Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	26512
Gene name	Integrator complex subunit 6
Gene symbol	INTS6
Synonyms (NCBI Gene)	DBI-1DDX26DDX26ADICE1HDBINT6Notchl2
Chromosome	13
Chromosome location	13q14.3
Summary	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is inv

240

Show/Hide all (240)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020710	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT023673	hsa-miR-1-3p	Proteomics	18668040
MIRT028529	hsa-miR-30a-5p	Proteomics	18668040
MIRT442153	hsa-miR-95-5p	PAR-CLIP	22100165
MIRT442152	hsa-miR-4317	PAR-CLIP	22100165
MIRT442151	hsa-miR-616-3p	PAR-CLIP	22100165
MIRT442150	hsa-miR-4662a-5p	PAR-CLIP	22100165
MIRT442149	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT440440	ebv-miR-BART13-3p	HITS-CLIP	22473208
MIRT440440	ebv-miR-BART13-3p	HITS-CLIP	22473208
MIRT442153	hsa-miR-95-5p	PAR-CLIP	22100165
MIRT442152	hsa-miR-4317	PAR-CLIP	22100165
MIRT442151	hsa-miR-616-3p	PAR-CLIP	22100165
MIRT442150	hsa-miR-4662a-5p	PAR-CLIP	22100165
MIRT442149	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT1068103	hsa-miR-106a	CLIP-seq
MIRT1068104	hsa-miR-106b	CLIP-seq
MIRT1068105	hsa-miR-1208	CLIP-seq
MIRT1068106	hsa-miR-1245	CLIP-seq
MIRT1068107	hsa-miR-1297	CLIP-seq
MIRT1068108	hsa-miR-17	CLIP-seq
MIRT1068109	hsa-miR-20a	CLIP-seq
MIRT1068110	hsa-miR-20b	CLIP-seq
MIRT1068111	hsa-miR-2117	CLIP-seq
MIRT1068112	hsa-miR-26a	CLIP-seq
MIRT1068113	hsa-miR-26b	CLIP-seq
MIRT1068114	hsa-miR-302a	CLIP-seq
MIRT1068115	hsa-miR-302b	CLIP-seq
MIRT1068116	hsa-miR-302c	CLIP-seq
MIRT1068117	hsa-miR-302d	CLIP-seq
MIRT1068118	hsa-miR-302e	CLIP-seq
MIRT1068119	hsa-miR-3120-5p	CLIP-seq
MIRT1068120	hsa-miR-3121-3p	CLIP-seq
MIRT1068121	hsa-miR-3134	CLIP-seq
MIRT1068122	hsa-miR-3140-3p	CLIP-seq
MIRT1068123	hsa-miR-3149	CLIP-seq
MIRT1068124	hsa-miR-3174	CLIP-seq
MIRT1068125	hsa-miR-3185	CLIP-seq
MIRT1068126	hsa-miR-338-5p	CLIP-seq
MIRT1068127	hsa-miR-3606	CLIP-seq
MIRT1068128	hsa-miR-3607-3p	CLIP-seq
MIRT1068129	hsa-miR-3646	CLIP-seq
MIRT1068130	hsa-miR-3662	CLIP-seq
MIRT1068131	hsa-miR-3673	CLIP-seq
MIRT1068132	hsa-miR-3677-5p	CLIP-seq
MIRT1068133	hsa-miR-372	CLIP-seq
MIRT1068134	hsa-miR-373	CLIP-seq
MIRT1068135	hsa-miR-3974	CLIP-seq
MIRT1068136	hsa-miR-4273	CLIP-seq
MIRT1068137	hsa-miR-4465	CLIP-seq
MIRT1068138	hsa-miR-4519	CLIP-seq
MIRT1068139	hsa-miR-4534	CLIP-seq
MIRT1068140	hsa-miR-4662a-3p	CLIP-seq
MIRT1068141	hsa-miR-4698	CLIP-seq
MIRT1068142	hsa-miR-4699-3p	CLIP-seq
MIRT1068143	hsa-miR-4701-5p	CLIP-seq
MIRT1068144	hsa-miR-4709-3p	CLIP-seq
MIRT1068145	hsa-miR-4710	CLIP-seq
MIRT1068146	hsa-miR-4765	CLIP-seq
MIRT1068147	hsa-miR-4790-3p	CLIP-seq
MIRT1068148	hsa-miR-4792	CLIP-seq
MIRT1068149	hsa-miR-4804-3p	CLIP-seq
MIRT1068150	hsa-miR-495	CLIP-seq
MIRT1068151	hsa-miR-515-5p	CLIP-seq
MIRT1068152	hsa-miR-519a	CLIP-seq
MIRT1068153	hsa-miR-519b-3p	CLIP-seq
MIRT1068154	hsa-miR-519c-3p	CLIP-seq
MIRT1068155	hsa-miR-519d	CLIP-seq
MIRT1068156	hsa-miR-520a-3p	CLIP-seq
