Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	266812
Gene name	Nucleosome assembly protein 1 like 5
Gene symbol	NAP1L5
Synonyms (NCBI Gene)	DRLM
Chromosome	4
Chromosome location	4q22.1\|4q21-q22
Summary	This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a

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miRTarBase ID	miRNA	Experiments	Reference
MIRT440151	hsa-miR-381-3p	HITS-CLIP	24374217
MIRT440151	hsa-miR-381-3p	HITS-CLIP	24374217
MIRT1173737	hsa-miR-1236	CLIP-seq
MIRT1173738	hsa-miR-1253	CLIP-seq
MIRT1173739	hsa-miR-1297	CLIP-seq
MIRT1173740	hsa-miR-26a	CLIP-seq
MIRT1173741	hsa-miR-26b	CLIP-seq
MIRT1173742	hsa-miR-3148	CLIP-seq
MIRT1173743	hsa-miR-3153	CLIP-seq
MIRT1173744	hsa-miR-3192	CLIP-seq
MIRT1173745	hsa-miR-3609	CLIP-seq
MIRT1173746	hsa-miR-3919	CLIP-seq
MIRT1173747	hsa-miR-3973	CLIP-seq
MIRT1173748	hsa-miR-4263	CLIP-seq
MIRT1173749	hsa-miR-4314	CLIP-seq
MIRT1173750	hsa-miR-4465	CLIP-seq
MIRT1173751	hsa-miR-4506	CLIP-seq
MIRT1173752	hsa-miR-4646-5p	CLIP-seq
MIRT1173753	hsa-miR-4668-5p	CLIP-seq
MIRT1173754	hsa-miR-4756-3p	CLIP-seq
MIRT1173755	hsa-miR-4778-5p	CLIP-seq
MIRT1173756	hsa-miR-4786-5p	CLIP-seq
MIRT1173757	hsa-miR-520g	CLIP-seq
MIRT1173758	hsa-miR-520h	CLIP-seq
MIRT1173759	hsa-miR-548aa	CLIP-seq
MIRT1173760	hsa-miR-548ah	CLIP-seq
MIRT1173761	hsa-miR-576-5p	CLIP-seq
MIRT1173762	hsa-miR-607	CLIP-seq
MIRT1173763	hsa-miR-629	CLIP-seq
MIRT1173764	hsa-miR-889	CLIP-seq
MIRT2050312	hsa-miR-4684-5p	CLIP-seq
MIRT2050313	hsa-miR-4716-5p	CLIP-seq
MIRT2050314	hsa-miR-4760-3p	CLIP-seq
MIRT2050315	hsa-miR-4768-5p	CLIP-seq
MIRT2050316	hsa-miR-4799-5p	CLIP-seq
MIRT2279293	hsa-miR-203	CLIP-seq
MIRT2279294	hsa-miR-3130-3p	CLIP-seq
MIRT2279295	hsa-miR-3940-5p	CLIP-seq
MIRT2279296	hsa-miR-4297	CLIP-seq
MIRT2279297	hsa-miR-4328	CLIP-seq
MIRT2279298	hsa-miR-4477a	CLIP-seq
MIRT2279299	hsa-miR-4503	CLIP-seq
MIRT2279300	hsa-miR-4507	CLIP-seq
MIRT2279301	hsa-miR-4727-5p	CLIP-seq
MIRT2279302	hsa-miR-4789-3p	CLIP-seq
MIRT2279303	hsa-miR-4793-3p	CLIP-seq
MIRT2279304	hsa-miR-942	CLIP-seq
MIRT2438844	hsa-miR-1323	CLIP-seq
MIRT2438845	hsa-miR-323-3p	CLIP-seq
MIRT2438846	hsa-miR-377	CLIP-seq
MIRT2050314	hsa-miR-4760-3p	CLIP-seq
MIRT2279302	hsa-miR-4789-3p	CLIP-seq
MIRT2438847	hsa-miR-548o	CLIP-seq
MIRT2438848	hsa-miR-924	CLIP-seq
MIRT1173738	hsa-miR-1253	CLIP-seq
MIRT2454848	hsa-miR-30a	CLIP-seq
MIRT2454849	hsa-miR-30b	CLIP-seq
MIRT2454850	hsa-miR-30c	CLIP-seq
MIRT2454851	hsa-miR-30d	CLIP-seq
MIRT2454852	hsa-miR-30e	CLIP-seq
MIRT1173746	hsa-miR-3919	CLIP-seq
MIRT1173754	hsa-miR-4756-3p	CLIP-seq
MIRT1173738	hsa-miR-1253	CLIP-seq
MIRT2577427	hsa-miR-1287	CLIP-seq
MIRT2438844	hsa-miR-1323	CLIP-seq
MIRT2454848	hsa-miR-30a	CLIP-seq
MIRT2454849	hsa-miR-30b	CLIP-seq
MIRT2454850	hsa-miR-30c	CLIP-seq
MIRT2454851	hsa-miR-30d	CLIP-seq
MIRT2454852	hsa-miR-30e	CLIP-seq
MIRT2577428	hsa-miR-3591-3p	CLIP-seq
MIRT2438846	hsa-miR-377	CLIP-seq
MIRT1173746	hsa-miR-3919	CLIP-seq
MIRT1173747	hsa-miR-3973	CLIP-seq
MIRT2577429	hsa-miR-4643	CLIP-seq
MIRT2577430	hsa-miR-466	CLIP-seq
MIRT1173754	hsa-miR-4756-3p	CLIP-seq
