RSL1D1 (ribosomal L1 domain containing 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 26156 |
| Gene name | Ribosomal L1 domain containing 1 |
| Gene symbol | RSL1D1 |
| Synonyms (NCBI Gene) |
CSIGL12PBK1UTP30
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| Chromosome | 16 |
| Chromosome location | 16p13.13 |
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miRNA
miRNA information provided by mirtarbase database.
768
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O76021 | ||||||||||
| Protein name | Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1) | ||||||||||
| Protein function | Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | ||||||||||
| PDB | 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY , 8FKZ , 8FL2 , 8FL6 , 8FLA , 8FLD , 8INE , 8INF , 8IPX , 8IPY , 8IR3 | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed at high intensities in the heart, skeletal muscle, and placenta. {ECO:0000269|PubMed:18678645, ECO:0000269|PubMed:9859858}. | ||||||||||
| Sequence |
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| Sequence length | 490 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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