MIRT1068157	hsa-miR-520b	CLIP-seq
MIRT1068158	hsa-miR-520c-3p	CLIP-seq
MIRT1068159	hsa-miR-520d-3p	CLIP-seq
MIRT1068160	hsa-miR-520e	CLIP-seq
MIRT1068161	hsa-miR-520f	CLIP-seq
MIRT1068162	hsa-miR-548a-5p	CLIP-seq
MIRT1068163	hsa-miR-548ab	CLIP-seq
MIRT1068164	hsa-miR-548ak	CLIP-seq
MIRT1068165	hsa-miR-548b-5p	CLIP-seq
MIRT1068166	hsa-miR-548c-3p	CLIP-seq
MIRT1068167	hsa-miR-548c-5p	CLIP-seq
MIRT1068168	hsa-miR-548d-5p	CLIP-seq
MIRT1068169	hsa-miR-548h	CLIP-seq
MIRT1068170	hsa-miR-548i	CLIP-seq
MIRT1068171	hsa-miR-548j	CLIP-seq
MIRT1068172	hsa-miR-548k	CLIP-seq
MIRT1068173	hsa-miR-548l	CLIP-seq
MIRT1068174	hsa-miR-548t	CLIP-seq
MIRT1068175	hsa-miR-548w	CLIP-seq
MIRT1068176	hsa-miR-548y	CLIP-seq
MIRT1068177	hsa-miR-559	CLIP-seq
MIRT1068178	hsa-miR-588	CLIP-seq
MIRT1068179	hsa-miR-643	CLIP-seq
MIRT1068180	hsa-miR-93	CLIP-seq
MIRT1068181	hsa-miR-129-5p	CLIP-seq
MIRT1068182	hsa-miR-182	CLIP-seq
MIRT1068183	hsa-miR-21	CLIP-seq
MIRT1068184	hsa-miR-30a	CLIP-seq
MIRT1068185	hsa-miR-30b	CLIP-seq
MIRT1068186	hsa-miR-30c	CLIP-seq
MIRT1068187	hsa-miR-30d	CLIP-seq
MIRT1068188	hsa-miR-30e	CLIP-seq
MIRT1068189	hsa-miR-31	CLIP-seq
MIRT1068120	hsa-miR-3121-3p	CLIP-seq
MIRT1068190	hsa-miR-3126-5p	CLIP-seq
MIRT1068191	hsa-miR-3130-3p	CLIP-seq
MIRT1068121	hsa-miR-3134	CLIP-seq
MIRT1068192	hsa-miR-3137	CLIP-seq
MIRT1068193	hsa-miR-3148	CLIP-seq
MIRT1068194	hsa-miR-340	CLIP-seq
MIRT1068130	hsa-miR-3662	CLIP-seq
MIRT1068195	hsa-miR-3671	CLIP-seq
MIRT1068196	hsa-miR-3688-3p	CLIP-seq
MIRT1068197	hsa-miR-3689a-3p	CLIP-seq
MIRT1068198	hsa-miR-3689c	CLIP-seq
MIRT1068199	hsa-miR-3935	CLIP-seq
MIRT1068200	hsa-miR-3973	CLIP-seq
MIRT1068201	hsa-miR-4275	CLIP-seq
MIRT1068202	hsa-miR-4419a	CLIP-seq
MIRT1068203	hsa-miR-4510	CLIP-seq
MIRT1068139	hsa-miR-4534	CLIP-seq
MIRT1068204	hsa-miR-4709-5p	CLIP-seq
MIRT1068205	hsa-miR-4724-3p	CLIP-seq
MIRT1068206	hsa-miR-4762-5p	CLIP-seq
MIRT1068207	hsa-miR-4793-3p	CLIP-seq
MIRT1068208	hsa-miR-4797-5p	CLIP-seq
MIRT1068209	hsa-miR-520d-5p	CLIP-seq
MIRT1068210	hsa-miR-524-5p	CLIP-seq
MIRT1068211	hsa-miR-539	CLIP-seq
MIRT1068212	hsa-miR-544b	CLIP-seq
MIRT1068162	hsa-miR-548a-5p	CLIP-seq
MIRT1068163	hsa-miR-548ab	CLIP-seq
MIRT1068164	hsa-miR-548ak	CLIP-seq
MIRT1068165	hsa-miR-548b-5p	CLIP-seq
MIRT1068167	hsa-miR-548c-5p	CLIP-seq
MIRT1068168	hsa-miR-548d-5p	CLIP-seq
MIRT1068169	hsa-miR-548h	CLIP-seq
MIRT1068170	hsa-miR-548i	CLIP-seq
MIRT1068171	hsa-miR-548j	CLIP-seq
MIRT1068213	hsa-miR-548m	CLIP-seq
MIRT1068175	hsa-miR-548w	CLIP-seq
MIRT1068176	hsa-miR-548y	CLIP-seq
MIRT1068177	hsa-miR-559	CLIP-seq
MIRT1068214	hsa-miR-587	CLIP-seq
MIRT1068215	hsa-miR-590-5p	CLIP-seq
MIRT1068216	hsa-miR-595	CLIP-seq
MIRT1068217	hsa-miR-605	CLIP-seq
MIRT1068218	hsa-miR-607	CLIP-seq
MIRT2016602	hsa-miR-1183	CLIP-seq
MIRT2016603	hsa-miR-124	CLIP-seq
MIRT1068106	hsa-miR-1245	CLIP-seq
MIRT2016604	hsa-miR-1271	CLIP-seq
MIRT1068181	hsa-miR-129-5p	CLIP-seq
MIRT1068182	hsa-miR-182	CLIP-seq
MIRT2016605	hsa-miR-200b	CLIP-seq
MIRT2016606	hsa-miR-200c	CLIP-seq