MIRT2050314	hsa-miR-4760-3p	CLIP-seq
MIRT2577431	hsa-miR-4775	CLIP-seq
MIRT1173756	hsa-miR-4786-5p	CLIP-seq
MIRT2279302	hsa-miR-4789-3p	CLIP-seq
MIRT2577432	hsa-miR-4803	CLIP-seq
MIRT2577433	hsa-miR-548k	CLIP-seq
MIRT2438847	hsa-miR-548o	CLIP-seq
MIRT2577434	hsa-miR-570	CLIP-seq
MIRT2577435	hsa-miR-590-3p	CLIP-seq
MIRT2577436	hsa-miR-591	CLIP-seq
MIRT2685795	hsa-miR-1183	CLIP-seq
MIRT1173738	hsa-miR-1253	CLIP-seq
MIRT2577427	hsa-miR-1287	CLIP-seq
MIRT2438844	hsa-miR-1323	CLIP-seq
MIRT2454848	hsa-miR-30a	CLIP-seq
MIRT2454849	hsa-miR-30b	CLIP-seq
MIRT2454850	hsa-miR-30c	CLIP-seq
MIRT2454851	hsa-miR-30d	CLIP-seq
MIRT2454852	hsa-miR-30e	CLIP-seq
MIRT2438845	hsa-miR-323-3p	CLIP-seq
MIRT2577428	hsa-miR-3591-3p	CLIP-seq
MIRT2438846	hsa-miR-377	CLIP-seq
MIRT2685796	hsa-miR-3909	CLIP-seq
MIRT1173746	hsa-miR-3919	CLIP-seq
MIRT2279295	hsa-miR-3940-5p	CLIP-seq
MIRT1173747	hsa-miR-3973	CLIP-seq
MIRT2279297	hsa-miR-4328	CLIP-seq
MIRT2685797	hsa-miR-4457	CLIP-seq
MIRT2279300	hsa-miR-4507	CLIP-seq
MIRT2577429	hsa-miR-4643	CLIP-seq
MIRT2577430	hsa-miR-466	CLIP-seq
MIRT2685798	hsa-miR-4668-3p	CLIP-seq
MIRT2685799	hsa-miR-4693-5p	CLIP-seq
MIRT1173754	hsa-miR-4756-3p	CLIP-seq
MIRT2050314	hsa-miR-4760-3p	CLIP-seq
MIRT2577431	hsa-miR-4775	CLIP-seq
MIRT1173756	hsa-miR-4786-5p	CLIP-seq
MIRT2279302	hsa-miR-4789-3p	CLIP-seq
MIRT2577432	hsa-miR-4803	CLIP-seq
MIRT2685800	hsa-miR-500a	CLIP-seq
MIRT2685801	hsa-miR-513b	CLIP-seq
MIRT2685802	hsa-miR-524-3p	CLIP-seq
MIRT2685803	hsa-miR-525-3p	CLIP-seq
MIRT2685804	hsa-miR-548c-3p	CLIP-seq
MIRT2577433	hsa-miR-548k	CLIP-seq
MIRT2438847	hsa-miR-548o	CLIP-seq
MIRT2577434	hsa-miR-570	CLIP-seq
MIRT2685805	hsa-miR-586	CLIP-seq
MIRT2577435	hsa-miR-590-3p	CLIP-seq
MIRT2577436	hsa-miR-591	CLIP-seq
MIRT1173763	hsa-miR-629	CLIP-seq
MIRT2438848	hsa-miR-924	CLIP-seq

Show/Hide all (3)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0006334	Process	Nucleosome assembly	IEA

MIM	HGNC	e!Ensembl
612203	19968	ENSG00000177432

Q96NT1

Protein name

Nucleosome assembly protein 1-like 5 (Down-regulated in liver malignancy)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00956	NAP	79 → 175	Nucleosome assembly protein (NAP)	Family

Tissue specificity

TISSUE SPECIFICITY: Predominantly expressed in brain. {ECO:0000269|PubMed:12383514}.

Sequence

MADSENQGPAEPSQAAAAAEAAAEEVMAEGGAQGGDCDSAAGDPDSAAGQMAEEPQTPAE
NAPKPKNDFIESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKPLLAKI
QELTGEMEGCAWTLEGEEEEEEEYEDDEEEGEDEEEEEAAAEAAAGAKHDDAHAEMPDDA
KK

Sequence length

182

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Breast Neoplasms	Breast neoplasm	Pubtator	36689360	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	36374212	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Heart Defects Congenital	Congenital heart defect	Pubtator	33407475	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	12383514		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	20622171		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	20622171	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

NAP1L5 (nucleosome assembly protein 1 like 5)