PHF19 (PHD finger protein 19)

Gene

• Entrez ID: 26147
• Gene name: PHD finger protein 19
• Gene symbol: PHF19
• Synonyms (NCBI Gene): MTF2L1, PCL3, TDRD19B
• Chromosome: 9
• Chromosome location: 9q33.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT002687	hsa-miR-124-3p	Microarray	15685193
MIRT016585	hsa-miR-193b-3p	Microarray	20304954
MIRT002687	hsa-miR-124-3p	Microarray	15685193
MIRT002687	hsa-miR-124-3p	Microarray	18668037
MIRT025582	hsa-miR-34a-5p	Sequencing	20371350
MIRT026902	hsa-miR-192-5p	Microarray	19074876
MIRT027228	hsa-miR-103a-3p	Sequencing	20371350
MIRT027908	hsa-miR-96-5p	Sequencing	20371350
MIRT032068	hsa-miR-16-5p	Sequencing	20371350
MIRT040639	hsa-miR-92b-3p	CLASH	23622248
MIRT655180	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT655179	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT471141	hsa-miR-1470	HITS-CLIP	23824327
MIRT471140	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT655178	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT655177	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT655176	hsa-miR-4469	HITS-CLIP	23824327
MIRT655175	hsa-miR-3166	HITS-CLIP	23824327
MIRT655174	hsa-miR-4771	HITS-CLIP	23824327
MIRT655173	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT655172	hsa-miR-1273h-3p	HITS-CLIP	23824327
MIRT655171	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655170	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655169	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT571829	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT571828	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT571827	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT571825	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT571826	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT032068	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT571824	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT571823	hsa-miR-548ac	PAR-CLIP	20371350
MIRT571822	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT571821	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT571820	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT571819	hsa-miR-548z	PAR-CLIP	20371350
MIRT571818	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT571817	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT571815	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT571816	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT571814	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT571813	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT571812	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT571811	hsa-miR-548aa	PAR-CLIP	20371350
MIRT571810	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT571809	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT571808	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT571807	hsa-miR-4477a	PAR-CLIP	20371350
MIRT506210	hsa-miR-449a	PAR-CLIP	23446348
MIRT025582	hsa-miR-34a-5p	PAR-CLIP	23446348
MIRT506209	hsa-miR-34c-5p	PAR-CLIP	23446348
MIRT506208	hsa-miR-449b-5p	PAR-CLIP	23446348
MIRT506207	hsa-miR-223-3p	PAR-CLIP	23446348
MIRT506206	hsa-miR-3974	PAR-CLIP	23446348
