160
• Synonyms (NCBI Gene): GPCR1, GPCR150
• Chromosome: 3
• Chromosome location: 3q26.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1030829	hsa-miR-2053	CLIP-seq
MIRT1030830	hsa-miR-2113	CLIP-seq
MIRT1030831	hsa-miR-3152-3p	CLIP-seq
MIRT1030832	hsa-miR-3673	CLIP-seq
MIRT1030833	hsa-miR-3973	CLIP-seq
MIRT1030834	hsa-miR-432	CLIP-seq
MIRT1030835	hsa-miR-495	CLIP-seq
MIRT1030836	hsa-miR-548a-5p	CLIP-seq
MIRT1030837	hsa-miR-548ab	CLIP-seq
MIRT1030838	hsa-miR-548ak	CLIP-seq
MIRT1030839	hsa-miR-548b-5p	CLIP-seq
MIRT1030840	hsa-miR-548c-5p	CLIP-seq
MIRT1030841	hsa-miR-548d-5p	CLIP-seq
MIRT1030842	hsa-miR-548h	CLIP-seq
MIRT1030843	hsa-miR-548i	CLIP-seq
MIRT1030844	hsa-miR-548j	CLIP-seq
MIRT1030845	hsa-miR-548w	CLIP-seq
MIRT1030846	hsa-miR-548y	CLIP-seq
MIRT1030847	hsa-miR-559	CLIP-seq
MIRT1030848	hsa-miR-569	CLIP-seq
MIRT1030849	hsa-miR-599	CLIP-seq
MIRT1030850	hsa-miR-944	CLIP-seq
MIRT2005822	hsa-miR-1244	CLIP-seq
MIRT2005823	hsa-miR-129-5p	CLIP-seq
MIRT2005824	hsa-miR-3651	CLIP-seq
MIRT2005825	hsa-miR-802	CLIP-seq
MIRT2005823	hsa-miR-129-5p	CLIP-seq
MIRT2238428	hsa-miR-203	CLIP-seq
MIRT2238429	hsa-miR-4704-3p	CLIP-seq
MIRT2238430	hsa-miR-4766-5p	CLIP-seq
MIRT2005825	hsa-miR-802	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0016020	Component	Membrane	IEA
GO:0043235	Component	Receptor complex	IBA
GO:0043235	Component	Receptor complex	IDA	23382219

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9UJ42
• Protein name: Probable G-protein coupled receptor 160 (G-protein coupled receptor GPCR1) (hGPCR1)
• Protein function: Orphan receptor.
• Sequence:

  MTALSSENCSFQYQLRQTNQPLDVNYLLFLIILGKILLNILTLGMRRKNTCQNFMEYFCI
  SLAFVDLLLLVNISIILYFRDFVLLSIRFTKYHICLFTQIISFTYGFLHYPVFLTACIDY
  CLNFSKTTKLSFKCQKLFYFFTVILIWISVLAYVLGDPAIYQSLKAQNAYSRHCPFYVSI
  QSYWLSFFMVMILFVAFITCWEEVTTLVQAIRITSYMNETILYFPFSSHSSYTVRSKKIF
  LSKLIVCFLSTWLPFVLLQVIIVLLKVQIPAYIEMNIPWLYFVNSFLIATVYWFNCHKLN
  LKDIGLPLDPFVNWKCCFIPLTIPNLEQIEKPISIMIC

• Sequence length: 338

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
GPR160-related disorder	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TESTICULAR CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TESTICULAR GERM CELL TUMOR	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Chronic eosinophilic leukemia	Eosinophilic Leukemia	BEFREE	7646814		★☆☆☆☆ Found in Text Mining only
Eosinophilic leukemia	Eosinophilic Leukemia	BEFREE	7646814		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	35771163	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	15313197		★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	GWASDB_DG	21211798		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	15313197		★☆☆☆☆ Found in Text Mining only
Prostatic Hyperplasia	Prostatic hyperplasia	Pubtator	37781794	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	37781794	Associate	★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	GWASCAT_DG	25854761		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Testicular Germ Cell Tumor	Testicular Germ Cell Tumor	GWASCAT_DG	28604732		★★☆☆☆ Found in Text Mining + Unknown/Other Associations