MIRT2016607	hsa-miR-2053	CLIP-seq
MIRT2016608	hsa-miR-3145-3p	CLIP-seq
MIRT2016609	hsa-miR-3200-5p	CLIP-seq
MIRT2016610	hsa-miR-3942-3p	CLIP-seq
MIRT2016611	hsa-miR-429	CLIP-seq
MIRT2016612	hsa-miR-4470	CLIP-seq
MIRT2016613	hsa-miR-4477b	CLIP-seq
MIRT2016614	hsa-miR-4496	CLIP-seq
MIRT1068138	hsa-miR-4519	CLIP-seq
MIRT2016615	hsa-miR-4773	CLIP-seq
MIRT2016616	hsa-miR-506	CLIP-seq
MIRT2016617	hsa-miR-548an	CLIP-seq
MIRT2016618	hsa-miR-579	CLIP-seq
MIRT2016619	hsa-miR-96	CLIP-seq
MIRT2016602	hsa-miR-1183	CLIP-seq
MIRT2248762	hsa-miR-2278	CLIP-seq
MIRT2248763	hsa-miR-3145-5p	CLIP-seq
MIRT2248764	hsa-miR-34c-3p	CLIP-seq
MIRT1068129	hsa-miR-3646	CLIP-seq
MIRT2248765	hsa-miR-4468	CLIP-seq
MIRT2016615	hsa-miR-4773	CLIP-seq
MIRT2248766	hsa-miR-508-5p	CLIP-seq
MIRT2248767	hsa-miR-517a	CLIP-seq
MIRT2248768	hsa-miR-517c	CLIP-seq
MIRT1068209	hsa-miR-520d-5p	CLIP-seq
MIRT1068210	hsa-miR-524-5p	CLIP-seq
MIRT2248769	hsa-miR-922	CLIP-seq
MIRT2389441	hsa-miR-1269	CLIP-seq
MIRT2389442	hsa-miR-1269b	CLIP-seq
MIRT2016609	hsa-miR-3200-5p	CLIP-seq
MIRT2016607	hsa-miR-2053	CLIP-seq
MIRT1068120	hsa-miR-3121-3p	CLIP-seq
MIRT2552376	hsa-miR-3171	CLIP-seq
MIRT1068130	hsa-miR-3662	CLIP-seq
MIRT2552377	hsa-miR-4443	CLIP-seq
MIRT2552378	hsa-miR-4495	CLIP-seq
MIRT2552379	hsa-miR-451b	CLIP-seq
MIRT2552380	hsa-miR-4668-3p	CLIP-seq
MIRT1068152	hsa-miR-519a	CLIP-seq
MIRT1068153	hsa-miR-519b-3p	CLIP-seq
MIRT1068154	hsa-miR-519c-3p	CLIP-seq
MIRT1068162	hsa-miR-548a-5p	CLIP-seq
MIRT1068163	hsa-miR-548ab	CLIP-seq
MIRT1068164	hsa-miR-548ak	CLIP-seq
MIRT1068165	hsa-miR-548b-5p	CLIP-seq
MIRT1068166	hsa-miR-548c-3p	CLIP-seq
MIRT1068167	hsa-miR-548c-5p	CLIP-seq
MIRT1068168	hsa-miR-548d-5p	CLIP-seq
MIRT1068169	hsa-miR-548h	CLIP-seq
MIRT1068170	hsa-miR-548i	CLIP-seq
MIRT1068171	hsa-miR-548j	CLIP-seq
MIRT1068172	hsa-miR-548k	CLIP-seq
MIRT1068173	hsa-miR-548l	CLIP-seq
MIRT1068213	hsa-miR-548m	CLIP-seq
MIRT1068175	hsa-miR-548w	CLIP-seq
MIRT1068176	hsa-miR-548y	CLIP-seq
MIRT1068177	hsa-miR-559	CLIP-seq
MIRT1068214	hsa-miR-587	CLIP-seq
MIRT2552381	hsa-miR-765	CLIP-seq
MIRT1068120	hsa-miR-3121-3p	CLIP-seq
MIRT2552376	hsa-miR-3171	CLIP-seq
MIRT1068130	hsa-miR-3662	CLIP-seq
MIRT2552378	hsa-miR-4495	CLIP-seq
MIRT2552380	hsa-miR-4668-3p	CLIP-seq
MIRT2682857	hsa-miR-500a	CLIP-seq
MIRT1068152	hsa-miR-519a	CLIP-seq
MIRT1068153	hsa-miR-519b-3p	CLIP-seq
MIRT1068154	hsa-miR-519c-3p	CLIP-seq
MIRT1068162	hsa-miR-548a-5p	CLIP-seq
MIRT1068163	hsa-miR-548ab	CLIP-seq
MIRT1068164	hsa-miR-548ak	CLIP-seq
MIRT1068165	hsa-miR-548b-5p	CLIP-seq
MIRT1068166	hsa-miR-548c-3p	CLIP-seq
MIRT1068167	hsa-miR-548c-5p	CLIP-seq
MIRT1068168	hsa-miR-548d-5p	CLIP-seq
MIRT1068169	hsa-miR-548h	CLIP-seq
MIRT1068170	hsa-miR-548i	CLIP-seq
MIRT1068171	hsa-miR-548j	CLIP-seq
MIRT1068172	hsa-miR-548k	CLIP-seq
MIRT1068173	hsa-miR-548l	CLIP-seq
MIRT1068213	hsa-miR-548m	CLIP-seq
MIRT1068175	hsa-miR-548w	CLIP-seq
MIRT1068176	hsa-miR-548y	CLIP-seq
MIRT1068177	hsa-miR-559	CLIP-seq
MIRT1068214	hsa-miR-587	CLIP-seq