MIRT506205	hsa-miR-5700	PAR-CLIP	23446348
MIRT506204	hsa-miR-4715-5p	PAR-CLIP	23446348
MIRT506203	hsa-miR-3126-3p	PAR-CLIP	23446348
MIRT506202	hsa-miR-1298-3p	PAR-CLIP	23446348
MIRT506201	hsa-miR-4490	PAR-CLIP	23446348
MIRT506200	hsa-miR-4774-5p	PAR-CLIP	23446348
MIRT506199	hsa-miR-4660	PAR-CLIP	23446348
MIRT506198	hsa-miR-548au-3p	PAR-CLIP	23446348
MIRT506197	hsa-miR-1301-3p	PAR-CLIP	23446348
MIRT506196	hsa-miR-5047	PAR-CLIP	23446348
MIRT506195	hsa-miR-7150	PAR-CLIP	23446348
MIRT471146	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT471145	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT471144	hsa-miR-4781-3p	PAR-CLIP	23592263
MIRT471143	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT471142	hsa-miR-488-5p	PAR-CLIP	23592263
MIRT471141	hsa-miR-1470	PAR-CLIP	23592263
MIRT471140	hsa-miR-4667-3p	PAR-CLIP	23592263
MIRT471139	hsa-miR-1827	PAR-CLIP	23592263
MIRT471138	hsa-miR-218-1-3p	PAR-CLIP	23592263
MIRT471137	hsa-miR-659-3p	PAR-CLIP	23592263
MIRT471136	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT471134	hsa-miR-3125	PAR-CLIP	23592263
MIRT471135	hsa-miR-3916	PAR-CLIP	23592263
MIRT471133	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT471132	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471131	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT471130	hsa-miR-7974	PAR-CLIP	23592263
MIRT471129	hsa-miR-4656	PAR-CLIP	23592263
MIRT471128	hsa-miR-6829-5p	PAR-CLIP	23592263
MIRT471126	hsa-miR-4492	PAR-CLIP	23592263
MIRT471127	hsa-miR-4498	PAR-CLIP	23592263
MIRT471125	hsa-miR-5001-5p	PAR-CLIP	23592263
MIRT471124	hsa-miR-762	PAR-CLIP	23592263
MIRT471123	hsa-miR-4675	PAR-CLIP	23592263
MIRT471122	hsa-miR-4741	PAR-CLIP	23592263
MIRT471121	hsa-miR-363-5p	PAR-CLIP	23592263
MIRT471120	hsa-miR-6745	PAR-CLIP	23592263
MIRT471118	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT471119	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT471117	hsa-miR-1293	PAR-CLIP	23592263
MIRT471116	hsa-miR-4483	PAR-CLIP	23592263
MIRT471115	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT471114	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT471113	hsa-miR-4417	PAR-CLIP	23592263
MIRT471112	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT471110	hsa-miR-1587	PAR-CLIP	23592263
MIRT471111	hsa-miR-3620-5p	PAR-CLIP	23592263
MIRT439987	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439987	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT571824	hsa-miR-15a-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32312841
MIRT655180	hsa-miR-4640-3p	HITS-CLIP	23824327
MIRT655179	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT471141	hsa-miR-1470	HITS-CLIP	23824327
MIRT471140	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT655178	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT655177	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT655176	hsa-miR-4469	HITS-CLIP	23824327
MIRT655175	hsa-miR-3166	HITS-CLIP	23824327
MIRT655174	hsa-miR-4771	HITS-CLIP	23824327
MIRT655173	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT655172	hsa-miR-1273h-3p	HITS-CLIP	23824327
MIRT655171	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT655170	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT655169	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT571829	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT571828	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT571827	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT571825	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT571826	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT032068	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT571824	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT571823	hsa-miR-548ac	PAR-CLIP	20371350
MIRT571822	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT571821	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT571820	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT571819	hsa-miR-548z	PAR-CLIP	20371350
MIRT571818	hsa-miR-548ae-3p	PAR-CLIP	20371350
MIRT571817	hsa-miR-548ah-3p	PAR-CLIP	20371350
MIRT571815	hsa-miR-548aj-3p	PAR-CLIP	20371350
MIRT571816	hsa-miR-548am-3p	PAR-CLIP	20371350
MIRT571814	hsa-miR-548aq-3p	PAR-CLIP	20371350
MIRT571813	hsa-miR-548j-3p	PAR-CLIP	20371350
MIRT571812	hsa-miR-548x-3p	PAR-CLIP	20371350
MIRT571811	hsa-miR-548aa	PAR-CLIP	20371350
MIRT571810	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT571809	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT571808	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT571807	hsa-miR-4477a	PAR-CLIP	20371350
MIRT506210	hsa-miR-449a	PAR-CLIP	23446348
MIRT025582	hsa-miR-34a-5p	PAR-CLIP	23446348
MIRT506209	hsa-miR-34c-5p	PAR-CLIP	23446348
MIRT506208	hsa-miR-449b-5p	PAR-CLIP	23446348
MIRT506207	hsa-miR-223-3p	PAR-CLIP	23446348
MIRT506206	hsa-miR-3974	PAR-CLIP	23446348
MIRT506205	hsa-miR-5700	PAR-CLIP	23446348
MIRT506204	hsa-miR-4715-5p	PAR-CLIP	23446348
MIRT506203	hsa-miR-3126-3p	PAR-CLIP	23446348
MIRT506202	hsa-miR-1298-3p	PAR-CLIP	23446348
MIRT506201	hsa-miR-4490	PAR-CLIP	23446348
MIRT506200	hsa-miR-4774-5p	PAR-CLIP	23446348
MIRT506199	hsa-miR-4660	PAR-CLIP	23446348
MIRT506198	hsa-miR-548au-3p	PAR-CLIP	23446348
MIRT506197	hsa-miR-1301-3p	PAR-CLIP	23446348
MIRT506196	hsa-miR-5047	PAR-CLIP	23446348
MIRT506195	hsa-miR-7150	PAR-CLIP	23446348
MIRT471146	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT471145	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT471144	hsa-miR-4781-3p	PAR-CLIP	23592263
MIRT471143	hsa-miR-1245b-3p	PAR-CLIP	23592263
MIRT471142	hsa-miR-488-5p	PAR-CLIP	23592263
MIRT471141	hsa-miR-1470	PAR-CLIP	23592263
MIRT471140	hsa-miR-4667-3p	PAR-CLIP	23592263
MIRT471139	hsa-miR-1827	PAR-CLIP	23592263
MIRT471138	hsa-miR-218-1-3p	PAR-CLIP	23592263
MIRT471137	hsa-miR-659-3p	PAR-CLIP	23592263
MIRT471136	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT471134	hsa-miR-3125	PAR-CLIP	23592263
MIRT471135	hsa-miR-3916	PAR-CLIP	23592263
MIRT471133	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT471132	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471131	hsa-miR-6828-5p	PAR-CLIP	23592263
MIRT471130	hsa-miR-7974	PAR-CLIP	23592263
MIRT471129	hsa-miR-4656	PAR-CLIP	23592263
MIRT471128	hsa-miR-6829-5p	PAR-CLIP	23592263
MIRT471126	hsa-miR-4492	PAR-CLIP	23592263
MIRT471127	hsa-miR-4498	PAR-CLIP	23592263