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IDA	34004147
GO:0004888	Function	Transmembrane signaling receptor activity	TAS	10467397
GO:0005515	Function	Protein binding	IPI	16239144
GO:0005634	Component	Nucleus	IDA	34004147, 39032490
GO:0005634	Component	Nucleus	IDA	23904267
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	32647223
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0006366	Process	Transcription by RNA polymerase II	IDA	9852112
GO:0006368	Process	Transcription elongation by RNA polymerase II	IDA	9852112
GO:0015629	Component	Actin cytoskeleton	IDA
GO:0016180	Process	SnRNA processing	IDA	16239144
GO:0016180	Process	SnRNA processing	NAS	16239144
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	33243860, 34004147
GO:0032039	Component	Integrator complex	IBA
GO:0032039	Component	Integrator complex	IDA	16239144, 36920904, 39032490
GO:0032039	Component	Integrator complex	NAS	33548203
GO:0034243	Process	Regulation of transcription elongation by RNA polymerase II	NAS	32697989
GO:0034472	Process	SnRNA 3'-end processing	IBA
GO:0071168	Process	Protein localization to chromatin	IDA	34004147
GO:0160232	Component	INTAC complex	IDA	33243860, 34004147, 34762484, 36869814, 38570683
GO:0160240	Process	RNA polymerase II transcription initiation surveillance	IDA	33243860, 34004147, 38570683, 39504960