MIRT471125	hsa-miR-5001-5p	PAR-CLIP	23592263
MIRT471124	hsa-miR-762	PAR-CLIP	23592263
MIRT471123	hsa-miR-4675	PAR-CLIP	23592263
MIRT471122	hsa-miR-4741	PAR-CLIP	23592263
MIRT471121	hsa-miR-363-5p	PAR-CLIP	23592263
MIRT471120	hsa-miR-6745	PAR-CLIP	23592263
MIRT471118	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT471119	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT471117	hsa-miR-1293	PAR-CLIP	23592263
MIRT471116	hsa-miR-4483	PAR-CLIP	23592263
MIRT471115	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT471114	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT471113	hsa-miR-4417	PAR-CLIP	23592263
MIRT471112	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT471110	hsa-miR-1587	PAR-CLIP	23592263
MIRT471111	hsa-miR-3620-5p	PAR-CLIP	23592263
MIRT1230580	hsa-miR-103a	CLIP-seq
MIRT1230581	hsa-miR-107	CLIP-seq
MIRT1230582	hsa-miR-1237	CLIP-seq
MIRT1230583	hsa-miR-1291	CLIP-seq
MIRT1230584	hsa-miR-1301	CLIP-seq
MIRT1230585	hsa-miR-1304	CLIP-seq
MIRT1230586	hsa-miR-1321	CLIP-seq
MIRT1230587	hsa-miR-138	CLIP-seq
MIRT1230588	hsa-miR-193a-5p	CLIP-seq
MIRT1230589	hsa-miR-203	CLIP-seq
MIRT1230590	hsa-miR-204	CLIP-seq
MIRT1230591	hsa-miR-211	CLIP-seq
MIRT1230592	hsa-miR-223	CLIP-seq
MIRT1230593	hsa-miR-2467-3p	CLIP-seq
MIRT1230594	hsa-miR-296-5p	CLIP-seq
MIRT1230595	hsa-miR-3065-3p	CLIP-seq
MIRT1230596	hsa-miR-3126-5p	CLIP-seq
MIRT1230597	hsa-miR-3150a-3p	CLIP-seq
MIRT1230598	hsa-miR-3151	CLIP-seq
MIRT1230599	hsa-miR-3153	CLIP-seq
MIRT1230600	hsa-miR-3158-3p	CLIP-seq
MIRT1230601	hsa-miR-3175	CLIP-seq
MIRT1230602	hsa-miR-3184	CLIP-seq
MIRT1230603	hsa-miR-342-5p	CLIP-seq
MIRT1230604	hsa-miR-34a	CLIP-seq
MIRT1230605	hsa-miR-3612	CLIP-seq
MIRT1230606	hsa-miR-3678-3p	CLIP-seq
MIRT1230607	hsa-miR-3688-5p	CLIP-seq
MIRT1230608	hsa-miR-3689a-3p	CLIP-seq
MIRT1230609	hsa-miR-3689c	CLIP-seq
MIRT1230610	hsa-miR-3919	CLIP-seq
MIRT1230611	hsa-miR-3922-5p	CLIP-seq
MIRT1230612	hsa-miR-3925-5p	CLIP-seq
MIRT1230613	hsa-miR-423-5p	CLIP-seq
MIRT1230614	hsa-miR-4283	CLIP-seq
MIRT1230615	hsa-miR-4297	CLIP-seq
MIRT1230616	hsa-miR-4303	CLIP-seq
MIRT1230617	hsa-miR-4308	CLIP-seq
MIRT1230618	hsa-miR-4316	CLIP-seq
MIRT1230619	hsa-miR-4419a	CLIP-seq
MIRT1230620	hsa-miR-4447	CLIP-seq
MIRT1230621	hsa-miR-4450	CLIP-seq
MIRT1230622	hsa-miR-4472	CLIP-seq
MIRT1230623	hsa-miR-4489	CLIP-seq
MIRT1230624	hsa-miR-449b	CLIP-seq
MIRT1230625	hsa-miR-4510	CLIP-seq
MIRT1230626	hsa-miR-4649-3p	CLIP-seq
MIRT1230627	hsa-miR-4649-5p	CLIP-seq
MIRT1230628	hsa-miR-4651	CLIP-seq
MIRT1230629	hsa-miR-4664-5p	CLIP-seq
MIRT1230630	hsa-miR-4667-5p	CLIP-seq
MIRT1230631	hsa-miR-4700-5p	CLIP-seq
MIRT1230632	hsa-miR-4710	CLIP-seq
MIRT1230633	hsa-miR-4728-5p	CLIP-seq
MIRT1230634	hsa-miR-4731-5p	CLIP-seq
MIRT1230635	hsa-miR-4739	CLIP-seq
MIRT1230636	hsa-miR-4756-5p	CLIP-seq
MIRT1230637	hsa-miR-4773	CLIP-seq
MIRT1230638	hsa-miR-491-5p	CLIP-seq
MIRT1230639	hsa-miR-541	CLIP-seq
MIRT1230640	hsa-miR-548q	CLIP-seq
MIRT1230641	hsa-miR-608	CLIP-seq
MIRT1230642	hsa-miR-623	CLIP-seq
MIRT1230643	hsa-miR-637	CLIP-seq
MIRT1230644	hsa-miR-646	CLIP-seq
MIRT1230645	hsa-miR-650	CLIP-seq
MIRT1230646	hsa-miR-765	CLIP-seq
MIRT1230647	hsa-miR-885-3p	CLIP-seq
MIRT1230648	hsa-miR-939	CLIP-seq
MIRT2067655	hsa-miR-1193	CLIP-seq
MIRT2067656	hsa-miR-1231	CLIP-seq
MIRT2067657	hsa-miR-23a	CLIP-seq
MIRT2067658	hsa-miR-23b	CLIP-seq
MIRT2067659	hsa-miR-23c	CLIP-seq
MIRT2067660	hsa-miR-346	CLIP-seq
MIRT2067661	hsa-miR-3691-5p	CLIP-seq
MIRT2067662	hsa-miR-370	CLIP-seq
MIRT2067663	hsa-miR-4288	CLIP-seq
MIRT2067664	hsa-miR-4491	CLIP-seq
MIRT2067665	hsa-miR-4643	CLIP-seq
MIRT2067666	hsa-miR-4657	CLIP-seq
MIRT1230630	hsa-miR-4667-5p	CLIP-seq
MIRT1230631	hsa-miR-4700-5p	CLIP-seq
MIRT2067667	hsa-miR-4752	CLIP-seq
MIRT2067668	hsa-miR-493	CLIP-seq
MIRT2067669	hsa-miR-632	CLIP-seq
MIRT2067670	hsa-miR-644	CLIP-seq
MIRT2067655	hsa-miR-1193	CLIP-seq
MIRT2295061	hsa-miR-147b	CLIP-seq
MIRT2295062	hsa-miR-15a	CLIP-seq
MIRT2295063	hsa-miR-15b	CLIP-seq
MIRT2295064	hsa-miR-16	CLIP-seq
MIRT2295065	hsa-miR-195	CLIP-seq
MIRT2295066	hsa-miR-210	CLIP-seq
MIRT2295067	hsa-miR-3192	CLIP-seq
MIRT2295068	hsa-miR-3650	CLIP-seq
MIRT2067661	hsa-miR-3691-5p	CLIP-seq
MIRT2295069	hsa-miR-424	CLIP-seq
MIRT1230617	hsa-miR-4308	CLIP-seq
MIRT2295070	hsa-miR-4455	CLIP-seq
MIRT2295071	hsa-miR-4481	CLIP-seq
MIRT2067664	hsa-miR-4491	CLIP-seq
MIRT2067665	hsa-miR-4643	CLIP-seq
MIRT2067666	hsa-miR-4657	CLIP-seq
MIRT2295072	hsa-miR-4745-5p	CLIP-seq
MIRT2067667	hsa-miR-4752	CLIP-seq
MIRT2295073	hsa-miR-497	CLIP-seq
MIRT2295074	hsa-miR-532-3p	CLIP-seq
MIRT2295075	hsa-miR-609	CLIP-seq
MIRT2295076	hsa-miR-671-5p	CLIP-seq
MIRT2067656	hsa-miR-1231	CLIP-seq
MIRT2456358	hsa-miR-1224-3p	CLIP-seq
MIRT2456359	hsa-miR-1254	CLIP-seq
MIRT2456360	hsa-miR-1260	CLIP-seq
MIRT2456361	hsa-miR-1260b	CLIP-seq
MIRT2456362	hsa-miR-1280	CLIP-seq
MIRT2456363	hsa-miR-1299	CLIP-seq
MIRT2456364	hsa-miR-150	CLIP-seq
MIRT2456365	hsa-miR-3116	CLIP-seq
MIRT2456366	hsa-miR-3978	CLIP-seq
MIRT2456367	hsa-miR-4254	CLIP-seq
MIRT2456368	hsa-miR-4434	CLIP-seq
MIRT2456369	hsa-miR-4516	CLIP-seq
MIRT2456370	hsa-miR-4531	CLIP-seq
MIRT2456371	hsa-miR-4650-5p	CLIP-seq
MIRT2456372	hsa-miR-4690-5p	CLIP-seq
MIRT2456373	hsa-miR-4713-5p	CLIP-seq
MIRT2295074	hsa-miR-532-3p	CLIP-seq
MIRT2456374	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0003677	Function	DNA binding	IBA
GO:0003682	Function	Chromatin binding	IBA
GO:0005515	Function	Protein binding	IPI	23104054, 23160351, 23455924, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006325	Process	Chromatin organization	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0019827	Process	Stem cell population maintenance	IEA
GO:0035098	Component	ESC/E(Z) complex	IDA	23104054
GO:0035098	Component	ESC/E(Z) complex	IEA
GO:0040029	Process	Epigenetic regulation of gene expression	IEA
GO:0045814	Process	Negative regulation of gene expression, epigenetic	IBA
GO:0045814	Process	Negative regulation of gene expression, epigenetic	IEA
GO:0045814	Process	Negative regulation of gene expression, epigenetic	IMP	23104054
GO:0046872	Function	Metal ion binding	IEA
GO:0048863	Process	Stem cell differentiation	IEA
GO:0140002	Function	Histone H3K4me3 reader activity	IEA
GO:0140003	Function	Histone H3K36me3 reader activity	IDA	23104054, 23160351, 23273982
GO:0140003	Function	Histone H3K36me3 reader activity	IEA