MIM	HGNC	e!Ensembl
604331	14879	ENSG00000102786

Q9UL03

Protein name

Integrator complex subunit 6 (Int6) (DBI-1) (Protein deleted in cancer 1) (DICE1)

Protein function

Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:33243860, PubMed:34004147, PubMed:39504960). The integrator complex provides a

PDB

7BV7 , 7CUN , 7PKS , 7YCX , 8RBX , 8RBZ , 8RC4 , 8YJB

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13519	VWA_2	4 → 132	von Willebrand factor type A domain	Domain
PF15300	INT_SG_DDX_CT_C	807 → 869	INTS6/SAGE1/DDX26B/CT45 C-terminus	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10467397}.

Sequence

MPILLFLIDTSASMNQRSHLGTTYLDTAKGAVETFMKLRARDPASRGDRYMLVTFEEPPY
AIKAGWKENHATFMNELKNLQAEGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFL
EPAIIITITDGSKLTTTSGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGTMS
VESEQLTGVPLDDSAITPMCEVTGGRSYSVCSPRMLNQCLESLVQKVQSGVVINFEKAGP
DPSPVEDGQPDISRPFGSQPWHSCHKLIYVRPNPKTGVPIGHWPVPESFWPDQNSPTLPP
RTSHPVVKFSCTDCEPMVIDKLPFDKYELEPSPLTQFILERKSPQTCWQVYVSNSAKYSE
LGHPFGYLKASTALNCVNLFVMPYNYPVLLPLLDDLFKVHKAKPTLKWRQSFESYLKTMP
PYYLGPLKKAVRMMGAPNLIADSMEYGLSYSVISYLKKLSQQAKIESDRVIGSVGKKVVQ
ETGIKVRSRSHGLSMAYRKDFQQLLQGISEDVPHRLLDLNMKEYTGFQVALLNKDLKPQT
FRNAYDIPRRNLLDHLTRMRSNLLKSTRRFLKGQDEDQVHSVPIAQMGNYQEYLKQVPSP
LRELDPDQPRRLHTFGNPFKLDKKGMMIDEADEFVAGPQNKHKRPGEPNMQGIPKRRRCM
SPLLRGRQQNPVVNNHIGGKGPPAPTTQAQPDLIKPLPLHKISETTNDSIIHDVVENHVA
DQLSSDITPNAMDTEFSASSPASLLERPTNHMEALGHDHLGTNDLTVGGFLENHEEPRDK
EQCAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGS
LQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN

Sequence length

887

Interactions

View interactions

	Reactome
			RNA polymerase II transcribes snRNA genes

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Autism spectrum disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTS6-related disorder	Uncertain significance; Likely benign; Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (25)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma	Adenocarcinoma	BEFREE	11115556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenoma of large intestine	Colorectal adenoma	BEFREE	11751426		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Ischemia	Cerebral Ischemia	BEFREE	17324924, 20713899, 22960363		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	11115556, 17187232, 17626637, 20453879, 22907435, 25499975, 27550454, 30165191, 9403073		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	10467397, 11115556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	28899352	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	BEFREE	17385060		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	10360675, 35247917	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Eclampsia	Eclampsia	BEFREE	29895936		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	24481065		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25686840, 28899352		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	11115556		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	11115556, 17187232, 20453879, 22907435, 25499975, 27550454, 30165191		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	16007164, 25660097		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	11115556, 15030549, 17324924, 20453879, 27550454, 28899352		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	11115556, 17324924, 9403073		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	23280823		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	10467397, 11115556, 11939413, 12527901, 15867213, 16007164, 17187232, 17324924, 17626637, 20735817, 22907435, 22960363, 25660097, 25686840, 27814599 View all (5 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	9694872		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	10467397, 11115556, 15867213		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	16007164, 25660097		★★★★★ ★☆☆☆☆ Found in Text Mining only
Retinoblastoma	Retinoblastoma	BEFREE	7689221, 8125309, 9694872		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	12527901		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	29987267	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Testicular Germ Cell Tumor	Testicular germ cell tumor	Pubtator	17167184	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only

INTS6 (integrator complex subunit 6)