Other IDs

• MIM: 609740
• HGNC: 24566
• e!Ensembl: ENSG00000119403

Protein

• UniProt ID: Q5T6S3
• Protein name: PHD finger protein 19 (Polycomb-like protein 3) (hPCL3)
• Protein function: Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity (PubMed:15563832, PubMed:18691976, PubMed:23104054, PubMed:2316
• PDB: 2E5Q, 4BD3, 6NQ3, 6WAU
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF18104	Tudor_2	43 → 78	Jumonji domain-containing protein 2A Tudor domain	Domain
  PF00628	PHD	98 → 151	PHD-finger	Domain
  PF14061	Mtf2_C	531 → 578	Polycomb-like MTF2 factor 2	Domain

• Tissue specificity: TISSUE SPECIFICITY: Isoform 1 is expressed in thymus, heart, lung and kidney. Isoform 2 is predominantly expressed in placenta, skeletal muscle and kidney, whereas isoform 1 is predominantly expressed in liver and peripheral blood leukocytes. Overexpresse
• Sequence:

  MENRALDPGTRDSYGATSHLPNKGALAKVKNNFKDLMSKLTEGQYVLCRWTDGLYYLGKI
  KRVSSSKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCNICLGKTSGPLNEILICGKCG
  LGYHQQCHIPIAGSADQPLLTPWFCRRCIFALAVRKGGALKKGAIARTLQAVKMVLSYQP
  EELEWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWFHEACTQCLNEPMMFGDRFYL
  FFCSVCNQGPEYIERLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWELLQLGK
  LTSTPVTDRGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPGKLLPDKGLLPN
  ENSASSELRKRGKSKPGLLPHEFQQQKRRVYRRKRSKFLLEDAIPSSDFTSAWSTNHHLA
  SIFDFTLDEIQSLKSASSGQTFFSDVDSTDAASTSGSASTSLSYDSRWTVGSRKRKLAAK
  AYMPLRAKRWAAELDGRCPSDSSAEGASVPERPDEGIDSHTFESISEDDSSLSHLKSSIT
  NYFGAAGRLACGEKYQVLARRVTPEGKVQYLVEWEGTTPY

• Sequence length: 580

Pathways

KEGG:

Polycomb repressive complex

Reactome:

PRC2 methylates histones and DNA

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ASTHMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATOPIC ECZEMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORNEAL ASTIGMATISM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IMMUNE SYSTEM DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	18648537, 19714643, 34910834	Associate	★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	GWASDB_DG	21907864		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Astrocytoma	Astrocytoma	Pubtator	24260522	Associate	★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	GWASCAT_DG	21383967		★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	GWASDB_DG	21383967		★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	33894670	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	35069553	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	29874124		★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	GWASCAT_DG	30595370		★☆☆☆☆ Found in Text Mining only
Ewings sarcoma	Ewing sarcoma	BEFREE	29898995		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	24260522	Associate	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	30323224		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	30323224		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	28454437, 30131250		★☆☆☆☆ Found in Text Mining only
Immune System Diseases	Immune System Diseases	GWASDB_DG	21383967		★☆☆☆☆ Found in Text Mining only
Immune System Diseases	Immune System Diseases	GWASCAT_DG	21383967		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	15563832		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	29874124		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	31089138		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	22487681		★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	Pubtator	32949309	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	31383640		★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	32060406, 33894670	Associate	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	34390275	Stimulate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30131250, 30323224, 31383640		★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	Pubtator	34910834	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Carcinoma	Ovarian Carcinoma	BEFREE	29874124		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	29874124		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	32155117	Associate	★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	GWASDB_DG	17804836, 19503088, 24390342, 24782177		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Rheumatoid Arthritis	Rheumatoid arthritis	GWASCAT_DG	19503088, 24390342, 24782177, 30423114		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	19714643, 29423005		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Stomach Neoplasms	Stomach neoplasms	Pubtator	34078310	Associate	★☆☆☆☆ Found in Text Mining only
Wilms Tumor	Wilms tumor	Pubtator	32149111	Associate	★☆☆☆☆ Found in Text Mining only